IMP

Process View

Mus musculus

18 genes annotated in mouse

cyclic nucleotide mediated signaling

GO:0019935

Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cyclic nucleotide mediated signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cyclic nucleotide mediated signaling" (in gray)

Name	Description	Probability	Func Analog Organism
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.953
Lepr	leptin receptor	0.854
Esr1	estrogen receptor 1 (alpha)	0.672
Kl	klotho	0.581
Cckbr	cholecystokinin B receptor	0.488
Drd2	dopamine receptor D2	0.430
Adrb1	adrenergic receptor, beta 1	0.400	Human Mouse
Pnpla2	patatin-like phospholipase domain containing 2	0.363
Pparg	peroxisome proliferator activated receptor gamma	0.351
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.347
Rims2	regulating synaptic membrane exocytosis 2	0.270
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.256	Human
Cav1	caveolin 1, caveolae protein	0.251
Ret	ret proto-oncogene	0.223
Smad4	MAD homolog 4 (Drosophila)	0.204
Lep	leptin	0.201
Shc3	src homology 2 domain-containing transforming protein C3	0.184
Nos1	nitric oxide synthase 1, neuronal	0.168
Ghr	growth hormone receptor	0.157
Esr2	estrogen receptor 2 (beta)	0.116
Pten	phosphatase and tensin homolog	0.109
Ccl2	chemokine (C-C motif) ligand 2	0.100
Crhr1	corticotropin releasing hormone receptor 1	0.095	Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.088
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.079
Nos3	nitric oxide synthase 3, endothelial cell	0.078
Fgf10	fibroblast growth factor 10	0.076
Thrb	thyroid hormone receptor beta	0.075
Rims1	regulating synaptic membrane exocytosis 1	0.073	Mouse
Pax8	paired box gene 8	0.070
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.066
Npy2r	neuropeptide Y receptor Y2	0.062
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.051
Kitl	kit ligand	0.050
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.048
Mrvi1	MRV integration site 1	0.048
Prkg1	protein kinase, cGMP-dependent, type I	0.047
Rorb	RAR-related orphan receptor beta	0.047
Galr1	galanin receptor 1	0.043
Sncb	synuclein, beta	0.043
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.042
Oprm1	opioid receptor, mu 1	0.041	Human
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.040
Fbxl20	F-box and leucine-rich repeat protein 20	0.040
Lmx1b	LIM homeobox transcription factor 1 beta	0.039
Ptgs2	prostaglandin-endoperoxide synthase 2	0.039
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.039
Rgs9	regulator of G-protein signaling 9	0.038
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.038
Apc	adenomatosis polyposis coli	0.038
Plcg1	phospholipase C, gamma 1	0.037
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.036
Smad1	MAD homolog 1 (Drosophila)	0.036
Npy1r	neuropeptide Y receptor Y1	0.034
Kcnd1	potassium voltage-gated channel, Shal-related family, member 1	0.033
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.032
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.031
Syt7	synaptotagmin VII	0.031
Fabp4	fatty acid binding protein 4, adipocyte	0.031
Adipoq	adiponectin, C1Q and collagen domain containing	0.030
Mitf	microphthalmia-associated transcription factor	0.030
Rgs4	regulator of G-protein signaling 4	0.029	Mouse
Plcb1	phospholipase C, beta 1	0.029
Acan	aggrecan	0.029
Has2	hyaluronan synthase 2	0.029
Ccbp2	chemokine binding protein 2	0.029
Pdx1	pancreatic and duodenal homeobox 1	0.028
Sntb1	syntrophin, basic 1	0.028
Slc12a1	solute carrier family 12, member 1	0.028
Drd4	dopamine receptor D4	0.027
Drd3	dopamine receptor D3	0.027
Selp	selectin, platelet	0.026
Neurog3	neurogenin 3	0.026
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.026	Mouse
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.026
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.026
Tac2	tachykinin 2	0.026
Ar	androgen receptor	0.025
Il10ra	interleukin 10 receptor, alpha	0.025
Sstr2	somatostatin receptor 2	0.025
Nppb	natriuretic peptide type B	0.025
Htra3	HtrA serine peptidase 3	0.025
Mc5r	melanocortin 5 receptor	0.025
Sstr4	somatostatin receptor 4	0.024
Edil3	EGF-like repeats and discoidin I-like domains 3	0.024
