IMP

Process View

Homo sapiens

39 genes annotated in human

cholesterol transport

The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cholesterol transport" (in gray)

Name	Description	Probability	Func Analog Organism
APOA1	apolipoprotein A-I	1.000
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
C1QA	complement component 1, q subcomponent, A chain	0.997	Human
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.964
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.947
APOE	apolipoprotein E	0.904
ALB	albumin	0.896
HP	haptoglobin	0.887
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.859
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.831
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.816
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.813
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.803	Human
TNIP2	TNFAIP3 interacting protein 2	0.791
APOC1	apolipoprotein C-I	0.704
LDLR	low density lipoprotein receptor	0.641
CREBBP	CREB binding protein	0.632
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.607
C1QC	complement component 1, q subcomponent, C chain	0.599	Human
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.522
A2M	alpha-2-macroglobulin	0.507
ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	0.498
APOA2	apolipoprotein A-II	0.431
MED15	mediator complex subunit 15	0.426
BCL3	B-cell CLL/lymphoma 3	0.422	Human
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.378
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.370
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.370
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.294
PELI3	pellino homolog 3 (Drosophila)	0.281
CAV2	caveolin 2	0.270
APOC3	apolipoprotein C-III	0.270
DHCR7	7-dehydrocholesterol reductase	0.264
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.258
STX12	syntaxin 12	0.257
C1QB	complement component 1, q subcomponent, B chain	0.253	Human
CHUK	conserved helix-loop-helix ubiquitous kinase	0.243
INSIG1	insulin induced gene 1	0.236
APOC2	apolipoprotein C-II	0.236
APP	amyloid beta (A4) precursor protein	0.220
LCAT	lecithin-cholesterol acyltransferase	0.201
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.169
IRAK2	interleukin-1 receptor-associated kinase 2	0.142
PTEN	phosphatase and tensin homolog	0.128
EPS8	epidermal growth factor receptor pathway substrate 8	0.124
SMO	smoothened homolog (Drosophila)	0.095
EP300	E1A binding protein p300	0.089
LAMP2	lysosomal-associated membrane protein 2	0.084
SQLE	squalene epoxidase	0.082
APOB	apolipoprotein B (including Ag(x) antigen)	0.082
NCOA1	nuclear receptor coactivator 1	0.080
HNF4A	hepatocyte nuclear factor 4, alpha	0.079
ANXA4	annexin A4	0.074
FGA	fibrinogen alpha chain	0.073
MAPT	microtubule-associated protein tau	0.070
PRKCZ	protein kinase C, zeta	0.070
KAT2B	K(lysine) acetyltransferase 2B	0.069
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.062	Human
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.061
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.058
ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	0.055
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.055
PDZK1	PDZ domain containing 1	0.055
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.054
PTPRF	protein tyrosine phosphatase, receptor type, F	0.053
RRAGC	Ras-related GTP binding C	0.053
TNIP1	TNFAIP3 interacting protein 1	0.050
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.049
VAMP4	vesicle-associated membrane protein 4	0.049
C7orf59	chromosome 7 open reading frame 59	0.047
NSF	N-ethylmaleimide-sensitive factor	0.046
LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.045
RPL18A	ribosomal protein L18a	0.044
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.044
RXRA	retinoid X receptor, alpha	0.043
STON2	stonin 2	0.041
MBL2	mannose-binding lectin (protein C) 2, soluble	0.040
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.039
FOXO3	forkhead box O3	0.039
GPNMB	glycoprotein (transmembrane) nmb	0.039
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.038
FOXO1	forkhead box O1	0.038
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.038
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.036
TTR	transthyretin	0.036
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.036
AGFG1	ArfGAP with FG repeats 1	0.035
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.035
AHSG	alpha-2-HS-glycoprotein	0.035
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.034
MED25	mediator complex subunit 25	0.034
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.034
PLTP	phospholipid transfer protein	0.033
PCSK9	proprotein convertase subtilisin/kexin type 9	0.032
ANXA1	annexin A1	0.032
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.032
QKI	quaking homolog, KH domain RNA binding (mouse)	0.031
ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	0.031
SC4MOL	sterol-C4-methyl oxidase-like	0.031
SNX3	sorting nexin 3	0.030
MDK	midkine (neurite growth-promoting factor 2)	0.030
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.030
FABP4	fatty acid binding protein 4, adipocyte	0.030
MARCO	macrophage receptor with collagenous structure	0.029
LRP1	low density lipoprotein receptor-related protein 1	0.029	Mouse
TREM2	triggering receptor expressed on myeloid cells 2	0.028
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.028
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.028
PRKCDBP	protein kinase C, delta binding protein	0.027
SREBF1	sterol regulatory element binding transcription factor 1	0.027	Human
MSTO1	misato homolog 1 (Drosophila)	0.027
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.027
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.027
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.026
CARD11	caspase recruitment domain family, member 11	0.025
LRRK2	leucine-rich repeat kinase 2	0.025
UBL3	ubiquitin-like 3	0.024
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.024
RARA	retinoic acid receptor, alpha	0.024
FASN	fatty acid synthase	0.024
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.024
SMAD3	SMAD family member 3	0.023
TRAF6	TNF receptor-associated factor 6	0.023
SGMS1	sphingomyelin synthase 1	0.023
EPS15	epidermal growth factor receptor pathway substrate 15	0.023
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.023
CREBL2	cAMP responsive element binding protein-like 2	0.023
PRCP	prolylcarboxypeptidase (angiotensinase C)	0.022
HPD	4-hydroxyphenylpyruvate dioxygenase	0.022
IRAK4	interleukin-1 receptor-associated kinase 4	0.022
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.022
CD68	CD68 molecule	0.022
WNT3A	wingless-type MMTV integration site family, member 3A	0.022
CD163	CD163 molecule	0.021
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.021
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.020
CAV1	caveolin 1, caveolae protein, 22kDa	0.020	Zebrafish
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.020
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.020
ACP5	acid phosphatase 5, tartrate resistant	0.020
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.019
BRI3	brain protein I3	0.019
MS4A7	membrane-spanning 4-domains, subfamily A, member 7	0.019
OSTM1	osteopetrosis associated transmembrane protein 1	0.019
TRAF5	TNF receptor-associated factor 5	0.019
KIAA1377	KIAA1377	0.019
CAT	catalase	0.018
SBNO2	strawberry notch homolog 2 (Drosophila)	0.018
FAM83C	family with sequence similarity 83, member C	0.018
THPO	thrombopoietin	0.018
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.018
SPTLC1	serine palmitoyltransferase, long chain base subunit 1	0.018
PROX1	prospero homeobox 1	0.018
FLOT1	flotillin 1	0.018
EDF1	endothelial differentiation-related factor 1	0.017
IDI1	isopentenyl-diphosphate delta isomerase 1	0.017
CRP	C-reactive protein, pentraxin-related	0.017
F2R	coagulation factor II (thrombin) receptor	0.017
FTL	ferritin, light polypeptide	0.017
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.017
RBP4	retinol binding protein 4, plasma	0.017
C4B	complement component 4B (Chido blood group)	0.017
TMEM59	transmembrane protein 59	0.017
TMEM176A	transmembrane protein 176A	0.017
FCHO2	FCH domain only 2	0.017
ITM2B	integral membrane protein 2B	0.017
CA5A	carbonic anhydrase VA, mitochondrial	0.017
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.016
LBP	lipopolysaccharide binding protein	0.016
MRC1	mannose receptor, C type 1	0.016
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.016
GOLGB1	golgin B1	0.016
PDCD6IP	programmed cell death 6 interacting protein	0.016
SCARB1	scavenger receptor class B, member 1	0.016
SLC35A1	solute carrier family 35 (CMP-sialic acid transporter), member A1	0.016
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.016
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.015
DCN	decorin	0.015
AMBP	alpha-1-microglobulin/bikunin precursor	0.015
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.015
RRAS	related RAS viral (r-ras) oncogene homolog	0.015
TXNRD1	thioredoxin reductase 1	0.015
LIPC	lipase, hepatic	0.015	Human Mouse
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.015
PHKB	phosphorylase kinase, beta	0.015
PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	0.015
HNF1B	HNF1 homeobox B	0.015
SREBF2	sterol regulatory element binding transcription factor 2	0.015
MVK	mevalonate kinase	0.015
KLHL2	kelch-like 2, Mayven (Drosophila)	0.015
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.015
MTMR6	myotubularin related protein 6	0.015
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	0.015
MAST1	microtubule associated serine/threonine kinase 1	0.015
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.015
C2	complement component 2	0.015
BMP2K	BMP2 inducible kinase	0.015
HPX	hemopexin	0.014
PROCR	protein C receptor, endothelial	0.014
ABHD3	abhydrolase domain containing 3	0.014
MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.014
