The network for 'regulation of platelet aggregation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of platelet aggregation

Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.

Homo sapiens
Name Description Probability Func Analog Organism
C1QA complement component 1, q subcomponent, A chain 0.999
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.973
NCF1 neutrophil cytosolic factor 1 0.951
C1QC complement component 1, q subcomponent, C chain 0.945
C1QB complement component 1, q subcomponent, B chain 0.904
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.770
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.698
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.564
ACTB actin, beta 0.552
BLNK B-cell linker 0.536
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.527
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.436
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.434
TRIM9 tripartite motif containing 9 0.398
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.254
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.198
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.188
PRKCA protein kinase C, alpha 0.169
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.168
SH3KBP1 SH3-domain kinase binding protein 1 0.150
NCF4 neutrophil cytosolic factor 4, 40kDa 0.146
BTK Bruton agammaglobulinemia tyrosine kinase 0.144
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.142
PTK2B PTK2B protein tyrosine kinase 2 beta 0.127
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.116
HDAC6 histone deacetylase 6 0.112
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.104
CDCP1 CUB domain containing protein 1 0.102
PRKCD protein kinase C, delta 0.096
CYBA cytochrome b-245, alpha polypeptide 0.096
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.089
EGFR epidermal growth factor receptor 0.084
SH3BP2 SH3-domain binding protein 2 0.072
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.072
IL32 interleukin 32 0.069
PRKCB protein kinase C, beta 0.067
VAV1 vav 1 guanine nucleotide exchange factor 0.066
MARCO macrophage receptor with collagenous structure 0.064
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.063
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.060
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.059
ARRDC3 arrestin domain containing 3 0.058
SPRY4 sprouty homolog 4 (Drosophila) 0.055
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.052
CARD11 caspase recruitment domain family, member 11 0.047
RICTOR RPTOR independent companion of MTOR, complex 2 0.047
KRT5 keratin 5 0.045
ADAM15 ADAM metallopeptidase domain 15 0.044
LCK lymphocyte-specific protein tyrosine kinase 0.044
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.041
TYROBP TYRO protein tyrosine kinase binding protein 0.039
MYH9 myosin, heavy chain 9, non-muscle 0.038
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.038
SH2D2A SH2 domain containing 2A 0.038
DCN decorin 0.037
MRVI1 murine retrovirus integration site 1 homolog 0.034
COMP cartilage oligomeric matrix protein 0.033
MET met proto-oncogene (hepatocyte growth factor receptor) 0.030
MPEG1 macrophage expressed 1 0.028
BCL3 B-cell CLL/lymphoma 3 0.027
GLRX3 glutaredoxin 3 0.027
GAB2 GRB2-associated binding protein 2 0.027
STAB1 stabilin 1 0.026
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.026
CSF1R colony stimulating factor 1 receptor 0.026
MYO1D myosin ID 0.025
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 0.025
C1R complement component 1, r subcomponent 0.024
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.023
RALBP1 ralA binding protein 1 0.023
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.023
CYTH1 cytohesin 1 0.023
AVPR2 arginine vasopressin receptor 2 0.022
COL8A2 collagen, type VIII, alpha 2 0.022
CDKL5 cyclin-dependent kinase-like 5 0.021
COL13A1 collagen, type XIII, alpha 1 0.021
CD247 CD247 molecule 0.021
LAT linker for activation of T cells 0.021
EMILIN2 elastin microfibril interfacer 2 0.020
C4B complement component 4B (Chido blood group) 0.020
TLR7 toll-like receptor 7 0.020
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.020
VSIG4 V-set and immunoglobulin domain containing 4 0.020
C1S complement component 1, s subcomponent 0.020
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.019
WISP1 WNT1 inducible signaling pathway protein 1 0.019
MSN moesin 0.019
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.018
TREM2 triggering receptor expressed on myeloid cells 2 0.018
ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 0.018
APOC1 apolipoprotein C-I 0.018
PRKCQ protein kinase C, theta 0.018
MAPK8 mitogen-activated protein kinase 8 0.018
CD68 CD68 molecule 0.018
C10orf72 chromosome 10 open reading frame 72 0.018
PASK PAS domain containing serine/threonine kinase 0.018
TMEM176B transmembrane protein 176B 0.017
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.017
SYK spleen tyrosine kinase 0.017
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.017
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.394
Ptprc protein tyrosine phosphatase, receptor type, C 0.118
Ldb3 LIM domain binding 3 0.092
Ikzf1 IKAROS family zinc finger 1 0.064
Fyn Fyn proto-oncogene 0.054
Actn2 actinin alpha 2 0.050
Grb2 growth factor receptor bound protein 2 0.048
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.041
