IMP

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Homo sapiens

26 genes annotated in human

fibroblast growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "fibroblast growth factor receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "fibroblast growth factor receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000
FGF1	fibroblast growth factor 1 (acidic)	0.999
FGFR1	fibroblast growth factor receptor 1	0.997
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.996
STAMBP	STAM binding protein	0.859
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.851
PLCG1	phospholipase C, gamma 1	0.700
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.571
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.549
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.539
FGF10	fibroblast growth factor 10	0.509
SH2D1A	SH2 domain containing 1A	0.485
SH3KBP1	SH3-domain kinase binding protein 1	0.436
FGF2	fibroblast growth factor 2 (basic)	0.432
ZUFSP	zinc finger with UFM1-specific peptidase domain	0.427
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.391
GRB2	growth factor receptor-bound protein 2	0.367	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.290
FRS2	fibroblast growth factor receptor substrate 2	0.285
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.272
HDAC7	histone deacetylase 7	0.243
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.239
TESK1	testis-specific kinase 1	0.155
CTGF	connective tissue growth factor	0.149	Mouse
SPRY2	sprouty homolog 2 (Drosophila)	0.142	Mouse Fly
TGFB1	transforming growth factor, beta 1	0.141
FGF8	fibroblast growth factor 8 (androgen-induced)	0.136
GLIS2	GLIS family zinc finger 2	0.135
CYR61	cysteine-rich, angiogenic inducer, 61	0.135
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.120
HIC1	hypermethylated in cancer 1	0.120
EGFR	epidermal growth factor receptor	0.119
COL5A1	collagen, type V, alpha 1	0.118
FN1	fibronectin 1	0.114
EEA1	early endosome antigen 1	0.105
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.097
FGF7	fibroblast growth factor 7	0.095
STMN2	stathmin-like 2	0.093
LIN28B	lin-28 homolog B (C. elegans)	0.081
ITSN1	intersectin 1 (SH3 domain protein)	0.080
APC	adenomatous polyposis coli	0.080
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.079
JAK1	Janus kinase 1	0.073
FERMT2	fermitin family member 2	0.068
ATF2	activating transcription factor 2	0.066
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.064
COL1A1	collagen, type I, alpha 1	0.064
TSG101	tumor susceptibility gene 101	0.064
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.062
KLB	klotho beta	0.060
ERBB2IP	erbb2 interacting protein	0.055
ABI1	abl-interactor 1	0.055
FYN	FYN oncogene related to SRC, FGR, YES	0.051
FGFR3	fibroblast growth factor receptor 3	0.050
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.049
NCK1	NCK adaptor protein 1	0.049
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.047	Fly
GAB2	GRB2-associated binding protein 2	0.047
PDGFC	platelet derived growth factor C	0.046
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.042
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.041
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.041
LAT	linker for activation of T cells	0.041
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.039	Fly
SLAMF1	signaling lymphocytic activation molecule family member 1	0.039
THBS1	thrombospondin 1	0.038
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.038
BMP7	bone morphogenetic protein 7	0.035
FBLN1	fibulin 1	0.035
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.034
VCAN	versican	0.034
PDGFA	platelet-derived growth factor alpha polypeptide	0.034
SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	0.034	Mouse Fly
NRP1	neuropilin 1	0.034
HSPG2	heparan sulfate proteoglycan 2	0.033
EGR1	early growth response 1	0.033
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.033
TIMP3	TIMP metallopeptidase inhibitor 3	0.032
ACTN4	actinin, alpha 4	0.031
GAB1	GRB2-associated binding protein 1	0.030
COL2A1	collagen, type II, alpha 1	0.030
COL4A1	collagen, type IV, alpha 1	0.030
PECAM1	platelet/endothelial cell adhesion molecule	0.030
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.029
COL6A1	collagen, type VI, alpha 1	0.029
TIMP2	TIMP metallopeptidase inhibitor 2	0.029
TGFB3	transforming growth factor, beta 3	0.028
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.027
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.027
CD33	CD33 molecule	0.026
EPS15	epidermal growth factor receptor pathway substrate 15	0.026
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.026
OCRL	oculocerebrorenal syndrome of Lowe	0.026
SALL2	sal-like 2 (Drosophila)	0.025
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.025
RCC1	regulator of chromosome condensation 1	0.025
FZD1	frizzled homolog 1 (Drosophila)	0.024
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.024
NGF	nerve growth factor (beta polypeptide)	0.024
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.024
SDC2	syndecan 2	0.024
BMP2	bone morphogenetic protein 2	0.024
PCOLCE	procollagen C-endopeptidase enhancer	0.024
PSEN1	presenilin 1	0.023
RET	ret proto-oncogene	0.023
JAK2	Janus kinase 2	0.023
MDFI	MyoD family inhibitor	0.023
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.022
CD2AP	CD2-associated protein	0.021
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.021
FGF19	fibroblast growth factor 19	0.021
CTSB	cathepsin B	0.020
EGR3	early growth response 3	0.020
HAS2	hyaluronan synthase 2	0.019
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.019
COL1A2	collagen, type I, alpha 2	0.019
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.019
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.019
FSTL1	follistatin-like 1	0.018
TNIK	TRAF2 and NCK interacting kinase	0.018
FGFR4	fibroblast growth factor receptor 4	0.018
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.018
GORASP1	golgi reassembly stacking protein 1, 65kDa	0.017
EPOR	erythropoietin receptor	0.017
BTRC	beta-transducin repeat containing	0.017
EGR2	early growth response 2	0.017
IL4R	interleukin 4 receptor	0.017
ERRFI1	ERBB receptor feedback inhibitor 1	0.016
ENG	endoglin	0.016
BGN	biglycan	0.016
FBXL5	F-box and leucine-rich repeat protein 5	0.016
IGFBP5	insulin-like growth factor binding protein 5	0.016
EPS8	epidermal growth factor receptor pathway substrate 8	0.016
SMC6	structural maintenance of chromosomes 6	0.016
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.016
ANGPTL2	angiopoietin-like 2	0.016
PRDM8	PR domain containing 8	0.016
TNPO1	transportin 1	0.015
PDLIM7	PDZ and LIM domain 7 (enigma)	0.015
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.015
F3	coagulation factor III (thromboplastin, tissue factor)	0.015
ETV5	ets variant 5	0.015
COIL	coilin	0.015
THBS2	thrombospondin 2	0.015	Human
PKP4	plakophilin 4	0.015
FGF4	fibroblast growth factor 4	0.015
IGF2R	insulin-like growth factor 2 receptor	0.015
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.015
LOXL2	lysyl oxidase-like 2	0.015
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.014
QKI	quaking homolog, KH domain RNA binding (mouse)	0.014
NOTCH3	notch 3	0.014
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.014
EXOC7	exocyst complex component 7	0.014
MXRA5	matrix-remodelling associated 5	0.014
FGF3	fibroblast growth factor 3	0.014
TRIP12	thyroid hormone receptor interactor 12	0.014
MT2A	metallothionein 2A	0.014
NOSTRIN	nitric oxide synthase trafficker	0.014
SOS2	son of sevenless homolog 2 (Drosophila)	0.013
SMAD3	SMAD family member 3	0.013
SH3PXD2A	SH3 and PX domains 2A	0.013
SFN	stratifin	0.013
PICALM	phosphatidylinositol binding clathrin assembly protein	0.013
IGFBP3	insulin-like growth factor binding protein 3	0.013
INHBA	inhibin, beta A	0.013
MPZL1	myelin protein zero-like 1	0.013
ZFYVE9	zinc finger, FYVE domain containing 9	0.013
FBLN2	fibulin 2	0.013
VEGFA	vascular endothelial growth factor A	0.013
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
SLC9A6	solute carrier family 9 (sodium/hydrogen exchanger), member 6	0.012
SLK	STE20-like kinase	0.012
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.012
SCARB2	scavenger receptor class B, member 2	0.012
SIRPA	signal-regulatory protein alpha	0.012
A2M	alpha-2-macroglobulin	0.012
NTM	neurotrimin	0.012
ITGB3BP	integrin beta 3 binding protein (beta3-endonexin)	0.012
THY1	Thy-1 cell surface antigen	0.012
TGFB2	transforming growth factor, beta 2	0.012
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.012
DCN	decorin	0.011
SFRP4	secreted frizzled-related protein 4	0.011
RIN2	Ras and Rab interactor 2	0.011
KRT8	keratin 8	0.011
TNC	tenascin C	0.011
COL16A1	collagen, type XVI, alpha 1	0.011
C9orf25	chromosome 9 open reading frame 25	0.011
CDH7	cadherin 7, type 2	0.011
XPOT	exportin, tRNA (nuclear export receptor for tRNAs)	0.011
SFRP2	secreted frizzled-related protein 2	0.011
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.011
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.011
COL3A1	collagen, type III, alpha 1	0.011
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.011
PJA2	praja ring finger 2	0.011
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.011
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.011
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.011
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.011
SH3BP4	SH3-domain binding protein 4	0.011
SPRED1	sprouty-related, EVH1 domain containing 1	0.010
VEGFC	vascular endothelial growth factor C	0.010
PLXDC1	plexin domain containing 1	0.010
MTPN	myotrophin	0.010
GSK3B	glycogen synthase kinase 3 beta	0.010
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.010
MAP2K1	mitogen-activated protein kinase kinase 1	0.010
WNT1	wingless-type MMTV integration site family, member 1	0.010
SOCS3	suppressor of cytokine signaling 3	0.010
COMP	cartilage oligomeric matrix protein	0.010	Human
SGMS1	sphingomyelin synthase 1	0.010
SLIT2	slit homolog 2 (Drosophila)	0.010
EMP1	epithelial membrane protein 1	0.010
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.010