The network for 'cardiac ventricle morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac ventricle morphogenesis

The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Pax2 paired box gene 2 1.000
Hand2 heart and neural crest derivatives expressed transcript 2 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Pitx2 paired-like homeodomain transcription factor 2 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.999
Notch1 Notch gene homolog 1 (Drosophila) 0.996
Isl1 ISL1 transcription factor, LIM/homeodomain 0.995
Gli3 GLI-Kruppel family member GLI3 0.993
Fgf8 fibroblast growth factor 8 0.993
Gata4 GATA binding protein 4 0.988
Foxc2 forkhead box C2 0.986
Foxg1 forkhead box G1 0.984
Pax3 paired box gene 3 0.984
Sox2 SRY-box containing gene 2 0.983
Sall4 sal-like 4 (Drosophila) 0.978
Hoxd13 homeobox D13 0.969
Ctnnb1 catenin (cadherin associated protein), beta 1 0.966
Chd7 chromodomain helicase DNA binding protein 7 0.966
Pax6 paired box gene 6 0.964
Hand1 heart and neural crest derivatives expressed transcript 1 0.963
Tbx1 T-box 1 0.959
Bmp4 bone morphogenetic protein 4 0.957
Foxh1 forkhead box H1 0.949
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.943
Lhx1 LIM homeobox protein 1 0.931
Meox2 mesenchyme homeobox 2 0.930
Nog noggin 0.927
Foxc1 forkhead box C1 0.919
Tlx3 T-cell leukemia, homeobox 3 0.911
Hoxa13 homeobox A13 0.906
Gbx2 gastrulation brain homeobox 2 0.906
Emx1 empty spiracles homolog 1 (Drosophila) 0.904
Tbx3 T-box 3 0.868
Tcfcp2l1 transcription factor CP2-like 1 0.861
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.860
Jag1 jagged 1 0.859
Eya1 eyes absent 1 homolog (Drosophila) 0.859
Emx2 empty spiracles homolog 2 (Drosophila) 0.858
Lmx1b LIM homeobox transcription factor 1 beta 0.853
Hoxa1 homeobox A1 0.849
Hoxd11 homeobox D11 0.840
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.833
Sox11 SRY-box containing gene 11 0.813
Efnb2 ephrin B2 0.809
Insm1 insulinoma-associated 1 0.808
Zeb1 zinc finger E-box binding homeobox 1 0.807
Pax8 paired box gene 8 0.806
Smad4 MAD homolog 4 (Drosophila) 0.798
Foxa2 forkhead box A2 0.787
Nodal nodal 0.786
Col1a1 collagen, type I, alpha 1 0.782
Gata6 GATA binding protein 6 0.782
Dll4 delta-like 4 (Drosophila) 0.771
Vangl2 vang-like 2 (van gogh, Drosophila) 0.770
Esrrb estrogen related receptor, beta 0.764
Gli2 GLI-Kruppel family member GLI2 0.755
Pthlh parathyroid hormone-like peptide 0.744
Pou4f2 POU domain, class 4, transcription factor 2 0.733
Rarg retinoic acid receptor, gamma 0.723
Smad6 MAD homolog 6 (Drosophila) 0.723
Fgf3 fibroblast growth factor 3 0.721
She src homology 2 domain-containing transforming protein E 0.712
Hes1 hairy and enhancer of split 1 (Drosophila) 0.703
Fgfr1 fibroblast growth factor receptor 1 0.690
Hmx3 H6 homeobox 3 0.686
Tcfap2a transcription factor AP-2, alpha 0.678
Pax1 paired box gene 1 0.675
Lmx1a LIM homeobox transcription factor 1 alpha 0.670
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.669
Tgfb2 transforming growth factor, beta 2 0.665
Sox18 SRY-box containing gene 18 0.664
Rxra retinoid X receptor alpha 0.658
Nos3 nitric oxide synthase 3, endothelial cell 0.653
En1 engrailed 1 0.649
Pitx1 paired-like homeodomain transcription factor 1 0.626
Atoh1 atonal homolog 1 (Drosophila) 0.600
Ptf1a pancreas specific transcription factor, 1a 0.573
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.550
Dlx2 distal-less homeobox 2 0.542
Hes5 hairy and enhancer of split 5 (Drosophila) 0.540
Uncx UNC homeobox 0.528
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.516
Hoxd3 homeobox D3 0.516
Pou3f3 POU domain, class 3, transcription factor 3 0.512
Nkx2-1 NK2 homeobox 1 0.504
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.502
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.501
Otx1 orthodenticle homolog 1 (Drosophila) 0.486
Lhx3 LIM homeobox protein 3 0.478
Zic3 zinc finger protein of the cerebellum 3 0.476
Sox3 SRY-box containing gene 3 0.468
Hoxa10 homeobox A10 0.463
Neurod4 neurogenic differentiation 4 0.458
Myl3 myosin, light polypeptide 3 0.450
Fgfr3 fibroblast growth factor receptor 3 0.450
Gdf5 growth differentiation factor 5 0.442
Neurog2 neurogenin 2 0.441
Axin1 axin 1 0.439
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.897
