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Mus musculus

8 genes annotated in mouse

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hypothalamus cell differentiation

GO:0021979

The differentiation of cells that will contribute to the structure and function of the hypothalamus.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hypothalamus cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hypothalamus cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Sox2	SRY-box containing gene 2	0.991
Gli3	GLI-Kruppel family member GLI3	0.942
Eya1	eyes absent 1 homolog (Drosophila)	0.929
Pax2	paired box gene 2	0.923
Fgf8	fibroblast growth factor 8	0.923
Sim1	single-minded homolog 1 (Drosophila)	0.883	Zebrafish
Pax6	paired box gene 6	0.879
Msx1	homeobox, msh-like 1	0.876
Pax3	paired box gene 3	0.853
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.845
Lhx3	LIM homeobox protein 3	0.814
Insm1	insulinoma-associated 1	0.800
Pou3f2	POU domain, class 3, transcription factor 2	0.756
Atoh7	atonal homolog 7 (Drosophila)	0.752
Sall3	sal-like 3 (Drosophila)	0.715
Shh	sonic hedgehog	0.710
Pitx2	paired-like homeodomain transcription factor 2	0.693
Chd7	chromodomain helicase DNA binding protein 7	0.692
Hand1	heart and neural crest derivatives expressed transcript 1	0.689
Foxg1	forkhead box G1	0.658
Isl1	ISL1 transcription factor, LIM/homeodomain	0.574
Emx1	empty spiracles homolog 1 (Drosophila)	0.569
Plxnd1	plexin D1	0.481
Hmx3	H6 homeobox 3	0.463
Hand2	heart and neural crest derivatives expressed transcript 2	0.433
Tcfap2a	transcription factor AP-2, alpha	0.431
Fgfr2	fibroblast growth factor receptor 2	0.416
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.370
Sall4	sal-like 4 (Drosophila)	0.369
Zic2	zinc finger protein of the cerebellum 2	0.366
Msx2	homeobox, msh-like 2	0.359
Msi1	Musashi homolog 1(Drosophila)	0.353
Ednra	endothelin receptor type A	0.353
Tcf7	transcription factor 7, T-cell specific	0.337
Alx4	aristaless-like homeobox 4	0.328
Lhx5	LIM homeobox protein 5	0.293
Sox11	SRY-box containing gene 11	0.288
Sox1	SRY-box containing gene 1	0.267
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.263
Nanog	Nanog homeobox	0.252
Neurod1	neurogenic differentiation 1	0.243
Dlx5	distal-less homeobox 5	0.228
Tlx3	T-cell leukemia, homeobox 3	0.221
Wnt1	wingless-related MMTV integration site 1	0.214
Rarg	retinoic acid receptor, gamma	0.211
Emx2	empty spiracles homolog 2 (Drosophila)	0.205
Gbx2	gastrulation brain homeobox 2	0.204
Lhx1	LIM homeobox protein 1	0.202
Hes5	hairy and enhancer of split 5 (Drosophila)	0.202
Bdnf	brain derived neurotrophic factor	0.201
Chrd	chordin	0.180
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.176
Grid1	glutamate receptor, ionotropic, delta 1	0.175
Wnt7b	wingless-related MMTV integration site 7B	0.175
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.172
Plxna1	plexin A1	0.168
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.162
Gsc	goosecoid homeobox	0.159
Hoxa1	homeobox A1	0.159
Foxc1	forkhead box C1	0.153
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.149
Sox3	SRY-box containing gene 3	0.140
Kif5a	kinesin family member 5A	0.139
Dcc	deleted in colorectal carcinoma	0.132
Fgf4	fibroblast growth factor 4	0.130
Mgat3	mannoside acetylglucosaminyltransferase 3	0.128
Amh	anti-Mullerian hormone	0.127
Onecut1	one cut domain, family member 1	0.124
Pou3f3	POU domain, class 3, transcription factor 3	0.116	Mouse
Fgf15	fibroblast growth factor 15	0.116
Nog	noggin	0.116
Otx1	orthodenticle homolog 1 (Drosophila)	0.115
Efna2	ephrin A2	0.114
Foxd2	forkhead box D2	0.111
Dlx6	distal-less homeobox 6	0.111
En2	engrailed 2	0.107
Foxh1	forkhead box H1	0.105
Hmx1	H6 homeobox 1	0.101
Vangl2	vang-like 2 (van gogh, Drosophila)	0.101
Tbx10	T-box 10	0.096
Plxna3	plexin A3	0.094
Hoxb1	homeobox B1	0.094
Esrrb	estrogen related receptor, beta	0.093
Vax1	ventral anterior homeobox containing gene 1	0.092
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.090	Zebrafish
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.086
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.082
Zic4	zinc finger protein of the cerebellum 4	0.082
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.081
