The network for 'cyclic purine nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cyclic purine nucleotide metabolic process

The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.

Name Description Probability Func Analog Organism
Drd2 dopamine receptor D2 0.995
Ar androgen receptor 0.990
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.975
Esr1 estrogen receptor 1 (alpha) 0.966
Lepr leptin receptor 0.937
Pgr progesterone receptor 0.922
Cckbr cholecystokinin B receptor 0.912
Lep leptin 0.905
Pten phosphatase and tensin homolog 0.883
Nos3 nitric oxide synthase 3, endothelial cell 0.809
Kl klotho 0.743
Ghr growth hormone receptor 0.723
Pparg peroxisome proliferator activated receptor gamma 0.704
Pnpla2 patatin-like phospholipase domain containing 2 0.684
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.672
Sstr4 somatostatin receptor 4 0.650
Thra thyroid hormone receptor alpha 0.648
Crhr1 corticotropin releasing hormone receptor 1 0.611
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.562
Kit kit oncogene 0.548
Oprm1 opioid receptor, mu 1 0.537
Shc3 src homology 2 domain-containing transforming protein C3 0.497
Tac2 tachykinin 2 0.497
Ctnnb1 catenin (cadherin associated protein), beta 1 0.490
Nos1 nitric oxide synthase 1, neuronal 0.457
Amhr2 anti-Mullerian hormone type 2 receptor 0.448
Prlr prolactin receptor 0.441
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.436
Pomc pro-opiomelanocortin-alpha 0.421
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.420
Adra2a adrenergic receptor, alpha 2a 0.414
Insr insulin receptor 0.405
Adrb1 adrenergic receptor, beta 1 0.401
Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide 0.400
Adora2a adenosine A2a receptor 0.397
Rho rhodopsin 0.380
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.369
Npc1 Niemann Pick type C1 0.366
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.347
Pax8 paired box gene 8 0.324
Cav1 caveolin 1, caveolae protein 0.318
Acvrl1 activin A receptor, type II-like 1 0.318
Npy1r neuropeptide Y receptor Y1 0.307
Tshr thyroid stimulating hormone receptor 0.306
Thrb thyroid hormone receptor beta 0.293
Pthlh parathyroid hormone-like peptide 0.287
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.279
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.270
Rgs9 regulator of G-protein signaling 9 0.258
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.255
Wnt2b wingless related MMTV integration site 2b 0.239
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.230
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.229
Apc adenomatosis polyposis coli 0.212
Nppb natriuretic peptide type B 0.207
Edn1 endothelin 1 0.199
Cntn4 contactin 4 0.197
Grid1 glutamate receptor, ionotropic, delta 1 0.191
Fxyd7 FXYD domain-containing ion transport regulator 7 0.186
Esr2 estrogen receptor 2 (beta) 0.178
Mc5r melanocortin 5 receptor 0.177
Ednrb endothelin receptor type B 0.177
Nxph2 neurexophilin 2 0.176
Foxi3 forkhead box I3 0.176
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.176
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.175
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.173
Sstr2 somatostatin receptor 2 0.170
Oprk1 opioid receptor, kappa 1 0.166
Esrrb estrogen related receptor, beta 0.166
Sstr1 somatostatin receptor 1 0.162
Npy2r neuropeptide Y receptor Y2 0.161
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.160
Lrp1 low density lipoprotein receptor-related protein 1 0.155
Prop1 paired like homeodomain factor 1 0.155
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.154
Prkar1b protein kinase, cAMP dependent regulatory, type I beta 0.152
Inha inhibin alpha 0.152
Aatk apoptosis-associated tyrosine kinase 0.151
Bglap bone gamma carboxyglutamate protein 0.149
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.148
Tcfcp2l1 transcription factor CP2-like 1 0.147
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.146
Edil3 EGF-like repeats and discoidin I-like domains 3 0.145
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.144
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.144
Vdr vitamin D receptor 0.144
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.141
Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 0.139
Galr1 galanin receptor 1 0.132
Adra1a adrenergic receptor, alpha 1a 0.131
Nhedc2 Na+/H+ exchanger domain containing 2 0.130
Hand1 heart and neural crest derivatives expressed transcript 1 0.130
Tpbpa trophoblast specific protein alpha 0.129
Adrb2 adrenergic receptor, beta 2 0.126
Sntb1 syntrophin, basic 1 0.125
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 0.124
Nrg3 neuregulin 3 0.119
a nonagouti 0.118
Osta organic solute transporter alpha 0.117
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
daf-11 Protein DAF-11 0.372
tax-4 Protein TAX-4 0.314
odr-3 Protein ODR-3 0.206
E02A10.3 Protein E02A10.3 0.124
gcy-22 Protein GCY-22 0.087
tax-2 Protein TAX-2 0.068
oig-1 Protein OIG-1 0.064
pkg-1 Protein PKG-1 0.049
dbl-1 Protein DBL-1 0.047
che-1 Protein CHE-1 0.046
osm-3 Protein OSM-3 0.045
cal-4 Protein CAL-4 0.043
tag-147 Protein TAG-147 0.042
F53F10.2 Protein F53F10.2 0.039
pde-4 Protein PDE-4 0.036
sol-1 Protein SOL-1 0.035
F52C12.4 Protein F52C12.4 0.032
gcy-6 Protein GCY-6 0.031
CELE_M176.5 Protein M176.5 0.030
pry-1 Protein PRY-1 0.030
che-3 Protein CHE-3 0.026
C01H6.3 Protein C01H6.3 0.026
T19D2.3 Protein T19D2.3 0.025
F07C3.2 Protein F07C3.2 0.025
ser-2 Protein SER-2 0.024
sago-1 Protein SAGO-1 0.024
odr-1 Protein ODR-1 0.024
F46C5.2 Protein F46C5.2 0.024
F16B4.5 Protein F16B4.5 0.024
Y70D2A.1 Protein Y70D2A.1 0.023
CELE_T28B8.3 Protein T28B8.3 0.023
daf-7 Protein DAF-7 0.022
sri-11 Protein SRI-11 0.021
ser-3 Protein SER-3 0.021
srr-3 Protein SRR-3 0.021
K08E4.4 Protein K08E4.4 0.021
str-8 Protein STR-8 0.020
T05H10.8 Protein T05H10.8 0.019
Y72A10A.1 Protein Y72A10A.1 0.019
unc-43 Protein UNC-43 0.019
ser-7 Protein SER-7 0.019
F46H5.7 Protein F46H5.7 0.018
ser-4 Protein SER-4 0.018
C53A5.9 Protein C53A5.9 0.017
sng-1 Protein SNG-1 0.017
ZC317.2 Protein ZC317.2 0.017
T01G6.1 Protein T01G6.1 0.017
F01G12.6 Protein F01G12.6 0.017
prl-1 Protein PRL-1 0.017
che-2 Protein CHE-2 0.016
R03G8.3 Protein R03G8.3 0.016
srx-16 Protein SRX-16 0.016
R03G5.3 Protein R03G5.3 0.016
C25E10.11 Protein C25E10.11 0.016
inx-19 Protein INX-19 0.016
F59B8.1 Protein F59B8.1 0.016
T09B9.2 Protein T09B9.2 0.016
CELE_K03H1.5 Protein K03H1.5 0.016
ncr-2 Protein NCR-2 0.016
C37C3.11 Protein C37C3.11 0.016
CELE_Y64G10A.6 Protein Y64G10A.6 0.015
clec-179 Protein CLEC-179 0.015
F53A2.1 Protein F53A2.1 0.015
C06E7.2 Protein C06E7.2 0.015
str-193 Protein STR-193 0.015
glr-4 Protein GLR-4 0.015
T07H6.4 Protein T07H6.4 0.015
K08C7.6 Protein K08C7.6 0.015
CELE_F33E2.6 Protein F33E2.6 0.015
C04F12.8 Protein C04F12.8 0.015
col-105 Protein COL-105 0.015
unc-79 Protein UNC-79 0.014
CELE_C08H9.13 Protein C08H9.13 0.014
casy-1 Protein CASY-1 0.014
R10H10.4 Protein R10H10.4 0.014
srbc-22 Protein SRBC-22 0.014
lpin-1 Protein LPIN-1 0.014
math-41 Protein MATH-41 0.014
srab-14 Protein SRAB-14 0.014
kvs-2 Protein KVS-2 0.014
R05G6.5 Protein R05G6.5 0.014
lron-6 Protein LRON-6 0.014
T28B4.4 Protein T28B4.4 0.014
exc-7 Protein EXC-7 0.014
C18B2.1 Protein C18B2.1 0.014
CELE_Y105E8A.24 Protein Y105E8A.24 0.014
ztf-26 Protein ZTF-26 0.014
acr-2 Protein ACR-2 0.013
F40A3.7 Protein F40A3.7 0.013
rskn-2 Protein RSKN-2 0.013
frm-1 Protein FRM-1 0.013
acr-15 Protein ACR-15 0.013
tom-1 Protein TOM-1 0.013
Y110A2AL.5 Protein Y110A2AL.5 0.013