Bcar1	breast cancer anti-estrogen resistance 1	0.024
Ptgfr	prostaglandin F receptor	0.024	Mouse
Nrgn	neurogranin	0.024
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.024
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.024
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.023
Ncam2	neural cell adhesion molecule 2	0.023
Edn2	endothelin 2	0.023
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.023
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.023
Vdr	vitamin D receptor	0.023
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.023
Fut1	fucosyltransferase 1	0.023
Epha6	Eph receptor A6	0.022
Sertad2	SERTA domain containing 2	0.022
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.022
Prkcc	protein kinase C, gamma	0.022
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.022
Kifc2	kinesin family member C2	0.022
Itgb2l	integrin beta 2-like	0.022
Esrrb	estrogen related receptor, beta	0.022
Foxf2	forkhead box F2	0.022
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.022
Ednrb	endothelin receptor type B	0.021	Rat
Cntn3	contactin 3	0.021
Npy5r	neuropeptide Y receptor Y5	0.021
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.021
Igf1	insulin-like growth factor 1	0.021
Gng4	guanine nucleotide binding protein (G protein), gamma 4	0.021
Gpr83	G protein-coupled receptor 83	0.021
Gpr33	G protein-coupled receptor 33	0.021
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.020
Kcne2	potassium voltage-gated channel, Isk-related subfamily, gene 2	0.020
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.020
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.020
S100a5	S100 calcium binding protein A5	0.020
Cga	glycoprotein hormones, alpha subunit	0.020
Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	0.020
Npr1	natriuretic peptide receptor 1	0.020
Aff2	AF4/FMR2 family, member 2	0.020
Cacng5	calcium channel, voltage-dependent, gamma subunit 5	0.020
Insr	insulin receptor	0.020
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.020
Adm	adrenomedullin	0.019
Col4a3	collagen, type IV, alpha 3	0.019
Adora2a	adenosine A2a receptor	0.019
Smad3	MAD homolog 3 (Drosophila)	0.019
Nf1	neurofibromatosis 1	0.019	Fly
Kcnk3	potassium channel, subfamily K, member 3	0.019
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.019
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.019
Fgf1	fibroblast growth factor 1	0.019
Il9r	interleukin 9 receptor	0.019
Npy6r	neuropeptide Y receptor Y6	0.019
Darc	Duffy blood group, chemokine receptor	0.019
Ptprb	protein tyrosine phosphatase, receptor type, B	0.018
Cxcl2	chemokine (C-X-C motif) ligand 2	0.018
Sspo	SCO-spondin	0.018
ND6	NADH dehydrogenase subunit 6	0.018
Tbx6	T-box 6	0.018
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.018	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.018
Fgfr3	fibroblast growth factor receptor 3	0.018
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.018
Angpt1	angiopoietin 1	0.017
Bcl2	B-cell leukemia/lymphoma 2	0.017
Tpsb2	tryptase beta 2	0.017
S1pr1	sphingosine-1-phosphate receptor 1	0.017
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.017
Tll1	tolloid-like	0.017
Cd247	CD247 antigen	0.017
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.017
Bmx	BMX non-receptor tyrosine kinase	0.017
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.017
Pomc	pro-opiomelanocortin-alpha	0.017
Ptch1	patched homolog 1	0.017
Fyn	Fyn proto-oncogene	0.016
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.016
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.016
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.016
Hrh3	histamine receptor H3	0.016
Sst	somatostatin	0.016
Tacr1	tachykinin receptor 1	0.016
Clcnka	chloride channel Ka	0.016
Gcgr	glucagon receptor	0.016	Mouse
Nrsn1	neurensin 1	0.016
Npas2	neuronal PAS domain protein 2	0.016
Vav2	vav 2 oncogene	0.016
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.016
Cnr1	cannabinoid receptor 1 (brain)	0.016
Sstr3	somatostatin receptor 3	0.016
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.016
Ldlr	low density lipoprotein receptor	0.016
Itgb3	integrin beta 3	0.016
Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	0.016
Eif4a2	eukaryotic translation initiation factor 4A2	0.016
Gnrhr	gonadotropin releasing hormone receptor	0.015
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.015
Acr	acrosin prepropeptide	0.015
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.015
Trfr2	transferrin receptor 2	0.015
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.015
Prnp	prion protein	0.015
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.015
Gsx1	GS homeobox 1	0.015
Rictor	RPTOR independent companion of MTOR, complex 2	0.015
Avpr2	arginine vasopressin receptor 2	0.015
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.015
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.015
Ltc4s	leukotriene C4 synthase	0.015
Hrh1	histamine receptor H1	0.015
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.015
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.015
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.015
Gpr27	G protein-coupled receptor 27	0.015
Alk	anaplastic lymphoma kinase	0.015
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.015
Kit	kit oncogene	0.015
Lrp6	low density lipoprotein receptor-related protein 6	0.015
Fshb	follicle stimulating hormone beta	0.015
Cbx7	chromobox homolog 7	0.015
Oxtr	oxytocin receptor	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.014
Grm2	glutamate receptor, metabotropic 2	0.014
Pgr	progesterone receptor	0.014
Csf3	colony stimulating factor 3 (granulocyte)	0.014
Alox8	arachidonate 8-lipoxygenase	0.014
Csmd1	CUB and Sushi multiple domains 1	0.014
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.014
Cntn2	contactin 2	0.014
Lhx3	LIM homeobox protein 3	0.014
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.014
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.014
Wnt2b	wingless related MMTV integration site 2b	0.014
Prkcb	protein kinase C, beta	0.014
Oprk1	opioid receptor, kappa 1	0.014
Prl8a2	prolactin family 8, subfamily a, member 2	0.014
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.014
Edn1	endothelin 1	0.014
Gcet2	germinal center expressed transcript 2	0.014
Gab2	growth factor receptor bound protein 2-associated protein 2	0.014
Ptafr	platelet-activating factor receptor	0.014
Rab3a	RAB3A, member RAS oncogene family	0.014
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.014	Mouse
Tgfbr3	transforming growth factor, beta receptor III	0.014
L1cam	L1 cell adhesion molecule	0.014
Sox10	SRY-box containing gene 10	0.014
Syn2	synapsin II	0.013
Src	Rous sarcoma oncogene	0.013
Cryaa	crystallin, alpha A	0.013
Apoe	apolipoprotein E	0.013	Human
Ptprr	protein tyrosine phosphatase, receptor type, R	0.013
Irs2	insulin receptor substrate 2	0.013
Rasgrp1	RAS guanyl releasing protein 1	0.013
Lpl	lipoprotein lipase	0.013
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.013
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.013
Fgf7	fibroblast growth factor 7	0.013
Ptgir	prostaglandin I receptor (IP)	0.013
Rgs14	regulator of G-protein signaling 14	0.013
Dnm1	dynamin 1	0.013
Wnt1	wingless-related MMTV integration site 1	0.013
Rgs17	regulator of G-protein signaling 17	0.013
Foxa2	forkhead box A2	0.013
Egr1	early growth response 1	0.013
Igf1r	insulin-like growth factor I receptor	0.013
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.013
Pax6	paired box gene 6	0.013
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.013
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.013
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.013
Chrnb3	cholinergic receptor, nicotinic, beta polypeptide 3	0.013
Itga2	integrin alpha 2	0.013
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.013
Nhedc2	Na+/H+ exchanger domain containing 2	0.013
Wnt3	wingless-related MMTV integration site 3	0.013
Mmp24	matrix metallopeptidase 24	0.013
Abhd5	abhydrolase domain containing 5	0.013
Nxph2	neurexophilin 2	0.013
Olfr71	olfactory receptor 71	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Fgf4	fibroblast growth factor 4	0.013
Cx3cr1	chemokine (C-X3-C) receptor 1	0.013
Prss30	protease, serine, 30	0.013
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.013
