IMP

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Homo sapiens

2 genes annotated in human

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regulation of synaptic vesicle exocytosis

GO:2000300

Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of synaptic vesicle exocytosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of synaptic vesicle exocytosis" (in gray)

Name	Description	Probability	Func Analog Organism
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.998
LRRK2	leucine-rich repeat kinase 2	0.997
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.995
NSF	N-ethylmaleimide-sensitive factor	0.984
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.947
STX4	syntaxin 4	0.947
SNAP25	synaptosomal-associated protein, 25kDa	0.930
OCRL	oculocerebrorenal syndrome of Lowe	0.897
STX5	syntaxin 5	0.856
LRP6	low density lipoprotein receptor-related protein 6	0.796
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.712
VIM	vimentin	0.700
RAB1A	RAB1A, member RAS oncogene family	0.677
RAB5B	RAB5B, member RAS oncogene family	0.666	Human
MAP2K6	mitogen-activated protein kinase kinase 6	0.659
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.561
MAPT	microtubule-associated protein tau	0.560
GSK3B	glycogen synthase kinase 3 beta	0.550
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.529
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.510
EEA1	early endosome antigen 1	0.500
ARL8B	ADP-ribosylation factor-like 8B	0.482
NCOA3	nuclear receptor coactivator 3	0.461
DLG4	discs, large homolog 4 (Drosophila)	0.460
DCTN1	dynactin 1	0.403
RAB14	RAB14, member RAS oncogene family	0.391
MED31	mediator complex subunit 31	0.354
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.316
MAP1B	microtubule-associated protein 1B	0.295
IQGAP1	IQ motif containing GTPase activating protein 1	0.275
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.266
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.243	Fly
GDI1	GDP dissociation inhibitor 1	0.242
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.235
CLPTM1	cleft lip and palate associated transmembrane protein 1	0.216
SH3GL3	SH3-domain GRB2-like 3	0.192
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.163
ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	0.148
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.143
RAB6A	RAB6A, member RAS oncogene family	0.142
PICALM	phosphatidylinositol binding clathrin assembly protein	0.137
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.131
NIN	ninein (GSK3B interacting protein)	0.129
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.128
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.128	Mouse
PRKCE	protein kinase C, epsilon	0.122
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.122
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.121
OSBPL8	oxysterol binding protein-like 8	0.120
GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.119
TM9SF4	transmembrane 9 superfamily protein member 4	0.115
KSR1	kinase suppressor of ras 1	0.114
MAP2K1	mitogen-activated protein kinase kinase 1	0.105
SDCBP	syndecan binding protein (syntenin)	0.105
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.103
RAP1GAP	RAP1 GTPase activating protein	0.100
PEBP4	phosphatidylethanolamine-binding protein 4	0.090
ANXA7	annexin A7	0.086
MAST1	microtubule associated serine/threonine kinase 1	0.080
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.079
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.078
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.077
RAP2C	RAP2C, member of RAS oncogene family	0.075
RABAC1	Rab acceptor 1 (prenylated)	0.071
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.071
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.069
WBP2	WW domain binding protein 2	0.068
KIF5B	kinesin family member 5B	0.066
ZRANB1	zinc finger, RAN-binding domain containing 1	0.066
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.065
RAB7A	RAB7A, member RAS oncogene family	0.061
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.061
RTN4	reticulon 4	0.060
CPLX1	complexin 1	0.054
GOLGB1	golgin B1	0.051
APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.050
ADIPOR1	adiponectin receptor 1	0.050
RHEB	Ras homolog enriched in brain	0.050
REEP5	receptor accessory protein 5	0.046
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.045
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.045
HTT	huntingtin	0.044
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.043
IVNS1ABP	influenza virus NS1A binding protein	0.043
KIAA1377	KIAA1377	0.043
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.042
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.041
ARF3	ADP-ribosylation factor 3	0.040
DAPK1	death-associated protein kinase 1	0.039
DYNLT3	dynein, light chain, Tctex-type 3	0.038
BSN	bassoon (presynaptic cytomatrix protein)	0.037
CLIC4	chloride intracellular channel 4	0.036
RALGDS	ral guanine nucleotide dissociation stimulator	0.035
MAP2K3	mitogen-activated protein kinase kinase 3	0.035
BAG1	BCL2-associated athanogene	0.035
MCOLN1	mucolipin 1	0.034
KLC2	kinesin light chain 2	0.034
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.033
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.033
RNF6	ring finger protein (C3H2C3 type) 6	0.033
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.033