Cd19 CD19 antigen 0.039
Cd247 CD247 antigen 0.037
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.035
Blnk B-cell linker 0.032
Lat linker for activation of T cells 0.030
Plcg2 phospholipase C, gamma 2 0.028
Cd28 CD28 antigen 0.025
Was Wiskott-Aldrich syndrome homolog (human) 0.024
Cd40 CD40 antigen 0.024
Alox5ap arachidonate 5-lipoxygenase activating protein 0.023
Igh immunoglobulin heavy chain complex 0.022
ND6 NADH dehydrogenase subunit 6 0.022
Fas Fas (TNF receptor superfamily member 6) 0.018
Cd22 CD22 antigen 0.017
Prkce protein kinase C, epsilon 0.016
Il2rg interleukin 2 receptor, gamma chain 0.015
Ptk2 PTK2 protein tyrosine kinase 2 0.014
Inpp5d inositol polyphosphate-5-phosphatase D 0.013
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.012
Clock circadian locomotor output cycles kaput 0.011
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.011
Ptpre protein tyrosine phosphatase, receptor type, E 0.011
Pou2af1 POU domain, class 2, associating factor 1 0.011
Dok1 docking protein 1 0.011
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.011
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.053
Gna15 guanine nucleotide binding protein, alpha 15 0.047
Cd247 Cd247 molecule 0.046
Cd5 Cd5 molecule 0.038
Cd37 CD37 molecule 0.038
Tacr2 tachykinin receptor 2 0.033
Cd38 CD38 molecule 0.031
Gja1 gap junction protein, alpha 1 0.031
Cd79b Cd79b molecule, immunoglobulin-associated beta 0.028
Syt8 synaptotagmin VIII 0.027
Fgf14 fibroblast growth factor 14 0.026
Sstr1 somatostatin receptor 1 0.025
Cd8b CD8b molecule 0.024
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.023
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.022
Cpa3 carboxypeptidase A3, mast cell 0.022
Plau plasminogen activator, urokinase 0.021
Gja3 gap junction protein, alpha 3 0.019
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.018
Gad2 glutamate decarboxylase 2 0.017
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.016
Tlr4 toll-like receptor 4 0.016
Arl11 ADP-ribosylation factor-like 11 0.016
Olr1500 olfactory receptor 1500 0.016
Fgfr2 fibroblast growth factor receptor 2 0.016
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.015
Ptafr platelet-activating factor receptor 0.015
Myog myogenin 0.015
Musk muscle, skeletal, receptor tyrosine kinase 0.015
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.014
Mfrp membrane frizzled-related protein 0.014
Phkg1 phosphorylase kinase, gamma 1 0.014
Edn1 endothelin 1 0.014
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.014
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.014
Olr416 olfactory receptor 416 0.014
Gcm1 glial cells missing homolog 1 (Drosophila) 0.013
Svs1 seminal vesicle secretory protein 1 0.013
Inpp5d inositol polyphosphate-5-phosphatase D 0.013
Acrv1 acrosomal vesicle protein 1 0.013
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.013
Grifin galectin-related inter-fiber protein 0.013
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.013
Adora2a adenosine A2a receptor 0.013
Dlx5 distal-less homeobox 5 0.013
Cma1 chymase 1, mast cell 0.012
Agtr1a angiotensin II receptor, type 1a 0.012
C1qtnf6 C1q and tumor necrosis factor related protein 6 0.012
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.012
Tusc3 tumor suppressor candidate 3 0.012
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.012
Egr3 early growth response 3 0.012
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.012
Cxcr5 chemokine (C-X-C motif) receptor 5 0.012
Hnmt histamine N-methyltransferase 0.012
Tcrb T-cell receptor beta chain 0.012
A3galt2 alpha 1,3-galactosyltransferase 2 0.012
Vav1 vav 1 guanine nucleotide exchange factor 0.012
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.012
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.012
Zg16 zymogen granule protein 16 0.012
Insrr insulin receptor-related receptor 0.012
Esr1 estrogen receptor 1 0.012
Itgb7 integrin, beta 7 0.011
Mmp9 matrix metallopeptidase 9 0.011
Slco1c1 solute carrier organic anion transporter family, member 1c1 0.011
Kcnq2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.011
Ier5 immediate early response 5 0.011
Fgf2 fibroblast growth factor 2 0.011
Il1rn interleukin 1 receptor antagonist 0.011
Rab11a RAB11a, member RAS oncogene family 0.011
Csrnp2 cysteine-serine-rich nuclear protein 2 0.011
Aard alanine and arginine rich domain containing protein 0.011
Cmklr1 chemokine-like receptor 1 0.011
Reg3a regenerating islet-derived 3 alpha 0.011
Cd4 Cd4 molecule 0.011
Npy5r neuropeptide Y receptor Y5 0.011
Svs3a seminal vesicle secretory protein 3A 0.011
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.011
RGD1564664 similar to LOC387763 protein 0.010
Prrx1 paired related homeobox 1 0.010
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.010
Dock8 dedicator of cytokinesis 8 0.010
RT1-EC2 RT1 class Ib, locus EC2 0.010
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.010
Cckar cholecystokinin A receptor 0.010
Prl4a1 prolactin family 4, subfamily a, member 1 0.010
Vcsa1 variable coding sequence A1 0.010
Prp15 proline-rich protein 15 0.010
Rorb RAR-related orphan receptor B 0.010
Folh1 folate hydrolase 1 0.010
Zp1 zona pellucida glycoprotein 1 (sperm receptor) 0.010
Adam7 ADAM metallopeptidase domain 7 0.010
Gpr176 G protein-coupled receptor 176 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism