IMP

Process View

Mus musculus

5 genes annotated in mouse

positive regulation of macrophage chemotaxis

Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of macrophage chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of macrophage chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	0.993
Msr1	macrophage scavenger receptor 1	0.951
Ccr1	chemokine (C-C motif) receptor 1	0.804
Il1b	interleukin 1 beta	0.717
Fcgr1	Fc receptor, IgG, high affinity I	0.690
Cd44	CD44 antigen	0.636
Ccl3	chemokine (C-C motif) ligand 3	0.518
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.516
Clec4e	C-type lectin domain family 4, member e	0.508
Cybb	cytochrome b-245, beta polypeptide	0.479
Cdh5	cadherin 5	0.463
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.437
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.435
Clec4d	C-type lectin domain family 4, member d	0.417
Slfn4	schlafen 4	0.395
Il1rn	interleukin 1 receptor antagonist	0.357
Csf1	colony stimulating factor 1 (macrophage)	0.354
C3ar1	complement component 3a receptor 1	0.352
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.338
Fpr1	formyl peptide receptor 1	0.329	Mouse
Ccr5	chemokine (C-C motif) receptor 5	0.302
C5ar1	complement component 5a receptor 1	0.279
Tlr4	toll-like receptor 4	0.275
Selp	selectin, platelet	0.244
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.235
Cd14	CD14 antigen	0.214
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.200
Thbs1	thrombospondin 1	0.194
Slfn1	schlafen 1	0.194
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.189
Ush1g	Usher syndrome 1G homolog (human)	0.185
Ush1c	Usher syndrome 1C homolog (human)	0.174
Saa3	serum amyloid A 3	0.159
F10	coagulation factor X	0.154
Lyz2	lysozyme 2	0.149
Il1a	interleukin 1 alpha	0.147
Gm14548	predicted gene 14548	0.142
Lox	lysyl oxidase	0.139
Ccl7	chemokine (C-C motif) ligand 7	0.135
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.134
Mmp8	matrix metallopeptidase 8	0.132
Ccl9	chemokine (C-C motif) ligand 9	0.129
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.129
Mmp9	matrix metallopeptidase 9	0.126
Tlr2	toll-like receptor 2	0.125
Marco	macrophage receptor with collagenous structure	0.118
Dab2	disabled homolog 2 (Drosophila)	0.118
Has1	hyaluronan synthase1	0.115
Mdm2	transformed mouse 3T3 cell double minute 2	0.113
Fcgr4	Fc receptor, IgG, low affinity IV	0.102
Grxcr1	glutaredoxin, cysteine rich 1	0.100
Col1a1	collagen, type I, alpha 1	0.098
Cxcl2	chemokine (C-X-C motif) ligand 2	0.098
Ccl4	chemokine (C-C motif) ligand 4	0.087
Osmr	oncostatin M receptor	0.086
Cx3cr1	chemokine (C-X3-C) receptor 1	0.085
Nos3	nitric oxide synthase 3, endothelial cell	0.080
Tbxas1	thromboxane A synthase 1, platelet	0.078
AF251705	cDNA sequence AF251705	0.076
Clec4a2	C-type lectin domain family 4, member a2	0.075
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.072
Col8a1	collagen, type VIII, alpha 1	0.071
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.069
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.067
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.066
Itgam	integrin alpha M	0.066
Aoah	acyloxyacyl hydrolase	0.058
Tyrobp	TYRO protein tyrosine kinase binding protein	0.058
Il6	interleukin 6	0.057
Ncf1	neutrophil cytosolic factor 1	0.057
Irg1	immunoresponsive gene 1	0.053
Ccl8	chemokine (C-C motif) ligand 8	0.050
Ifitm6	interferon induced transmembrane protein 6	0.049
Plaur	plasminogen activator, urokinase receptor	0.046
