IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of nitric oxide synthase biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of nitric oxide synthase biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of nitric oxide synthase biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.996	Human
VEGFA	vascular endothelial growth factor A	0.944
MAP2K4	mitogen-activated protein kinase kinase 4	0.847	Rat
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.782
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.741	Human
LAT	linker for activation of T cells	0.716
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.670
MAPK8	mitogen-activated protein kinase 8	0.662
MAPK14	mitogen-activated protein kinase 14	0.582
CAV1	caveolin 1, caveolae protein, 22kDa	0.568
BCAR1	breast cancer anti-estrogen resistance 1	0.462
EGFR	epidermal growth factor receptor	0.453
PDGFA	platelet-derived growth factor alpha polypeptide	0.443
SOS1	son of sevenless homolog 1 (Drosophila)	0.433
MAPK9	mitogen-activated protein kinase 9	0.371	Rat
ND1	NADH dehydrogenase, subunit 1 (complex I)	0.362
PLCG1	phospholipase C, gamma 1	0.353
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.316
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.295
XPO7	exportin 7	0.283
INSR	insulin receptor	0.277
CDH5	cadherin 5, type 2 (vascular endothelium)	0.251
IFNGR1	interferon gamma receptor 1	0.213
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.190
NRP1	neuropilin 1	0.181
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.169
LRRK2	leucine-rich repeat kinase 2	0.151
PDGFC	platelet derived growth factor C	0.146
PGF	placental growth factor	0.135
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.134
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.132
PTPRB	protein tyrosine phosphatase, receptor type, B	0.129
LY96	lymphocyte antigen 96	0.108
GAB1	GRB2-associated binding protein 1	0.096
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.090
GHR	growth hormone receptor	0.089
SOCS1	suppressor of cytokine signaling 1	0.089
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.088	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.080
MAPK1	mitogen-activated protein kinase 1	0.073
ARRB1	arrestin, beta 1	0.063
KITLG	KIT ligand	0.062
STAT5A	signal transducer and activator of transcription 5A	0.058
TICAM2	toll-like receptor adaptor molecule 2	0.057
GAB2	GRB2-associated binding protein 2	0.053
EHD1	EH-domain containing 1	0.051
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.050
TAOK2	TAO kinase 2	0.050
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.050
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.047
SOS2	son of sevenless homolog 2 (Drosophila)	0.045
FYN	FYN oncogene related to SRC, FGR, YES	0.042
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.041
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.040
IGF1R	insulin-like growth factor 1 receptor	0.039
FGFR1	fibroblast growth factor receptor 1	0.038
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.033
ATF2	activating transcription factor 2	0.032
CLEC4E	C-type lectin domain family 4, member E	0.032	Human
LDLR	low density lipoprotein receptor	0.031
CLEC4D	C-type lectin domain family 4, member D	0.031	Human
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.031
FTL	ferritin, light polypeptide	0.031
KIAA1712	KIAA1712	0.030
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.029
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.029
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.027
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.026
MAP2K6	mitogen-activated protein kinase kinase 6	0.026	Rat
SLA	Src-like-adaptor	0.025
GOLGA7	golgin A7	0.025
ARRB2	arrestin, beta 2	0.025
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.023
FYB	FYN binding protein	0.023
PRKCQ	protein kinase C, theta	0.023
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.023
FLT4	fms-related tyrosine kinase 4	0.022	Human
CMIP	c-Maf-inducing protein	0.022
JAK2	Janus kinase 2	0.022	Mouse Rat
CAB39	calcium binding protein 39	0.020
SOD2	superoxide dismutase 2, mitochondrial	0.020
ZBTB25	zinc finger and BTB domain containing 25	0.020
MAP2	microtubule-associated protein 2	0.019
IRS1	insulin receptor substrate 1	0.019
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.018
FTH1	ferritin, heavy polypeptide 1	0.018
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.018
IL1R1	interleukin 1 receptor, type I	0.018
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.018
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.017
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.017
MAP2K7	mitogen-activated protein kinase kinase 7	0.017
ARHGAP32	Rho GTPase activating protein 32	0.017
ASGR1	asialoglycoprotein receptor 1	0.017
SYK	spleen tyrosine kinase	0.017
TGFB3	transforming growth factor, beta 3	0.017
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.016
AXL	AXL receptor tyrosine kinase	0.016
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.016
CCR2	chemokine (C-C motif) receptor 2	0.016
PTEN	phosphatase and tensin homolog	0.015
ADORA2A	adenosine A2a receptor	0.015
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.015
IL1B	interleukin 1, beta	0.015
COL1A1	collagen, type I, alpha 1	0.015
FAS	Fas (TNF receptor superfamily, member 6)	0.015
MAPT	microtubule-associated protein tau	0.015
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.014
CYBB	cytochrome b-245, beta polypeptide	0.014
MAPK3	mitogen-activated protein kinase 3	0.013
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.013
SOCS3	suppressor of cytokine signaling 3	0.013
IGSF6	immunoglobulin superfamily, member 6	0.013
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.013
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.013
GGPS1	geranylgeranyl diphosphate synthase 1	0.013
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.013
SH2D1A	SH2 domain containing 1A	0.012
PITPNA	phosphatidylinositol transfer protein, alpha	0.012
TLR1	toll-like receptor 1	0.012
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.012
IL1R2	interleukin 1 receptor, type II	0.012
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.012
RHOU	ras homolog gene family, member U	0.012
CLEC5A	C-type lectin domain family 5, member A	0.012
PTPRE	protein tyrosine phosphatase, receptor type, E	0.012
SH2B2	SH2B adaptor protein 2	0.011
IL8	interleukin 8	0.011
STAT2	signal transducer and activator of transcription 2, 113kDa	0.011
TLR3	toll-like receptor 3	0.011
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.011
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.011
DUSP7	dual specificity phosphatase 7	0.011
EPOR	erythropoietin receptor	0.011
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.011
CD33	CD33 molecule	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.010
ANGPT2	angiopoietin 2	0.010
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.010
TEK	TEK tyrosine kinase, endothelial	0.010
CCL20	chemokine (C-C motif) ligand 20	0.010	Rat
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.010	Human
PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	0.010