IMP

Process View

Mus musculus

11 genes annotated in mouse

response to x ray

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to x ray"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to x ray" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Atm	ataxia telangiectasia mutated homolog (human)	0.988
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.976
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.934
Stat5a	signal transducer and activator of transcription 5A	0.915	Fly
Notch2	Notch gene homolog 2 (Drosophila)	0.872
Mdm4	transformed mouse 3T3 cell double minute 4	0.826
Brca1	breast cancer 1	0.816
Stat5b	signal transducer and activator of transcription 5B	0.667	Fly
Kit	kit oncogene	0.656
Sfrp2	secreted frizzled-related protein 2	0.602
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.568
Mdm2	transformed mouse 3T3 cell double minute 2	0.489	Zebrafish
Thbs1	thrombospondin 1	0.446
Sfrp1	secreted frizzled-related protein 1	0.398
Nos3	nitric oxide synthase 3, endothelial cell	0.394
Smc3	structural maintenace of chromosomes 3	0.340
Rb1	retinoblastoma 1	0.330
Msh2	mutS homolog 2 (E. coli)	0.320
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.315
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.301
Apc	adenomatosis polyposis coli	0.263
Flt4	FMS-like tyrosine kinase 4	0.246
Mcl1	myeloid cell leukemia sequence 1	0.207
Nbn	nibrin	0.189
Ahr	aryl-hydrocarbon receptor	0.189
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.181
Xpa	xeroderma pigmentosum, complementation group A	0.175
Vhl	von Hippel-Lindau tumor suppressor	0.174
Foxp3	forkhead box P3	0.163
Brca2	breast cancer 2	0.147
Stat3	signal transducer and activator of transcription 3	0.110
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.089
Cdk4	cyclin-dependent kinase 4	0.088
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.087
Kdr	kinase insert domain protein receptor	0.087
Pten	phosphatase and tensin homolog	0.079
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.078
Cdk6	cyclin-dependent kinase 6	0.070
Stk11	serine/threonine kinase 11	0.065
Adam17	a disintegrin and metallopeptidase domain 17	0.062
Egln1	EGL nine homolog 1 (C. elegans)	0.060
Smad4	MAD homolog 4 (Drosophila)	0.059
Il4ra	interleukin 4 receptor, alpha	0.059
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.059
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.055
Pdgfc	platelet-derived growth factor, C polypeptide	0.055
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.052
Mlh1	mutL homolog 1 (E. coli)	0.047
Rara	retinoic acid receptor, alpha	0.042
Vangl2	vang-like 2 (van gogh, Drosophila)	0.042
Ar	androgen receptor	0.042
Esr1	estrogen receptor 1 (alpha)	0.042
Mybl2	myeloblastosis oncogene-like 2	0.038
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.037
Skil	SKI-like	0.036
Epas1	endothelial PAS domain protein 1	0.034
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.034
Tgfb1	transforming growth factor, beta 1	0.034
Huwe1	HECT, UBA and WWE domain containing 1	0.033
F2r	coagulation factor II (thrombin) receptor	0.033
Wnt5a	wingless-related MMTV integration site 5A	0.032
Dll1	delta-like 1 (Drosophila)	0.032
Efnb2	ephrin B2	0.032
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.032
Itga3	integrin alpha 3	0.031
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.031
Yap1	yes-associated protein 1	0.030
Wrn	Werner syndrome homolog (human)	0.030
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.029
Casp3	caspase 3	0.026
Braf	Braf transforming gene	0.026
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.025
Nf2	neurofibromatosis 2	0.024
Ptgs2	prostaglandin-endoperoxide synthase 2	0.024
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.024
Sgpl1	sphingosine phosphate lyase 1	0.023
Chd2	chromodomain helicase DNA binding protein 2	0.022
Ep300	E1A binding protein p300	0.022
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.022
Hr	hairless	0.022
Sox4	SRY-box containing gene 4	0.021
Mecp2	methyl CpG binding protein 2	0.021
Terf1	telomeric repeat binding factor 1	0.021
Fzd4	frizzled homolog 4 (Drosophila)	0.020
Fas	Fas (TNF receptor superfamily member 6)	0.020
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.020
Wwox	WW domain-containing oxidoreductase	0.019	Fly
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.019
S1pr2	sphingosine-1-phosphate receptor 2	0.018
Smn1	survival motor neuron 1	0.018
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.017
Flt1	FMS-like tyrosine kinase 1	0.017
Sfn	stratifin	0.017
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.017
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.016
Runx1	runt related transcription factor 1	0.016
Men1	multiple endocrine neoplasia 1	0.016
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.016
Atr	ataxia telangiectasia and Rad3 related	0.016
Hbegf	heparin-binding EGF-like growth factor	0.016
Cdk2	cyclin-dependent kinase 2	0.015
Daxx	Fas death domain-associated protein	0.015
Atad5	ATPase family, AAA domain containing 5	0.015
Klf4	Kruppel-like factor 4 (gut)	0.015
Gaa	glucosidase, alpha, acid	0.014
Ndn	necdin	0.014
Sox18	SRY-box containing gene 18	0.014
Notch1	Notch gene homolog 1 (Drosophila)	0.014
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.014
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.014
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.014
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.014
Rxra	retinoid X receptor alpha	0.013
Sltm	SAFB-like, transcription modulator	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Twist1	twist homolog 1 (Drosophila)	0.013
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.013
Fbln1	fibulin 1	0.013
Mphosph9	M-phase phosphoprotein 9	0.013
Smad3	MAD homolog 3 (Drosophila)	0.012
Krit1	KRIT1, ankyrin repeat containing	0.012
Mycbp2	MYC binding protein 2	0.012
Rbl1	retinoblastoma-like 1 (p107)	0.012
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
Bard1	BRCA1 associated RING domain 1	0.011
Adora2a	adenosine A2a receptor	0.011
Mapk14	mitogen-activated protein kinase 14	0.011
Dmtf1	cyclin D binding myb-like transcription factor 1	0.011
Rc3h1	RING CCCH (C3H) domains 1	0.011
Tsc1	tuberous sclerosis 1	0.011
Rttn	rotatin	0.011
Efs	embryonal Fyn-associated substrate	0.011
Mmp9	matrix metallopeptidase 9	0.011
Spna1	spectrin alpha 1	0.011
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.010
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.010
Tlr4	toll-like receptor 4	0.010