IMP

Process View

Mus musculus

10 genes annotated in mouse

regulation of triglyceride biosynthetic process

Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of triglyceride biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of triglyceride biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Apoe	apolipoprotein E	0.984
Dab1	disabled homolog 1 (Drosophila)	0.894
Lef1	lymphoid enhancer binding factor 1	0.683	Mouse
Ghr	growth hormone receptor	0.643
Tcf7	transcription factor 7, T-cell specific	0.556	Mouse
Irs2	insulin receptor substrate 2	0.528
Scd1	stearoyl-Coenzyme A desaturase 1	0.527
Abhd5	abhydrolase domain containing 5	0.492
Pparg	peroxisome proliferator activated receptor gamma	0.481
Pnpla2	patatin-like phospholipase domain containing 2	0.433
Cav1	caveolin 1, caveolae protein	0.260
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.209
Npc1	Niemann Pick type C1	0.181
Srf	serum response factor	0.154
Esr1	estrogen receptor 1 (alpha)	0.143
Lrp1	low density lipoprotein receptor-related protein 1	0.137
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.134
Lepr	leptin receptor	0.115
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.111
Fasn	fatty acid synthase	0.106
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.100
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.093
Nos3	nitric oxide synthase 3, endothelial cell	0.089
Cyp51	cytochrome P450, family 51	0.074
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.072
Psen1	presenilin 1	0.068
Reln	reelin	0.065
Adipoq	adiponectin, C1Q and collagen domain containing	0.065
Dhcr7	7-dehydrocholesterol reductase	0.064
Vldlr	very low density lipoprotein receptor	0.064	Mouse
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.063	Human
Lep	leptin	0.062
Ahr	aryl-hydrocarbon receptor	0.060
Ar	androgen receptor	0.060
Adipor2	adiponectin receptor 2	0.057
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.057	Mouse
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.054
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.050
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.047
Lss	lanosterol synthase	0.045
Kiss1	KiSS-1 metastasis-suppressor	0.045
Irs1	insulin receptor substrate 1	0.044
Insr	insulin receptor	0.043
Notch1	Notch gene homolog 1 (Drosophila)	0.043
Lpin1	lipin 1	0.042
Apoc1	apolipoprotein C-I	0.041
Kit	kit oncogene	0.038
Tlr2	toll-like receptor 2	0.037
Thra	thyroid hormone receptor alpha	0.037
Fabp4	fatty acid binding protein 4, adipocyte	0.037
Dhcr24	24-dehydrocholesterol reductase	0.036
Cidec	cell death-inducing DFFA-like effector c	0.036
Slc12a6	solute carrier family 12, member 6	0.036
Pten	phosphatase and tensin homolog	0.035
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.035
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.030
Lcat	lecithin cholesterol acyltransferase	0.030
Epn1	epsin 1	0.028
Sqle	squalene epoxidase	0.028
G0s2	G0/G1 switch gene 2	0.028
Ncoa3	nuclear receptor coactivator 3	0.027
Notch2	Notch gene homolog 2 (Drosophila)	0.026
Gjb2	gap junction protein, beta 2	0.026
Cfd	complement factor D (adipsin)	0.025
Ldlr	low density lipoprotein receptor	0.025
Gsk3b	glycogen synthase kinase 3 beta	0.025
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.025
Lrp5	low density lipoprotein receptor-related protein 5	0.025
Pcx	pyruvate carboxylase	0.024
Prlr	prolactin receptor	0.024
Tbx3	T-box 3	0.024
Cd36	CD36 antigen	0.024	Mouse
Pvrl2	poliovirus receptor-related 2	0.023
Axin2	axin2	0.023
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.022
Rxra	retinoid X receptor alpha	0.022
Pias4	protein inhibitor of activated STAT 4	0.022
Igf1	insulin-like growth factor 1	0.022
Por	P450 (cytochrome) oxidoreductase	0.021
Klf15	Kruppel-like factor 15	0.021
Fas	Fas (TNF receptor superfamily member 6)	0.021
Il1r1	interleukin 1 receptor, type I	0.021
Ppap2b	phosphatidic acid phosphatase type 2B	0.021
Otx2	orthodenticle homolog 2 (Drosophila)	0.021
Ptk2	PTK2 protein tyrosine kinase 2	0.021
Nos1	nitric oxide synthase 1, neuronal	0.021
Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)	0.020
Aacs	acetoacetyl-CoA synthetase	0.019
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.019
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.019
Clock	circadian locomotor output cycles kaput	0.019
Actn4	actinin alpha 4	0.018
Lipe	lipase, hormone sensitive	0.018
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.018
Dll1	delta-like 1 (Drosophila)	0.018
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.018	Human
Agtr1a	angiotensin II receptor, type 1a	0.018
Fads2	fatty acid desaturase 2	0.018
Amy1	amylase 1, salivary	0.018
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.018
Trim8	tripartite motif-containing 8	0.018
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.018
