IMP

Process View

Homo sapiens

18 genes annotated in human

regulation of tyrosine phosphorylation of stat3 protein

Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat3 protein.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of tyrosine phosphorylation of stat3 protein"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of tyrosine phosphorylation of stat3 protein" (in gray)

Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000
GHR	growth hormone receptor	0.999
EGFR	epidermal growth factor receptor	0.999
JAK2	Janus kinase 2	0.999	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.998
SOCS3	suppressor of cytokine signaling 3	0.996
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.992
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.992
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.991	Human
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.990
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.947
LAT	linker for activation of T cells	0.914
GH1	growth hormone 1	0.884
JAK1	Janus kinase 1	0.864
PTPRB	protein tyrosine phosphatase, receptor type, B	0.847
INSR	insulin receptor	0.831
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.819	Human
HDAC2	histone deacetylase 2	0.751
VEGFA	vascular endothelial growth factor A	0.734
IL23A	interleukin 23, alpha subunit p19	0.688
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.658
IL6R	interleukin 6 receptor	0.615
CD44	CD44 molecule (Indian blood group)	0.571
GAB1	GRB2-associated binding protein 1	0.552
IL6	interleukin 6 (interferon, beta 2)	0.538
IRS1	insulin receptor substrate 1	0.507
CSH2	chorionic somatomammotropin hormone 2	0.437	Human
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.407
SOCS1	suppressor of cytokine signaling 1	0.403	Mouse
STAT1	signal transducer and activator of transcription 1, 91kDa	0.376
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.336	Human
CSHL1	chorionic somatomammotropin hormone-like 1	0.308	Human
NRP1	neuropilin 1	0.291
IGF1R	insulin-like growth factor 1 receptor	0.286
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.284	Human
GH2	growth hormone 2	0.282	Human
GRB2	growth factor receptor-bound protein 2	0.280
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.240
IL22	interleukin 22	0.239
SCHIP1	schwannomin interacting protein 1	0.229
PLCG1	phospholipase C, gamma 1	0.210
TBC1D10A	TBC1 domain family, member 10A	0.199
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.188
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.187
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.164
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.147
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.126
CNTF	ciliary neurotrophic factor	0.111
EPOR	erythropoietin receptor	0.087
CAV1	caveolin 1, caveolae protein, 22kDa	0.082
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.082
SH2B1	SH2B adaptor protein 1	0.081
PGF	placental growth factor	0.078
STAT4	signal transducer and activator of transcription 4	0.075
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.073
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.073	Human
FRS2	fibroblast growth factor receptor substrate 2	0.069
CAPN1	calpain 1, (mu/I) large subunit	0.062
CDH5	cadherin 5, type 2 (vascular endothelium)	0.060
EZR	ezrin	0.058	Human
GRB7	growth factor receptor-bound protein 7	0.057
JAK3	Janus kinase 3	0.056
KITLG	KIT ligand	0.052
CD33	CD33 molecule	0.051
MED28	mediator complex subunit 28	0.049
SOCS2	suppressor of cytokine signaling 2	0.048
GAB2	GRB2-associated binding protein 2	0.048
ICAM1	intercellular adhesion molecule 1	0.048
IFNGR1	interferon gamma receptor 1	0.048
PTK2	PTK2 protein tyrosine kinase 2	0.047
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.047
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.046
FGF10	fibroblast growth factor 10	0.046
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.046
STAT5A	signal transducer and activator of transcription 5A	0.044
BCAR1	breast cancer anti-estrogen resistance 1	0.042
PDGFA	platelet-derived growth factor alpha polypeptide	0.042
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.041
SYK	spleen tyrosine kinase	0.041
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.040
ICA1	islet cell autoantigen 1, 69kDa	0.039
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.038
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.036
SNAI1	snail homolog 1 (Drosophila)	0.033
FGFR1	fibroblast growth factor receptor 1	0.033	Human
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.033
LIFR	leukemia inhibitory factor receptor alpha	0.032	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.031
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.031
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.030
SOS2	son of sevenless homolog 2 (Drosophila)	0.029
EXT1	exostosin 1	0.028
TLR3	toll-like receptor 3	0.027
SLA	Src-like-adaptor	0.026
STC1	stanniocalcin 1	0.026
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.024
GRB10	growth factor receptor-bound protein 10	0.024
CMIP	c-Maf-inducing protein	0.023
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.022	Human
PDGFC	platelet derived growth factor C	0.022
STAT5B	signal transducer and activator of transcription 5B	0.022
OSM	oncostatin M	0.021
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.021
CD28	CD28 molecule	0.021
CXCL2	chemokine (C-X-C motif) ligand 2	0.019
SOS1	son of sevenless homolog 1 (Drosophila)	0.019
COMMD1	copper metabolism (Murr1) domain containing 1	0.019
HSPG2	heparan sulfate proteoglycan 2	0.018
LDLR	low density lipoprotein receptor	0.018
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.017
ITGA1	integrin, alpha 1	0.016
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.016
IL10	interleukin 10	0.016
NSF	N-ethylmaleimide-sensitive factor	0.015
BBS10	Bardet-Biedl syndrome 10	0.015
IFNA10	interferon, alpha 10	0.015	Human
FGF2	fibroblast growth factor 2 (basic)	0.015
AXL	AXL receptor tyrosine kinase	0.015
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.015
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.014	Human
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.014
PTEN	phosphatase and tensin homolog	0.014
ADRB2	adrenergic, beta-2-, receptor, surface	0.013
KRT8	keratin 8	0.013
OSMR	oncostatin M receptor	0.013	Human
THBS1	thrombospondin 1	0.012
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.012
CSF1	colony stimulating factor 1 (macrophage)	0.012
MPZL1	myelin protein zero-like 1	0.012
CSNK1E	casein kinase 1, epsilon	0.012
VHL	von Hippel-Lindau tumor suppressor	0.012
IL12RB2	interleukin 12 receptor, beta 2	0.012	Human
FLT4	fms-related tyrosine kinase 4	0.012	Human
ZNF331	zinc finger protein 331	0.011
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.011
IFNA4	interferon, alpha 4	0.011
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.011
IRS2	insulin receptor substrate 2	0.011
HRH1	histamine receptor H1	0.011
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.011
SELPLG	selectin P ligand	0.010
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.010
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.010
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.010