IMP

Process View

Homo sapiens

23 genes annotated in human

interferon beta production

The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "interferon beta production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "interferon beta production" (in gray)

Name	Description	Probability	Func Analog Organism
CYLD	cylindromatosis (turban tumor syndrome)	0.940
PILRA	paired immunoglobin-like type 2 receptor alpha	0.901
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.865
STAT2	signal transducer and activator of transcription 2, 113kDa	0.834
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.833
PIAS4	protein inhibitor of activated STAT, 4	0.735
MAVS	mitochondrial antiviral signaling protein	0.624
TICAM2	toll-like receptor adaptor molecule 2	0.617
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.576
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.574	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.570
MYD88	myeloid differentiation primary response gene (88)	0.553
STAT1	signal transducer and activator of transcription 1, 91kDa	0.503
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.481	Human
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.466	Human
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.421	Human
IRF3	interferon regulatory factor 3	0.286	Human Mouse
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.239
IRF7	interferon regulatory factor 7	0.212	Human Mouse
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.196	Human
TBK1	TANK-binding kinase 1	0.189
TRAF3	TNF receptor-associated factor 3	0.164	Mouse
NLRC4	NLR family, CARD domain containing 4	0.155
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.150
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.142
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.129
RANBP3	RAN binding protein 3	0.125
PTAFR	platelet-activating factor receptor	0.125
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.114
MEFV	Mediterranean fever	0.099
IRF1	interferon regulatory factor 1	0.096
CD86	CD86 molecule	0.094
HK3	hexokinase 3 (white cell)	0.092
SIGLEC7	sialic acid binding Ig-like lectin 7	0.089
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.087
NLRP3	NLR family, pyrin domain containing 3	0.083
ISG15	ISG15 ubiquitin-like modifier	0.077
AZI2	5-azacytidine induced 2	0.074
TRAF2	TNF receptor-associated factor 2	0.071
KAT2B	K(lysine) acetyltransferase 2B	0.069
CCR1	chemokine (C-C motif) receptor 1	0.065
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.064
LY86	lymphocyte antigen 86	0.051
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.050
CREBBP	CREB binding protein	0.049
IRAK1	interleukin-1 receptor-associated kinase 1	0.049
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.046
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.045
USP18	ubiquitin specific peptidase 18	0.045
IRF9	interferon regulatory factor 9	0.041	Human
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.039
TRIM25	tripartite motif containing 25	0.036
TANK	TRAF family member-associated NFKB activator	0.036
CD180	CD180 molecule	0.033	Human
ZNFX1	zinc finger, NFX1-type containing 1	0.033
POLR3H	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	0.033
CYBB	cytochrome b-245, beta polypeptide	0.033
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.033
NLRC5	NLR family, CARD domain containing 5	0.032
BIRC3	baculoviral IAP repeat containing 3	0.032
TRIM21	tripartite motif containing 21	0.032
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.032
SIRPB1	signal-regulatory protein beta 1	0.031
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.030
CD33	CD33 molecule	0.029
IRAK4	interleukin-1 receptor-associated kinase 4	0.028
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.028
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.028
TYMP	thymidine phosphorylase	0.027
PARP12	poly (ADP-ribose) polymerase family, member 12	0.027	Human
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.027
CD300C	CD300c molecule	0.026
AOAH	acyloxyacyl hydrolase (neutrophil)	0.026
IGSF6	immunoglobulin superfamily, member 6	0.026
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.026
OASL	2'-5'-oligoadenylate synthetase-like	0.026
TLR1	toll-like receptor 1	0.026	Human
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.026
IFIH1	interferon induced with helicase C domain 1	0.025
CALCOCO2	calcium binding and coiled-coil domain 2	0.025
CYTH4	cytohesin 4	0.025
ADAR	adenosine deaminase, RNA-specific	0.024
CD163	CD163 molecule	0.023
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.023
IRF8	interferon regulatory factor 8	0.023	Human
CLPX	ClpX caseinolytic peptidase X homolog (E. coli)	0.023
BTK	Bruton agammaglobulinemia tyrosine kinase	0.023
POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	0.022
VNN2	vanin 2	0.022
FKBP5	FK506 binding protein 5	0.022
SAMD9	sterile alpha motif domain containing 9	0.021
