IMP

Process View

Mus musculus

12 genes annotated in mouse

cell differentiation involved in metanephros development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell differentiation involved in metanephros development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell differentiation involved in metanephros development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	1.000
C1qb	complement component 1, q subcomponent, beta polypeptide	0.921	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.910
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.891
Lamc1	laminin, gamma 1	0.876	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.860
Otx2	orthodenticle homolog 2 (Drosophila)	0.827
Sox2	SRY-box containing gene 2	0.795
Tbx1	T-box 1	0.735
Wwtr1	WW domain containing transcription regulator 1	0.705
Gli3	GLI-Kruppel family member GLI3	0.676
Shh	sonic hedgehog	0.671
Rarg	retinoic acid receptor, gamma	0.613
Foxg1	forkhead box G1	0.611
Esr1	estrogen receptor 1 (alpha)	0.608
Ar	androgen receptor	0.597
Wt1	Wilms tumor 1 homolog	0.569
Lhx1	LIM homeobox protein 1	0.486
Fgf10	fibroblast growth factor 10	0.472
Eya1	eyes absent 1 homolog (Drosophila)	0.447
Bmp4	bone morphogenetic protein 4	0.430
Bcl2	B-cell leukemia/lymphoma 2	0.416
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.390
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.375
Pax3	paired box gene 3	0.364
Tbx10	T-box 10	0.332
Hoxa1	homeobox A1	0.316
Otx1	orthodenticle homolog 1 (Drosophila)	0.305
Pax8	paired box gene 8	0.304
Hmx3	H6 homeobox 3	0.293
Chd7	chromodomain helicase DNA binding protein 7	0.287
Lama5	laminin, alpha 5	0.287
C1qc	complement component 1, q subcomponent, C chain	0.287	Mouse
Foxc2	forkhead box C2	0.254
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.229	Mouse
Lef1	lymphoid enhancer binding factor 1	0.227
Duox2	dual oxidase 2	0.216
Msx1	homeobox, msh-like 1	0.214
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.213
Fgf8	fibroblast growth factor 8	0.201
Pax6	paired box gene 6	0.200
Yap1	yes-associated protein 1	0.199
Jag1	jagged 1	0.193
Lhx3	LIM homeobox protein 3	0.190
Nos3	nitric oxide synthase 3, endothelial cell	0.187
Wnt6	wingless-related MMTV integration site 6	0.181
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.177
Pitx2	paired-like homeodomain transcription factor 2	0.173
Foxc1	forkhead box C1	0.165
Vegfa	vascular endothelial growth factor A	0.158	Mouse
Nid1	nidogen 1	0.156
Fbln1	fibulin 1	0.149
Trp63	transformation related protein 63	0.127
Isl1	ISL1 transcription factor, LIM/homeodomain	0.120
Dlx5	distal-less homeobox 5	0.116
Tead1	TEA domain family member 1	0.113
Lmx1a	LIM homeobox transcription factor 1 alpha	0.113
Gbx2	gastrulation brain homeobox 2	0.111
Ly86	lymphocyte antigen 86	0.111
Cga	glycoprotein hormones, alpha subunit	0.107
S1pr2	sphingosine-1-phosphate receptor 2	0.103
Tyrobp	TYRO protein tyrosine kinase binding protein	0.102
Tead3	TEA domain family member 3	0.101
Bdnf	brain derived neurotrophic factor	0.097
Insm1	insulinoma-associated 1	0.096
Hes5	hairy and enhancer of split 5 (Drosophila)	0.096
Lhx9	LIM homeobox protein 9	0.094
Flt4	FMS-like tyrosine kinase 4	0.091
Apoe	apolipoprotein E	0.088
Zfp503	zinc finger protein 503	0.081
Rarb	retinoic acid receptor, beta	0.080
Hoxd13	homeobox D13	0.078
Lmx1b	LIM homeobox transcription factor 1 beta	0.075
