IMP

Process View

Rattus norvegicus

4 genes annotated in rat

positive regulation of lipid catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of lipid catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of lipid catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Acot2	acyl-CoA thioesterase 2	0.300
Cd36	CD36 molecule (thrombospondin receptor)	0.175
Cpt2	carnitine palmitoyltransferase 2	0.139
Hist1h1a	histone cluster 1, H1a	0.136
Racgap1	Rac GTPase-activating protein 1	0.129
Prdm2	PR domain containing 2, with ZNF domain	0.108
Mcm6	minichromosome maintenance complex component 6	0.101
Top2a	topoisomerase (DNA) II alpha	0.091
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.089
Angptl4	angiopoietin-like 4	0.089
Mtus1	mitochondrial tumor suppressor 1	0.080
Cpt1b	carnitine palmitoyltransferase 1b, muscle	0.075	Rat
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.072
Cat	catalase	0.071
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	0.070
RGD1308772	similar to KIAA0564 protein	0.069
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.068
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.064
Camk2g	calcium/calmodulin-dependent protein kinase II gamma	0.062
Aqp7	aquaporin 7	0.058
Acadl	acyl-Coenzyme A dehydrogenase, long-chain	0.058
Tcfe2a	transcription factor E2a	0.057
Acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.056
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.056
Syngr2	synaptogyrin 2	0.051
Eci1	enoyl-Coenzyme A delta isomerase 1	0.051
Ghr	growth hormone receptor	0.051
Atp2b3	ATPase, Ca++ transporting, plasma membrane 3	0.047
Eps15	epidermal growth factor receptor pathway substrate 15	0.041
Hmgb2	high mobility group box 2	0.041
Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	0.039
Nfia	nuclear factor I/A	0.037
Traf4af1	TRAF4 associated factor 1	0.037
Stmn1	stathmin 1	0.036
Cidea	cell death-inducing DFFA-like effector a	0.035
Impa2	inositol (myo)-1(or 4)-monophosphatase 2	0.033
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.032
Snrk	SNF related kinase	0.032
Fgfr1	Fibroblast growth factor receptor 1	0.032
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.032
Amy2	amylase 2, pancreatic	0.032
Tff3	trefoil factor 3, intestinal	0.032
Dgat1	diacylglycerol O-acyltransferase homolog 1 (mouse)	0.031
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.031
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.031
Etfdh	electron-transferring-flavoprotein dehydrogenase	0.030
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.030
Ccne1	cyclin E1	0.030
Pttg1	pituitary tumor-transforming 1	0.029
Ccnd3	cyclin D3	0.028
Pbk	PDZ binding kinase	0.028
Vamp1	vesicle-associated membrane protein 1	0.028
Tbrg4	transforming growth factor beta regulator 4	0.028
Baat	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.027
Myo1c	myosin IC	0.026
Apoa2	apolipoprotein A-II	0.025
Nnt	nicotinamide nucleotide transhydrogenase	0.025
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.024
Ocln	occludin	0.024
Smc4	structural maintenance of chromosomes 4	0.023
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.023
Pcna	proliferating cell nuclear antigen	0.023
Prb1	proline-rich protein BstNI subfamily 1	0.023
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.023
Hbp1	HMG-box transcription factor 1	0.023
Tmem120a	transmembrane protein 120A	0.022
Ezr	ezrin	0.022
Rbp2	retinol binding protein 2, cellular	0.022
Lin7b	lin-7 homolog b (C. elegans)	0.021
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.021
Mki67	antigen identified by monoclonal antibody Ki-67	0.021
Cks2	CDC28 protein kinase regulatory subunit 2	0.021
Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.021
