IMP

Process View

Homo sapiens

20 genes annotated in human

regulation of focal adhesion assembly

Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of focal adhesion assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of focal adhesion assembly" (in gray)

Name	Description	Probability	Func Analog Organism
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.999	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.998	Human
VEGFA	vascular endothelial growth factor A	0.990
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.971	Human
PTK2	PTK2 protein tyrosine kinase 2	0.911
NRP1	neuropilin 1	0.898
S100A6	S100 calcium binding protein A6	0.897	Human
S100A8	S100 calcium binding protein A8	0.887	Human
S100B	S100 calcium binding protein B	0.876	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.857
S100A9	S100 calcium binding protein A9	0.808	Human
FKBP1A	FK506 binding protein 1A, 12kDa	0.699
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.692
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.658	Human
ENG	endoglin	0.581
SMAD2	SMAD family member 2	0.541
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.485
BCAR1	breast cancer anti-estrogen resistance 1	0.470
FHL2	four and a half LIM domains 2	0.467
LGALS1	lectin, galactoside-binding, soluble, 1	0.457
S100A11	S100 calcium binding protein A11	0.448	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.426
NCK2	NCK adaptor protein 2	0.426
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.415	Human
ANXA2	annexin A2	0.396
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.395
BMP2	bone morphogenetic protein 2	0.335
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.322
LIMS1	LIM and senescent cell antigen-like domains 1	0.321
EPHA7	EPH receptor A7	0.312	Human
ANGPT2	angiopoietin 2	0.295
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.288
S100A1	S100 calcium binding protein A1	0.275	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.269
EPHA2	EPH receptor A2	0.265	Human
EFNA1	ephrin-A1	0.257	Human
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.241
RHOA	ras homolog gene family, member A	0.223
SMAD7	SMAD family member 7	0.208
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.196	Human
LPXN	leupaxin	0.166	Human
PGF	placental growth factor	0.165	Human
PLCG1	phospholipase C, gamma 1	0.162
FKBP4	FK506 binding protein 4, 59kDa	0.144
TGFB1	transforming growth factor, beta 1	0.135
TSC2	tuberous sclerosis 2	0.126
GDF5	growth differentiation factor 5	0.121
EGFR	epidermal growth factor receptor	0.118
ACVR1	activin A receptor, type I	0.116	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.109	Human
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.106
TGFB3	transforming growth factor, beta 3	0.095
PTPRB	protein tyrosine phosphatase, receptor type, B	0.085	Human
GRB7	growth factor receptor-bound protein 7	0.075
PDGFA	platelet-derived growth factor alpha polypeptide	0.066	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.065
GAB1	GRB2-associated binding protein 1	0.062
AREG	amphiregulin	0.062
BMPR1A	bone morphogenetic protein receptor, type IA	0.059	Human
TSG101	tumor susceptibility gene 101	0.058
PDGFC	platelet derived growth factor C	0.057
TRIP6	thyroid hormone receptor interactor 6	0.056
ZNF746	zinc finger protein 746	0.052
ANGPT1	angiopoietin 1	0.051
AHNAK	AHNAK nucleoprotein	0.051
CD63	CD63 molecule	0.050
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.047
S100A2	S100 calcium binding protein A2	0.045	Human
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.045
ATF7IP	activating transcription factor 7 interacting protein	0.043
GHR	growth hormone receptor	0.042
TMSB10	thymosin beta 10	0.041
KITLG	KIT ligand	0.041
EFNA5	ephrin-A5	0.039
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.038
FN1	fibronectin 1	0.038
EZR	ezrin	0.038
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036
EMP3	epithelial membrane protein 3	0.036
CAPG	capping protein (actin filament), gelsolin-like	0.035
AGER	advanced glycosylation end product-specific receptor	0.034
BMP4	bone morphogenetic protein 4	0.034
S100A4	S100 calcium binding protein A4	0.034	Human
ILK	integrin-linked kinase	0.033
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.033
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.032
FURIN	furin (paired basic amino acid cleaving enzyme)	0.032
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.031
DPYSL4	dihydropyrimidinase-like 4	0.030
FAF1	Fas (TNFRSF6) associated factor 1	0.030
GORAB	golgin, RAB6-interacting	0.029
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.029	Human
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.029
JAG1	jagged 1	0.028
TIMP2	TIMP metallopeptidase inhibitor 2	0.028
HOXA1	homeobox A1	0.028
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.026
ANXA5	annexin A5	0.026
SLA	Src-like-adaptor	0.025
LIMK1	LIM domain kinase 1	0.025
LDLR	low density lipoprotein receptor	0.025
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.024
DIAPH1	diaphanous homolog 1 (Drosophila)	0.024
FLT4	fms-related tyrosine kinase 4	0.023	Human
LGALS3	lectin, galactoside-binding, soluble, 3	0.023
RRAS	related RAS viral (r-ras) oncogene homolog	0.022
PRKG1	protein kinase, cGMP-dependent, type I	0.022
TGFBR1	transforming growth factor, beta receptor 1	0.022	Human
SKIL	SKI-like oncogene	0.021
ZMYND11	zinc finger, MYND-type containing 11	0.021
NCF1	neutrophil cytosolic factor 1	0.020
ANXA1	annexin A1	0.020
EFNB2	ephrin-B2	0.020	Human
FXYD5	FXYD domain containing ion transport regulator 5	0.020
LMNA	lamin A/C	0.019
TIMP1	TIMP metallopeptidase inhibitor 1	0.019
CAV1	caveolin 1, caveolae protein, 22kDa	0.018
ITGA6	integrin, alpha 6	0.018
ITGA7	integrin, alpha 7	0.018
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.017
S100A12	S100 calcium binding protein A12	0.017	Human
PHC2	polyhomeotic homolog 2 (Drosophila)	0.017
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.017
CNKSR1	connector enhancer of kinase suppressor of Ras 1	0.017
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.017
NRP2	neuropilin 2	0.016
VCL	vinculin	0.016
TAGLN2	transgelin 2	0.016
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.015
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.015
SFN	stratifin	0.015
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.015
JUP	junction plakoglobin	0.015
RHOG	ras homolog gene family, member G (rho G)	0.015	Human
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.015
MSN	moesin	0.014
IQGAP1	IQ motif containing GTPase activating protein 1	0.014
BMP1	bone morphogenetic protein 1	0.014
FEM1B	fem-1 homolog b (C. elegans)	0.014
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.014
PSG5	pregnancy specific beta-1-glycoprotein 5	0.014
S100A10	S100 calcium binding protein A10	0.014
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.013
TSPO	translocator protein (18kDa)	0.013
EPHB3	EPH receptor B3	0.013	Human
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.013
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.013
WISP2	WNT1 inducible signaling pathway protein 2	0.013
PDE2A	phosphodiesterase 2A, cGMP-stimulated	0.012
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.012
LAT	linker for activation of T cells	0.012
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.012
CD9	CD9 molecule	0.012
COL2A1	collagen, type II, alpha 1	0.012
CSTA	cystatin A (stefin A)	0.012
USP2	ubiquitin specific peptidase 2	0.012
AR	androgen receptor	0.012
MAPK8	mitogen-activated protein kinase 8	0.012
EPHA3	EPH receptor A3	0.012
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.012
SPARCL1	SPARC-like 1 (hevin)	0.012
APC	adenomatous polyposis coli	0.012
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.012
TGFB2	transforming growth factor, beta 2	0.012
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.011
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.011
GRB10	growth factor receptor-bound protein 10	0.011
BBS10	Bardet-Biedl syndrome 10	0.011
RHOU	ras homolog gene family, member U	0.011
PTEN	phosphatase and tensin homolog	0.010
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.010
TIMP3	TIMP metallopeptidase inhibitor 3	0.010
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.010
EFHD2	EF-hand domain family, member D2	0.010
COL6A1	collagen, type VI, alpha 1	0.010