IMP

Process View

Mus musculus

14 genes annotated in mouse

cellular response to oxygen radical

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to oxygen radical"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to oxygen radical" (in gray)

Name	Description	Probability	Func Analog Organism
Fbn1	fibrillin 1	0.985
Tgfbr2	transforming growth factor, beta receptor II	0.977
Lox	lysyl oxidase	0.959
Apoe	apolipoprotein E	0.923
Eln	elastin	0.702
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.564
Ldlr	low density lipoprotein receptor	0.550
Mmp2	matrix metallopeptidase 2	0.437
Tgfbr1	transforming growth factor, beta receptor I	0.386
Smo	smoothened homolog (Drosophila)	0.369
Klf1	Kruppel-like factor 1 (erythroid)	0.277
Agtr1a	angiotensin II receptor, type 1a	0.237
Slc31a1	solute carrier family 31, member 1	0.198
Steap3	STEAP family member 3	0.153
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.117	Mouse
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.099
Hbb-b1	hemoglobin, beta adult major chain	0.092
Mcl1	myeloid cell leukemia sequence 1	0.091
Gcsh	glycine cleavage system protein H (aminomethyl carrier)	0.089
Tgfb2	transforming growth factor, beta 2	0.087
Foxc1	forkhead box C1	0.087
Mt2	metallothionein 2	0.083
Idua	iduronidase, alpha-L-	0.080
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.076
Lamp2	lysosomal-associated membrane protein 2	0.072
E2f1	E2F transcription factor 1	0.070
Slc12a6	solute carrier family 12, member 6	0.068
Tenc1	tensin like C1 domain-containing phosphatase	0.067
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.067
Ifngr1	interferon gamma receptor 1	0.065
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.062
Dbi	diazepam binding inhibitor	0.062
Lrp1	low density lipoprotein receptor-related protein 1	0.062
Sod3	superoxide dismutase 3, extracellular	0.060
Romo1	reactive oxygen species modulator 1	0.056
Vegfa	vascular endothelial growth factor A	0.055
Tal1	T-cell acute lymphocytic leukemia 1	0.053
Prnp	prion protein	0.053
Duox2	dual oxidase 2	0.052
Cav1	caveolin 1, caveolae protein	0.052
Tlr4	toll-like receptor 4	0.048
Agtr2	angiotensin II receptor, type 2	0.048
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.044
Fgfr1	fibroblast growth factor receptor 1	0.040
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.039
Figf	c-fos induced growth factor	0.039
Camp	cathelicidin antimicrobial peptide	0.039
Rhd	Rh blood group, D antigen	0.036
Col6a1	collagen, type VI, alpha 1	0.035
Mrc2	mannose receptor, C type 2	0.034
Loxl1	lysyl oxidase-like 1	0.033
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.033
Col16a1	collagen, type XVI, alpha 1	0.032
Prelp	proline arginine-rich end leucine-rich repeat	0.032
Hint1	histidine triad nucleotide binding protein 1	0.032
Thbs2	thrombospondin 2	0.032
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.032
Spna1	spectrin alpha 1	0.031
Kat2a	K(lysine) acetyltransferase 2A	0.030
Smad1	MAD homolog 1 (Drosophila)	0.030
Thbs3	thrombospondin 3	0.030
Ngp	neutrophilic granule protein	0.030
Gp1ba	glycoprotein 1b, alpha polypeptide	0.030
Ptrf	polymerase I and transcript release factor	0.028
Timp3	tissue inhibitor of metalloproteinase 3	0.028
Qdpr	quinoid dihydropteridine reductase	0.027
Tgfb1	transforming growth factor, beta 1	0.027
Epor	erythropoietin receptor	0.027
Thrb	thyroid hormone receptor beta	0.027
Hyal3	hyaluronoglucosaminidase 3	0.026
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.026
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.026
Fam96a	family with sequence similarity 96, member A	0.025
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.025
Fzd2	frizzled homolog 2 (Drosophila)	0.025
Creg1	cellular repressor of E1A-stimulated genes 1	0.024
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.024
Cycs	cytochrome c, somatic	0.024
Mus81	MUS81 endonuclease homolog (yeast)	0.023
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.023
Col1a2	collagen, type I, alpha 2	0.023
Car1	carbonic anhydrase 1	0.023
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.023
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.023
Lamb2	laminin, beta 2	0.022
Sorbs3	sorbin and SH3 domain containing 3	0.022
Leprel2	leprecan-like 2	0.022
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.022
Scara3	scavenger receptor class A, member 3	0.022
Ednra	endothelin receptor type A	0.022
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.021
Jag1	jagged 1	0.021
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.021
Cp	ceruloplasmin	0.021
Bcap31	B-cell receptor-associated protein 31	0.020
Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.020
Lage3	L antigen family, member 3	0.020
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.020
Nos3	nitric oxide synthase 3, endothelial cell	0.020
Cfh	complement component factor h	0.020
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.019
Ep300	E1A binding protein p300	0.019
Adh5	alcohol dehydrogenase 5 (class III), chi polypeptide	0.019
Lass2	LAG1 homolog, ceramide synthase 2	0.019
Pkd1	polycystic kidney disease 1 homolog	0.019
