IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

regulation of tolerance induction

GO:0002643

Any process that modulates the frequency, rate, or extent of tolerance induction.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of tolerance induction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of tolerance induction" (in gray)

Name	Description	Probability	Func Analog Organism
B2M	beta-2-microglobulin	0.915
HLA-C	major histocompatibility complex, class I, C	0.909	Human
HLA-A	major histocompatibility complex, class I, A	0.804	Human
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.710
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.707	Human
HLA-G	major histocompatibility complex, class I, G	0.617
HLA-B	major histocompatibility complex, class I, B	0.576
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.555
HLA-F	major histocompatibility complex, class I, F	0.467	Human
HLA-E	major histocompatibility complex, class I, E	0.349	Human
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.322
PILRA	paired immunoglobin-like type 2 receptor alpha	0.238
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.222
TGFB3	transforming growth factor, beta 3	0.192
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.142
IRAK2	interleukin-1 receptor-associated kinase 2	0.120
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.104
TGIF1	TGFB-induced factor homeobox 1	0.084
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.081
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.078	Human
CALCOCO2	calcium binding and coiled-coil domain 2	0.074
CD247	CD247 molecule	0.072
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.066
TAPBP	TAP binding protein (tapasin)	0.065
TYMP	thymidine phosphorylase	0.064
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.061
ENG	endoglin	0.058
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.055
LCK	lymphocyte-specific protein tyrosine kinase	0.048
SIGLEC7	sialic acid binding Ig-like lectin 7	0.045
CD33	CD33 molecule	0.045
BTN3A1	butyrophilin, subfamily 3, member A1	0.042
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.037
PTAFR	platelet-activating factor receptor	0.028
HK3	hexokinase 3 (white cell)	0.028
TPP1	tripeptidyl peptidase I	0.026
TREM1	triggering receptor expressed on myeloid cells 1	0.026
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.026
AOAH	acyloxyacyl hydrolase (neutrophil)	0.025
CSK	c-src tyrosine kinase	0.024
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.024
CA12	carbonic anhydrase XII	0.024
CD2AP	CD2-associated protein	0.023
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.023	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.022
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.021
USP38	ubiquitin specific peptidase 38	0.021
CCR1	chemokine (C-C motif) receptor 1	0.020
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.020
RNF11	ring finger protein 11	0.020
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.020
CD14	CD14 molecule	0.020
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.018
HDAC9	histone deacetylase 9	0.018
CRY1	cryptochrome 1 (photolyase-like)	0.018
DNM2	dynamin 2	0.018
SIRPB1	signal-regulatory protein beta 1	0.018
CD300C	CD300c molecule	0.018
DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2	0.018
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.018
NLRP3	NLR family, pyrin domain containing 3	0.017
TGFB1	transforming growth factor, beta 1	0.017
TLR8	toll-like receptor 8	0.017
TAPBPL	TAP binding protein-like	0.017
NOD2	nucleotide-binding oligomerization domain containing 2	0.016
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.016
NCK2	NCK adaptor protein 2	0.016
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.016
HCP5	HLA complex P5	0.015
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.015
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.015
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.015
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.015
CST3	cystatin C	0.015
PGCP	plasma glutamate carboxypeptidase	0.015
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.014
FCAR	Fc fragment of IgA, receptor for	0.014	Human
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.014
IL10RA	interleukin 10 receptor, alpha	0.014
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.014
ASGR2	asialoglycoprotein receptor 2	0.014
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.013	Human
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.013
DTX1	deltex homolog 1 (Drosophila)	0.013
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.013
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.013
IL2RG	interleukin 2 receptor, gamma	0.013
TRAF6	TNF receptor-associated factor 6	0.013
HDAC7	histone deacetylase 7	0.013
BLNK	B-cell linker	0.013
CD163	CD163 molecule	0.013
PSAP	prosaposin	0.013
FPR2	formyl peptide receptor 2	0.013
IL10RB	interleukin 10 receptor, beta	0.013
CTBP1	C-terminal binding protein 1	0.013
RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	0.012
NRP1	neuropilin 1	0.012
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.012
TGFBR1	transforming growth factor, beta receptor 1	0.012
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.012
CCR3	chemokine (C-C motif) receptor 3	0.012
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.012
USP15	ubiquitin specific peptidase 15	0.012
FSTL1	follistatin-like 1	0.012
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.012
C1orf38	chromosome 1 open reading frame 38	0.011
MEX3C	mex-3 homolog C (C. elegans)	0.011
SNX9	sorting nexin 9	0.011
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.011	Human
CMKLR1	chemokine-like receptor 1	0.011
TP53RK	TP53 regulating kinase	0.011
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.011
BTN3A2	butyrophilin, subfamily 3, member A2	0.011
MYO6	myosin VI	0.011
MAP2K5	mitogen-activated protein kinase kinase 5	0.011
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.011
PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	0.011
BIN2	bridging integrator 2	0.011
BPI	bactericidal/permeability-increasing protein	0.011
CFP	complement factor properdin	0.011
CCR7	chemokine (C-C motif) receptor 7	0.011
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.011
IL32	interleukin 32	0.011
BEST1	bestrophin 1	0.010
CTBP2	C-terminal binding protein 2	0.010
CCR2	chemokine (C-C motif) receptor 2	0.010
LIMS1	LIM and senescent cell antigen-like domains 1	0.010
CD86	CD86 molecule	0.010	Rat
CD101	CD101 molecule	0.010
IKZF4	IKAROS family zinc finger 4 (Eos)	0.010
GRN	granulin	0.010
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.010
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.010	Human
MARCO	macrophage receptor with collagenous structure	0.010
SECTM1	secreted and transmembrane 1	0.010
CD300A	CD300a molecule	0.010
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.010
PECAM1	platelet/endothelial cell adhesion molecule	0.010
PRKD2	protein kinase D2	0.010
VSIG4	V-set and immunoglobulin domain containing 4	0.010
RNF168	ring finger protein 168	0.010
TCN2	transcobalamin II	0.010
EPOR	erythropoietin receptor	0.010