Cdkn3	cyclin-dependent kinase inhibitor 3	0.021
Pex11a	peroxisomal biogenesis factor 11 alpha	0.021
Acot1	acyl-CoA thioesterase 1	0.021
Casp3	caspase 3	0.021
Ryr2	ryanodine receptor 2, cardiac	0.021
Aifm3	apoptosis-inducing factor, mitochondrion-associated 3	0.020
Lipa	lipase A, lysosomal acid, cholesterol esterase	0.020
Mapt	microtubule-associated protein tau	0.020
Abcg4	ATP-binding cassette, subfamily G (WHITE), member 4	0.020
Bat5	HLA-B associated transcript 5	0.020
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.020
Pdia4	protein disulfide isomerase family A, member 4	0.020
Pnpla2	patatin-like phospholipase domain containing 2	0.020	Human
Alb	albumin	0.020
Agtr1a	angiotensin II receptor, type 1a	0.019
Cox8b	cytochrome c oxidase, subunit VIIIb	0.019
Mgll	monoglyceride lipase	0.019
Ephx2	epoxide hydrolase 2, cytoplasmic	0.019
Pex19	peroxisomal biogenesis factor 19	0.019
Ccnb1	cyclin B1	0.019
LOC259246	alpha-2u globulin PGCL1	0.019
Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha	0.019
Emp1	epithelial membrane protein 1	0.018
RGD1302996	hypothetical protein MGC:15854	0.018
Fn3k	fructosamine 3 kinase	0.018
Sdc1	syndecan 1	0.018
Prim1	DNA primase, p49 subunit	0.018
Inpp4b	inositol polyphosphate-4-phosphatase, type II	0.018
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.017
Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	0.017
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.017
Prkd3	protein kinase D3	0.017
Opcml	opioid binding protein/cell adhesion molecule-like	0.017
Rcbtb2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	0.017
Ns5atp9	NS5A (hepatitis C virus) transactivated protein 9	0.017
Apoa1	apolipoprotein A-I	0.017
Larp1b	La ribonucleoprotein domain family, member 1B	0.017
Fga	fibrinogen alpha chain	0.017
Ugt1a6	UDP glucuronosyltransferase 1 family, polypeptide A6	0.017
Atp13a2	ATPase type 13A2	0.016
Depdc1	DEP domain containing 1	0.016
Arf6	ADP-ribosylation factor 6	0.016
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.016
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.016
Ripk3	receptor-interacting serine-threonine kinase 3	0.016
Ube2c	ubiquitin-conjugating enzyme E2C	0.016
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.016
Casp6	caspase 6	0.016
Lenep	lens epithelial protein	0.016
LOC259245	alpha-2u globulin PGCL5	0.016
Itga7	integrin, alpha 7	0.016
Agxt2	alanine-glyoxylate aminotransferase 2	0.016
Ehd1	EH-domain containing 1	0.016
Tyms	thymidylate synthetase	0.016
Ech1	enoyl coenzyme A hydratase 1, peroxisomal	0.016
Fsd2	fibronectin type III and SPRY domain containing 2	0.016
Micalcl	MICAL C-terminal like	0.016
Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.016
LOC363331	similar to plasma membrane associated protein, S3-12	0.016
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.016
Pygl	phosphorylase, glycogen, liver	0.016
Adcy6	adenylate cyclase 6	0.016
Cblc	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.016
Cyp4f6	cytochrome P450, family 4, subfamily f, polypeptide 6	0.016
Pitx2	paired-like homeodomain 2	0.016
Aldob	aldolase B, fructose-bisphosphate	0.015
Mmd2	monocyte to macrophage differentiation-associated 2	0.015
Car3	carbonic anhydrase 3	0.015
Rpa2	replication protein A2	0.015
Pfkp	phosphofructokinase, platelet	0.015
Astn1	astrotactin 1	0.015
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.015
Narfl	nuclear prelamin A recognition factor-like	0.015
Amh	anti-Mullerian hormone	0.015
Clic4	chloride intracellular channel 4	0.015
RGD1560244	similar to hypothetical protein FLJ34512	0.015
Aurkb	aurora kinase B	0.015
Rdh7	retinol dehydrogenase 7	0.015
Csnk1d	casein kinase 1, delta	0.015
Pah	phenylalanine hydroxylase	0.015
RGD1306625	LOC360508	0.015