Aif1	allograft inflammatory factor 1	0.073
Emx1	empty spiracles homolog 1 (Drosophila)	0.070
Hoxa11	homeobox A11	0.069
Efnb2	ephrin B2	0.067
Gdnf	glial cell line derived neurotrophic factor	0.067
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.066
Ghr	growth hormone receptor	0.065
Twist2	twist homolog 2 (Drosophila)	0.059
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.056
Wnt7b	wingless-related MMTV integration site 7B	0.056
Fgfr1	fibroblast growth factor receptor 1	0.056
Lamb1	laminin B1	0.055	Mouse
Foxi1	forkhead box I1	0.055
Drd2	dopamine receptor D2	0.054
Rara	retinoic acid receptor, alpha	0.053
Fgf3	fibroblast growth factor 3	0.053
Gdf11	growth differentiation factor 11	0.052
Hoxb1	homeobox B1	0.052
Hmx1	H6 homeobox 1	0.051
Tg	thyroglobulin	0.050
Smad6	MAD homolog 6 (Drosophila)	0.049
Sall4	sal-like 4 (Drosophila)	0.049
Wnt4	wingless-related MMTV integration site 4	0.049
Tcfap2c	transcription factor AP-2, gamma	0.048
Wnt9b	wingless-type MMTV integration site 9B	0.047
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.046
Wnt1	wingless-related MMTV integration site 1	0.044
Lama2	laminin, alpha 2	0.044
Wwc2	WW, C2 and coiled-coil domain containing 2	0.043
Neurog3	neurogenin 3	0.041
Gata6	GATA binding protein 6	0.041
Nog	noggin	0.040
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.040
Hand2	heart and neural crest derivatives expressed transcript 2	0.039
Kdr	kinase insert domain protein receptor	0.039
Wnt7a	wingless-related MMTV integration site 7A	0.038
Notch2	Notch gene homolog 2 (Drosophila)	0.036
Msx2	homeobox, msh-like 2	0.036
Tgfb2	transforming growth factor, beta 2	0.035
Foxf2	forkhead box F2	0.034
Vangl2	vang-like 2 (van gogh, Drosophila)	0.033
Krt15	keratin 15	0.033
Csf1r	colony stimulating factor 1 receptor	0.033
Atoh7	atonal homolog 7 (Drosophila)	0.032
Bmp7	bone morphogenetic protein 7	0.032
Dchs1	dachsous 1 (Drosophila)	0.032
Vsx2	visual system homeobox 2	0.032
Lhx5	LIM homeobox protein 5	0.031
Gpc3	glypican 3	0.031
Efna4	ephrin A4	0.031
Efna2	ephrin A2	0.030
Hoxa4	homeobox A4	0.030
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.030
Dlx2	distal-less homeobox 2	0.029
Neurod1	neurogenic differentiation 1	0.029
Mrc1	mannose receptor, C type 1	0.029
Adrb1	adrenergic receptor, beta 1	0.028
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.028
Fgf18	fibroblast growth factor 18	0.028
Dlx1	distal-less homeobox 1	0.028
Ptk7	PTK7 protein tyrosine kinase 7	0.028
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.027
Gas1	growth arrest specific 1	0.027
Ctnnb1	catenin (cadherin associated protein), beta 1	0.027
Ddr2	discoidin domain receptor family, member 2	0.027
Lzts2	leucine zipper, putative tumor suppressor 2	0.027
Rxra	retinoid X receptor alpha	0.027
Crhr1	corticotropin releasing hormone receptor 1	0.026
Tcfap2a	transcription factor AP-2, alpha	0.026
Fzd4	frizzled homolog 4 (Drosophila)	0.026
Nanog	Nanog homeobox	0.026
Kl	klotho	0.025
Ntn4	netrin 4	0.025	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.025
Fgf15	fibroblast growth factor 15	0.025
Sox10	SRY-box containing gene 10	0.025
Zeb1	zinc finger E-box binding homeobox 1	0.025
Tead2	TEA domain family member 2	0.024
Kiss1	KiSS-1 metastasis-suppressor	0.024
Kiss1r	KISS1 receptor	0.024
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.024
Npr3	natriuretic peptide receptor 3	0.024
Gli2	GLI-Kruppel family member GLI2	0.024
