IMP
Process View
positive regulation of cd4 positive alpha beta t cell activation
Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cd4 positive alpha beta t cell activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Csf2rb2 | colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) | 0.564 | Mouse | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.505 | ||
| Jak2 | Janus kinase 2 | 0.502 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.484 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.356 | ||
| Tnf | tumor necrosis factor | 0.343 | ||
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.334 | Mouse | |
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.293 | Mouse | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.281 | ||
| Lepr | leptin receptor | 0.229 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.206 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.195 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.186 | Mouse | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.168 | Mouse | |
| Ccl8 | chemokine (C-C motif) ligand 8 | 0.165 | ||
| Cish | cytokine inducible SH2-containing protein | 0.146 | Mouse | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.145 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.121 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.120 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.099 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.090 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.084 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.075 | ||
| Cd28 | CD28 antigen | 0.072 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.070 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.066 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.066 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.061 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.060 | Mouse | |
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.059 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.049 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.047 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.043 | Mouse | |
| Nfkbie | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.043 | ||
| Il6st | interleukin 6 signal transducer | 0.041 | ||
| Saa3 | serum amyloid A 3 | 0.041 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.040 | ||
| Ldb3 | LIM domain binding 3 | 0.038 | ||
| Foxp1 | forkhead box P1 | 0.037 | Mouse | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.036 | ||
| Icam1 | intercellular adhesion molecule 1 | 0.036 | ||
| Gzma | granzyme A | 0.036 | ||
| Runx1 | runt related transcription factor 1 | 0.035 | ||
| Il1b | interleukin 1 beta | 0.035 | ||
| 9430031J16Rik | RIKEN cDNA 9430031J16 gene | 0.035 | ||
| Ttc7 | tetratricopeptide repeat domain 7 | 0.035 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.035 | ||
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.034 | ||
| Cd40 | CD40 antigen | 0.034 | ||
| Cd44 | CD44 antigen | 0.034 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.034 | ||
| Msr1 | macrophage scavenger receptor 1 | 0.033 | ||
| Il7r | interleukin 7 receptor | 0.033 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.033 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.032 | ||
| Hcst | hematopoietic cell signal transducer | 0.031 | ||
| Prkce | protein kinase C, epsilon | 0.031 | ||
| Rarg | retinoic acid receptor, gamma | 0.030 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.029 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.028 | ||
| Cd86 | CD86 antigen | 0.027 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.027 | ||
| Ccl22 | chemokine (C-C motif) ligand 22 | 0.027 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.027 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.026 | ||
| Hhex | hematopoietically expressed homeobox | 0.026 | ||
| Socs2 | suppressor of cytokine signaling 2 | 0.024 | Mouse | |
| Tbxas1 | thromboxane A synthase 1, platelet | 0.024 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.024 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.023 | ||
| Gm11428 | predicted gene 11428 | 0.023 | ||
| Serpina3n | serine (or cysteine) peptidase inhibitor, clade A, member 3N | 0.022 | ||
| C3ar1 | complement component 3a receptor 1 | 0.022 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.021 | ||
| Irf5 | interferon regulatory factor 5 | 0.021 | ||
| Actn2 | actinin alpha 2 | 0.021 | ||
| Spna1 | spectrin alpha 1 | 0.021 | ||
| St3gal1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.020 | ||
| Itgax | integrin alpha X | 0.019 | ||
| Foxp3 | forkhead box P3 | 0.019 | ||
| Ctsw | cathepsin W | 0.019 | ||
| Rasal3 | RAS protein activator like 3 | 0.018 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.018 | ||
| Cul5 | cullin 5 | 0.017 | ||
| Foxp2 | forkhead box P2 | 0.017 | Mouse | |
| Ccl17 | chemokine (C-C motif) ligand 17 | 0.017 | Mouse | |
| Il2rb | interleukin 2 receptor, beta chain | 0.017 | ||
| Bcl2a1d | B-cell leukemia/lymphoma 2 related protein A1d | 0.016 | ||
| Clec4d | C-type lectin domain family 4, member d | 0.016 | ||
| Mmp3 | matrix metallopeptidase 3 | 0.016 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.015 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.015 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.015 | ||
| Jak3 | Janus kinase 3 | 0.015 | ||
| Has1 | hyaluronan synthase1 | 0.015 | ||
| Irg1 | immunoresponsive gene 1 | 0.015 | ||
| Lta | lymphotoxin A | 0.015 | ||
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.014 | ||
| Jak1 | Janus kinase 1 | 0.014 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.014 | ||
| Atf3 | activating transcription factor 3 | 0.014 | ||
| Abi1 | abl-interactor 1 | 0.014 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.014 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.014 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.013 | ||
| Pdcd1lg2 | programmed cell death 1 ligand 2 | 0.013 | ||
| Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.013 | ||
| Serpina3g | serine (or cysteine) peptidase inhibitor, clade A, member 3G | 0.013 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.013 | ||
| Il1r2 | interleukin 1 receptor, type II | 0.013 | ||
| Myo1g | myosin IG | 0.013 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.013 | ||
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.013 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.013 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.013 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.013 | ||
| Itgb2 | integrin beta 2 | 0.013 | ||
| Ifng | interferon gamma | 0.012 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.012 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.012 | ||
| Lcp2 | lymphocyte cytosolic protein 2 | 0.012 | ||
| Vav1 | vav 1 oncogene | 0.012 | ||
| Tnfrsf18 | tumor necrosis factor receptor superfamily, member 18 | 0.012 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.012 | ||
| Spred1 | sprouty protein with EVH-1 domain 1, related sequence | 0.012 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.012 | ||
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.012 | ||
| Dock2 | dedicator of cyto-kinesis 2 | 0.012 | ||
| Arid5a | AT rich interactive domain 5A (MRF1-like) | 0.012 | ||
| Nckap1l | NCK associated protein 1 like | 0.011 | ||
| Il6 | interleukin 6 | 0.011 | ||
| Tlr7 | toll-like receptor 7 | 0.011 | ||
| AI607873 | expressed sequence AI607873 | 0.011 | ||
| Lrrc33 | leucine rich repeat containing 33 | 0.011 | ||
| Fli1 | Friend leukemia integration 1 | 0.011 | ||
| Pim1 | proviral integration site 1 | 0.011 | ||
| Pfn2 | profilin 2 | 0.010 | ||
| Lyz2 | lysozyme 2 | 0.010 | ||
| Plek | pleckstrin | 0.010 | ||
| Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D | 0.010 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.010 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.010 | ||
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.010 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.010 | ||
| Il12b | interleukin 12b | 0.010 | ||
| Gp49a | glycoprotein 49 A | 0.010 | ||
| Rgs16 | regulator of G-protein signaling 16 | 0.010 |