Casq1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.015
Fcgbpl1	Fc fragment of IgG binding protein-like 1	0.014
Pink1	PTEN induced putative kinase 1	0.014
Hand2	heart and neural crest derivatives expressed 2	0.014
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.014
Ect2	epithelial cell transforming sequence 2 oncogene	0.014
Lipe	lipase, hormone sensitive	0.014
Cdca3	cell division cycle associated 3	0.014
Tinag	tubulointerstitial nephritis antigen	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A	0.014
Kcnd2	potassium voltage-gated channel, Shal-related subfamily, member 2	0.014
Rrm2	ribonucleotide reductase M2	0.014
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.014
Stxbp3	syntaxin binding protein 3	0.014
Trrap	transformation/transcription domain-associated protein	0.014
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.014
Akap3	A kinase (PRKA) anchor protein 3	0.014
Mcm5	minichromosome maintenance complex component 5	0.014
Rnf43	ring finger protein 43	0.014
Tcf4	transcription factor 4	0.014
Btnl7	butyrophilin-like 7	0.014
Slc4a4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	0.014
Klkb1	kallikrein B, plasma 1	0.014
Rab9a	RAB9A, member RAS oncogene family	0.013
Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1	0.013
Hspb9	heat shock protein, alpha-crystallin-related, B9	0.013
Scn1a	sodium channel, voltage-gated, type I, alpha	0.013
Adck5	aarF domain containing kinase 5	0.013
Trip10	thyroid hormone receptor interactor 10	0.013
Gys2	glycogen synthase 2	0.013
Csrp3	cysteine and glycine-rich protein 3	0.013
Gclm	glutamate cysteine ligase, modifier subunit	0.013
Gper	G protein-coupled estrogen receptor 1	0.013
Slc24a6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	0.013
Wipf3	WAS/WASL interacting protein family, member 3	0.013
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.013
Glt25d1	glycosyltransferase 25 domain containing 1	0.013
Myh13	myosin, heavy chain 13, skeletal muscle	0.013
Fam111a	family with sequence similarity 111, member A	0.013
Ccna2	cyclin A2	0.013
Acaca	acetyl-coenzyme A carboxylase alpha	0.013
Pygm	phosphorylase, glycogen, muscle	0.013
Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.013
Actn2	actinin alpha 2	0.013
RGD1308742	similar to Complement C5 precursor	0.013
Adipoq	adiponectin, C1Q and collagen domain containing	0.013
Casp2	caspase 2	0.013
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.013
Megf8	multiple EGF-like-domains 8	0.013
Cpt1a	carnitine palmitoyltransferase 1a, liver	0.013
Mylk2	myosin light chain kinase 2	0.012
Prodh2	proline dehydrogenase (oxidase) 2	0.012
Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.012
Hebp1	heme binding protein 1	0.012
Acsl1	acyl-CoA synthetase long-chain family member 1	0.012	Rat
Plcb2	phospholipase C, beta 2	0.012
Cfc1	cripto, FRL-1, cryptic family 1	0.012
Akr1b8	aldo-keto reductase family 1, member B8	0.012
Crat	carnitine acetyltransferase	0.012	Rat
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.012
Impg1	interphotoreceptor matrix proteoglycan 1	0.012
Ces1e	carboxylesterase 1E	0.012
Amy1a	amylase, alpha 1A (salivary)	0.012
Asph	aspartate-beta-hydroxylase	0.012
RGD1564614	similar to complement factor H-related protein	0.012
Fabp7	fatty acid binding protein 7, brain	0.012
LOC290876	similar to RIKEN cDNA 1700029H14	0.012
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.012
Mcpt9	mast cell protease 9	0.012
Gsta5	glutathione S-transferase Yc2 subunit	0.012
Akap1	A kinase (PRKA) anchor protein 1	0.012
Lta4h	leukotriene A4 hydrolase	0.012
Ilvbl	ilvB (bacterial acetolactate synthase)-like	0.012
Pbsn	probasin	0.012
Car1	carbonic anhydrase 1	0.012
Notch2	Notch homolog 2 (Drosophila)	0.012