Hoxd11	homeobox D11	0.024
Sall3	sal-like 3 (Drosophila)	0.024
Msi1	Musashi homolog 1(Drosophila)	0.024
Gab2	growth factor receptor bound protein 2-associated protein 2	0.023
Foxd2	forkhead box D2	0.023
Smo	smoothened homolog (Drosophila)	0.023
Gata3	GATA binding protein 3	0.022
Bnc1	basonuclin 1	0.022
Ighmbp2	immunoglobulin mu binding protein 2	0.022
Hand1	heart and neural crest derivatives expressed transcript 1	0.021
Hoxa3	homeobox A3	0.021
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.021	Mouse
Ebf3	early B-cell factor 3	0.021
Slc26a4	solute carrier family 26, member 4	0.021
Igfbp3	insulin-like growth factor binding protein 3	0.021
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.020
Krt14	keratin 14	0.020
Foxf1a	forkhead box F1a	0.020
Efna3	ephrin A3	0.020
Gsc	goosecoid homeobox	0.020
Atoh1	atonal homolog 1 (Drosophila)	0.020
Uncx	UNC homeobox	0.020
Pdgfc	platelet-derived growth factor, C polypeptide	0.020
Tlx2	T-cell leukemia, homeobox 2	0.020
Nrxn1	neurexin I	0.020
Il11	interleukin 11	0.020
Bcan	brevican	0.019
Hoxd9	homeobox D9	0.019
Lhx4	LIM homeobox protein 4	0.019
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.019
Ltbp1	latent transforming growth factor beta binding protein 1	0.019
Twist1	twist homolog 1 (Drosophila)	0.019
T	brachyury	0.019
Foxh1	forkhead box H1	0.019
Lama4	laminin, alpha 4	0.019
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.018
Bmp6	bone morphogenetic protein 6	0.018
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.018
Gucy2e	guanylate cyclase 2e	0.018
Wnt3a	wingless-related MMTV integration site 3A	0.018
Pkp1	plakophilin 1	0.018
Notch3	Notch gene homolog 3 (Drosophila)	0.018
Nkx2-1	NK2 homeobox 1	0.017
Nid2	nidogen 2	0.017
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.017
Bdkrb2	bradykinin receptor, beta 2	0.017
Irx1	Iroquois related homeobox 1 (Drosophila)	0.017
Epha4	Eph receptor A4	0.017
Zic3	zinc finger protein of the cerebellum 3	0.017
Fbn2	fibrillin 2	0.017
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.017
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.016
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.016
Robo3	roundabout homolog 3 (Drosophila)	0.016
Fcgr3	Fc receptor, IgG, low affinity III	0.016
Irx2	Iroquois related homeobox 2 (Drosophila)	0.016
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.016
Tbx2	T-box 2	0.016
Pou4f2	POU domain, class 4, transcription factor 2	0.016	Mouse
Syt7	synaptotagmin VII	0.016
Lama1	laminin, alpha 1	0.016
Alx4	aristaless-like homeobox 4	0.016
Ret	ret proto-oncogene	0.015
Pbx1	pre B-cell leukemia transcription factor 1	0.015
Tcf21	transcription factor 21	0.015
Inhbb	inhibin beta-B	0.015
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.015
Fgf4	fibroblast growth factor 4	0.015
Mdfi	MyoD family inhibitor	0.015
Mpeg1	macrophage expressed gene 1	0.015
Inha	inhibin alpha	0.015
Gli1	GLI-Kruppel family member GLI1	0.015
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.015
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.015
Hoxd3	homeobox D3	0.015
Neurog2	neurogenin 2	0.015
Rpe65	retinal pigment epithelium 65	0.015
Lama3	laminin, alpha 3	0.015
Cidec	cell death-inducing DFFA-like effector c	0.015
Ltbp4	latent transforming growth factor beta binding protein 4	0.014
Cdx1	caudal type homeobox 1	0.014
Tbx3	T-box 3	0.014
Trp73	transformation related protein 73	0.014