Sept5	septin 5	0.018
Gsta3	glutathione S-transferase, alpha 3	0.017
Acly	ATP citrate lyase	0.017
Car3	carbonic anhydrase 3	0.017
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.017
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.017
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.016
Foxo1	forkhead box O1	0.016
Hmg20b	high mobility group 20 B	0.016
Gata3	GATA binding protein 3	0.016
Nrg4	neuregulin 4	0.016
Id3	inhibitor of DNA binding 3	0.016
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.016
Plin4	perilipin 4	0.016
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.016
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.016
1500002O20Rik	RIKEN cDNA 1500002O20 gene	0.015
Ephx2	epoxide hydrolase 2, cytoplasmic	0.015
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.015
Hp	haptoglobin	0.015
Dgat2	diacylglycerol O-acyltransferase 2	0.014
Rora	RAR-related orphan receptor alpha	0.014
Egr1	early growth response 1	0.014
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.014
Trf	transferrin	0.014
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.014
Cnot3	CCR4-NOT transcription complex, subunit 3	0.014
Rpgrip1l	Rpgrip1-like	0.014
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.014
Prkce	protein kinase C, epsilon	0.014
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.014
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.014
Bcl2	B-cell leukemia/lymphoma 2	0.014
Ptprf	protein tyrosine phosphatase, receptor type, F	0.013
Orm1	orosomucoid 1	0.013
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.013
Ctsl	cathepsin L	0.013
Ces1d	carboxylesterase 1D	0.013
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.013
Fmo1	flavin containing monooxygenase 1	0.013
Pygl	liver glycogen phosphorylase	0.013
Vdr	vitamin D receptor	0.013
Ctnnb1	catenin (cadherin associated protein), beta 1	0.013
Jag2	jagged 2	0.013
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.013
Gli2	GLI-Kruppel family member GLI2	0.013
Cox8b	cytochrome c oxidase, subunit VIIIb	0.013
Lpl	lipoprotein lipase	0.013
Lpcat3	lysophosphatidylcholine acyltransferase 3	0.013
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.013
Fst	follistatin	0.013
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.013
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.012
Ckb	creatine kinase, brain	0.012
C4b	complement component 4B (Childo blood group)	0.012
Myb	myeloblastosis oncogene	0.012
Spen	SPEN homolog, transcriptional regulator (Drosophila)	0.012
Mvd	mevalonate (diphospho) decarboxylase	0.012
Fgf13	fibroblast growth factor 13	0.012
Zfpm1	zinc finger protein, multitype 1	0.012
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.012
Wbp7	WW domain binding protein 7	0.012
Fgfr1	fibroblast growth factor receptor 1	0.012
Ppara	peroxisome proliferator activated receptor alpha	0.012
Tgif2	TGFB-induced factor homeobox 2	0.011
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.011
Sf1	splicing factor 1	0.011
Pim3	proviral integration site 3	0.011
Dab2ip	disabled homolog 2 (Drosophila) interacting protein	0.011
Acsl1	acyl-CoA synthetase long-chain family member 1	0.011
Gnrh1	gonadotropin releasing hormone 1	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Wiz	widely-interspaced zinc finger motifs	0.011
Rxrg	retinoid X receptor gamma	0.011
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.011
Fah	fumarylacetoacetate hydrolase	0.011
Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	0.011
Tgfb1	transforming growth factor, beta 1	0.011
Scd2	stearoyl-Coenzyme A desaturase 2	0.011
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.011
Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	0.011
Stim1	stromal interaction molecule 1	0.011
Fam100a	family with sequence similarity 100, member A	0.011
Inmt	indolethylamine N-methyltransferase	0.011
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.011
Vav2	vav 2 oncogene	0.011
Mapk8	mitogen-activated protein kinase 8	0.011
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.011
Scaf1	SR-related CTD-associated factor 1	0.010
Ret	ret proto-oncogene	0.010
Smagp	small cell adhesion glycoprotein	0.010
Sbf1	SET binding factor 1	0.010
Mgll	monoglyceride lipase	0.010
Ppp6r1	protein phosphatase 6, regulatory subunit 1	0.010
Mtap1b	microtubule-associated protein 1B	0.010
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.010
Auts2	autism susceptibility candidate 2	0.010
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.010
Epha4	Eph receptor A4	0.010
Csf1	colony stimulating factor 1 (macrophage)	0.010
Ube2o	ubiquitin-conjugating enzyme E2O	0.010
Zbtb22	zinc finger and BTB domain containing 22	0.010
Zbtb16	zinc finger and BTB domain containing 16	0.010
Lrp4	low density lipoprotein receptor-related protein 4	0.010