mef2cb myocyte enhancer factor 2cb 0.642
myod1 myogenic differentiation 1 0.539
tal1 T-cell acute lymphocytic leukemia 1 0.425
tbx5a T-box 5a 0.346
hnf1ba HNF1 homeobox Ba 0.293
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.281
tnnt2a troponin T2a, cardiac 0.265
tnni1b troponin I, skeletal, slow b 0.242
gata5 GATA-binding protein 5 0.232
tnnt3b troponin T3b, skeletal, fast 0.207
ttna titin a 0.195
smyhc1 slow myosin heavy chain 1 0.193
smyhc1l slow myosin heavy chain 1, like 0.183
smyd1b SET and MYND domain containing 1b 0.177
rbm24a RNA binding motif protein 24a 0.175
gpr126 G protein-coupled receptor 126 0.118
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.110
actn3b actinin alpha 3b 0.109
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.102
notch3 notch homolog 3 0.094
tnni1al troponin I, skeletal, slow like 0.092
etv2 ets variant gene 2 0.092
tnnt3a troponin T3a, skeletal, fast 0.090
gata2a GATA-binding protein 2a 0.085
znf148 zinc finger protein 148 0.078
tbx20 T-box 20 0.076
wnt11r wingless-type MMTV integration site family, member 11, related 0.070
hhex hematopoietically expressed homeobox 0.067
aplnrb apelin receptor b 0.066
vmhc ventricular myosin heavy chain 0.065
smyhc2 slow myosin heavy chain 2 0.065
tnnc1b troponin C type 1b (slow) 0.064
nkx2.5 NK2 transcription factor related 5 0.064
tnnc2 troponin C type 2 (fast) 0.062
wls wntless homolog (Drosophila) 0.059
actc1a actin, alpha, cardiac muscle 1a 0.059
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.059
tmem88a transmembrane protein 88 a 0.054
wif1 wnt inhibitory factor 1 0.054
isl1 islet1 0.053
ckma creatine kinase, muscle a 0.052
col5a1 procollagen, type V, alpha 1 0.050
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.050
cdh2 cadherin 2, neuronal 0.048
tnni2a.4 troponin I, skeletal, fast 2a.4 0.047
spon1b spondin 1b 0.042
col11a1b collagen type XI alpha-1b and collagen, type XI, alpha 1b 0.042
cmlc1 cardiac myosin light chain-1 0.041
pcdh10b protocadherin 10b 0.040
bmp2b bone morphogenetic protein 2b 0.040
alcama activated leukocyte cell adhesion molecule a 0.039
bmp4 bone morphogenetic protein 4 0.038
foxi1 forkhead box I1 0.037
edn1 endothelin 1 0.037
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.036
pld1a phospholipase D1a 0.033
pdlim7 PDZ and LIM domain 7 0.033
flt4 fms-related tyrosine kinase 4 0.033
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.032
foxc1a forkhead box C1a 0.030
tmem2 transmembrane protein 2 0.030
fn1 fibronectin 1 0.030
mybpc3 myosin binding protein C, cardiac 0.029
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.029
ogg1 8-oxoguanine DNA glycosylase 0.028
has2 hyaluronan synthase 2 0.027
jag1b jagged 1b 0.026
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.026
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.025
kdrl kinase insert domain receptor like 0.025
unc45b unc-45 homolog B (C. elegans) 0.024
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.024
mib mind bomb 0.023
dlx4b distal-less homeobox gene 4b 0.023
fgf18a fibroblast growth factor 18a 0.023
myl7 myosin, light polypeptide 7, regulatory 0.021
lmo2 LIM domain only 2 (rhombotin-like 1) 0.021
hand2 heart and neural crest derivatives expressed transcript 2 0.020
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.020
oep one-eyed pinhead 0.019
tpma alpha-tropomyosin 0.019
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.018
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.018
dzip1 DAZ interacting protein 1 0.018
coro1b coronin, actin binding protein, 1B 0.017
cx36.7 connexin 36.7 0.017
tln1 talin 1 0.016
hmx2 H6 family homeobox 2 0.016
eya4 eyes absent homolog 4 (Drosophila) 0.015
sulf2l sulfatase 2, like 0.015
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.014
bmp3 bone morphogenetic protein 3 0.014
nppa natriuretic peptide precursor A 0.014
ccm2 cerebral cavernous malformation 2 0.014
myl1 myosin, light chain 1, alkali; skeletal, fast 0.013
pax6b paired box gene 6b 0.013
igfbp3 insulin-like growth factor binding protein 3 0.013
snf8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.013
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.013
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TNNC1 troponin C type 1 (slow) 1.000
