IMP
Process View
The network for 'regulation of interleukin 4 biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of interleukin 4 biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cd80 | CD80 antigen | 0.991 | |
| Pdcd1 | programmed cell death 1 | 0.892 | |
| Icos | inducible T-cell co-stimulator | 0.875 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.542 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.532 | |
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.274 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.235 | |
| Zbp1 | Z-DNA binding protein 1 | 0.227 | |
| Cd40 | CD40 antigen | 0.200 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.199 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.165 | |
| Rel | reticuloendotheliosis oncogene | 0.155 | |
| Ifng | interferon gamma | 0.149 | |
| Igh | immunoglobulin heavy chain complex | 0.115 | |
| Tbx21 | T-box 21 | 0.109 | |
| Il4 | interleukin 4 | 0.102 | |
| Rhoh | ras homolog gene family, member H | 0.100 | |
| Il2ra | interleukin 2 receptor, alpha chain | 0.096 | |
| Slamf7 | SLAM family member 7 | 0.091 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.091 | |
| Cd5 | CD5 antigen | 0.086 | |
| Irf8 | interferon regulatory factor 8 | 0.080 | |
| Gata1 | GATA binding protein 1 | 0.079 | |
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.073 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.066 | |
| Il21r | interleukin 21 receptor | 0.064 | |
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.064 | |
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.063 | |
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.059 | |
| Il10ra | interleukin 10 receptor, alpha | 0.057 | |
| Ubd | ubiquitin D | 0.057 | |
| Gpr33 | G protein-coupled receptor 33 | 0.052 | |
| Gbp1 | guanylate binding protein 1 | 0.050 | |
| Slamf8 | SLAM family member 8 | 0.050 | |
| Plek | pleckstrin | 0.049 | |
| Cd274 | CD274 antigen | 0.049 | |
| Il12rb1 | interleukin 12 receptor, beta 1 | 0.048 | |
| Itga4 | integrin alpha 4 | 0.045 | |
| Cd160 | CD160 antigen | 0.042 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.041 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.041 | |
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.041 | |
| Mta1 | metastasis associated 1 | 0.040 | |
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.040 | |
| Gbp7 | guanylate binding protein 7 | 0.039 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.039 | |
| Rgs1 | regulator of G-protein signaling 1 | 0.039 | |
| Lta | lymphotoxin A | 0.038 | |
| Cd6 | CD6 antigen | 0.038 | |
| Oas3 | 2'-5' oligoadenylate synthetase 3 | 0.036 | |
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.035 | |
| Il1r2 | interleukin 1 receptor, type II | 0.034 | |
| Lag3 | lymphocyte-activation gene 3 | 0.034 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.034 | |
| Bmp1 | bone morphogenetic protein 1 | 0.033 | |
| Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.033 | |
| Irg1 | immunoresponsive gene 1 | 0.032 | |
| Cd19 | CD19 antigen | 0.032 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.032 | |
| Mta2 | metastasis-associated gene family, member 2 | 0.032 | |
| Il27ra | interleukin 27 receptor, alpha | 0.031 | |
| Gcet2 | germinal center expressed transcript 2 | 0.031 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.031 | |
| Traf1 | TNF receptor-associated factor 1 | 0.030 | |
| Cxcr6 | chemokine (C-X-C motif) receptor 6 | 0.030 | |
| Cd180 | CD180 antigen | 0.029 | |
| Git1 | G protein-coupled receptor kinase-interactor 1 | 0.029 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.029 | |
| Cd8a | CD8 antigen, alpha chain | 0.029 | |
| Mobp | myelin-associated oligodendrocytic basic protein | 0.028 | |
| Irf5 | interferon regulatory factor 5 | 0.028 | |
| Ikzf3 | IKAROS family zinc finger 3 | 0.027 | |
| Cd72 | CD72 antigen | 0.026 | |
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.026 | |
| Sp110 | Sp110 nuclear body protein | 0.026 | |
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.026 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.026 | |
| Tnfrsf18 | tumor necrosis factor receptor superfamily, member 18 | 0.026 | |
| Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.025 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.025 | |
| Carm1 | coactivator-associated arginine methyltransferase 1 | 0.025 | |
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.025 | |
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.024 | |
| Cnga3 | cyclic nucleotide gated channel alpha 3 | 0.024 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.024 | |
| Itgal | integrin alpha L | 0.024 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.024 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.024 | |
| Gbp6 | guanylate binding protein 6 | 0.024 | |
| Mcoln2 | mucolipin 2 | 0.023 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.023 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.023 | |
| Tlr7 | toll-like receptor 7 | 0.022 | |
| Cd28 | CD28 antigen | 0.022 | |
| Myo1g | myosin IG | 0.021 | |
| Trim30d | tripartite motif-containing 30D | 0.021 | |
| Cd83 | CD83 antigen | 0.021 | |
| Pla2g2d | phospholipase A2, group IID | 0.021 | |
| Itk | IL2-inducible T-cell kinase | 0.020 | |
| Trim21 | tripartite motif-containing 21 | 0.019 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.178 | |
| IRF9 | interferon regulatory factor 9 | 0.053 | |
| IRF1 | interferon regulatory factor 1 | 0.051 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.036 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.033 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.030 | |
| IL15RA | interleukin 15 receptor, alpha | 0.026 | |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.023 | |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.021 | |
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 0.020 | |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.018 | |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.018 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.017 | |
| RBBP4 | retinoblastoma binding protein 4 | 0.015 | |
| ATG7 | ATG7 autophagy related 7 homolog (S. cerevisiae) | 0.012 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.011 | |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.011 | |
| IRF8 | interferon regulatory factor 8 | 0.010 |