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Homo sapiens

32 genes annotated in human

regulation of intracellular steroid hormone receptor signaling pathway

Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of intracellular steroid hormone receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of intracellular steroid hormone receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
ESR1	estrogen receptor 1	1.000
CREBBP	CREB binding protein	0.997	Human
NCOA1	nuclear receptor coactivator 1	0.980
AR	androgen receptor	0.963	Mouse
HDAC1	histone deacetylase 1	0.949
EP300	E1A binding protein p300	0.939
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.723
NCOA3	nuclear receptor coactivator 3	0.714
NCOA2	nuclear receptor coactivator 2	0.698	Rat
KAT2B	K(lysine) acetyltransferase 2B	0.644
SMAD3	SMAD family member 3	0.555
RB1	retinoblastoma 1	0.554
TRIM39	tripartite motif containing 39	0.541	Human
MTA1	metastasis associated 1	0.493
QKI	quaking homolog, KH domain RNA binding (mouse)	0.472
C16orf53	chromosome 16 open reading frame 53	0.455
POU5F1	POU class 5 homeobox 1	0.412
ARID1A	AT rich interactive domain 1A (SWI-like)	0.396
RORA	RAR-related orphan receptor A	0.383
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.380	Rat
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.361
NCOA6	nuclear receptor coactivator 6	0.278
RXRA	retinoid X receptor, alpha	0.276
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.275
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.266
CNOT8	CCR4-NOT transcription complex, subunit 8	0.251
HIPK2	homeodomain interacting protein kinase 2	0.242
MED15	mediator complex subunit 15	0.240
STRN	striatin, calmodulin binding protein	0.216
SMAD9	SMAD family member 9	0.214
NCOR1	nuclear receptor corepressor 1	0.206
LDB1	LIM domain binding 1	0.206
UBA1	ubiquitin-like modifier activating enzyme 1	0.203
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.190
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.188
MTA3	metastasis associated 1 family, member 3	0.184
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.166
SP1	Sp1 transcription factor	0.164
MBD1	methyl-CpG binding domain protein 1	0.157
RNF5	ring finger protein 5	0.149
DAXX	death-domain associated protein	0.142
ESR2	estrogen receptor 2 (ER beta)	0.142
PML	promyelocytic leukemia	0.139
CLOCK	clock homolog (mouse)	0.135	Mouse
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.133
SKIL	SKI-like oncogene	0.131
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.123
RNF126	ring finger protein 126	0.112
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.111
RARA	retinoic acid receptor, alpha	0.111
FOXO1	forkhead box O1	0.106
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.093	Mouse
SMAD4	SMAD family member 4	0.089
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.088
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.087
ZNF263	zinc finger protein 263	0.080
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.077
MTA2	metastasis associated 1 family, member 2	0.074
RNF111	ring finger protein 111	0.071
TSC22D1	TSC22 domain family, member 1	0.070
NRIP1	nuclear receptor interacting protein 1	0.070
MYO6	myosin VI	0.069
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.065
ARRB1	arrestin, beta 1	0.062	Human
CNOT3	CCR4-NOT transcription complex, subunit 3	0.062
SMAD1	SMAD family member 1	0.057
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.055
YY1	YY1 transcription factor	0.054
SKP1	S-phase kinase-associated protein 1	0.054
PARP1	poly (ADP-ribose) polymerase 1	0.053
BMPR1B	bone morphogenetic protein receptor, type IB	0.052
CNOT4	CCR4-NOT transcription complex, subunit 4	0.051
GRIP1	glutamate receptor interacting protein 1	0.048
TRIM43	tripartite motif containing 43	0.048
LDB2	LIM domain binding 2	0.048
UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)	0.045
KDM1A	lysine (K)-specific demethylase 1A	0.043
LMO4	LIM domain only 4	0.043	Human
PIAS1	protein inhibitor of activated STAT, 1	0.043	Human
PPP5C	protein phosphatase 5, catalytic subunit	0.040	Rat
FAM40A	family with sequence similarity 40, member A	0.037
SP3	Sp3 transcription factor	0.037
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.037
SIRT1	sirtuin 1	0.036
HIPK1	homeodomain interacting protein kinase 1	0.035
CSNK1E	casein kinase 1, epsilon	0.034
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.034
SMAD2	SMAD family member 2	0.033
SEC24D	SEC24 family, member D (S. cerevisiae)	0.032
CNOT6	CCR4-NOT transcription complex, subunit 6	0.031
RNF4	ring finger protein 4	0.031
RNF11	ring finger protein 11	0.031
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.031
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.030
CHD3	chromodomain helicase DNA binding protein 3	0.030
TRIM5	tripartite motif containing 5	0.030	Human
CUEDC2	CUE domain containing 2	0.030
SIAH1	seven in absentia homolog 1 (Drosophila)	0.030
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.030
SOX2	SRY (sex determining region Y)-box 2	0.029
AHR	aryl hydrocarbon receptor	0.029
C14orf43	chromosome 14 open reading frame 43	0.029
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.028
TAL1	T-cell acute lymphocytic leukemia 1	0.028
XIAP	X-linked inhibitor of apoptosis	0.028
NOG	noggin	0.027
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.027
ARIH2	ariadne homolog 2 (Drosophila)	0.027
SORBS2	sorbin and SH3 domain containing 2	0.026
RBPMS	RNA binding protein with multiple splicing	0.026
ZNF473	zinc finger protein 473	0.026
TF	transferrin	0.026
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.025
SP100	SP100 nuclear antigen	0.025
RNF114	ring finger protein 114	0.025
TRIM34	tripartite motif containing 34	0.025
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.025
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.025
SH3RF3	SH3 domain containing ring finger 3	0.024
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.024
ONECUT1	one cut homeobox 1	0.024
CBX5	chromobox homolog 5	0.024
AKAP13	A kinase (PRKA) anchor protein 13	0.024
CXXC5	CXXC finger protein 5	0.024
MAP2K4	mitogen-activated protein kinase kinase 4	0.023
BFAR	bifunctional apoptosis regulator	0.023
AXIN1	axin 1	0.023
SOX1	SRY (sex determining region Y)-box 1	0.023
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.023
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.022
CNOT2	CCR4-NOT transcription complex, subunit 2	0.022
ZEB2	zinc finger E-box binding homeobox 2	0.022
GSN	gelsolin	0.022
TRIM27	tripartite motif containing 27	0.021	Human
C10orf46	chromosome 10 open reading frame 46	0.021
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.021
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.020
MAPK10	mitogen-activated protein kinase 10	0.020
STK24	serine/threonine kinase 24	0.020
MED13	mediator complex subunit 13	0.020
GATAD2A	GATA zinc finger domain containing 2A	0.020
CNOT1	CCR4-NOT transcription complex, subunit 1	0.020
TRIM52	tripartite motif containing 52	0.019
SREBF2	sterol regulatory element binding transcription factor 2	0.019
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.019
SPOP	speckle-type POZ protein	0.019
MYST2	MYST histone acetyltransferase 2	0.019
BRCA1	breast cancer 1, early onset	0.019
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.019
MARCH7	membrane-associated ring finger (C3HC4) 7	0.019
GATAD2B	GATA zinc finger domain containing 2B	0.018
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.018
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.018
TUFM	Tu translation elongation factor, mitochondrial	0.018
TRIM26	tripartite motif containing 26	0.018
DZIP3	DAZ interacting protein 3, zinc finger	0.017
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.017
HNF4A	hepatocyte nuclear factor 4, alpha	0.017
IGF1R	insulin-like growth factor 1 receptor	0.017
HNF1A	HNF1 homeobox A	0.016
MAPK14	mitogen-activated protein kinase 14	0.016
FOXD3	forkhead box D3	0.016	Human
E2F1	E2F transcription factor 1	0.016
LAPTM5	lysosomal protein transmembrane 5	0.016
ZNRF1	zinc and ring finger 1	0.016
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.016
CDK8	cyclin-dependent kinase 8	0.016
PELP1	proline, glutamate and leucine rich protein 1	0.016
CSNK1D	casein kinase 1, delta	0.016
ATXN1	ataxin 1	0.016
AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)	0.016
GSK3B	glycogen synthase kinase 3 beta	0.016
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.016
TRIM21	tripartite motif containing 21	0.016	Human
SMAD6	SMAD family member 6	0.015
SLMAP	sarcolemma associated protein	0.015
FOXA1	forkhead box A1	0.015
TRIM8	tripartite motif containing 8	0.015
TNRC6B	trinucleotide repeat containing 6B	0.015
MBD2	methyl-CpG binding domain protein 2	0.015
SOCS1	suppressor of cytokine signaling 1	0.015
BMP4	bone morphogenetic protein 4	0.015
UNC45A	unc-45 homolog A (C. elegans)	0.015
PIAS3	protein inhibitor of activated STAT, 3	0.015	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.015
MED25	mediator complex subunit 25	0.015
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.015
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.015
ARHGAP1	Rho GTPase activating protein 1	0.014
ARNT	aryl hydrocarbon receptor nuclear translocator	0.014
SETD7	SET domain containing (lysine methyltransferase) 7	0.014
WDR5	WD repeat domain 5	0.014
CNOT7	CCR4-NOT transcription complex, subunit 7	0.014
