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Process View

Danio rerio

14 genes annotated in zebrafish

dopaminergic neuron differentiation

The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dopaminergic neuron differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dopaminergic neuron differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
barhl2	BarH-like 2	0.980
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.952
sox2	SRY-box containing gene 2	0.723
pou3f1	POU class 3 homeobox 1	0.696
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.686	Mouse
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.685
sox3	SRY-box containing gene 3	0.658
dla	deltaA	0.642
foxp2	forkhead box P2	0.537
lhx5	LIM homeobox 5	0.501
nxph1	neurexophilin 1	0.456
ddc	dopa decarboxylase	0.433
fzd7b	frizzled homolog 7b	0.409
shha	sonic hedgehog a	0.401
otx1b	orthodenticle homolog 1b	0.399
dbx1a	developing brain homeobox 1a	0.344
lef1	lymphocyte enhancer binding factor 1	0.343
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.333
pitx3	paired-like homeodomain transcription factor 3	0.317	Mouse
dlx2a	distal-less homeobox gene 2a	0.312
fzd8a	frizzled homolog 8a	0.274
prox1	prospero-related homeobox gene 1	0.274
fezf2	FEZ family zinc finger 2	0.266
neurog1	neurogenin 1	0.261
hlx1	H2.0-like homeo box 1 (Drosophila)	0.227
gad1b	glutamate decarboxylase 1b	0.216
lhx1a	LIM homeobox 1a	0.215
dlb	deltaB	0.211
phox2a	paired-like homeobox 2a	0.210
bdnf	brain-derived neurotrophic factor	0.204
adcyap1b	adenylate cyclase activating polypeptide 1b	0.200
gfap	glial fibrillary acidic protein	0.188
efnb2a	ephrin B2a	0.182
emx2	empty spiracles homeobox 2	0.174
kal1a	Kallmann syndrome 1a sequence	0.163
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.151
atoh1a	atonal homolog 1a	0.149
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.146
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.145
nr4a2a	nuclear receptor subfamily 4, group A, member 2a	0.142
ccdc151	coiled-coil domain containing 151	0.142
nkx2.2a	NK2 transcription factor related 2a	0.119
nr4a1	nuclear receptor subfamily 4, group A, member 1	0.119	Zebrafish
dlx5a	distal-less homeobox gene 5a	0.098
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.094
met	met proto-oncogene (hepatocyte growth factor receptor)	0.094
hmgb1a	high-mobility group box 1a	0.091
tfap2b	transcription factor AP-2 beta	0.080
LOC555504	novel protocadherin protein	0.080
pcsk1nl	proprotein convertase subtilisin/kexin type 1 inhibitor, like	0.079
gata2a	GATA-binding protein 2a	0.078
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.074
otx2	orthodenticle homolog 2	0.070
zgc:103663	zgc:103663	0.069
zgc:110124	zgc:110124	0.067
mdkb	midkine-related growth factor b	0.066
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.065
mpz	myelin protein zero	0.065
robo2	roundabout homolog 2	0.063
atp2b1a	ATPase, Ca++ transporting, plasma membrane 1a	0.062
pcdh17	protocadherin 17	0.059
pvrl1b	poliovirus receptor-related 1b	0.059
crhbp	corticotropin releasing hormone binding protein	0.058
si:dkey-24g18.2	si:dkey-24g18.2	0.058
clock3	clock homolog 3 (mouse)	0.058
barhl1.1	BarH-like 1.1	0.055
otpa	orthopedia homolog a	0.055
mbp	myelin basic protein	0.055
wu:fi18a01	wu:fi18a01	0.054
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.054
xbp1	X-box binding protein 1	0.051
dld	deltaD	0.051
fabp7a	fatty acid binding protein 7, brain, a	0.051
her4.2	hairy-related 4.2	0.050
fzd7a	frizzled homolog 7a	0.049
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.049	Zebrafish
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.049
dlx1a	distal-less homeobox gene 1a	0.049
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.048
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.048
nf1b	neurofibromin 1b	0.047
lmo3	LIM domain only 3	0.046
adarb1	adenosine deaminase, RNA-specific, B1	0.046
gbx2	gastrulation brain homeo box 2	0.044
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.043
gria2a	glutamate receptor, ionotropic, AMPA 2a	0.042
slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.042