Prph	peripherin	0.014
Sox1	SRY-box containing gene 1	0.014
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.014
Cfp	complement factor properdin	0.014
Pld4	phospholipase D family, member 4	0.014
Sox3	SRY-box containing gene 3	0.014
Hbegf	heparin-binding EGF-like growth factor	0.014
Sox21	SRY-box containing gene 21	0.014
Pgr	progesterone receptor	0.014
Amhr2	anti-Mullerian hormone type 2 receptor	0.014
Zfp42	zinc finger protein 42	0.014
Aes	amino-terminal enhancer of split	0.014
Bglap	bone gamma carboxyglutamate protein	0.014
Fkbp9	FK506 binding protein 9	0.014
Cd68	CD68 antigen	0.014
Ednra	endothelin receptor type A	0.014
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.014
Acvr1	activin A receptor, type 1	0.014
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.013
Aoc3	amine oxidase, copper containing 3	0.013
Fbln2	fibulin 2	0.013
Prlr	prolactin receptor	0.013
Prop1	paired like homeodomain factor 1	0.013
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Ntf3	neurotrophin 3	0.013
Irs2	insulin receptor substrate 2	0.013
Ece1	endothelin converting enzyme 1	0.013
Sox9	SRY-box containing gene 9	0.013
Nfib	nuclear factor I/B	0.013
Foxe1	forkhead box E1	0.013
Fst	follistatin	0.013
Cmklr1	chemokine-like receptor 1	0.013
Gjc1	gap junction protein, gamma 1	0.012
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.012
Tnni2	troponin I, skeletal, fast 2	0.012
Nkd1	naked cuticle 1 homolog (Drosophila)	0.012
Grid1	glutamate receptor, ionotropic, delta 1	0.012
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.012
Nrtn	neurturin	0.012
Sox11	SRY-box containing gene 11	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.012
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
Egfr	epidermal growth factor receptor	0.012
Myl10	myosin, light chain 10, regulatory	0.012
Thbd	thrombomodulin	0.012
Vgf	VGF nerve growth factor inducible	0.011
Sox8	SRY-box containing gene 8	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Ybx2	Y box protein 2	0.011
Phldb2	pleckstrin homology-like domain, family B, member 2	0.011
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.011
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.011
Hoxc9	homeobox C9	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.011
Lyz2	lysozyme 2	0.011
Cdh13	cadherin 13	0.011
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Gaa	glucosidase, alpha, acid	0.011
Stra8	stimulated by retinoic acid gene 8	0.011
Lyz1	lysozyme 1	0.011
Plcd1	phospholipase C, delta 1	0.011
Igf1	insulin-like growth factor 1	0.011
Itga3	integrin alpha 3	0.011
Prrx1	paired related homeobox 1	0.011
Grik3	glutamate receptor, ionotropic, kainate 3	0.011
Thrb	thyroid hormone receptor beta	0.011
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Cdsn	corneodesmosin	0.010
Frmd6	FERM domain containing 6	0.010
Col4a5	collagen, type IV, alpha 5	0.010
Neurog1	neurogenin 1	0.010
Nos2	nitric oxide synthase 2, inducible	0.010
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.010
Hoxa13	homeobox A13	0.010
Phox2a	paired-like homeobox 2a	0.010
Emp2	epithelial membrane protein 2	0.010
Polr1a	polymerase (RNA) I polypeptide A	0.010
Igl	immunoglobulin lambda chain complex	0.010
Syt6	synaptotagmin VI	0.010
Myo10	myosin X	0.010
Prdm5	PR domain containing 5	0.010
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.010
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.010