Ccl6	chemokine (C-C motif) ligand 6	0.046
Folr2	folate receptor 2 (fetal)	0.045
Sykb	spleen tyrosine kinase	0.044
Il1r1	interleukin 1 receptor, type I	0.044
Mmp3	matrix metallopeptidase 3	0.044
Whrn	whirlin	0.042
Ccl12	chemokine (C-C motif) ligand 12	0.040
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.040
Ch25h	cholesterol 25-hydroxylase	0.040
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.039
Lcp2	lymphocyte cytosolic protein 2	0.039
Chi3l3	chitinase 3-like 3	0.038
Clec4n	C-type lectin domain family 4, member n	0.037
Thbs2	thrombospondin 2	0.035	Mouse
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.034
Tgfb1	transforming growth factor, beta 1	0.033
Mmp12	matrix metallopeptidase 12	0.032
Gdf15	growth differentiation factor 15	0.031
Cd180	CD180 antigen	0.030
Pcdh15	protocadherin 15	0.030
Mx2	myxovirus (influenza virus) resistance 2	0.030
Itgax	integrin alpha X	0.028
Slpi	secretory leukocyte peptidase inhibitor	0.027
Sirpa	signal-regulatory protein alpha	0.026
Cdh23	cadherin 23 (otocadherin)	0.026
Cd86	CD86 antigen	0.026
C1qb	complement component 1, q subcomponent, beta polypeptide	0.026
F7	coagulation factor VII	0.025
Myo7a	myosin VIIA	0.025
Vcam1	vascular cell adhesion molecule 1	0.025
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.024
Itgal	integrin alpha L	0.023
Acvrl1	activin A receptor, type II-like 1	0.023
Adam8	a disintegrin and metallopeptidase domain 8	0.023
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.023
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.022
Nos2	nitric oxide synthase 2, inducible	0.022
Hck	hemopoietic cell kinase	0.021
Itgb2l	integrin beta 2-like	0.021
Selplg	selectin, platelet (p-selectin) ligand	0.019
Htra3	HtrA serine peptidase 3	0.019
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.019
Adcy4	adenylate cyclase 4	0.019
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.019
Icam1	intercellular adhesion molecule 1	0.019
Fcgr3	Fc receptor, IgG, low affinity III	0.018
Hp	haptoglobin	0.018
Cd300ld	CD300 molecule-like family member d	0.018
Ctsk	cathepsin K	0.017
Tnc	tenascin C	0.017
Mpeg1	macrophage expressed gene 1	0.016
Cxcl1	chemokine (C-X-C motif) ligand 1	0.015
Mc3r	melanocortin 3 receptor	0.015
Tcfec	transcription factor EC	0.014
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.014
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.014
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.013
Sfpi1	SFFV proviral integration 1	0.013
Il10	interleukin 10	0.013
Gpr98	G protein-coupled receptor 98	0.013
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.013
Tlr8	toll-like receptor 8	0.012
Myo1f	myosin IF	0.012
Cxcr2	chemokine (C-X-C motif) receptor 2	0.012
Fcna	ficolin A	0.012
Hmox1	heme oxygenase (decycling) 1	0.012
Clec7a	C-type lectin domain family 7, member a	0.012
C78513	EST C78513	0.011
Brs3	bombesin-like receptor 3	0.011
Myo15	myosin XV	0.011
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.011
Lcn2	lipocalin 2	0.011
Cxcl13	chemokine (C-X-C motif) ligand 13	0.011
Expi	extracellular proteinase inhibitor	0.011
Itgb2	integrin beta 2	0.011
Plau	plasminogen activator, urokinase	0.010
Timp1	tissue inhibitor of metalloproteinase 1	0.010
Mmp13	matrix metallopeptidase 13	0.010
Il18rap	interleukin 18 receptor accessory protein	0.010
Il10ra	interleukin 10 receptor, alpha	0.010
Gab2	growth factor receptor bound protein 2-associated protein 2	0.010