Agtr1a	angiotensin II receptor, type 1a	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Lhx6	LIM homeobox protein 6	0.012
Chl1	cell adhesion molecule with homology to L1CAM	0.012
Rasgrp2	RAS, guanyl releasing protein 2	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Insm1	insulinoma-associated 1	0.012
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.012
Ntsr2	neurotensin receptor 2	0.012
Dio2	deiodinase, iodothyronine, type II	0.012
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.012
Dlx4	distal-less homeobox 4	0.012
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.012
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.012
Klhl24	kelch-like 24 (Drosophila)	0.012
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.012
Fndc7	fibronectin type III domain containing 7	0.012
Ptpro	protein tyrosine phosphatase, receptor type, O	0.012
Clk4	CDC like kinase 4	0.012
Nrg3	neuregulin 3	0.012
Pthlh	parathyroid hormone-like peptide	0.012
U46068	cDNA sequence U46068	0.012
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.012
Plau	plasminogen activator, urokinase	0.012
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.012
Cntn4	contactin 4	0.012
Rhoj	ras homolog gene family, member J	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Sim1	single-minded homolog 1 (Drosophila)	0.012
Cplx3	complexin 3	0.011
Braf	Braf transforming gene	0.011
Bdkrb2	bradykinin receptor, beta 2	0.011
Aanat	arylalkylamine N-acetyltransferase	0.011
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.011	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.011
Vsx2	visual system homeobox 2	0.011
Neurod1	neurogenic differentiation 1	0.011
Pln	phospholamban	0.011
Pkd1	polycystic kidney disease 1 homolog	0.011
Scd1	stearoyl-Coenzyme A desaturase 1	0.011
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.011
Tspo2	translocator protein 2	0.011
Krt86	keratin 86	0.011
Pdgfb	platelet derived growth factor, B polypeptide	0.011
Cdh6	cadherin 6	0.011
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.011
Syt17	synaptotagmin XVII	0.011
Hnf1b	HNF1 homeobox B	0.011
Ppyr1	pancreatic polypeptide receptor 1	0.011
Vil1	villin 1	0.011
Myl10	myosin, light chain 10, regulatory	0.011
Syt6	synaptotagmin VI	0.011
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.011
Gpr12	G-protein coupled receptor 12	0.011
Gad2	glutamic acid decarboxylase 2	0.011
Kiss1r	KISS1 receptor	0.011
Foxb2	forkhead box B2	0.011
Ryr3	ryanodine receptor 3	0.011
Slc4a8	solute carrier family 4 (anion exchanger), member 8	0.011
Mchr1	melanin-concentrating hormone receptor 1	0.011
Il3	interleukin 3	0.011
Amhr2	anti-Mullerian hormone type 2 receptor	0.011
Grid2	glutamate receptor, ionotropic, delta 2	0.011
Zfand5	zinc finger, AN1-type domain 5	0.011
Khdc1b	KH domain containing 1B	0.011
Prox1	prospero-related homeobox 1	0.011
Mc3r	melanocortin 3 receptor	0.011
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.011
Rxra	retinoid X receptor alpha	0.011
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.010
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.010
Mpl	myeloproliferative leukemia virus oncogene	0.010
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.010
Tgfa	transforming growth factor alpha	0.010
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.010
Flt1	FMS-like tyrosine kinase 1	0.010
Btbd17	BTB (POZ) domain containing 17	0.010
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.010
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.010
St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.010
Masp1	mannan-binding lectin serine peptidase 1	0.010
Gast	gastrin	0.010
Pear1	platelet endothelial aggregation receptor 1	0.010
Fam164c	family with sequence similarity 164, member C	0.010
Grid1	glutamate receptor, ionotropic, delta 1	0.010
Wnt7a	wingless-related MMTV integration site 7A	0.010
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.010
Foxk1	forkhead box K1	0.010
Plat	plasminogen activator, tissue	0.010
Bmp4	bone morphogenetic protein 4	0.010
Pcdh12	protocadherin 12	0.010
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.010