csp-2 Protein CSP-2 0.013
Y49A3A.4 Protein Y49A3A.4 0.013
C31H1.7 Protein C31H1.7 0.013
sulp-7 Protein SULP-7 0.013
CELE_F52E1.9 Protein F52E1.9 0.013
M01H9.2 Protein M01H9.2 0.013
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
uts1 urotensin 1 0.947
avpl arginine vasopressin-like 0.944
mc4r melanocortin 4 receptor 0.870
adra2b adrenergic, alpha-2B-, receptor 0.816
mc2r melanocortin 2 receptor 0.810
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.772
drd3 dopamine receptor D3 0.707
drd2b dopamine receptor D2b 0.551
adrb2a adrenergic receptor, beta 2a 0.506
ucn3l urocortin 3, like 0.476
vipr2 vasoactive intestinal peptide receptor 2 0.461
sst3 somatostatin 3 0.450
adra2db adrenergic, alpha-2D-, receptor b 0.403
drd2a dopamine receptor D2a 0.347
oprd1a opioid receptor, delta 1a 0.301
rtn1a reticulon 1a 0.298
mc1r melanocortin 1 receptor 0.267
mc3r melanocortin 3 receptor 0.266
adrb1 adrenergic receptor, beta 1 0.240
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.223
rhag Rhesus blood group-associated glycoprotein 0.212
oxtl oxytocin-like 0.209
uts2b urotensin 2, beta 0.209
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.204
mchr1a melanin-concentrating hormone receptor 1a 0.192
inhbab inhibin, beta Ab 0.155
dbh dopamine beta hydroxylase 0.153
hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.148
cx55.5 connexin 55.5 0.144
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.137
chrnb3b cholinergic receptor, nicotinic, beta polypeptide 3b 0.132
crygs2 crystallin, gamma S2 0.131
adra2c adrenergic, alpha-2C-, receptor 0.130
opn4l opsin 4, like 0.129
pdca phosducin a 0.112
paqr8 progestin and adipoQ receptor family member VIII 0.110
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.109
cldn2 claudin 2 0.105
bmp8a bone morphogenetic protein 8a 0.098
npy4r neuropeptide Y receptor Y4 0.097
ptpra protein tyrosine phosphatase, receptor type, A 0.097
mpp5b membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b) 0.094
mc5rb melanocortin 5b receptor 0.094
mchr1b melanin-concentrating hormone receptor 1b 0.093
LOC569642 hypothetical protein LOC569642 0.092
drd2l dopamine receptor D2 like 0.092
adcyap1r1a adenylate cyclase activating polypeptide 1 receptor 1a 0.092
adra2da adrenergic, alpha-2D-, receptor a 0.089
alx4a aristaless-like homeobox 4a 0.088
chrm2a cholinergic receptor, muscarinic 2a 0.088
gucy2f guanylate cyclase 2F, retinal 0.087
fgfrl1b fibroblast growth factor receptor-like 1b 0.087
adipoql adiponectin, C1Q and collagen domain containing, like 0.083
th2 tyrosine hydroxylase 2 0.080
npy8br neuropeptide Y receptor Y8b 0.077
LOC569128 hypothetical protein LOC569128 0.074
or115-10 odorant receptor, family F, subfamily 115, member 10 0.072
calm1a calmodulin 1a 0.069
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.068
guca1c guanylate cyclase activator 1C 0.068
rag1 recombination activating gene 1 0.068
cart1 cartilage paired-class homeoprotein 1 0.066
kif5c kinesin family member 5C 0.063
mstnb myostatin b 0.063
cps1 carbamoyl-phosphate synthase 1, mitochondrial 0.061
gdnf glial cell derived neurotrophic factor 0.060
hdc histidine decarboxylase 0.060
adra2a adrenergic, alpha-2A-, receptor 0.059
slc8a4b solute carrier family 8 (sodium/calcium exchanger), member 4b 0.059
si:rp71-40n14.1 si:rp71-40n14.1 0.057
flj13639 flj13639 0.055
palm paralemmin 0.055
dclk2 doublecortin-like kinase 2 0.054
hcrtr2 hypocretin (orexin) receptor 2 0.053
grk7a G-protein-coupled receptor kinase 7a 0.053
si:ch211-14k19.8 si:ch211-14k19.8 0.053
gc2 guanylyl cyclase 2 0.053
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.051
gnrh2 gonadotropin-releasing hormone 2 0.051
LOC555482 tachykinin receptor 3-like 0.051
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.050
mtnr1ba melatonin receptor type 1B a 0.049
gfra1b gdnf family receptor alpha 1b 0.048
pp pyrophosphatase (inorganic) 0.048
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.048
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.047
pnrc2 proline-rich nuclear receptor coactivator 2 0.046
nt5e 5'-nucleotidase, ecto (CD73) 0.046
cnr1 cannabinoid receptor 1 0.046
prkcea protein kinase C, epsilon a 0.046
mc5ra melanocortin 5a receptor 0.044
opn1mw4 opsin 1 (cone pigments), medium-wave-sensitive, 4 0.044
msi2a musashi homolog 2a (Drosophila) 0.043
c1qtnf4 C1q and tumor necrosis factor related protein 4 0.043
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.042
gsdf gonadal somatic cell derived factor 0.042
saga S-antigen; retina and pineal gland (arrestin) a 0.042
valopa vertebrate ancient long opsin a 0.041
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.041
fermt2 fermitin family homolog 2 (Drosophila) 0.041
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Tbh Tyramine beta hydroxylase 0.817
Pde8 Phosphodiesterase 8 0.772
CG42629 CG42629 gene product from transcript CG42629-RB 0.701
foxo forkhead box, sub-group O 0.692
dnc dunce 0.690
wit wishful thinking 0.586
Gyc-89Db Guanylyl cyclase at 89Db 0.570
CG13253 CG13253 gene product from transcript CG13253-RB 0.547
Shaw Shaker cognate w 0.502
Atf-2 Activating transcription factor-2 0.458
CaMKII Calcium/calmodulin-dependent protein kinase II 0.422
Gyc-89Da Guanylyl cyclase at 89Da 0.368
tim timeless 0.355
Nrx-1 Neurexin 1 0.336
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.282
Actbeta Activin-beta 0.279
Nmdar1 NMDA receptor 1 0.266
CG14686 CG14686 gene product from transcript CG14686-RA 0.246
amon amontillado 0.233
Cng Cyclic-nucleotide-gated ion channel protein 0.229
king-tubby king tubby 0.214
5-HT1B Serotonin receptor 1B 0.208
G-salpha60A G protein salpha 60A 0.193
CG34400 CG34400 gene product from transcript CG34400-RD 0.139
Mst57Db Male-specific RNA 57Db 0.137
mtt mangetout 0.135
tau CG31057 gene product from transcript CG31057-RA 0.135
Dsk Drosulfakinin 0.132
5-HT1A Serotonin receptor 1A 0.122
Frq2 Frequenin 2 0.121
slo slowpoke 0.121
dnr1 defense repressor 1 0.114
Plc21C Phospholipase C at 21C 0.108
CG31919 CG31919 gene product from transcript CG31919-RC 0.108
pdfr PDF receptor 0.104
Ank2 Ankyrin 2 0.099
CG32813 CG32813 gene product from transcript CG32813-RE 0.090
5-HT7 Serotonin receptor 7 0.089
G-oalpha47A G protein oalpha 47A 0.088
mGluRA metabotropic glutamate receptor 0.085
Dyb Dystrobrevin-like 0.085
Ric Ras which interacts with Calmodulin 0.084
GABA-B-R2 metabotropic GABA-B receptor subtype 2 0.080
Gr33a Gustatory receptor 33a 0.075
Gr64e Gustatory receptor 64e 0.070
rtGEF rho-type guanine exchange factor 0.066
jeb jelly belly 0.066
oa2 octopamine receptor 2 0.064
CG16778 CG16778 gene product from transcript CG16778-RA 0.062
unc-13 CG2999 gene product from transcript CG2999-RA 0.060
CG42574 CG42574 gene product from transcript CG42574-RE 0.058
CG31191 CG31191 gene product from transcript CG31191-RA 0.056
Eip63F-1 Ecdysone-induced protein 63F 1 0.055
Vmat Vesicular monoamine transporter 0.055
CG11155 CG11155 gene product from transcript CG11155-RA 0.053
rpr reaper 0.053
neuroligin CG13772 gene product from transcript CG13772-RA 0.053
CG34353 CG34353 gene product from transcript CG34353-RA 0.051
klg klingon 0.050
pain painless 0.050
Dh Diuretic hormone 0.049
cry cryptochrome 0.048
Clk Clock 0.046
Nf1 Neurofibromin 1 0.043
nord CG30418 gene product from transcript CG30418-RA 0.041
CG8959 CG8959 gene product from transcript CG8959-RA 0.039
fd85E forkhead domain 85E 0.038
CG6983 CG6983 gene product from transcript CG6983-RA 0.038
CG33203 CG33203 gene product from transcript CG33203-RB 0.036