TNNI1 troponin I type 1 (skeletal, slow) 0.998
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.983
TPM1 tropomyosin 1 (alpha) 0.964
NOTCH1 notch 1 0.860
EP300 E1A binding protein p300 0.833
NOTCH3 notch 3 0.827
SMYD1 SET and MYND domain containing 1 0.818
TBX5 T-box 5 0.796
TNNT2 troponin T type 2 (cardiac) 0.754
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.708
NCOA1 nuclear receptor coactivator 1 0.699
MED25 mediator complex subunit 25 0.694
TNNI2 troponin I type 2 (skeletal, fast) 0.647
TPM2 tropomyosin 2 (beta) 0.607
CKM creatine kinase, muscle 0.581
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.549
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.530
HAP1 huntingtin-associated protein 1 0.509
ACTA1 actin, alpha 1, skeletal muscle 0.507
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.496
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.469
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.423
SMAD9 SMAD family member 9 0.392
SFN stratifin 0.384
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.355
DSP desmoplakin 0.350
ESR1 estrogen receptor 1 0.324
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.322
LDB3 LIM domain binding 3 0.321
TNNT1 troponin T type 1 (skeletal, slow) 0.310
ACVR1B activin A receptor, type IB 0.305
TNNT3 troponin T type 3 (skeletal, fast) 0.302
FGF10 fibroblast growth factor 10 0.292
MYOD1 myogenic differentiation 1 0.284
TRIM63 tripartite motif containing 63 0.265
GATA4 GATA binding protein 4 0.257
MYH9 myosin, heavy chain 9, non-muscle 0.238
KRT14 keratin 14 0.235
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.234
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.227
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.223
PDLIM7 PDZ and LIM domain 7 (enigma) 0.208
JUP junction plakoglobin 0.193
TNNC2 troponin C type 2 (fast) 0.188
DES desmin 0.187
GATA2 GATA binding protein 2 0.178
FGF1 fibroblast growth factor 1 (acidic) 0.170
MYBPC2 myosin binding protein C, fast type 0.167
VCP valosin containing protein 0.161
HNF4A hepatocyte nuclear factor 4, alpha 0.160
JAG1 jagged 1 0.150
ESR2 estrogen receptor 2 (ER beta) 0.148
GSK3B glycogen synthase kinase 3 beta 0.130
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.127
HEYL hairy/enhancer-of-split related with YRPW motif-like 0.120
SMAD3 SMAD family member 3 0.119
CXXC5 CXXC finger protein 5 0.116
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.115
RARA retinoic acid receptor, alpha 0.110
CTBP2 C-terminal binding protein 2 0.108
ACTN3 actinin, alpha 3 0.103
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.098
RB1 retinoblastoma 1 0.097
KAT2B K(lysine) acetyltransferase 2B 0.096
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.092
KRT8 keratin 8 0.091
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.091
TAL1 T-cell acute lymphocytic leukemia 1 0.089
MYBPC1 myosin binding protein C, slow type 0.087
ACTC1 actin, alpha, cardiac muscle 1 0.082
TGFBR1 transforming growth factor, beta receptor 1 0.080
PSEN1 presenilin 1 0.079
PKP2 plakophilin 2 0.074
ARNT aryl hydrocarbon receptor nuclear translocator 0.071
TNS4 tensin 4 0.070
MYL12B myosin, light chain 12B, regulatory 0.068
EPAS1 endothelial PAS domain protein 1 0.068
PTPRJ protein tyrosine phosphatase, receptor type, J 0.064
PAX8 paired box 8 0.062
AKAP12 A kinase (PRKA) anchor protein 12 0.061
MAML1 mastermind-like 1 (Drosophila) 0.060
HIPK2 homeodomain interacting protein kinase 2 0.060
RIPK3 receptor-interacting serine-threonine kinase 3 0.059
SOX11 SRY (sex determining region Y)-box 11 0.058
CORO1C coronin, actin binding protein, 1C 0.056
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.053
ACTN2 actinin, alpha 2 0.052
SOX7 SRY (sex determining region Y)-box 7 0.048
CCK cholecystokinin 0.046
PDE4DIP phosphodiesterase 4D interacting protein 0.046
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.046
SMAD2 SMAD family member 2 0.044
FLNA filamin A, alpha 0.043
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.043
NSFL1C NSFL1 (p97) cofactor (p47) 0.041
NOTCH2 notch 2 0.040
PML promyelocytic leukemia 0.039
DSG2 desmoglein 2 0.038
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.038
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism