IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of arp2 3 complex mediated actin nucleation

Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of arp2 3 complex mediated actin nucleation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of arp2 3 complex mediated actin nucleation" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.966
Arpc4	actin related protein 2/3 complex, subunit 4	0.885
Wdr1	WD repeat domain 1	0.690
Capzb	capping protein (actin filament) muscle Z-line, beta	0.607
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.585
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.444
Cttn	cortactin	0.429
Pfn2	profilin 2	0.420
Dbnl	drebrin-like	0.407
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.406
Fermt3	fermitin family homolog 3 (Drosophila)	0.318
Rac1	RAS-related C3 botulinum substrate 1	0.311
Arhgap9	Rho GTPase activating protein 9	0.297
Cfl1	cofilin 1, non-muscle	0.253
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.210
Arhgap1	Rho GTPase activating protein 1	0.199
Rhog	ras homolog gene family, member G	0.179
Akt1	thymoma viral proto-oncogene 1	0.172
Gabarap	gamma-aminobutyric acid receptor associated protein	0.149
Rab4b	RAB4B, member RAS oncogene family	0.129
Nckap1	NCK-associated protein 1	0.123	Human
Cdc42se1	CDC42 small effector 1	0.123
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.119
Hmha1	histocompatibility (minor) HA-1	0.112
Sept9	septin 9	0.111
Vasp	vasodilator-stimulated phosphoprotein	0.109
Cyba	cytochrome b-245, alpha polypeptide	0.107
Cotl1	coactosin-like 1 (Dictyostelium)	0.097
F11r	F11 receptor	0.094
Wipf1	WAS/WASL interacting protein family, member 1	0.087
Rnh1	ribonuclease/angiogenin inhibitor 1	0.080
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.079
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.078
Necap2	NECAP endocytosis associated 2	0.076
Hcls1	hematopoietic cell specific Lyn substrate 1	0.075
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.074
Adrbk1	adrenergic receptor kinase, beta 1	0.073
Cd37	CD37 antigen	0.069
Pfn1	profilin 1	0.068
Clic1	chloride intracellular channel 1	0.067
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.066
Actg1	actin, gamma, cytoplasmic 1	0.066
Selplg	selectin, platelet (p-selectin) ligand	0.063
Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.050
Shisa5	shisa homolog 5 (Xenopus laevis)	0.048
Actb	actin, beta	0.047
Jam3	junction adhesion molecule 3	0.047
Csk	c-src tyrosine kinase	0.044
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.044
Shkbp1	Sh3kbp1 binding protein 1	0.043
Capns1	calpain, small subunit 1	0.043
Arpc3	actin related protein 2/3 complex, subunit 3	0.043
Ilk	integrin linked kinase	0.043
Cltc	clathrin, heavy polypeptide (Hc)	0.042
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.040	Human
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.039
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.039
Pcdh10	protocadherin 10	0.039
Tjp1	tight junction protein 1	0.038
Tubb5	tubulin, beta 5	0.037
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.037
Arrb2	arrestin, beta 2	0.036
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.036
Coro1a	coronin, actin binding protein 1A	0.035	Yeast
Arpc2	actin related protein 2/3 complex, subunit 2	0.034
Txndc5	thioredoxin domain containing 5	0.034
Ltb	lymphotoxin B	0.033
Capg	capping protein (actin filament), gelsolin-like	0.033
Cdk8	cyclin-dependent kinase 8	0.033
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.032
Tmsb4x	thymosin, beta 4, X chromosome	0.032
Ifi30	interferon gamma inducible protein 30	0.031
Sipa1	signal-induced proliferation associated gene 1	0.031
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.031
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.031
Sash3	SAM and SH3 domain containing 3	0.030
Grk6	G protein-coupled receptor kinase 6	0.029
Arhgap21	Rho GTPase activating protein 21	0.029
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.029
Mapk3	mitogen-activated protein kinase 3	0.029
Gipc1	GIPC PDZ domain containing family, member 1	0.029
H2-DMa	histocompatibility 2, class II, locus DMa	0.028
Pld3	phospholipase D family, member 3	0.028
Csrp1	cysteine and glycine-rich protein 1	0.027
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.027
Gmip	Gem-interacting protein	0.027
Actn4	actinin alpha 4	0.027
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.026
Man2b1	mannosidase 2, alpha B1	0.026
Stxbp2	syntaxin binding protein 2	0.025
Lsp1	lymphocyte specific 1	0.025
Stk10	serine/threonine kinase 10	0.025
Fxyd5	FXYD domain-containing ion transport regulator 5	0.024
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.024
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.023
Ap2m1	adaptor protein complex AP-2, mu1	0.023
Pkp4	plakophilin 4	0.023
Psap	prosaposin	0.023
Lxn	latexin	0.023
Atp13a2	ATPase type 13A2	0.023
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.022
Npas3	neuronal PAS domain protein 3	0.022
Pold4	polymerase (DNA-directed), delta 4	0.022
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.022
Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.022
Rac2	RAS-related C3 botulinum substrate 2	0.022
2410001C21Rik	RIKEN cDNA 2410001C21 gene	0.022
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.021
Gorasp2	golgi reassembly stacking protein 2	0.021
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.021
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.020
Aamp	angio-associated migratory protein	0.020
Ctnna1	catenin (cadherin associated protein), alpha 1	0.020
Itm2c	integral membrane protein 2C	0.020
Ergic3	ERGIC and golgi 3	0.019
Prkcb	protein kinase C, beta	0.019
Dctn5	dynactin 5	0.019
Spna2	spectrin alpha 2	0.019
Ctsz	cathepsin Z	0.019
Pls3	plastin 3 (T-isoform)	0.019
Fkbp1a	FK506 binding protein 1a	0.019
Sri	sorcin	0.018
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.018
Pld4	phospholipase D family, member 4	0.018
Myo1g	myosin IG	0.018
Calm1	calmodulin 1	0.018
Copa	coatomer protein complex subunit alpha	0.018
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.018
Anapc4	anaphase promoting complex subunit 4	0.018
Capn1	calpain 1	0.018
Hck	hemopoietic cell kinase	0.018
Ly86	lymphocyte antigen 86	0.018
Add1	adducin 1 (alpha)	0.018
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.017
Mlf2	myeloid leukemia factor 2	0.017
Commd4	COMM domain containing 4	0.017
Ostf1	osteoclast stimulating factor 1	0.016
Abhd12	abhydrolase domain containing 12	0.016
Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1	0.016
Lrp1b	low density lipoprotein-related protein 1B (deleted in tumors)	0.016
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.016
Copg	coatomer protein complex, subunit gamma	0.016
Prex1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.016
Rhoa	ras homolog gene family, member A	0.016
Ftl1	ferritin light chain 1	0.016
Bax	BCL2-associated X protein	0.016
Fyn	Fyn proto-oncogene	0.015
Anxa5	annexin A5	0.015
Btk	Bruton agammaglobulinemia tyrosine kinase	0.015
Ptk2	PTK2 protein tyrosine kinase 2	0.015
Cdk2ap2	CDK2-associated protein 2	0.015
Fam164a	family with sequence similarity 164, member A	0.015
Ctnnb1	catenin (cadherin associated protein), beta 1	0.015
Itgb2	integrin beta 2	0.015
Dock2	dedicator of cyto-kinesis 2	0.015
Ogfr	opioid growth factor receptor	0.015
Ncf4	neutrophil cytosolic factor 4	0.015
Vav1	vav 1 oncogene	0.015
Thy1	thymus cell antigen 1, theta	0.015
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.015
AI413582	expressed sequence AI413582	0.015
Lrrc33	leucine rich repeat containing 33	0.014
Lgmn	legumain	0.014
Cfp	complement factor properdin	0.014
Tagln2	transgelin 2	0.014
Pkm2	pyruvate kinase, muscle	0.014
Eif6	eukaryotic translation initiation factor 6	0.014
Lrp10	low-density lipoprotein receptor-related protein 10	0.014
Unc93b1	unc-93 homolog B1 (C. elegans)	0.014
Nbea	neurobeachin	0.014
Dstn	destrin	0.014
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.014
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.014
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.014
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.014
Pef1	penta-EF hand domain containing 1	0.014
Mpdu1	mannose-P-dolichol utilization defect 1	0.014
Myo1f	myosin IF	0.013
G6pdx	glucose-6-phosphate dehydrogenase X-linked	0.013
Capn2	calpain 2	0.013
Lrp4	low density lipoprotein receptor-related protein 4	0.013
Tradd	TNFRSF1A-associated via death domain	0.013
Wasf1	WASP family 1	0.013	Human
Rab3a	RAB3A, member RAS oncogene family	0.013
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.013
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.013
Fnbp1l	formin binding protein 1-like	0.013
Abr	active BCR-related gene	0.013
Msn	moesin	0.013
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.013
Grn	granulin	0.013
Anapc2	anaphase promoting complex subunit 2	0.013
Zfp326	zinc finger protein 326	0.013
Ncf2	neutrophil cytosolic factor 2	0.013
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.013
Gm5506	predicted gene 5506	0.012
Fcho1	FCH domain only 1	0.012
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.012
Cnn2	calponin 2	0.012
Coro7	coronin 7	0.012	Yeast
Flii	flightless I homolog (Drosophila)	0.012
Mvp	major vault protein	0.012
Tubb4	tubulin, beta 4	0.012
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.012
Prr13	proline rich 13	0.012
Akap11	A kinase (PRKA) anchor protein 11	0.012
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.012
Cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.012
Lrmp	lymphoid-restricted membrane protein	0.012
Rab7	RAB7, member RAS oncogene family	0.012
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.012
Dock9	dedicator of cytokinesis 9	0.012
Zranb2	zinc finger, RAN-binding domain containing 2	0.012
Cope	coatomer protein complex, subunit epsilon	0.012
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.012
Tjp2	tight junction protein 2	0.012
Nckap1l	NCK associated protein 1 like	0.012
Sar1a	SAR1 gene homolog A (S. cerevisiae)	0.012
Cd52	CD52 antigen	0.012
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.012
Ap1g2	adaptor protein complex AP-1, gamma 2 subunit	0.012
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.011
Psme2	proteasome (prosome, macropain) 28 subunit, beta	0.011
Evi5	ecotropic viral integration site 5	0.011
Papss1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	0.011
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.011
Rtn4	reticulon 4	0.011
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.011
Rgs19	regulator of G-protein signaling 19	0.011
Amdhd2	amidohydrolase domain containing 2	0.011
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.011
Spg21	spastic paraplegia 21 homolog (human)	0.011
Lrrc59	leucine rich repeat containing 59	0.011
Fam105a	family with sequence similarity 105, member A	0.011
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.011
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.011
Rnpep	arginyl aminopeptidase (aminopeptidase B)	0.011
Gba	glucosidase, beta, acid	0.011
Hn1	hematological and neurological expressed sequence 1	0.011
Upf3b	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.011
Cdc42se2	CDC42 small effector 2	0.011
Rgs14	regulator of G-protein signaling 14	0.011
Git2	G protein-coupled receptor kinase-interactor 2	0.010
Aup1	ancient ubiquitous protein 1	0.010
Maea	macrophage erythroblast attacher	0.010
Evl	Ena-vasodilator stimulated phosphoprotein	0.010
Irf8	interferon regulatory factor 8	0.010
Actn1	actinin, alpha 1	0.010
Pfkl	phosphofructokinase, liver, B-type	0.010
Lck	lymphocyte protein tyrosine kinase	0.010
Xpnpep1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.010
Arpc1a	actin related protein 2/3 complex, subunit 1A	0.010
Smap2	stromal membrane-associated GTPase-activating protein 2	0.010
Tmsb10	thymosin, beta 10	0.010
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.010
Npc2	Niemann Pick type C2	0.010
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.010