sst1.1	somatostatin 1, tandem duplicate 1	0.042
fgfr2	fibroblast growth factor receptor 2	0.041
gria4b	glutamate receptor, ionotropic, AMPA 4b	0.041
cx43	connexin 43	0.040
penka	proenkephalin a	0.039
otpb	orthopedia homolog b	0.039	Zebrafish
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.039
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.038
irx7	iroquois homeobox protein 7	0.037
pax7a	paired box gene 7a	0.037
tfap2a	transcription factor AP-2 alpha	0.037
lrrtm1	leucine rich repeat transmembrane neuronal 1	0.037
cry2b	cryptochrome 2b	0.037
emilin1a	elastin microfibril interfacer 1a	0.036
rx3	retinal homeobox gene 3	0.036
hmx3	homeo box (H6 family) 3	0.035
sox19a	SRY-box containing gene 19a	0.034
irx1b	iroquois homeobox protein 1, b	0.033
crh	corticotropin releasing hormone	0.033
zgc:101606	zgc:101606	0.033
sox11a	SRY-box containing gene 11a	0.032
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.031
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.031
tal1	T-cell acute lymphocytic leukemia 1	0.031
sall1a	sal-like 1a (Drosophila)	0.031
pink1	PTEN induced putative kinase 1	0.030
nrarpa	notch-regulated ankyrin repeat protein a	0.030
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.030
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.030
cnr1	cannabinoid receptor 1	0.029
LOC100331484	hypothetical protein LOC100331484	0.029
hhip	hedgehog interacting protein	0.029
zgc:101614	zgc:101614	0.029
camk2d2	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2	0.028
stmn4	stathmin-like 4	0.028
barhl1.2	BarH-like 1.2	0.027
rab3c	RAB3C, member RAS oncogene family	0.027
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.027
junb	jun B proto-oncogene	0.027
LOC569768	metabotropic glutamate receptor 8-like	0.027
kif5aa	kinesin family member 5A, a	0.027
meis2.2	myeloid ecotropic viral integration site 2.2	0.026
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.026
yap1	Yes-associated protein 1	0.026
nsfa	N-ethylmaleimide-sensitive factor a	0.026
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.026
kirrel3l	kin of IRRE like 3 like	0.026
grm5a	glutamate receptor, metabotropic 5a	0.025
sema6dl	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like	0.025
arx	aristaless related homeobox	0.025
fgf8a	fibroblast growth factor 8 a	0.024
sim1b	single-minded homolog 1b (Drosophila)	0.024	Zebrafish
dmbx1b	diencephalon/mesencephalon homeobox 1b	0.024
esrrga	estrogen-related receptor gamma a	0.024
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.024
sox10	SRY-box containing gene 10	0.024
tectb	tectorin beta	0.024
evx1	even-skipped homeobox 1	0.024
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.024
foxd3	forkhead box D3	0.023
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.023
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.023
nes	nestin	0.023
rorcb	RAR-related orphan receptor C b	0.023
pcdh7	protocadherin 7	0.023
olfm1b	olfactomedin 1b	0.023
irx5a	iroquois homeobox protein 5a	0.022
cadm4	cell adhesion molecule 4	0.022
col8a1a	collagen, type VIII, alpha 1a	0.022
foxb1.1	forkhead box B1.1	0.022
si:ch211-209p5.2	si:ch211-209p5.2	0.022
pcdh18a	protocadherin 18a	0.022
notch3	notch homolog 3	0.022
pcp4a	Purkinje cell protein 4a	0.021
dlx2b	distal-less homeobox gene 2b	0.021
olig2	oligodendrocyte lineage transcription factor 2	0.021
gpm6ab	glycoprotein M6Ab	0.021
helt	hey-like transcription factor	0.021
ebf3	early B-cell factor 3	0.021
nkx2.1b	NK2 homeobox 1b	0.021
tcf4	transcription factor 4	0.020
zgc:73142	zgc:73142	0.020
LOC556453	zinc finger homeobox protein 4-like	0.020
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.020
wtip	Wilms tumor 1 interacting protein	0.019
her6	hairy-related 6	0.019
sncgb	synuclein, gamma b (breast cancer-specific protein 1)	0.019
dlx6a	distal-less homeobox gene 6a	0.019
stmn2a	stathmin-like 2a	0.019
lhx6	LIM homeobox 6	0.019
pax6a	paired box gene 6a	0.019
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.019
stmn1b	stathmin 1b	0.019
slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.018
nadl1.2	neural adhesion molecule L1.2	0.018