STARD4	StAR-related lipid transfer (START) domain containing 4	0.014
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.014
PELI1	pellino homolog 1 (Drosophila)	0.014
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.014
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.014
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.014
SDPR	serum deprivation response	0.014
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.014
TMSB10	thymosin beta 10	0.014
LOXL4	lysyl oxidase-like 4	0.014
SERINC1	serine incorporator 1	0.014
TLR7	toll-like receptor 7	0.014
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.014
F11	coagulation factor XI	0.014
MYLIP	myosin regulatory light chain interacting protein	0.014
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	0.013
ASCC2	activating signal cointegrator 1 complex subunit 2	0.013
WRN	Werner syndrome, RecQ helicase-like	0.013
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.013
CFB	complement factor B	0.013
TIMP2	TIMP metallopeptidase inhibitor 2	0.013
VIM	vimentin	0.013
AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.013
EXOC1	exocyst complex component 1	0.013
HEXB	hexosaminidase B (beta polypeptide)	0.013
PPARG	peroxisome proliferator-activated receptor gamma	0.013
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.013
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.013
CTSL1	cathepsin L1	0.013
RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	0.013
C1S	complement component 1, s subcomponent	0.013
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.013
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.013
TBC1D10A	TBC1 domain family, member 10A	0.013
STXBP3	syntaxin binding protein 3	0.013
C3	complement component 3	0.012
CHMP2B	chromatin modifying protein 2B	0.012
CTSH	cathepsin H	0.012
CSTB	cystatin B (stefin B)	0.012
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.012
EDNRB	endothelin receptor type B	0.012
SDS	serine dehydratase	0.012
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.012
CALCR	calcitonin receptor	0.012
NUPR1	nuclear protein, transcriptional regulator, 1	0.012
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.012
BHMT	betaine--homocysteine S-methyltransferase	0.012
FCGRT	Fc fragment of IgG, receptor, transporter, alpha	0.012
PID1	phosphotyrosine interaction domain containing 1	0.012
MTTP	microsomal triglyceride transfer protein	0.012
RIBC2	RIB43A domain with coiled-coils 2	0.012
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.012
AVPR2	arginine vasopressin receptor 2	0.012
MYD88	myeloid differentiation primary response gene (88)	0.012
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.011
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.011
VSIG4	V-set and immunoglobulin domain containing 4	0.011
CTSD	cathepsin D	0.011
CFD	complement factor D (adipsin)	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
C1R	complement component 1, r subcomponent	0.011
CST3	cystatin C	0.011
BCL10	B-cell CLL/lymphoma 10	0.011
FABP1	fatty acid binding protein 1, liver	0.011
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.011
CD164	CD164 molecule, sialomucin	0.011
NCOA6	nuclear receptor coactivator 6	0.011
SOCS6	suppressor of cytokine signaling 6	0.011
BCKDHB	branched chain keto acid dehydrogenase E1, beta polypeptide	0.011
RBP2	retinol binding protein 2, cellular	0.011
PELI2	pellino homolog 2 (Drosophila)	0.011
RP2	retinitis pigmentosa 2 (X-linked recessive)	0.011
F2	coagulation factor II (thrombin)	0.011
VTN	vitronectin	0.011
ACSL1	acyl-CoA synthetase long-chain family member 1	0.011
TMEM173	transmembrane protein 173	0.011
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.011
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.011
TCN2	transcobalamin II	0.011
SORBS2	sorbin and SH3 domain containing 2	0.011
TLR4	toll-like receptor 4	0.011
GAA	glucosidase, alpha; acid	0.011
AFP	alpha-fetoprotein	0.011
BTRC	beta-transducin repeat containing	0.011
CP	ceruloplasmin (ferroxidase)	0.011
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.011
PPARA	peroxisome proliferator-activated receptor alpha	0.010
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	0.010
TUBB6	tubulin, beta 6	0.010
HABP2	hyaluronan binding protein 2	0.010
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.010
ADD3	adducin 3 (gamma)	0.010
LMBRD1	LMBR1 domain containing 1	0.010
CTNND1	catenin (cadherin-associated protein), delta 1	0.010
MYO7A	myosin VIIA	0.010
YPEL5	yippee-like 5 (Drosophila)	0.010
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.010
RDH5	retinol dehydrogenase 5 (11-cis/9-cis)	0.010
SNX6	sorting nexin 6	0.010
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.010
PC	pyruvate carboxylase	0.010
GPX3	glutathione peroxidase 3 (plasma)	0.010
C8G	complement component 8, gamma polypeptide	0.010
ALPI	alkaline phosphatase, intestinal	0.010
THRSP	thyroid hormone responsive	0.010
ACACA	acetyl-CoA carboxylase alpha	0.010