SYT1	synaptotagmin I	0.033
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.032
SNAP23	synaptosomal-associated protein, 23kDa	0.032
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.032
RAB5C	RAB5C, member RAS oncogene family	0.032	Human
ZFYVE20	zinc finger, FYVE domain containing 20	0.032
STXBP1	syntaxin binding protein 1	0.032	Rat
WTAP	Wilms tumor 1 associated protein	0.031
ARF6	ADP-ribosylation factor 6	0.030
CALCOCO1	calcium binding and coiled-coil domain 1	0.030
ZBTB43	zinc finger and BTB domain containing 43	0.030
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.029
ERC2	ELKS/RAB6-interacting/CAST family member 2	0.029
STX1A	syntaxin 1A (brain)	0.029	Mouse
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.028
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.028
FEM1C	fem-1 homolog c (C. elegans)	0.027
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.027
RAB5A	RAB5A, member RAS oncogene family	0.027
KIAA1191	KIAA1191	0.027
KBTBD2	kelch repeat and BTB (POZ) domain containing 2	0.027
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.026
CLIP1	CAP-GLY domain containing linker protein 1	0.026
PRRC2C	proline-rich coiled-coil 2C	0.026
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.025
CDK17	cyclin-dependent kinase 17	0.025
MED13L	mediator complex subunit 13-like	0.025
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.025
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.025
TRDMT1	tRNA aspartic acid methyltransferase 1	0.025
AKIRIN1	akirin 1	0.024
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.024
PEBP1	phosphatidylethanolamine binding protein 1	0.024
RAP1A	RAP1A, member of RAS oncogene family	0.023	Mouse
SUN2	Sad1 and UNC84 domain containing 2	0.023
RAB21	RAB21, member RAS oncogene family	0.023	Human
RAB26	RAB26, member RAS oncogene family	0.023
NECAP1	NECAP endocytosis associated 1	0.022
PTP4A1	protein tyrosine phosphatase type IVA, member 1	0.022
ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1	0.022
RNF111	ring finger protein 111	0.022
MBNL1	muscleblind-like (Drosophila)	0.022
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.022
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.021
RAB1B	RAB1B, member RAS oncogene family	0.021
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.021
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.021
STK4	serine/threonine kinase 4	0.021
CRMP1	collapsin response mediator protein 1	0.021
LRRK1	leucine-rich repeat kinase 1	0.021	Human
CEP164	centrosomal protein 164kDa	0.021
WSB1	WD repeat and SOCS box containing 1	0.021
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.020
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.020
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.020	Fly
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.019
TRIOBP	TRIO and F-actin binding protein	0.019
PRRT2	proline-rich transmembrane protein 2	0.019
NRBP1	nuclear receptor binding protein 1	0.019
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.019
NRBF2	nuclear receptor binding factor 2	0.019
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.019
NR1D2	nuclear receptor subfamily 1, group D, member 2	0.019
HAP1	huntingtin-associated protein 1	0.018
RYBP	RING1 and YY1 binding protein	0.018
ARMCX2	armadillo repeat containing, X-linked 2	0.018
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.017
ZFAND3	zinc finger, AN1-type domain 3	0.017
PPTC7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.017
SMAD7	SMAD family member 7	0.017
CLTC	clathrin, heavy chain (Hc)	0.017
HIP1	huntingtin interacting protein 1	0.017
UNC13B	unc-13 homolog B (C. elegans)	0.017	Rat
NUCB1	nucleobindin 1	0.017
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.017
SLC48A1	solute carrier family 48 (heme transporter), member 1	0.017
YAP1	Yes-associated protein 1	0.017
RIT1	Ras-like without CAAX 1	0.017
PDLIM1	PDZ and LIM domain 1	0.016
ALS2	amyotrophic lateral sclerosis 2 (juvenile)	0.016
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.016
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.016
AKAP13	A kinase (PRKA) anchor protein 13	0.016
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.016
SPOP	speckle-type POZ protein	0.016
MAP2K7	mitogen-activated protein kinase kinase 7	0.016
RIMS2	regulating synaptic membrane exocytosis 2	0.016
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.016
FGF5	fibroblast growth factor 5	0.016
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.016
CCNT1	cyclin T1	0.015
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.015
USP22	ubiquitin specific peptidase 22	0.015
TNPO1	transportin 1	0.015
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.015
RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	0.015
FAM134C	family with sequence similarity 134, member C	0.015
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.014
KDM5A	lysine (K)-specific demethylase 5A	0.014
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.014
ACBD3	acyl-CoA binding domain containing 3	0.014
TRIP10	thyroid hormone receptor interactor 10	0.014
BTBD7	BTB (POZ) domain containing 7	0.014
DPYSL4	dihydropyrimidinase-like 4	0.014
TAOK1	TAO kinase 1	0.014
SPAG9	sperm associated antigen 9	0.014
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.014
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.014
