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Homo sapiens

24 genes annotated in human

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regulation of epithelial cell differentiation

GO:0030856

Any process that modulates the frequency, rate or extent of epithelial cell differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of epithelial cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of epithelial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
SFN	stratifin	0.729	Mouse
BBS10	Bardet-Biedl syndrome 10	0.538
NRP1	neuropilin 1	0.502
TJP1	tight junction protein 1 (zona occludens 1)	0.427
CDK6	cyclin-dependent kinase 6	0.426
VEGFA	vascular endothelial growth factor A	0.415	Mouse
RARA	retinoic acid receptor, alpha	0.378
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.343
BMPR1A	bone morphogenetic protein receptor, type IA	0.321
KRT5	keratin 5	0.315
RUNX1	runt-related transcription factor 1	0.285
NCOR2	nuclear receptor corepressor 2	0.283
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.253
SMAD2	SMAD family member 2	0.248
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.246
EP300	E1A binding protein p300	0.216
NCOR1	nuclear receptor corepressor 1	0.214
CCNE1	cyclin E1	0.209
SMAD4	SMAD family member 4	0.206
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.193
CREBBP	CREB binding protein	0.183
JAG1	jagged 1	0.159
GSK3B	glycogen synthase kinase 3 beta	0.134
ZMYND11	zinc finger, MYND-type containing 11	0.133
HOXB5	homeobox B5	0.127	Human
AR	androgen receptor	0.102
RXRA	retinoid X receptor, alpha	0.101
ESR1	estrogen receptor 1	0.099
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.094
CLOCK	clock homolog (mouse)	0.092	Mouse
SRSF4	serine/arginine-rich splicing factor 4	0.090	Human
NRIP1	nuclear receptor interacting protein 1	0.085
HOXA10	homeobox A10	0.082
HOXA7	homeobox A7	0.079
RB1	retinoblastoma 1	0.075
HOXB9	homeobox B9	0.075
EGFR	epidermal growth factor receptor	0.075
NCOA1	nuclear receptor coactivator 1	0.075	Human
HOXA11	homeobox A11	0.075
NOTCH3	notch 3	0.073
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.070
CDH5	cadherin 5, type 2 (vascular endothelium)	0.070
SRSF6	serine/arginine-rich splicing factor 6	0.068
NOTCH1	notch 1	0.063	Mouse Rat
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.063
FOXO1	forkhead box O1	0.063
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.062	Mouse
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.060
SMAD7	SMAD family member 7	0.059
INSR	insulin receptor	0.058
CTBP1	C-terminal binding protein 1	0.056
NKX2-1	NK2 homeobox 1	0.056
GJA1	gap junction protein, alpha 1, 43kDa	0.055
GRB10	growth factor receptor-bound protein 10	0.053
HNF4A	hepatocyte nuclear factor 4, alpha	0.052
GATA2	GATA binding protein 2	0.051
NCOA2	nuclear receptor coactivator 2	0.051	Human
TJP2	tight junction protein 2 (zona occludens 2)	0.049
SUFU	suppressor of fused homolog (Drosophila)	0.048
HOXB7	homeobox B7	0.047	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.046	Mouse
SMAD1	SMAD family member 1	0.044
AKAP11	A kinase (PRKA) anchor protein 11	0.042
TCF4	transcription factor 4	0.042
STK36	serine/threonine kinase 36	0.041
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.041
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.041
HOXC10	homeobox C10	0.040
FSTL1	follistatin-like 1	0.040
MSX1	msh homeobox 1	0.038
STAT5A	signal transducer and activator of transcription 5A	0.038	Mouse
ZNF746	zinc finger protein 746	0.037
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.037
TGIF1	TGFB-induced factor homeobox 1	0.037
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.037
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.036
NDP	Norrie disease (pseudoglioma)	0.036
TCF12	transcription factor 12	0.035
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.035
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.034
ESR2	estrogen receptor 2 (ER beta)	0.034
KANK2	KN motif and ankyrin repeat domains 2	0.034
HOXB6	homeobox B6	0.034	Human
CCND3	cyclin D3	0.032
E2F1	E2F transcription factor 1	0.032
CABLES1	Cdk5 and Abl enzyme substrate 1	0.032
HOXA5	homeobox A5	0.032	Human
LAD1	ladinin 1	0.031
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.030
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.029