GluRIIB Glutamate receptor IIB 0.035
to takeout 0.033
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.032
moody CG4322 gene product from transcript CG4322-RD 0.032
CG32778 CG32778 gene product from transcript CG32778-RA 0.031
Eaat2 Excitatory amino acid transporter 2 0.030
CG31146 CG31146 gene product from transcript CG31146-RD 0.029
pHCl CG33989 gene product from transcript CG33989-RD 0.029
CG4239 CG4239 gene product from transcript CG4239-RA 0.029
CdsA CDP diglyceride synthetase 0.029
CG17107 CG17107 gene product from transcript CG17107-RA 0.028
Rheb CG1081 gene product from transcript CG1081-RA 0.028
CG15088 CG15088 gene product from transcript CG15088-RC 0.028
NPFR1 neuropeptide F receptor 0.027
Fer2 48 related 2 0.026
Sox100B CG15552 gene product from transcript CG15552-RA 0.025
dpr20 CG12191 gene product from transcript CG12191-RA 0.025
CG8481 CG8481 gene product from transcript CG8481-RB 0.025
CG6282 CG6282 gene product from transcript CG6282-RC 0.025
uzip unzipped 0.025
myoglianin CG1838 gene product from transcript CG1838-RD 0.025
eys eyes shut 0.025
Ast-C Allatostatin C 0.024
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.024
Ac78C Adenylyl cyclase 78C 0.024
CYLD cylindromatosis 0.024
inaE inactivation no afterpotential E 0.024
beta4GalNAcTA CG8536 gene product from transcript CG8536-RA 0.023
SK small conductance calcium-activated potassium channel 0.023
CG15529 CG15529 gene product from transcript CG15529-RA 0.023
CG3009 CG3009 gene product from transcript CG3009-RA 0.023
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.000
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.000
PDZD3 PDZ domain containing 3 0.987
GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) 0.986
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.984
FHL1 four and a half LIM domains 1 0.980
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.958
ARRB1 arrestin, beta 1 0.947
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.932
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.890
CRHR1 corticotropin releasing hormone receptor 1 0.871
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.867
TBXA2R thromboxane A2 receptor 0.865
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.855
CRH corticotropin releasing hormone 0.852
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.826
TBC1D10A TBC1 domain family, member 10A 0.809
MT1A metallothionein 1A 0.805
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.793
NME3 non-metastatic cells 3, protein expressed in 0.734
NOSTRIN nitric oxide synthase trafficker 0.671
HP haptoglobin 0.668
MAPT microtubule-associated protein tau 0.624
MPDZ multiple PDZ domain protein 0.595
PDZK1 PDZ domain containing 1 0.525
CLDN5 claudin 5 0.492
SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.490
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.456
VAC14 Vac14 homolog (S. cerevisiae) 0.430
CALCRL calcitonin receptor-like 0.424
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.420
A2M alpha-2-macroglobulin 0.412
GOPC golgi-associated PDZ and coiled-coil motif containing 0.404
RGS20 regulator of G-protein signaling 20 0.399
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.385
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.379
DRD2 dopamine receptor D2 0.377
PRDX4 peroxiredoxin 4 0.357
ADRB2 adrenergic, beta-2-, receptor, surface 0.350
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.323
MEOX2 mesenchyme homeobox 2 0.320
CD34 CD34 molecule 0.307
PDE4DIP phosphodiesterase 4D interacting protein 0.294
RALBP1 ralA binding protein 1 0.285
GPR6 G protein-coupled receptor 6 0.269
ADORA2A adenosine A2a receptor 0.258
DEAF1 deformed epidermal autoregulatory factor 1 (Drosophila) 0.249
GHRHR growth hormone releasing hormone receptor 0.247
RIN1 Ras and Rab interactor 1 0.245
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.236
NCOA2 nuclear receptor coactivator 2 0.235
PTEN phosphatase and tensin homolog 0.227
STX5 syntaxin 5 0.224
LCAT lecithin-cholesterol acyltransferase 0.217
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.212
PTH1R parathyroid hormone 1 receptor 0.206
CXCR5 chemokine (C-X-C motif) receptor 5 0.201
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.200
APOC3 apolipoprotein C-III 0.200
RALGDS ral guanine nucleotide dissociation stimulator 0.192
NCF2 neutrophil cytosolic factor 2 0.191
EGFL7 EGF-like-domain, multiple 7 0.175
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.169
SRCIN1 SRC kinase signaling inhibitor 1 0.167
HTR4 5-hydroxytryptamine (serotonin) receptor 4 0.167
ADORA1 adenosine A1 receptor 0.166
APOC1 apolipoprotein C-I 0.165
BZW1 basic leucine zipper and W2 domains 1 0.158
FYN FYN oncogene related to SRC, FGR, YES 0.156
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.154
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.153
BCR breakpoint cluster region 0.152
ACHE acetylcholinesterase 0.151
PDCD6IP programmed cell death 6 interacting protein 0.146
EZR ezrin 0.145
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C 0.142
ADRA2A adrenergic, alpha-2A-, receptor 0.136
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.134
DNM1 dynamin 1 0.134
CALCA calcitonin-related polypeptide alpha 0.121
KCTD17 potassium channel tetramerisation domain containing 17 0.121
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.120
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.120
WDYHV1 WDYHV motif containing 1 0.119
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.117
FGA fibrinogen alpha chain 0.116
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.116
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B 0.115
SLC5A5 solute carrier family 5 (sodium iodide symporter), member 5 0.115
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.114
GFAP glial fibrillary acidic protein 0.113
MTNR1A melatonin receptor 1A 0.110
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.110
DTX2 deltex homolog 2 (Drosophila) 0.108
ADRB3 adrenergic, beta-3-, receptor 0.107
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.106
AFF2 AF4/FMR2 family, member 2 0.106
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.105
RET ret proto-oncogene 0.105
NSF N-ethylmaleimide-sensitive factor 0.104
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Rattus norvegicus
Name Description Probability Func Analog Organism
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.558
Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2 0.519
Olr416 olfactory receptor 416 0.431
Dlg4 discs, large homolog 4 (Drosophila) 0.377
Drd2 dopamine receptor D2 0.339
Dynll1 dynein light chain LC8-type 1 0.311
Fgf14 fibroblast growth factor 14 0.294
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.293
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.264
Odf4 outer dense fiber of sperm tails 4 0.259
Cacna1i calcium channel, voltage-dependent, T type, alpha 1I subunit 0.250
Sstr5 somatostatin receptor 5 0.224
Cyss cystatin S 0.222
Hrh3 histamine receptor H3 0.203
Aqp2 aquaporin 2 (collecting duct) 0.198
Grik3 glutamate receptor, ionotropic, kainate 3 0.197
Notch3 Notch homolog 3 (Drosophila) 0.192
Gpr1 G protein-coupled receptor 1 0.191
Prp15 proline-rich protein 15 0.190
Crhr1 corticotropin releasing hormone receptor 1 0.186
Nme1 non-metastatic cells 1, protein (NM23A) expressed in 0.185
Vipr2 vasoactive intestinal peptide receptor 2 0.182
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.177
Ube2d4 ubiquitin-conjugating enzyme E2D 4 0.176
Gpr6 G protein-coupled receptor 6 0.171
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.165
Adora1 adenosine A1 receptor 0.164
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.163
Kctd13 potassium channel tetramerisation domain containing 13 0.155
RGD1308165 similar to hypothetical protein MGC17337 0.150
Impg2 interphotoreceptor matrix proteoglycan 2 0.149
Ncan neurocan 0.147
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.147
Hcrt hypocretin 0.147
Syt7 synaptotagmin VII 0.145
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.137
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.136
Smr3a submaxillary gland androgen regulated protein 3A 0.132
Chat choline acetyltransferase 0.125
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.125
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.124
Clstn3 calsyntenin 3 0.124
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.123
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.121
Hpca hippocalcin 0.119
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.118
Cmklr1 chemokine-like receptor 1 0.114
Acrv1 acrosomal vesicle protein 1 0.111
Gabra2 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 0.110
Zg16 zymogen granule protein 16 0.109
Calcrl calcitonin receptor-like 0.108
Rho rhodopsin 0.108
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.108
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.106
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.104
Atp1a4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.099
Pgam1 phosphoglycerate mutase 1 (brain) 0.099
Avpr1b arginine vasopressin receptor 1B 0.099
Csf1 colony stimulating factor 1 (macrophage) 0.099
Epn2 epsin 2 0.098
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.098
Ifitm3 interferon induced transmembrane protein 3 0.097
Sema4f sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.097
LOC60591 calcium-activated potassium channel beta subunit 0.095
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.094
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.094
Olr287 olfactory receptor 287 0.093
Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) 0.091
Ptp4a2 protein tyrosine phosphatase 4a2 0.089
Rorb RAR-related orphan receptor B 0.089
Adrb1 adrenergic, beta-1-, receptor 0.089
Csf3 colony stimulating factor 3 (granulocyte) 0.088
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.087
Cd63 Cd63 molecule 0.087
Accn3 amiloride-sensitive cation channel 3 0.087
Ocm oncomodulin 0.084
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.083
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.082
Strn striatin, calmodulin binding protein 0.082
Accn2 amiloride-sensitive cation channel 2, neuronal 0.082
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.080
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.080
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.079
Ton tonin 0.078
Prdm2 PR domain containing 2, with ZNF domain 0.078
Cxcr5 chemokine (C-X-C motif) receptor 5 0.077
Cd79b Cd79b molecule, immunoglobulin-associated beta 0.077
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.075
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.075
Ddn dendrin 0.075
Grk1 G protein-coupled receptor kinase 1 0.073
Calca calcitonin-related polypeptide alpha 0.073
Cacng8 calcium channel, voltage-dependent, gamma subunit 8 0.072
Svs1 seminal vesicle secretory protein 1 0.072
Rph3a rabphilin 3A 0.072
Cacng6 calcium channel, voltage-dependent, gamma subunit 6 0.071
Lamb2 laminin, beta 2 0.071
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.071
Map6 microtubule-associated protein 6 0.071
Oxtr oxytocin receptor 0.070
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism