IMP

Process View

Homo sapiens

4 genes annotated in human

regulation of platelet aggregation

Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of platelet aggregation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of platelet aggregation" (in gray)

Name	Description	Probability	Func Analog Organism
C1QA	complement component 1, q subcomponent, A chain	0.999	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.973
NCF1	neutrophil cytosolic factor 1	0.951
C1QC	complement component 1, q subcomponent, C chain	0.945	Human
C1QB	complement component 1, q subcomponent, B chain	0.904	Human
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.770
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.698
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.564
ACTB	actin, beta	0.552
BLNK	B-cell linker	0.536
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.527
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.436
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.434
TRIM9	tripartite motif containing 9	0.398
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.254
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.198
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.188
PRKCA	protein kinase C, alpha	0.169
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.168
SH3KBP1	SH3-domain kinase binding protein 1	0.150
NCF4	neutrophil cytosolic factor 4, 40kDa	0.146
BTK	Bruton agammaglobulinemia tyrosine kinase	0.144
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.142
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.127
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.116
HDAC6	histone deacetylase 6	0.112
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.104
CDCP1	CUB domain containing protein 1	0.102
PRKCD	protein kinase C, delta	0.096	Mouse
CYBA	cytochrome b-245, alpha polypeptide	0.096
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.089
EGFR	epidermal growth factor receptor	0.084
SH3BP2	SH3-domain binding protein 2	0.072
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.072
IL32	interleukin 32	0.069
PRKCB	protein kinase C, beta	0.067	Human
VAV1	vav 1 guanine nucleotide exchange factor	0.066
MARCO	macrophage receptor with collagenous structure	0.064
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.063
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.060
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.059
ARRDC3	arrestin domain containing 3	0.058
SPRY4	sprouty homolog 4 (Drosophila)	0.055
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.052
CARD11	caspase recruitment domain family, member 11	0.047
RICTOR	RPTOR independent companion of MTOR, complex 2	0.047
KRT5	keratin 5	0.045
ADAM15	ADAM metallopeptidase domain 15	0.044
LCK	lymphocyte-specific protein tyrosine kinase	0.044
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.041
TYROBP	TYRO protein tyrosine kinase binding protein	0.039
MYH9	myosin, heavy chain 9, non-muscle	0.038
HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase	0.038
SH2D2A	SH2 domain containing 2A	0.038
DCN	decorin	0.037
MRVI1	murine retrovirus integration site 1 homolog	0.034
COMP	cartilage oligomeric matrix protein	0.033
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.030
MPEG1	macrophage expressed 1	0.028
BCL3	B-cell CLL/lymphoma 3	0.027
GLRX3	glutaredoxin 3	0.027
GAB2	GRB2-associated binding protein 2	0.027
STAB1	stabilin 1	0.026
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.026
CSF1R	colony stimulating factor 1 receptor	0.026
MYO1D	myosin ID	0.025
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.025
C1R	complement component 1, r subcomponent	0.024
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.023
RALBP1	ralA binding protein 1	0.023
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.023
CYTH1	cytohesin 1	0.023
AVPR2	arginine vasopressin receptor 2	0.022
COL8A2	collagen, type VIII, alpha 2	0.022
CDKL5	cyclin-dependent kinase-like 5	0.021
COL13A1	collagen, type XIII, alpha 1	0.021
CD247	CD247 molecule	0.021
LAT	linker for activation of T cells	0.021
EMILIN2	elastin microfibril interfacer 2	0.020
C4B	complement component 4B (Chido blood group)	0.020
TLR7	toll-like receptor 7	0.020
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.020
VSIG4	V-set and immunoglobulin domain containing 4	0.020
C1S	complement component 1, s subcomponent	0.020
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.019
WISP1	WNT1 inducible signaling pathway protein 1	0.019
MSN	moesin	0.019
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.018	Human
TREM2	triggering receptor expressed on myeloid cells 2	0.018
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.018
APOC1	apolipoprotein C-I	0.018
PRKCQ	protein kinase C, theta	0.018	Mouse
MAPK8	mitogen-activated protein kinase 8	0.018
CD68	CD68 molecule	0.018
C10orf72	chromosome 10 open reading frame 72	0.018
PASK	PAS domain containing serine/threonine kinase	0.018
TMEM176B	transmembrane protein 176B	0.017
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.017
SYK	spleen tyrosine kinase	0.017	Mouse
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.017
C3	complement component 3	0.017
AXL	AXL receptor tyrosine kinase	0.017
MS4A7	membrane-spanning 4-domains, subfamily A, member 7	0.017
MSR1	macrophage scavenger receptor 1	0.017
SLAMF8	SLAM family member 8	0.017
LMNA	lamin A/C	0.017
TRIM41	tripartite motif containing 41	0.017
CSK	c-src tyrosine kinase	0.016
OLFML2B	olfactomedin-like 2B	0.016
VAV2	vav 2 guanine nucleotide exchange factor	0.016
GGT5	gamma-glutamyltransferase 5	0.016
CD248	CD248 molecule, endosialin	0.016
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.016
EXT2	exostosin 2	0.016
EZR	ezrin	0.016
PRKCE	protein kinase C, epsilon	0.016	Human
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.016
COL6A1	collagen, type VI, alpha 1	0.016
PTPRC	protein tyrosine phosphatase, receptor type, C	0.016
MUC1	mucin 1, cell surface associated	0.016
SKAP1	src kinase associated phosphoprotein 1	0.016
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.016
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.016
RGS4	regulator of G-protein signaling 4	0.016
HIPK3	homeodomain interacting protein kinase 3	0.015
PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.015
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.015
PRRX2	paired related homeobox 2	0.015
SOX18	SRY (sex determining region Y)-box 18	0.015
COL14A1	collagen, type XIV, alpha 1	0.015
ALAS1	aminolevulinate, delta-, synthase 1	0.015
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.014
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.014
BEAN1	brain expressed, associated with NEDD4, 1	0.014
SH2D1A	SH2 domain containing 1A	0.014
PLIN4	perilipin 4	0.014
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.014
PTEN	phosphatase and tensin homolog	0.014
LRRC8C	leucine rich repeat containing 8 family, member C	0.014
CD37	CD37 molecule	0.014
APOE	apolipoprotein E	0.014
AKAP12	A kinase (PRKA) anchor protein 12	0.014
CRIP2	cysteine-rich protein 2	0.014
ANGPTL2	angiopoietin-like 2	0.014
ELN	elastin	0.014
NGFR	nerve growth factor receptor	0.014
RET	ret proto-oncogene	0.013
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.013
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.013
FOXF2	forkhead box F2	0.013
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.013
ADRBK1	adrenergic, beta, receptor kinase 1	0.013
PTPRA	protein tyrosine phosphatase, receptor type, A	0.013
MMP19	matrix metallopeptidase 19	0.013
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.013
OSMR	oncostatin M receptor	0.013
DOK5	docking protein 5	0.013
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.013
SPON2	spondin 2, extracellular matrix protein	0.013
SCARF2	scavenger receptor class F, member 2	0.013
JPH3	junctophilin 3	0.013
HOXD8	homeobox D8	0.013
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.013
SLC25A47	solute carrier family 25, member 47	0.013
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.013
SRCIN1	SRC kinase signaling inhibitor 1	0.013
KIRREL	kin of IRRE like (Drosophila)	0.012
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.012
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.012
AHNAK	AHNAK nucleoprotein	0.012
COL6A2	collagen, type VI, alpha 2	0.012
ITM2A	integral membrane protein 2A	0.012
FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	0.012
STAC	SH3 and cysteine rich domain	0.012
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.012
SIRPB1	signal-regulatory protein beta 1	0.012
SIX2	SIX homeobox 2	0.012
ACVRL1	activin A receptor type II-like 1	0.012
SOS2	son of sevenless homolog 2 (Drosophila)	0.012
GDF9	growth differentiation factor 9	0.012
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.012
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.012
CHRD	chordin	0.012
FKBP10	FK506 binding protein 10, 65 kDa	0.012
CENPV	centromere protein V	0.012
DOK6	docking protein 6	0.012
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.012
VWF	von Willebrand factor	0.012
EFS	embryonal Fyn-associated substrate	0.012
CLDN11	claudin 11	0.012
CMKLR1	chemokine-like receptor 1	0.012
THY1	Thy-1 cell surface antigen	0.012
HIC1	hypermethylated in cancer 1	0.012
A2M	alpha-2-macroglobulin	0.012
WISP2	WNT1 inducible signaling pathway protein 2	0.012
MRGPRF	MAS-related GPR, member F	0.011
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.011
ADAP2	ArfGAP with dual PH domains 2	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
A1BG	alpha-1-B glycoprotein	0.011
DLGAP3	discs, large (Drosophila) homolog-associated protein 3	0.011
C1QTNF2	C1q and tumor necrosis factor related protein 2	0.011	Human
LRMP	lymphoid-restricted membrane protein	0.011
SEMA5B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.011
CNTNAP1	contactin associated protein 1	0.011
GPR124	G protein-coupled receptor 124	0.011
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.011
TOM1L1	target of myb1 (chicken)-like 1	0.011
BAI1	brain-specific angiogenesis inhibitor 1	0.011
GLI2	GLI family zinc finger 2	0.011
ACP5	acid phosphatase 5, tartrate resistant	0.011
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.011
CD4	CD4 molecule	0.011
ZNF431	zinc finger protein 431	0.011
CDH5	cadherin 5, type 2 (vascular endothelium)	0.011
NKD2	naked cuticle homolog 2 (Drosophila)	0.011
DNM1	dynamin 1	0.011
LEP	leptin	0.011
PODN	podocan	0.011
CCL13	chemokine (C-C motif) ligand 13	0.011
SOS1	son of sevenless homolog 1 (Drosophila)	0.011
EN1	engrailed homeobox 1	0.011
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.011
CRYBA2	crystallin, beta A2	0.011
COL4A1	collagen, type IV, alpha 1	0.011
KCNK9	potassium channel, subfamily K, member 9	0.011
EMILIN1	elastin microfibril interfacer 1	0.011
HSF2BP	heat shock transcription factor 2 binding protein	0.011
ZNF469	zinc finger protein 469	0.011
PCDH12	protocadherin 12	0.011
TMSB4X	thymosin beta 4, X-linked	0.011
F13A1	coagulation factor XIII, A1 polypeptide	0.011
GPR4	G protein-coupled receptor 4	0.011
DGKA	diacylglycerol kinase, alpha 80kDa	0.011
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.011
HES2	hairy and enhancer of split 2 (Drosophila)	0.011
DOCK7	dedicator of cytokinesis 7	0.011
KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	0.011
CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.011
DDR2	discoidin domain receptor tyrosine kinase 2	0.011
SLC15A3	solute carrier family 15, member 3	0.011
PLTP	phospholipid transfer protein	0.011
CRHR1	corticotropin releasing hormone receptor 1	0.011
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.011
EBF2	early B-cell factor 2	0.011
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.011
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.011	Human
MED28	mediator complex subunit 28	0.011
TGFA	transforming growth factor, alpha	0.010
ITGA11	integrin, alpha 11	0.010
CREB3L1	cAMP responsive element binding protein 3-like 1	0.010
LOXL2	lysyl oxidase-like 2	0.010
CD2	CD2 molecule	0.010
DARC	Duffy blood group, chemokine receptor	0.010
HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	0.010
TMEM176A	transmembrane protein 176A	0.010
FOXS1	forkhead box S1	0.010
SYNGR3	synaptogyrin 3	0.010
MOXD1	monooxygenase, DBH-like 1	0.010
FASLG	Fas ligand (TNF superfamily, member 6)	0.010
DAAM2	dishevelled associated activator of morphogenesis 2	0.010
FGFR1	fibroblast growth factor receptor 1	0.010
DPT	dermatopontin	0.010
PDE3A	phosphodiesterase 3A, cGMP-inhibited	0.010
SH2B2	SH2B adaptor protein 2	0.010
FBLN2	fibulin 2	0.010
UBASH3B	ubiquitin associated and SH3 domain containing B	0.010	Mouse
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.010
PTPRO	protein tyrosine phosphatase, receptor type, O	0.010
AJAP1	adherens junctions associated protein 1	0.010
CSAD	cysteine sulfinic acid decarboxylase	0.010
CORO1C	coronin, actin binding protein, 1C	0.010
GPR176	G protein-coupled receptor 176	0.010
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.010
CLSTN2	calsyntenin 2	0.010
EPHB2	EPH receptor B2	0.010
SNTG2	syntrophin, gamma 2	0.010
SIRPA	signal-regulatory protein alpha	0.010
PTK6	PTK6 protein tyrosine kinase 6	0.010