CNOT8	CCR4-NOT transcription complex, subunit 8	0.029
HOXA2	homeobox A2	0.029
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.028	Mouse
WNT3A	wingless-type MMTV integration site family, member 3A	0.028
OCLN	occludin	0.028
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.027
PKP3	plakophilin 3	0.027
CDCA5	cell division cycle associated 5	0.027
HOXB3	homeobox B3	0.027
WNT5A	wingless-type MMTV integration site family, member 5A	0.027
EPAS1	endothelial PAS domain protein 1	0.026
NME4	non-metastatic cells 4, protein expressed in	0.026
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.026
SP1	Sp1 transcription factor	0.026
PGR	progesterone receptor	0.026
NOTCH2	notch 2	0.025
BMP4	bone morphogenetic protein 4	0.024
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.024
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.024
ARRB1	arrestin, beta 1	0.023
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.023
POU5F1	POU class 5 homeobox 1	0.023
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.023
CDX2	caudal type homeobox 2	0.023
BAD	BCL2-associated agonist of cell death	0.022
PTK2	PTK2 protein tyrosine kinase 2	0.022
PGF	placental growth factor	0.022
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.022
SATB2	SATB homeobox 2	0.021
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.021
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.021
C16orf53	chromosome 16 open reading frame 53	0.021
BCAR1	breast cancer anti-estrogen resistance 1	0.020
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.020
HDAC4	histone deacetylase 4	0.020
HOXC6	homeobox C6	0.020	Human
HOXC5	homeobox C5	0.019	Human
TGFB1	transforming growth factor, beta 1	0.019
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.018
TNS4	tensin 4	0.018
STAP2	signal transducing adaptor family member 2	0.018
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.018
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.018	Mouse
MYOD1	myogenic differentiation 1	0.018
JAK2	Janus kinase 2	0.018
HR	hairless homolog (mouse)	0.017
BHLHE40	basic helix-loop-helix family, member e40	0.017
PDE4DIP	phosphodiesterase 4D interacting protein	0.017
HOXC11	homeobox C11	0.017
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.017
FOXA2	forkhead box A2	0.017
HIC1	hypermethylated in cancer 1	0.017
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.016
ZFYVE9	zinc finger, FYVE domain containing 9	0.016
CGN	cingulin	0.016
NFIL3	nuclear factor, interleukin 3 regulated	0.016
KRT6C	keratin 6C	0.016
NCOA3	nuclear receptor coactivator 3	0.016
JUB	jub, ajuba homolog (Xenopus laevis)	0.016
ZNF775	zinc finger protein 775	0.016
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.016
SIM2	single-minded homolog 2 (Drosophila)	0.016
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.016
FOXD3	forkhead box D3	0.016
GATAD2B	GATA zinc finger domain containing 2B	0.016
VHL	von Hippel-Lindau tumor suppressor	0.016
EPPK1	epiplakin 1	0.016
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.016
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.015
PPARA	peroxisome proliferator-activated receptor alpha	0.015	Human
TGFB2	transforming growth factor, beta 2	0.015
NCOA6	nuclear receptor coactivator 6	0.015
SALL2	sal-like 2 (Drosophila)	0.015
ELF5	E74-like factor 5 (ets domain transcription factor)	0.015
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.015
TEAD4	TEA domain family member 4	0.015
SFRP1	secreted frizzled-related protein 1	0.015
CAV1	caveolin 1, caveolae protein, 22kDa	0.015	Mouse
CSNK1D	casein kinase 1, delta	0.015
HNF1A	HNF1 homeobox A	0.015
SRSF7	serine/arginine-rich splicing factor 7	0.015
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.015
JAK1	Janus kinase 1	0.014
FOSL1	FOS-like antigen 1	0.014
TNK1	tyrosine kinase, non-receptor, 1	0.014
ARHGAP1	Rho GTPase activating protein 1	0.014
BTRC	beta-transducin repeat containing	0.014
GRIP1	glutamate receptor interacting protein 1	0.014
SOX2	SRY (sex determining region Y)-box 2	0.014	Mouse
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.014
EHF	ets homologous factor	0.014
MAML1	mastermind-like 1 (Drosophila)	0.014
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.014
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.014
PDX1	pancreatic and duodenal homeobox 1	0.014
AMOTL1	angiomotin like 1	0.014
WT1	Wilms tumor 1	0.013
COLEC12	collectin sub-family member 12	0.013
HOXC8	homeobox C8	0.013	Human
FOXF1	forkhead box F1	0.013
HOXA3	homeobox A3	0.013
YY1	YY1 transcription factor	0.013
FOXF2	forkhead box F2	0.013
DDIT3	DNA-damage-inducible transcript 3	0.013
ATF3	activating transcription factor 3	0.013
MED25	mediator complex subunit 25	0.013
IL2RB	interleukin 2 receptor, beta	0.013
HOXA13	homeobox A13	0.013
AKIP1	A kinase (PRKA) interacting protein 1	0.013
C1orf106	chromosome 1 open reading frame 106	0.013
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.013
F2R	coagulation factor II (thrombin) receptor	0.013
EPS15	epidermal growth factor receptor pathway substrate 15	0.013
DLL1	delta-like 1 (Drosophila)	0.013	Mouse
PROX1	prospero homeobox 1	0.013
HOXC4	homeobox C4	0.013	Human
LIFR	leukemia inhibitory factor receptor alpha	0.013
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.013
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.013
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.013
WNT7A	wingless-type MMTV integration site family, member 7A	0.013
PAX6	paired box 6	0.013	Mouse
TP73	tumor protein p73	0.012
ZFPM1	zinc finger protein, multitype 1	0.012
HOXA4	homeobox A4	0.012	Human
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.012
SMAD6	SMAD family member 6	0.012
SMAD9	SMAD family member 9	0.012
AGTR1	angiotensin II receptor, type 1	0.012
LRP6	low density lipoprotein receptor-related protein 6	0.012
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.012
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.012
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.012
HOXB2	homeobox B2	0.012
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.012
APC	adenomatous polyposis coli	0.012	Mouse
HOXB13	homeobox B13	0.012
HOXD10	homeobox D10	0.012
GLI3	GLI family zinc finger 3	0.012	Fly
SOX13	SRY (sex determining region Y)-box 13	0.012
PHLDA2	pleckstrin homology-like domain, family A, member 2	0.012
FERMT2	fermitin family member 2	0.011
TFCP2L1	transcription factor CP2-like 1	0.011
ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	0.011
RYR2	ryanodine receptor 2 (cardiac)	0.011
ALX4	ALX homeobox 4	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011
BBS1	Bardet-Biedl syndrome 1	0.011
OVOL1	ovo-like 1(Drosophila)	0.011	Human
BMP2	bone morphogenetic protein 2	0.011	Human
HOXD9	homeobox D9	0.011
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.011
OTP	orthopedia homeobox	0.011
ACACA	acetyl-CoA carboxylase alpha	0.011
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
CTNND1	catenin (cadherin-associated protein), delta 1	0.011
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.011
H3F3B	H3 histone, family 3B (H3.3B)	0.011
TAL1	T-cell acute lymphocytic leukemia 1	0.011	Zebrafish
SHROOM3	shroom family member 3	0.011
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.011
HOXB8	homeobox B8	0.011	Human
SKIL	SKI-like oncogene	0.011
FOXC1	forkhead box C1	0.011
ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	0.011
PRL	prolactin	0.011
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.011
KAT2B	K(lysine) acetyltransferase 2B	0.011
TEAD3	TEA domain family member 3	0.011
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.011
BTG1	B-cell translocation gene 1, anti-proliferative	0.011
IRS1	insulin receptor substrate 1	0.011
SH2D3A	SH2 domain containing 3A	0.011
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011
FBXW7	F-box and WD repeat domain containing 7	0.011
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.011
CHD9	chromodomain helicase DNA binding protein 9	0.011
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.011
TWIST1	twist homolog 1 (Drosophila)	0.011
SPRED1	sprouty-related, EVH1 domain containing 1	0.010
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.010
EPHA8	EPH receptor A8	0.010
HOXD8	homeobox D8	0.010	Human
NPAS2	neuronal PAS domain protein 2	0.010
CCND2	cyclin D2	0.010
TRAP1	TNF receptor-associated protein 1	0.010
NOG	noggin	0.010
ZNF655	zinc finger protein 655	0.010
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.010
FLT4	fms-related tyrosine kinase 4	0.010
FXYD3	FXYD domain containing ion transport regulator 3	0.010