SOD1	superoxide dismutase 1, soluble	0.014
HIST2H2AB	histone cluster 2, H2ab	0.014
RYBP	RING1 and YY1 binding protein	0.014
DTX3L	deltex 3-like (Drosophila)	0.014
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.014
RBL2	retinoblastoma-like 2 (p130)	0.014
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.014	Human
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.013
PYCR2	pyrroline-5-carboxylate reductase family, member 2	0.013
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.013	Human
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.013
COL2A1	collagen, type II, alpha 1	0.013
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.013
RNF130	ring finger protein 130	0.013
CHFR	checkpoint with forkhead and ring finger domains	0.013
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.013
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.013	Mouse
RBBP5	retinoblastoma binding protein 5	0.013
LRRK2	leucine-rich repeat kinase 2	0.013
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.013
MED13L	mediator complex subunit 13-like	0.013
TRIM17	tripartite motif containing 17	0.013	Human
ARRB2	arrestin, beta 2	0.013
RCOR1	REST corepressor 1	0.013
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.012
PLCD3	phospholipase C, delta 3	0.012
NUP153	nucleoporin 153kDa	0.012
TRIM35	tripartite motif containing 35	0.012
CDK17	cyclin-dependent kinase 17	0.012
WNT11	wingless-type MMTV integration site family, member 11	0.012
TRIM41	tripartite motif containing 41	0.012	Human
FNDC3A	fibronectin type III domain containing 3A	0.012
ESRRG	estrogen-related receptor gamma	0.012
PDIA3	protein disulfide isomerase family A, member 3	0.012
FYN	FYN oncogene related to SRC, FGR, YES	0.012
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.012
PITX2	paired-like homeodomain 2	0.012
HDAC2	histone deacetylase 2	0.012	Human
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.012
NCCRP1	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	0.012
FAM110A	family with sequence similarity 110, member A	0.012
IRF9	interferon regulatory factor 9	0.012
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.012
VEZF1	vascular endothelial zinc finger 1	0.012
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.012
FOXF2	forkhead box F2	0.012
EVC2	Ellis van Creveld syndrome 2	0.012
MTRNR2L1	MT-RNR2-like 1	0.012
RHOU	ras homolog gene family, member U	0.012
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.012
STAT5A	signal transducer and activator of transcription 5A	0.012
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.012
TRIM4	tripartite motif containing 4	0.012	Human
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.011
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.011
LHX1	LIM homeobox 1	0.011
BRAP	BRCA1 associated protein	0.011
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.011
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.011
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.011
MYOD1	myogenic differentiation 1	0.011
CTSO	cathepsin O	0.011
ACAN	aggrecan	0.011
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.011
IQGAP1	IQ motif containing GTPase activating protein 1	0.011
SH3KBP1	SH3-domain kinase binding protein 1	0.011
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.011
PDIA4	protein disulfide isomerase family A, member 4	0.011
RNF6	ring finger protein (C3H2C3 type) 6	0.011
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.011
HOXC8	homeobox C8	0.011
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.011
RALYL	RALY RNA binding protein-like	0.011
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.011
PRDX2	peroxiredoxin 2	0.011
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.011
IFI16	interferon, gamma-inducible protein 16	0.011
ELK1	ELK1, member of ETS oncogene family	0.011
MKRN3	makorin ring finger protein 3	0.011
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.011
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.011
ITSN1	intersectin 1 (SH3 domain protein)	0.011
FZD8	frizzled homolog 8 (Drosophila)	0.011
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.011
RNF38	ring finger protein 38	0.011	Human
GNMT	glycine N-methyltransferase	0.011
FGF8	fibroblast growth factor 8 (androgen-induced)	0.010
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.010
OXA1L	oxidase (cytochrome c) assembly 1-like	0.010
TCF21	transcription factor 21	0.010	Mouse
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.010
SMAD7	SMAD family member 7	0.010
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.010
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.010
INHBB	inhibin, beta B	0.010