Aebp1	AE binding protein 1	0.019
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.018
Fam136a	family with sequence similarity 136, member A	0.018
Mrpl16	mitochondrial ribosomal protein L16	0.018
Elane	elastase, neutrophil expressed	0.018
Slc12a4	solute carrier family 12, member 4	0.018
Kit	kit oncogene	0.018
Cyb5	cytochrome b-5	0.017
Tmco1	transmembrane and coiled-coil domains 1	0.017
Btg1	B-cell translocation gene 1, anti-proliferative	0.017
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.017
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.017
Sp1	trans-acting transcription factor 1	0.017
Gja1	gap junction protein, alpha 1	0.016
Gypa	glycophorin A	0.016
Tnxb	tenascin XB	0.016
Tle2	transducin-like enhancer of split 2, homolog of Drosophila E(spl)	0.016
Mmp11	matrix metallopeptidase 11	0.016
Casp3	caspase 3	0.016
Mrps17	mitochondrial ribosomal protein S17	0.016
Htra1	HtrA serine peptidase 1	0.015
Slit3	slit homolog 3 (Drosophila)	0.015
Trp53	transformation related protein 53	0.015
Gata1	GATA binding protein 1	0.015
Wbp7	WW domain binding protein 7	0.015
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.015
Igfbp6	insulin-like growth factor binding protein 6	0.015
Hoxa1	homeobox A1	0.015
Gp5	glycoprotein 5 (platelet)	0.015
Igfbp3	insulin-like growth factor binding protein 3	0.015
Upk3b	uroplakin 3B	0.015
Kdm6a	4lysine (K)-specific demethylase 6A	0.015
Stat3	signal transducer and activator of transcription 3	0.014
Klf10	Kruppel-like factor 10	0.014
H2afx	H2A histone family, member X	0.014
Dpep1	dipeptidase 1 (renal)	0.014
Epb4.2	erythrocyte protein band 4.2	0.014
Gaa	glucosidase, alpha, acid	0.014
Ctsg	cathepsin G	0.014
Mt1	metallothionein 1	0.014
Aurkb	aurora kinase B	0.014
Col4a5	collagen, type IV, alpha 5	0.014
Paics	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase	0.014
Gp9	glycoprotein 9 (platelet)	0.014
Gata3	GATA binding protein 3	0.013
Eci2	enoyl-Coenzyme A delta isomerase 2	0.013
Mpo	myeloperoxidase	0.013
Slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.013
Dusp1	dual specificity phosphatase 1	0.013
Rhbdf1	rhomboid family 1 (Drosophila)	0.013
Pcolce	procollagen C-endopeptidase enhancer protein	0.013
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.013
Mcam	melanoma cell adhesion molecule	0.013
Uqcrb	ubiquinol-cytochrome c reductase binding protein	0.013
Mmp8	matrix metallopeptidase 8	0.013
Zfp521	zinc finger protein 521	0.013
Chd2	chromodomain helicase DNA binding protein 2	0.013
Tspo2	translocator protein 2	0.013
Txn1	thioredoxin 1	0.012
Ltf	lactotransferrin	0.012
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.012
X99384	cDNA sequence X99384	0.012
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.012
Tlr2	toll-like receptor 2	0.012
Pklr	pyruvate kinase liver and red blood cell	0.012
Tshr	thyroid stimulating hormone receptor	0.012
Sqstm1	sequestosome 1	0.012
C3	complement component 3	0.012
Rdh10	retinol dehydrogenase 10 (all-trans)	0.012
Gsto1	glutathione S-transferase omega 1	0.012
Pgk1	phosphoglycerate kinase 1	0.012
Ufc1	ubiquitin-fold modifier conjugating enzyme 1	0.012
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.012
Tpp1	tripeptidyl peptidase I	0.012
Klk1b1	kallikrein 1-related peptidase b1	0.012
Pmpcb	peptidase (mitochondrial processing) beta	0.012
Mkl2	MKL/myocardin-like 2	0.012
Lpl	lipoprotein lipase	0.012
Lama4	laminin, alpha 4	0.012
Fh1	fumarate hydratase 1	0.012
Bgn	biglycan	0.012
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.012
Lama2	laminin, alpha 2	0.011
Itga2b	integrin alpha 2b	0.011
Lamc2	laminin, gamma 2	0.011
Hdac7	histone deacetylase 7	0.011
Hic1	hypermethylated in cancer 1	0.011
Glrx3	glutaredoxin 3	0.011
Tgfb3	transforming growth factor, beta 3	0.011
Fmod	fibromodulin	0.011
Cul7	cullin 7	0.011
Pitrm1	pitrilysin metallepetidase 1	0.011
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.011
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.011
Cngb1	cyclic nucleotide gated channel beta 1	0.011
Sulf1	sulfatase 1	0.011
Uqcrc2	ubiquinol cytochrome c reductase core protein 2	0.011
Hmgn1	high mobility group nucleosomal binding domain 1	0.011
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.011
Col6a2	collagen, type VI, alpha 2	0.011
Ndufb6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6	0.011
Mrpl35	mitochondrial ribosomal protein L35	0.011
Alad	aminolevulinate, delta-, dehydratase	0.011
Smoc2	SPARC related modular calcium binding 2	0.011
Txndc17	thioredoxin domain containing 17	0.010
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.010
Urod	uroporphyrinogen decarboxylase	0.010
Prickle2	prickle homolog 2 (Drosophila)	0.010
Mfap4	microfibrillar-associated protein 4	0.010
Emp2	epithelial membrane protein 2	0.010
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.010
Pdgfb	platelet derived growth factor, B polypeptide	0.010
Kel	Kell blood group	0.010
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.010
Tars2	threonyl-tRNA synthetase 2, mitochondrial (putative)	0.010
Hspa9	heat shock protein 9	0.010
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.010
Heph	hephaestin	0.010