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.021
CDK9	cyclin-dependent kinase 9	0.021
BIN2	bridging integrator 2	0.021
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.020
CD28	CD28 molecule	0.020
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.020
CHUK	conserved helix-loop-helix ubiquitous kinase	0.020	Human
CMKLR1	chemokine-like receptor 1	0.019
NOD2	nucleotide-binding oligomerization domain containing 2	0.019
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.018	Human
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.018	Human
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	0.018
FPR2	formyl peptide receptor 2	0.017
LY96	lymphocyte antigen 96	0.017
SIGLEC9	sialic acid binding Ig-like lectin 9	0.017
GTF3C4	general transcription factor IIIC, polypeptide 4, 90kDa	0.017
IL15RA	interleukin 15 receptor, alpha	0.017
CSK	c-src tyrosine kinase	0.017
IFI35	interferon-induced protein 35	0.016
HERC5	hect domain and RLD 5	0.016
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.016
S100A12	S100 calcium binding protein A12	0.016
VSIG4	V-set and immunoglobulin domain containing 4	0.016
TLR6	toll-like receptor 6	0.016	Human
UBA7	ubiquitin-like modifier activating enzyme 7	0.016
BATF	basic leucine zipper transcription factor, ATF-like	0.016
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.015
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.015
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.015
TREM1	triggering receptor expressed on myeloid cells 1	0.015
TNRC6A	trinucleotide repeat containing 6A	0.015
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.015
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.015
SLAMF7	SLAM family member 7	0.015
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.015
CMIP	c-Maf-inducing protein	0.015
TLR8	toll-like receptor 8	0.014
UNC93B1	unc-93 homolog B1 (C. elegans)	0.014
MARCO	macrophage receptor with collagenous structure	0.014
C19orf66	chromosome 19 open reading frame 66	0.014
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	0.014
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
AIM2	absent in melanoma 2	0.014
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.014
ADAP2	ArfGAP with dual PH domains 2	0.014
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.014
TFEC	transcription factor EC	0.014
IRF5	interferon regulatory factor 5	0.014	Human
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.013
STAP2	signal transducing adaptor family member 2	0.013
NCOA3	nuclear receptor coactivator 3	0.013
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.013
TNRC6C	trinucleotide repeat containing 6C	0.013
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.013
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.013
TLR2	toll-like receptor 2	0.013
CD1D	CD1d molecule	0.013
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.012
IRF2	interferon regulatory factor 2	0.012	Human
SLC15A3	solute carrier family 15, member 3	0.012
PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285	0.012
TARBP2	TAR (HIV-1) RNA binding protein 2	0.012
TMEM140	transmembrane protein 140	0.012
KIAA1274	KIAA1274	0.012
C5orf56	chromosome 5 open reading frame 56	0.012
ISG20	interferon stimulated exonuclease gene 20kDa	0.012
RNASE6	ribonuclease, RNase A family, k6	0.012
GPN1	GPN-loop GTPase 1	0.012
MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)	0.012
CCR2	chemokine (C-C motif) receptor 2	0.012
TLR7	toll-like receptor 7	0.012
POLR3F	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	0.012
C13orf18	chromosome 13 open reading frame 18	0.012
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.012
PRDM1	PR domain containing 1, with ZNF domain	0.012
ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	0.012
HCK	hemopoietic cell kinase	0.011
CD300A	CD300a molecule	0.011
TNIP1	TNFAIP3 interacting protein 1	0.011
C3AR1	complement component 3a receptor 1	0.011
RNF115	ring finger protein 115	0.011
TDRD7	tudor domain containing 7	0.011
CD1C	CD1c molecule	0.011
TBKBP1	TBK1 binding protein 1	0.011
PLEK	pleckstrin	0.011
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.011
FOXO3	forkhead box O3	0.011
BAX	BCL2-associated X protein	0.011
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.011
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.011
PRKD2	protein kinase D2	0.011
MARCH1	membrane-associated ring finger (C3HC4) 1	0.011
IPO8	importin 8	0.010
DPEP2	dipeptidase 2	0.010
APOL6	apolipoprotein L, 6	0.010
DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.010	Human
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.010
AIF1	allograft inflammatory factor 1	0.010
DTX3L	deltex 3-like (Drosophila)	0.010
RPP40	ribonuclease P/MRP 40kDa subunit	0.010
FCAR	Fc fragment of IgA, receptor for	0.010	Human
CXorf21	chromosome X open reading frame 21	0.010
CLEC5A	C-type lectin domain family 5, member A	0.010