IMP
Process View
regulation of signal transduction by p53 class mediator
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TP53 | tumor protein p53 | 0.993 | Mouse | |
| RB1 | retinoblastoma 1 | 0.882 | ||
| EP300 | E1A binding protein p300 | 0.690 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.682 | ||
| BRCA1 | breast cancer 1, early onset | 0.518 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.477 | ||
| BCAS2 | breast carcinoma amplified sequence 2 | 0.441 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.377 | Human | |
| TWIST1 | twist homolog 1 (Drosophila) | 0.298 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.229 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.194 | ||
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | 0.170 | ||
| ESR1 | estrogen receptor 1 | 0.156 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.154 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.147 | ||
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.138 | ||
| NBN | nibrin | 0.130 | ||
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.113 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.081 | Worm | |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.080 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.079 | ||
| MSN | moesin | 0.078 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.077 | ||
| RBM4 | RNA binding motif protein 4 | 0.076 | ||
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.075 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.075 | ||
| HIC2 | hypermethylated in cancer 2 | 0.063 | ||
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.059 | ||
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.057 | ||
| RIN1 | Ras and Rab interactor 1 | 0.056 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.055 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.054 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.047 | ||
| H3F3C | H3 histone, family 3C | 0.045 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.044 | ||
| DAXX | death-domain associated protein | 0.043 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.042 | ||
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.037 | ||
| RUNX1 | runt-related transcription factor 1 | 0.036 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.036 | ||
| GATA2 | GATA binding protein 2 | 0.036 | ||
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.035 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.032 | ||
| SF1 | splicing factor 1 | 0.031 | ||
| RYBP | RING1 and YY1 binding protein | 0.030 | ||
| WWOX | WW domain containing oxidoreductase | 0.027 | ||
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.026 | ||
| MYOD1 | myogenic differentiation 1 | 0.026 | ||
| CCND1 | cyclin D1 | 0.026 | ||
| RPS27L | ribosomal protein S27-like | 0.025 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.025 | ||
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.024 | ||
| ABI2 | abl-interactor 2 | 0.023 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.022 | ||
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.022 | ||
| CWC15 | CWC15 spliceosome-associated protein homolog (S. cerevisiae) | 0.021 | ||
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.021 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.021 | ||
| BCOR | BCL6 corepressor | 0.021 | ||
| SPRR2A | small proline-rich protein 2A | 0.020 | ||
| H2AFX | H2A histone family, member X | 0.020 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.019 | ||
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.019 | ||
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.019 | ||
| PLRG1 | pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) | 0.019 | Zebrafish | |
| HDAC2 | histone deacetylase 2 | 0.019 | ||
| EED | embryonic ectoderm development | 0.018 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.018 | ||
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.018 | ||
| HDAC1 | histone deacetylase 1 | 0.018 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.018 | ||
| EZR | ezrin | 0.017 | ||
| IARS | isoleucyl-tRNA synthetase | 0.017 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.016 | ||
| S100A4 | S100 calcium binding protein A4 | 0.016 | ||
| BAD | BCL2-associated agonist of cell death | 0.016 | ||
| TOP1 | topoisomerase (DNA) I | 0.016 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.015 | ||
| EGR1 | early growth response 1 | 0.015 | ||
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.015 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.015 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.015 | ||
| RBM4B | RNA binding motif protein 4B | 0.015 | ||
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.015 | ||
| ADSS | adenylosuccinate synthase | 0.014 | ||
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.014 | ||
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.014 | ||
| SSR4 | signal sequence receptor, delta (translocon-associated protein delta) | 0.014 | ||
| TCF12 | transcription factor 12 | 0.014 | ||
| ZNF420 | zinc finger protein 420 | 0.014 | ||
| TBCB | tubulin folding cofactor B | 0.014 | ||
| YAP1 | Yes-associated protein 1 | 0.014 | ||
| RBBP7 | retinoblastoma binding protein 7 | 0.014 | ||
| GORAB | golgin, RAB6-interacting | 0.013 | ||
| MSX2 | msh homeobox 2 | 0.013 | Human | |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.013 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.013 | ||
| CBX8 | chromobox homolog 8 | 0.013 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.013 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.013 | ||
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.013 | Human | |
| C11orf16 | chromosome 11 open reading frame 16 | 0.013 | ||
| MSX1 | msh homeobox 1 | 0.013 | ||
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.013 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.013 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.013 | ||
| LHX5 | LIM homeobox 5 | 0.013 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.013 | ||
| GATA4 | GATA binding protein 4 | 0.013 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.012 | ||
| ING2 | inhibitor of growth family, member 2 | 0.012 | ||
| SF3B14 | splicing factor 3B, 14 kDa subunit | 0.012 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.012 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.012 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.012 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.012 | ||
| FAM118B | family with sequence similarity 118, member B | 0.012 | ||
| NME2 | non-metastatic cells 2, protein (NM23B) expressed in | 0.012 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.012 | ||
| CTBP1 | C-terminal binding protein 1 | 0.012 | ||
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.011 | ||
| USP11 | ubiquitin specific peptidase 11 | 0.011 | ||
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.011 | ||
| PPP1R8 | protein phosphatase 1, regulatory (inhibitor) subunit 8 | 0.011 | ||
| ATMIN | ATM interactor | 0.011 | ||
| PML | promyelocytic leukemia | 0.011 | ||
| IL8 | interleukin 8 | 0.011 | ||
| NME1 | non-metastatic cells 1, protein (NM23A) expressed in | 0.011 | ||
| TSC22D1 | TSC22 domain family, member 1 | 0.011 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.011 | ||
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.011 | ||
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.011 | ||
| SFN | stratifin | 0.011 | ||
| RBM17 | RNA binding motif protein 17 | 0.011 | ||
| DCN | decorin | 0.010 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.010 | ||
| MSH5 | mutS homolog 5 (E. coli) | 0.010 | ||
| RNF20 | ring finger protein 20 | 0.010 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.010 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.010 |