IMP

Process View

Mus musculus

1 genes annotated in mouse

positive regulation of neutrophil mediated killing of symbiont cell

Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of neutrophil mediated killing of symbiont cell"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of neutrophil mediated killing of symbiont cell" (in gray)

Name	Description	Probability	Func Analog Organism
Cxcl2	chemokine (C-X-C motif) ligand 2	0.996	Mouse
Il1rn	interleukin 1 receptor antagonist	0.983
Ccl2	chemokine (C-C motif) ligand 2	0.950
Il1b	interleukin 1 beta	0.924
Ccl7	chemokine (C-C motif) ligand 7	0.894
Cxcl1	chemokine (C-X-C motif) ligand 1	0.876
Clec4d	C-type lectin domain family 4, member d	0.872
Saa3	serum amyloid A 3	0.794
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.772
Ccl12	chemokine (C-C motif) ligand 12	0.700
Irg1	immunoresponsive gene 1	0.678
Ccl3	chemokine (C-C motif) ligand 3	0.644
Ccl8	chemokine (C-C motif) ligand 8	0.631
Slfn4	schlafen 4	0.530
Il6	interleukin 6	0.520
Ch25h	cholesterol 25-hydroxylase	0.485
Cd14	CD14 antigen	0.473
Clec4e	C-type lectin domain family 4, member e	0.447
Ccr1	chemokine (C-C motif) receptor 1	0.447
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.349
Mmp13	matrix metallopeptidase 13	0.338
Fpr2	formyl peptide receptor 2	0.335
Cxcl5	chemokine (C-X-C motif) ligand 5	0.328	Mouse
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.323
Plaur	plasminogen activator, urokinase receptor	0.318
Cxcl10	chemokine (C-X-C motif) ligand 10	0.306	Mouse
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.296
Atf3	activating transcription factor 3	0.273
Selp	selectin, platelet	0.265
Slpi	secretory leukocyte peptidase inhibitor	0.261
Msr1	macrophage scavenger receptor 1	0.236
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.188
Il1a	interleukin 1 alpha	0.167
Serpinb2	serine (or cysteine) peptidase inhibitor, clade B, member 2	0.159
Chi3l3	chitinase 3-like 3	0.150
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.149
Iigp1	interferon inducible GTPase 1	0.128
Mmp12	matrix metallopeptidase 12	0.127
Niacr1	niacin receptor 1	0.127
Lcn2	lipocalin 2	0.125
Bcl3	B-cell leukemia/lymphoma 3	0.117
Il1r2	interleukin 1 receptor, type II	0.114
Ptgs2	prostaglandin-endoperoxide synthase 2	0.113
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.105
Fcgr1	Fc receptor, IgG, high affinity I	0.103
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.097
Adam8	a disintegrin and metallopeptidase domain 8	0.095
Rsad2	radical S-adenosyl methionine domain containing 2	0.094
Isg15	ISG15 ubiquitin-like modifier	0.092
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.089
Slfn1	schlafen 1	0.088
Ccl4	chemokine (C-C motif) ligand 4	0.087
Il18rap	interleukin 18 receptor accessory protein	0.086
Mmp8	matrix metallopeptidase 8	0.073
C3ar1	complement component 3a receptor 1	0.065
Cd86	CD86 antigen	0.062
Junb	Jun-B oncogene	0.061
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.051
Gbp1	guanylate binding protein 1	0.048
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.047
Hmox1	heme oxygenase (decycling) 1	0.046
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.046
Ccr5	chemokine (C-C motif) receptor 5	0.045
Igsf6	immunoglobulin superfamily, member 6	0.044
Socs3	suppressor of cytokine signaling 3	0.043
Ereg	epiregulin	0.042
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.042
Nlrp3	NLR family, pyrin domain containing 3	0.041
Il1rl1	interleukin 1 receptor-like 1	0.041
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.040
Mx2	myxovirus (influenza virus) resistance 2	0.038
Bst1	bone marrow stromal cell antigen 1	0.037
Mmp3	matrix metallopeptidase 3	0.036
Hp	haptoglobin	0.036
Areg	amphiregulin	0.036
Ifng	interferon gamma	0.035
Ccrl2	chemokine (C-C motif) receptor-like 2	0.034
Fpr1	formyl peptide receptor 1	0.034
Timp1	tissue inhibitor of metalloproteinase 1	0.033
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.032
Fosl1	fos-like antigen 1	0.031
Egr2	early growth response 2	0.030
Sele	selectin, endothelial cell	0.030
Ifi47	interferon gamma inducible protein 47	0.030
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.030
Fos	FBJ osteosarcoma oncogene	0.029
Ccl5	chemokine (C-C motif) ligand 5	0.028
Mx1	myxovirus (influenza virus) resistance 1	0.028
Gzma	granzyme A	0.028
Ier3	immediate early response 3	0.027
Tlr2	toll-like receptor 2	0.026
Osmr	oncostatin M receptor	0.026
Cxcl3	chemokine (C-X-C motif) ligand 3	0.026
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.025
Tnf	tumor necrosis factor	0.025
Ppbp	pro-platelet basic protein	0.025
Icam1	intercellular adhesion molecule 1	0.024
Ubd	ubiquitin D	0.024
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.024
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.023
Zfp36	zinc finger protein 36	0.022
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.022
Gbp2	guanylate binding protein 2	0.022
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.021
Rgs1	regulator of G-protein signaling 1	0.021
Gbp3	guanylate binding protein 3	0.021
Cd80	CD80 antigen	0.021
Igtp	interferon gamma induced GTPase	0.021
Akr1b8	aldo-keto reductase family 1, member B8	0.020
Irf7	interferon regulatory factor 7	0.020
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.020
Gpr35	G protein-coupled receptor 35	0.020
Tgtp2	T-cell specific GTPase 2	0.019
Il18r1	interleukin 18 receptor 1	0.018
F13a1	coagulation factor XIII, A1 subunit	0.018
Clec7a	C-type lectin domain family 7, member a	0.018
Ifih1	interferon induced with helicase C domain 1	0.018
Ccr2	chemokine (C-C motif) receptor 2	0.018
Usp18	ubiquitin specific peptidase 18	0.018
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.018
Nfe2	nuclear factor, erythroid derived 2	0.017
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.017
Ptgir	prostaglandin I receptor (IP)	0.017
Fgl2	fibrinogen-like protein 2	0.017
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.017
Cytip	cytohesin 1 interacting protein	0.017
F10	coagulation factor X	0.017
Ccl6	chemokine (C-C motif) ligand 6	0.016
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.016
Ldlr	low density lipoprotein receptor	0.016
Ifi44	interferon-induced protein 44	0.016
Fcgr4	Fc receptor, IgG, low affinity IV	0.016
Chi3l1	chitinase 3-like 1	0.016
Rgs16	regulator of G-protein signaling 16	0.016
Vcam1	vascular cell adhesion molecule 1	0.016
Gm6377	predicted gene 6377	0.016
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.015
Igj	immunoglobulin joining chain	0.015
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.015
Tgm2	transglutaminase 2, C polypeptide	0.015
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.015
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.015
Prdm1	PR domain containing 1, with ZNF domain	0.014
Cdcp1	CUB domain containing protein 1	0.014
Slc15a3	solute carrier family 15, member 3	0.014
Cd40	CD40 antigen	0.014
Upp1	uridine phosphorylase 1	0.014
Procr	protein C receptor, endothelial	0.013
Clec4n	C-type lectin domain family 4, member n	0.013
Fabp4	fatty acid binding protein 4, adipocyte	0.013
Tfpi2	tissue factor pathway inhibitor 2	0.013
Cd300lf	CD300 antigen like family member F	0.013
Cdh1	cadherin 1	0.013
Il18bp	interleukin 18 binding protein	0.013
Ifitm6	interferon induced transmembrane protein 6	0.012
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.012
Slamf8	SLAM family member 8	0.012
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.012
Fcgr3	Fc receptor, IgG, low affinity III	0.012
Gzmb	granzyme B	0.012
Folr2	folate receptor 2 (fetal)	0.012
Ccl17	chemokine (C-C motif) ligand 17	0.012
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.012
Cxcl16	chemokine (C-X-C motif) ligand 16	0.012
AI607873	expressed sequence AI607873	0.011
C2	complement component 2 (within H-2S)	0.011
Isg20	interferon-stimulated protein	0.011
Has2	hyaluronan synthase 2	0.011
Ifi202b	interferon activated gene 202B	0.011
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.011
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.011
Birc3	baculoviral IAP repeat-containing 3	0.011
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.011
Ccl9	chemokine (C-C motif) ligand 9	0.011
Ccl22	chemokine (C-C motif) ligand 22	0.011
Tspan8	tetraspanin 8	0.011
Ptges	prostaglandin E synthase	0.010
Cpa3	carboxypeptidase A3, mast cell	0.010
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.010
Rel	reticuloendotheliosis oncogene	0.010
Hbegf	heparin-binding EGF-like growth factor	0.010
Car13	carbonic anhydrase 13	0.010
Plscr1	phospholipid scramblase 1	0.010