Drd2	dopamine receptor D2	0.080
Zic3	zinc finger protein of the cerebellum 3	0.080
Phox2a	paired-like homeobox 2a	0.080
Neurog2	neurogenin 2	0.080
Foxp2	forkhead box P2	0.079
AI118078	expressed sequence AI118078	0.078
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.078	Mouse
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.076
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.075
Etv2	ets variant gene 2	0.074
Bmp7	bone morphogenetic protein 7	0.072
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.072
Dlx1	distal-less homeobox 1	0.072
Sall1	sal-like 1 (Drosophila)	0.070
Atoh1	atonal homolog 1 (Drosophila)	0.070
Apc2	adenomatosis polyposis coli 2	0.070
Cdx1	caudal type homeobox 1	0.066
Sdc3	syndecan 3	0.066
Pnoc	prepronociceptin	0.063
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.062
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.062
Lmx1b	LIM homeobox transcription factor 1 beta	0.061
Mmp24	matrix metallopeptidase 24	0.061
Jag1	jagged 1	0.060
Tcfap2c	transcription factor AP-2, gamma	0.059
Uncx	UNC homeobox	0.056
Gdf11	growth differentiation factor 11	0.056
Dlg4	discs, large homolog 4 (Drosophila)	0.055
Cdh4	cadherin 4	0.055
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.054
Hes3	hairy and enhancer of split 3 (Drosophila)	0.054
Nhlh1	nescient helix loop helix 1	0.053
En1	engrailed 1	0.052
Neurog1	neurogenin 1	0.051
Dab1	disabled homolog 1 (Drosophila)	0.051
Lmx1a	LIM homeobox transcription factor 1 alpha	0.051
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.051
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.050
Axin2	axin2	0.049
Flt1	FMS-like tyrosine kinase 1	0.049
Pax8	paired box gene 8	0.048
Hoxd11	homeobox D11	0.048
Tbx1	T-box 1	0.047
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.046
C1ql1	complement component 1, q subcomponent-like 1	0.045
Lhx4	LIM homeobox protein 4	0.044
Evx2	even skipped homeotic gene 2 homolog	0.043
Prph2	peripherin 2	0.042
Bmp4	bone morphogenetic protein 4	0.041
Mef2b	myocyte enhancer factor 2B	0.041
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.041
Plekha7	pleckstrin homology domain containing, family A member 7	0.040
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.040
Robo3	roundabout homolog 3 (Drosophila)	0.039
Fgfr1	fibroblast growth factor receptor 1	0.039
Tcf15	transcription factor 15	0.038
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.038
Hist1h1t	histone cluster 1, H1t	0.037
Utf1	undifferentiated embryonic cell transcription factor 1	0.036
Cnr1	cannabinoid receptor 1 (brain)	0.035
Zscan2	zinc finger and SCAN domain containing 2	0.035
Hr	hairless	0.035
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.035
Ncs1	neuronal calcium sensor 1	0.035
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.035
Fgf17	fibroblast growth factor 17	0.034
Foxc2	forkhead box C2	0.034
T	brachyury	0.034
Hoxa11	homeobox A11	0.033
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.033
Foxb1	forkhead box B1	0.033
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.033
Ece1	endothelin converting enzyme 1	0.033
Wnt6	wingless-related MMTV integration site 6	0.032
Fgf5	fibroblast growth factor 5	0.032
Gpr44	G protein-coupled receptor 44	0.031
Phox2b	paired-like homeobox 2b	0.031
Foxk1	forkhead box K1	0.030
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.030
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.030
Tcfcp2l1	transcription factor CP2-like 1	0.030
Lhx9	LIM homeobox protein 9	0.030
Gdnf	glial cell line derived neurotrophic factor	0.029
Pitx1	paired-like homeodomain transcription factor 1	0.029
Rlbp1	retinaldehyde binding protein 1	0.029
Pla2g10	phospholipase A2, group X	0.029
Fgf18	fibroblast growth factor 18	0.029
Smo	smoothened homolog (Drosophila)	0.029
Onecut2	one cut domain, family member 2	0.029
Syt6	synaptotagmin VI	0.029
Bcl2	B-cell leukemia/lymphoma 2	0.029
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.029
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.028
Ina	internexin neuronal intermediate filament protein, alpha	0.028
Epha4	Eph receptor A4	0.028
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.028
Hoxb13	homeobox B13	0.028
Rax	retina and anterior neural fold homeobox	0.028	Mouse
Nodal	nodal	0.027
Nptx1	neuronal pentraxin 1	0.027
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.027
Scrt1	scratch homolog 1, zinc finger protein (Drosophila)	0.026
Hoxa2	homeobox A2	0.026
Ntf3	neurotrophin 3	0.026
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.026
Prkcc	protein kinase C, gamma	0.026
Plxna4	plexin A4	0.026
Dpysl4	dihydropyrimidinase-like 4	0.026
Prrx1	paired related homeobox 1	0.026
Hoxd13	homeobox D13	0.025
Gpr50	G-protein-coupled receptor 50	0.025
Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	0.025
BC024139	cDNA sequence BC024139	0.025
Wnt7a	wingless-related MMTV integration site 7A	0.025
Matn3	matrilin 3	0.024
Stra6	stimulated by retinoic acid gene 6	0.024
Neurog3	neurogenin 3	0.024
Cdh10	cadherin 10	0.024
Tead3	TEA domain family member 3	0.024
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.024
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.024	Mouse
Insr	insulin receptor	0.024
Fjx1	four jointed box 1 (Drosophila)	0.023
Acvr1	activin A receptor, type 1	0.023
Galr2	galanin receptor 2	0.023
Trh	thyrotropin releasing hormone	0.022
Foxf1a	forkhead box F1a	0.022
Fgf10	fibroblast growth factor 10	0.022
Msx3	homeobox, msh-like 3	0.022
Spry4	sprouty homolog 4 (Drosophila)	0.022
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.022
Pou3f4	POU domain, class 3, transcription factor 4	0.022	Mouse
Dll1	delta-like 1 (Drosophila)	0.022
Foxd1	forkhead box D1	0.022
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.021
Ybx2	Y box protein 2	0.021
Gjc1	gap junction protein, gamma 1	0.021
Tgfb2	transforming growth factor, beta 2	0.021
Gjb5	gap junction protein, beta 5	0.021
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.021
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.021
Tbx3	T-box 3	0.021
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.021
Fmnl1	formin-like 1	0.021
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.020
Gcm1	glial cells missing homolog 1 (Drosophila)	0.020
Unc5c	unc-5 homolog C (C. elegans)	0.020
Hoxa4	homeobox A4	0.020
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.020
Ebf3	early B-cell factor 3	0.020
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.020
Mesp1	mesoderm posterior 1	0.020
Dlx2	distal-less homeobox 2	0.019
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.019
Omp	olfactory marker protein	0.019
Avp	arginine vasopressin	0.019
Rimklb	ribosomal modification protein rimK-like family member B	0.019
Nkain1	Na+/K+ transporting ATPase interacting 1	0.019
Rdh10	retinol dehydrogenase 10 (all-trans)	0.019
Pcdh12	protocadherin 12	0.019
Rarb	retinoic acid receptor, beta	0.019
Otp	orthopedia homolog (Drosophila)	0.019
Gpr27	G protein-coupled receptor 27	0.018
Adra1b	adrenergic receptor, alpha 1b	0.018
Tlx2	T-cell leukemia, homeobox 2	0.018
Vegfa	vascular endothelial growth factor A	0.018
Wnt3	wingless-related MMTV integration site 3	0.018
Clip2	CAP-GLY domain containing linker protein 2	0.018
Glra1	glycine receptor, alpha 1 subunit	0.018
Sox10	SRY-box containing gene 10	0.018
Pou3f1	POU domain, class 3, transcription factor 1	0.018	Mouse
Oprd1	opioid receptor, delta 1	0.017
Srrm4	serine/arginine repetitive matrix 4	0.017
Cbln1	cerebellin 1 precursor protein	0.017
Rhox6	reproductive homeobox 6	0.017
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.017
Efnb2	ephrin B2	0.017
Fzd9	frizzled homolog 9 (Drosophila)	0.016
Lhx6	LIM homeobox protein 6	0.016
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.016
Gsx1	GS homeobox 1	0.016
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.016
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.016
Cckbr	cholecystokinin B receptor	0.016
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.016
Pou2f2	POU domain, class 2, transcription factor 2	0.015	Mouse
Nrtn	neurturin	0.015
Tead1	TEA domain family member 1	0.015
Zeb1	zinc finger E-box binding homeobox 1	0.015
Eomes	eomesodermin homolog (Xenopus laevis)	0.015
Ret	ret proto-oncogene	0.015
Sntb1	syntrophin, basic 1	0.015
Pou5f1	POU domain, class 5, transcription factor 1	0.015	Mouse
Plcb1	phospholipase C, beta 1	0.015
Clrn3	clarin 3	0.015
Col2a1	collagen, type II, alpha 1	0.015
Shd	src homology 2 domain-containing transforming protein D	0.015