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.014
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.014
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.014
RAB3A	RAB3A, member RAS oncogene family	0.014	Mouse
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.014
ZNF267	zinc finger protein 267	0.013
CHSY1	chondroitin sulfate synthase 1	0.013
FNDC3B	fibronectin type III domain containing 3B	0.013
ATXN3	ataxin 3	0.013
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.013
KIAA1543	KIAA1543	0.013
ARHGAP21	Rho GTPase activating protein 21	0.013
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.013
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.013
PI4KB	phosphatidylinositol 4-kinase, catalytic, beta	0.013
RASA2	RAS p21 protein activator 2	0.013
CHGB	chromogranin B (secretogranin 1)	0.013
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.013
MAN2A2	mannosidase, alpha, class 2A, member 2	0.013
MAP4	microtubule-associated protein 4	0.013
PTPRS	protein tyrosine phosphatase, receptor type, S	0.013
RAI14	retinoic acid induced 14	0.013
ADRA2C	adrenergic, alpha-2C-, receptor	0.013
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
XIAP	X-linked inhibitor of apoptosis	0.012
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.012
OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	0.012
BSDC1	BSD domain containing 1	0.012
NEFL	neurofilament, light polypeptide	0.012
FAM190B	family with sequence similarity 190, member B	0.012
LYST	lysosomal trafficking regulator	0.012
AGFG1	ArfGAP with FG repeats 1	0.012
ZNF135	zinc finger protein 135	0.012
ALAS1	aminolevulinate, delta-, synthase 1	0.012
TMEM44	transmembrane protein 44	0.012
ING1	inhibitor of growth family, member 1	0.012
RAB3B	RAB3B, member RAS oncogene family	0.012
FABP4	fatty acid binding protein 4, adipocyte	0.012
ITSN1	intersectin 1 (SH3 domain protein)	0.012
SYN2	synapsin II	0.012
PIM2	pim-2 oncogene	0.012
ZBTB45	zinc finger and BTB domain containing 45	0.012
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.012
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.012
CELF4	CUGBP, Elav-like family member 4	0.012
CPLX2	complexin 2	0.012
MARK1	MAP/microtubule affinity-regulating kinase 1	0.012
RHBDD2	rhomboid domain containing 2	0.011
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.011
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.011
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.011
NRXN1	neurexin 1	0.011
TPPP	tubulin polymerization promoting protein	0.011
TRAFD1	TRAF-type zinc finger domain containing 1	0.011
PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	0.011
GJA5	gap junction protein, alpha 5, 40kDa	0.011
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.011
NPTX1	neuronal pentraxin I	0.011
DOCK3	dedicator of cytokinesis 3	0.011
OXSR1	oxidative-stress responsive 1	0.011
RAB7L1	RAB7, member RAS oncogene family-like 1	0.011
RIMS1	regulating synaptic membrane exocytosis 1	0.011	Rat
MEF2D	myocyte enhancer factor 2D	0.011
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.011
ANKRD11	ankyrin repeat domain 11	0.011
HMBOX1	homeobox containing 1	0.011
RAB4B	RAB4B, member RAS oncogene family	0.011
RAB3C	RAB3C, member RAS oncogene family	0.011
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.011
MYO1D	myosin ID	0.011
CLDND1	claudin domain containing 1	0.011
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	0.011
RAB6C	RAB6C, member RAS oncogene family	0.011
PTP4A2	protein tyrosine phosphatase type IVA, member 2	0.011
BAHD1	bromo adjacent homology domain containing 1	0.011
CCDC88A	coiled-coil domain containing 88A	0.011
MARCH5	membrane-associated ring finger (C3HC4) 5	0.011
PCSK2	proprotein convertase subtilisin/kexin type 2	0.011
MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)	0.010
ACSL4	acyl-CoA synthetase long-chain family member 4	0.010
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.010
PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2	0.010
CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	0.010
N4BP1	NEDD4 binding protein 1	0.010
DSTYK	dual serine/threonine and tyrosine protein kinase	0.010
TCHP	trichoplein, keratin filament binding	0.010
RIPK3	receptor-interacting serine-threonine kinase 3	0.010
RRAS2	related RAS viral (r-ras) oncogene homolog 2	0.010
JAK1	Janus kinase 1	0.010
SYNGR3	synaptogyrin 3	0.010
ZBTB38	zinc finger and BTB domain containing 38	0.010
PDK2	pyruvate dehydrogenase kinase, isozyme 2	0.010
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.010
SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	0.010
CACNB4	calcium channel, voltage-dependent, beta 4 subunit	0.010
EGR2	early growth response 2	0.010
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.010
SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	0.010
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.010
TUSC3	tumor suppressor candidate 3	0.010
SELENBP1	selenium binding protein 1	0.010
PTPRO	protein tyrosine phosphatase, receptor type, O	0.010
DIS3L2	DIS3 mitotic control homolog (S. cerevisiae)-like 2	0.010
ZNF264	zinc finger protein 264	0.010
ELF1	E74-like factor 1 (ets domain transcription factor)	0.010
TRADD	TNFRSF1A-associated via death domain	0.010
VPS39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.010
RGS2	regulator of G-protein signaling 2, 24kDa	0.010