IMP

Process View

Homo sapiens

13 genes annotated in human

response to fatty acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to fatty acid"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to fatty acid" (in gray)

Name	Description	Probability	Func Analog Organism
TGFB1	transforming growth factor, beta 1	0.968
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.946
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.913
IL8	interleukin 8	0.878
CCR5	chemokine (C-C motif) receptor 5	0.859
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.833
CCL4	chemokine (C-C motif) ligand 4	0.819	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.782	Rat
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.737	Human
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.692
PPARG	peroxisome proliferator-activated receptor gamma	0.683	Rat
ENG	endoglin	0.637	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.628
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.596
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.590
NME1	non-metastatic cells 1, protein (NM23A) expressed in	0.580
IL1B	interleukin 1, beta	0.539	Rat
CCL2	chemokine (C-C motif) ligand 2	0.506	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.486
FN1	fibronectin 1	0.467	Rat
CXCL9	chemokine (C-X-C motif) ligand 9	0.390
CCL8	chemokine (C-C motif) ligand 8	0.384	Human
CCL5	chemokine (C-C motif) ligand 5	0.277	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.253
CCL20	chemokine (C-C motif) ligand 20	0.213	Human
THBS1	thrombospondin 1	0.196
TICAM2	toll-like receptor adaptor molecule 2	0.178
S100B	S100 calcium binding protein B	0.156
CCL13	chemokine (C-C motif) ligand 13	0.138	Human
IL6	interleukin 6 (interferon, beta 2)	0.138
CCR7	chemokine (C-C motif) receptor 7	0.135
CYR61	cysteine-rich, angiogenic inducer, 61	0.127
CCL19	chemokine (C-C motif) ligand 19	0.122
FYN	FYN oncogene related to SRC, FGR, YES	0.110
ALDH1A1	aldehyde dehydrogenase 1 family, member A1	0.109
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.108
CDK2	cyclin-dependent kinase 2	0.096
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.096
CXCL5	chemokine (C-X-C motif) ligand 5	0.096
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.095	Human
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.094
CCL22	chemokine (C-C motif) ligand 22	0.093	Human
DPP4	dipeptidyl-peptidase 4	0.091
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.091	Rat
IL1R1	interleukin 1 receptor, type I	0.085
CCL3	chemokine (C-C motif) ligand 3	0.083	Human
FDPS	farnesyl diphosphate synthase	0.082
CXCL10	chemokine (C-X-C motif) ligand 10	0.069
IDE	insulin-degrading enzyme	0.067
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.060
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.056
VCAM1	vascular cell adhesion molecule 1	0.055
IL7R	interleukin 7 receptor	0.054
NRP1	neuropilin 1	0.053
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.048
PRMT2	protein arginine methyltransferase 2	0.047
PXN	paxillin	0.047
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.046
CXCL13	chemokine (C-X-C motif) ligand 13	0.043
CCNE1	cyclin E1	0.042
CCL7	chemokine (C-C motif) ligand 7	0.041	Human
TNF	tumor necrosis factor	0.039
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.039
TGFB3	transforming growth factor, beta 3	0.039
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.039
SELE	selectin E	0.038
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.035
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.034
SRGN	serglycin	0.034
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.034
TLR2	toll-like receptor 2	0.031
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.030
CDK1	cyclin-dependent kinase 1	0.029
CD83	CD83 molecule	0.029
CCR4	chemokine (C-C motif) receptor 4	0.027
IL1R2	interleukin 1 receptor, type II	0.027
CXCL11	chemokine (C-X-C motif) ligand 11	0.027
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.025
CDT1	chromatin licensing and DNA replication factor 1	0.024
TTR	transthyretin	0.024
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.023
NME3	non-metastatic cells 3, protein expressed in	0.022
NME4	non-metastatic cells 4, protein expressed in	0.021
DARC	Duffy blood group, chemokine receptor	0.021
CAV1	caveolin 1, caveolae protein, 22kDa	0.021
CCL11	chemokine (C-C motif) ligand 11	0.021	Human
CD36	CD36 molecule (thrombospondin receptor)	0.021
IFNG	interferon, gamma	0.021
LY96	lymphocyte antigen 96	0.021
BCL2A1	BCL2-related protein A1	0.020
IL2RB	interleukin 2 receptor, beta	0.019
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.019
GRB2	growth factor receptor-bound protein 2	0.019
IL10	interleukin 10	0.019
ESRRG	estrogen-related receptor gamma	0.019
CXCL12	chemokine (C-X-C motif) ligand 12	0.019
ACACA	acetyl-CoA carboxylase alpha	0.019
SREBF2	sterol regulatory element binding transcription factor 2	0.019
RGS1	regulator of G-protein signaling 1	0.018
CCNA2	cyclin A2	0.018
ITK	IL2-inducible T-cell kinase	0.018
MED15	mediator complex subunit 15	0.018
STAT4	signal transducer and activator of transcription 4	0.017
CSF1	colony stimulating factor 1 (macrophage)	0.017
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.017
FSTL1	follistatin-like 1	0.017
AQP7	aquaporin 7	0.017
GRAP2	GRB2-related adaptor protein 2	0.015
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.015
CCR1	chemokine (C-C motif) receptor 1	0.014
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.014
FPR3	formyl peptide receptor 3	0.014
CH25H	cholesterol 25-hydroxylase	0.014
SMAD7	SMAD family member 7	0.014
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.014
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.014
RPL38	ribosomal protein L38	0.014
CAV2	caveolin 2	0.014
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
CCR3	chemokine (C-C motif) receptor 3	0.013
EBP	emopamil binding protein (sterol isomerase)	0.013
FKBP1A	FK506 binding protein 1A, 12kDa	0.013
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.012
CCL1	chemokine (C-C motif) ligand 1	0.012	Human
IPO13	importin 13	0.012
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
CMIP	c-Maf-inducing protein	0.012
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.012
FLNA	filamin A, alpha	0.012
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.012
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.012
C2orf18	chromosome 2 open reading frame 18	0.011
ARRB1	arrestin, beta 1	0.011
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.011
HTT	huntingtin	0.011
IRF4	interferon regulatory factor 4	0.011
IL2RG	interleukin 2 receptor, gamma	0.011
IER3	immediate early response 3	0.011
IL21R	interleukin 21 receptor	0.010
CD69	CD69 molecule	0.010
NLRP3	NLR family, pyrin domain containing 3	0.010
AQP9	aquaporin 9	0.010
SIRT3	sirtuin 3	0.010
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.010