Clcnka	chloride channel Ka	0.015
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.015
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.015
Theg	testicular haploid expressed gene	0.015
Zic1	zinc finger protein of the cerebellum 1	0.015
Fign	fidgetin	0.015
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.015
Zfp518b	zinc finger protein 518B	0.014
Pbx1	pre B-cell leukemia transcription factor 1	0.014
Prox1	prospero-related homeobox 1	0.014
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.014
Srcin1	SRC kinase signaling inhibitor 1	0.014
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.014
Igfbpl1	insulin-like growth factor binding protein-like 1	0.014
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.014
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.014
Kif5c	kinesin family member 5C	0.014
Hrh1	histamine receptor H1	0.014
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.014
Neurod4	neurogenic differentiation 4	0.014
Fzd6	frizzled homolog 6 (Drosophila)	0.014
Pdgfb	platelet derived growth factor, B polypeptide	0.014
Galr3	galanin receptor 3	0.014
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.014
Lhx2	LIM homeobox protein 2	0.014
Prop1	paired like homeodomain factor 1	0.014
Sox21	SRY-box containing gene 21	0.014
Lalba	lactalbumin, alpha	0.014
Nefm	neurofilament, medium polypeptide	0.013
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.013
Npas3	neuronal PAS domain protein 3	0.013
Tacr1	tachykinin receptor 1	0.013
Ptprs	protein tyrosine phosphatase, receptor type, S	0.013
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.013
Cryba1	crystallin, beta A1	0.013
Rtbdn	retbindin	0.013
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.013
Adam11	a disintegrin and metallopeptidase domain 11	0.013
Efna4	ephrin A4	0.013
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.013
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.013
BC057022	cDNA sequence BC057022	0.013
Sstr1	somatostatin receptor 1	0.013
Dcx	doublecortin	0.013
Cnih2	cornichon homolog 2 (Drosophila)	0.012
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.012
Sh3rf1	SH3 domain containing ring finger 1	0.012
Sox9	SRY-box containing gene 9	0.012
Ephb2	Eph receptor B2	0.012
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.012
Trim46	tripartite motif-containing 46	0.012
Gh	growth hormone	0.012
Neurod2	neurogenic differentiation 2	0.012
Hoxa13	homeobox A13	0.012
BC021785	cDNA sequence BC021785	0.012
Foxo4	forkhead box O4	0.012
Cdx2	caudal type homeobox 2	0.012
Id1	inhibitor of DNA binding 1	0.012
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.012
Efna3	ephrin A3	0.012
Fam59b	family with sequence similarity 59, member B	0.012
Alpl	alkaline phosphatase, liver/bone/kidney	0.012
Arl10	ADP-ribosylation factor-like 10	0.012
Ednrb	endothelin receptor type B	0.012
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.012
Pcdh18	protocadherin 18	0.012
Artn	artemin	0.011
Dll3	delta-like 3 (Drosophila)	0.011
Hes2	hairy and enhancer of split 2 (Drosophila)	0.011
Wiz	widely-interspaced zinc finger motifs	0.011
Hoxd12	homeobox D12	0.011
Hif3a	hypoxia inducible factor 3, alpha subunit	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.011
Tcfap2b	transcription factor AP-2 beta	0.011
Pppde2	PPPDE peptidase domain containing 2	0.011
2810046L04Rik	RIKEN cDNA 2810046L04 gene	0.011
Nppc	natriuretic peptide type C	0.011
Grb10	growth factor receptor bound protein 10	0.011
Calcr	calcitonin receptor	0.011
Irx1	Iroquois related homeobox 1 (Drosophila)	0.011
Plcg1	phospholipase C, gamma 1	0.011
Tulp1	tubby like protein 1	0.011
Mab21l2	mab-21-like 2 (C. elegans)	0.011
Npas1	neuronal PAS domain protein 1	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.011
Stra8	stimulated by retinoic acid gene 8	0.011
Cnga3	cyclic nucleotide gated channel alpha 3	0.010
Mdfi	MyoD family inhibitor	0.010
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.010
Grm8	glutamate receptor, metabotropic 8	0.010
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.010
Tgif2	TGFB-induced factor homeobox 2	0.010
Notch3	Notch gene homolog 3 (Drosophila)	0.010
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.010
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.010