Hsdl2	hydroxysteroid dehydrogenase like 2	0.012
Fbp2	fructose-1,6-bisphosphatase 2	0.012
Caskin1	CASK interacting protein 1	0.012
Prcp	prolylcarboxypeptidase (angiotensinase C)	0.012
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.012
Tmem130	transmembrane protein 130	0.012
Epb49	erythrocyte membrane protein band 4.9 (dematin)	0.012
Btd	biotinidase	0.012
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.012
Snca	synuclein, alpha (non A4 component of amyloid precursor)	0.012
Klhl10	kelch-like 10 (Drosophila)	0.012
Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	0.012
Cox6a2	cytochrome c oxidase, subunit VIa, polypeptide 2	0.012
Chkb	choline kinase beta	0.012
Cidec	cell death-inducing DFFA-like effector c	0.012
Nfib	nuclear factor I/B	0.012
Ptbp1	polypyrimidine tract binding protein 1	0.012
Ank3	ankyrin 3, node of Ranvier	0.012
Anxa5	annexin A5	0.011
Lrrc39	leucine rich repeat containing 39	0.011
Pctp	phosphatidylcholine transfer protein	0.011
Gckr	glucokinase (hexokinase 4) regulator	0.011
Timp3	TIMP metallopeptidase inhibitor 3	0.011
Spdef	SAM pointed domain containing ets transcription factor	0.011
Proc	protein C	0.011
Pros1	protein S (alpha)	0.011
Dram2	DNA-damage regulated autophagy modulator 2	0.011
RGD1565787	similar to RIKEN cDNA 1810065E05	0.011
Lpl	lipoprotein lipase	0.011
Abp10	annexin V-binding protein ABP-10	0.011
Rbp7	retinol binding protein 7, cellular	0.011
Gipc3	GIPC PDZ domain containing family, member 3	0.011
Cyp39a1	cytochrome P450, family 39, subfamily a, polypeptide 1	0.011
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
Socs2	suppressor of cytokine signaling 2	0.011
Man2a2	mannosidase 2, alpha 2	0.011
Anxa11	annexin A11	0.011
Krtap1-5	keratin associated protein 1-5	0.011
Prp2l1	proline rich protein 2-like 1	0.011
Ucma	upper zone of growth plate and cartilage matrix associated	0.011
Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.011
Gpt	glutamic-pyruvate transaminase (alanine aminotransferase)	0.011
Klk1b21	kallikrein 1-related peptidase b21	0.011
Nusap1	nucleolar and spindle associated protein 1	0.011
RGD1310552	similar to hypothetical protein MGC38960	0.011
Tmpo	thymopoietin	0.011
Pter	phosphotriesterase related	0.011
RGD1564575	RGD1564575	0.011
LOC100361444	rCG31799-like	0.011
Npvf	neuropeptide VF precursor	0.011
Nrxn1	neurexin 1	0.011
Arhgap27	Rho GTPase activating protein 27	0.011
Kif16b	kinesin family member 16B	0.011
Bche	butyrylcholinesterase	0.011
LOC686841	similar to Protein EAN57	0.011
Ky	kyphoscoliosis peptidase	0.011
March11	membrane-associated ring finger (C3HC4) 11	0.011
Dll1	delta-like 1 (Drosophila)	0.011
Ung	uracil-DNA glycosylase	0.010
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.010
Lin7a	lin-7 homolog a (C. elegans)	0.010
Fignl1	fidgetin-like 1	0.010
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.010
Insig1	insulin induced gene 1	0.010
Adfp	adipose differentiation related protein	0.010
LOC100364919	hypothetical protein LOC100364919	0.010
Ak7	adenylate kinase 7	0.010
Lactb	lactamase, beta	0.010
Tbx5	T-box 5	0.010
Sepp1	selenoprotein P, plasma, 1	0.010
Usp2	ubiquitin specific peptidase 2	0.010
Opa1	optic atrophy 1 homolog (human)	0.010
Esrra	estrogen related receptor, alpha	0.010
Lgals8	lectin, galactoside-binding, soluble, 8	0.010
Rfxank	regulatory factor X-associated ankyrin-containing protein	0.010
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.010
Fabp1	fatty acid binding protein 1, liver	0.010
Tnip1	TNFAIP3 interacting protein 1	0.010
Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	0.010
Sptbn4	spectrin, beta, non-erythrocytic 4	0.010
Six1	SIX homeobox 1	0.010
Mcm2	minichromosome maintenance complex component 2	0.010
Hspa12a	heat shock protein 12A	0.010