znf503	zinc finger protein 503	0.018
chga	chromogranin A	0.018
thbs1	thrombospondin 1	0.018
copeb	core promoter element binding protein	0.018
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.017
gata3	GATA-binding protein 3	0.017
pcdh2ac	protocadherin 2 alpha c	0.017
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.017	Zebrafish
cdh23	cadherin-like 23	0.017
wu:fb17g07	wu:fb17g07	0.017
mecp2	methyl CpG binding protein 2	0.017
gpm6aa	glycoprotein M6Aa	0.017
gria3a	glutamate receptor, ionotropic, AMPA 3a	0.017
jag2	jagged 2	0.016
hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.016
LOC100007758	novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)	0.016
nr2f6b	nuclear receptor subfamily 2, group F, member 6b	0.016
lect1	leukocyte cell derived chemotaxin 1	0.016
prnprs3	prion protein, related sequence 3	0.016
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.016
igf2a	insulin-like growth factor 2a	0.015
ccnt2a	cyclin T2a	0.015
zgc:56538	zgc:56538	0.015
htr1bd	5-hydroxytryptamine (serotonin) receptor 1bd	0.015
ptf1a	pancreas specific transcription factor, 1a	0.015
snai2	snail homolog 2 (Drosophila)	0.015
lingo1b	leucine rich repeat and Ig domain containing 1b	0.015
grm1a	glutamate receptor, metabotropic 1a	0.015
cdh2	cadherin 2, neuronal	0.015
limk2	LIM domain kinase 2	0.014
neurod	neurogenic differentiation	0.014
her9	hairy-related 9	0.014
zgc:64114	zgc:64114	0.014
amigo1	adhesion molecule with Ig-like domain 1	0.014
dkk2	dickkopf homolog 2 (Xenopus laevis)	0.014
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.014
axin2	axin 2 (conductin, axil)	0.014
chrna6	cholinergic receptor, nicotinic, alpha 6	0.014
zic6	zic family member 6	0.014
arl4ab	ADP-ribosylation factor-like 4ab	0.013
sema3gb	semaphorin 3gb	0.013
gria2b	glutamate receptor, ionotropic, AMPA 2b	0.013
calb2b	calbindin 2b, (calretinin)	0.013
zgc:55582	zgc:55582	0.013
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.013
lhx2b	LIM homeobox 2b	0.013
eng2a	engrailed 2a	0.013
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.013
park7	parkinson disease (autosomal recessive, early onset) 7	0.013
fgf3	fibroblast growth factor 3	0.013
pdip5	protein disulfide isomerase-related protein (provisional)	0.013
cdh1	cadherin 1, epithelial	0.013
plxnb2a	plexin b2a	0.013
nf1a	neurofibromin 1a	0.013
LOC563527	brain-specific angiogenesis inhibitor 1-like	0.013
eya1	eyes absent homolog 1	0.013
adora2b	adenosine A2b receptor	0.012
dll4	delta-like 4 (Drosophila)	0.012
pde10a	phosphodiesterase 10A	0.012
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.012
ckbb	creatine kinase, brain b	0.012
LOC565256	similar to Metabotropic glutamate receptor 3 precursor (mGluR3)	0.012
neurod6b	neurogenic differentiation 6b	0.012
sh3gl2	SH3-domain GRB2-like 2	0.012
dlg2	discs, large (Drosophila) homolog 2	0.012
snap25a	synaptosome-associated protein 25a	0.011
slc25a25a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a	0.011
efna2	ephrin A2	0.011
bnc2	basonuclin 2	0.011
prkci	protein kinase C, iota	0.011
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
zgc:158603	zgc:158603	0.011
wu:fb71f10	wu:fb71f10	0.011
st8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.011
tuba1	tubulin, alpha 1	0.011
crabp1a	cellular retinoic acid binding protein 1a	0.011
eng2b	engrailed 2b	0.011
ntn1a	netrin 1a	0.011
dusp2	dual specificity phosphatase 2	0.011
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.011
polrmt	polymerase (RNA) mitochondrial (DNA directed)	0.011
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.011
vamp1	vesicle-associated membrane protein 1	0.011
calb2a	calbindin 2a	0.011
robo1	roundabout homolog 1	0.011
epha4a	eph receptor A4a	0.011
LOC565649	FYVE and coiled-coil domain-containing protein 1-like	0.010
hcrtr2	hypocretin (orexin) receptor 2	0.010
derl1	Der1-like domain family, member 1	0.010
ciz1	CDKN1A interacting zinc finger protein 1	0.010
lrrc4.1	leucine rich repeat containing 4.1	0.010
pou3f2	POU class 3 homeobox 2	0.010
gpr19	G protein-coupled receptor 19	0.010
junbl	jun B proto-oncogene, like	0.010
sox4a	SRY-box containing gene 4a	0.010