IMP

Process View

Mus musculus

18 genes annotated in mouse

adrenal gland development

The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "adrenal gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "adrenal gland development" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.982
Esr1	estrogen receptor 1 (alpha)	0.889
Kiss1	KiSS-1 metastasis-suppressor	0.684
Nodal	nodal	0.317
Sall4	sal-like 4 (Drosophila)	0.280
Notch2	Notch gene homolog 2 (Drosophila)	0.272
Kdr	kinase insert domain protein receptor	0.253	Mouse
Vegfa	vascular endothelial growth factor A	0.234
Ctnnb1	catenin (cadherin associated protein), beta 1	0.221
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.199
Kif3a	kinesin family member 3A	0.180
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.163
Tgfb1	transforming growth factor, beta 1	0.149
Nanog	Nanog homeobox	0.140
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.136
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.126
Rb1	retinoblastoma 1	0.125
Apc	adenomatosis polyposis coli	0.121
Ren1	renin 1 structural	0.119
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.100
Nab2	Ngfi-A binding protein 2	0.098
Ghr	growth hormone receptor	0.097
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.095
Egr1	early growth response 1	0.095	Mouse
Ar	androgen receptor	0.087
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.086
Gata4	GATA binding protein 4	0.085
Drd2	dopamine receptor D2	0.083
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.083
Nos3	nitric oxide synthase 3, endothelial cell	0.080
Pten	phosphatase and tensin homolog	0.078
Lyz2	lysozyme 2	0.075
Thrb	thyroid hormone receptor beta	0.074
Tgfbr2	transforming growth factor, beta receptor II	0.072
Pomc	pro-opiomelanocortin-alpha	0.071
Shh	sonic hedgehog	0.069
Lhx3	LIM homeobox protein 3	0.063
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.061
Notch1	Notch gene homolog 1 (Drosophila)	0.061
Tcf21	transcription factor 21	0.060
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.058
Sall1	sal-like 1 (Drosophila)	0.054	Human
Esr2	estrogen receptor 2 (beta)	0.050
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.049
Lhb	luteinizing hormone beta	0.049
Prlr	prolactin receptor	0.047
Csf1	colony stimulating factor 1 (macrophage)	0.046
Pou5f1	POU domain, class 5, transcription factor 1	0.045
Vangl2	vang-like 2 (van gogh, Drosophila)	0.044
Amhr2	anti-Mullerian hormone type 2 receptor	0.043
Star	steroidogenic acute regulatory protein	0.041
Esrrb	estrogen related receptor, beta	0.040
Fshr	follicle stimulating hormone receptor	0.039
Hand1	heart and neural crest derivatives expressed transcript 1	0.038
Dhh	desert hedgehog	0.036
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.036
Meis2	Meis homeobox 2	0.034
Bdkrb2	bradykinin receptor, beta 2	0.032
Flt4	FMS-like tyrosine kinase 4	0.032	Mouse
Jun	Jun oncogene	0.031
Fos	FBJ osteosarcoma oncogene	0.031
Aqp8	aquaporin 8	0.030
Acvr1	activin A receptor, type 1	0.029
Plcg1	phospholipase C, gamma 1	0.029
Onecut1	one cut domain, family member 1	0.029
Meis1	Meis homeobox 1	0.029
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.028
Apob	apolipoprotein B	0.028
Eng	endoglin	0.028
Irs2	insulin receptor substrate 2	0.027
Fgf8	fibroblast growth factor 8	0.026
Wwox	WW domain-containing oxidoreductase	0.026
Pdgfb	platelet derived growth factor, B polypeptide	0.026
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.025
Ptgs2	prostaglandin-endoperoxide synthase 2	0.025
Amh	anti-Mullerian hormone	0.025
Pparg	peroxisome proliferator activated receptor gamma	0.025
Cdhr5	cadherin-related family member 5	0.025
Cga	glycoprotein hormones, alpha subunit	0.025
Ptk2	PTK2 protein tyrosine kinase 2	0.024
Agtr1a	angiotensin II receptor, type 1a	0.024
Adra2b	adrenergic receptor, alpha 2b	0.024
Kitl	kit ligand	0.024
Cdh5	cadherin 5	0.024
Hand2	heart and neural crest derivatives expressed transcript 2	0.023
Fgf4	fibroblast growth factor 4	0.023
Kiss1r	KISS1 receptor	0.022
Tyrobp	TYRO protein tyrosine kinase binding protein	0.022
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.022
Bcl2	B-cell leukemia/lymphoma 2	0.022
Gata6	GATA binding protein 6	0.022
Sall3	sal-like 3 (Drosophila)	0.022
Braf	Braf transforming gene	0.021
Bglap	bone gamma carboxyglutamate protein	0.021
Tat	tyrosine aminotransferase	0.020
Cxcl12	chemokine (C-X-C motif) ligand 12	0.020
Igf2	insulin-like growth factor 2	0.020
Pdx1	pancreatic and duodenal homeobox 1	0.020
Itgb3	integrin beta 3	0.019
Fgf3	fibroblast growth factor 3	0.019
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.019
Gnrhr	gonadotropin releasing hormone receptor	0.019
Prkcc	protein kinase C, gamma	0.019
Ldlr	low density lipoprotein receptor	0.019
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.019
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.018
Efnb2	ephrin B2	0.018
Pitx2	paired-like homeodomain transcription factor 2	0.018
Egfr	epidermal growth factor receptor	0.018
Pgr	progesterone receptor	0.018	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.018
Vegfc	vascular endothelial growth factor C	0.018
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.018
Smyd1	SET and MYND domain containing 1	0.018
Pde8b	phosphodiesterase 8B	0.018
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.018
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.017
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.017
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.017
Hgd	homogentisate 1, 2-dioxygenase	0.017
Adra1b	adrenergic receptor, alpha 1b	0.017
Sox7	SRY-box containing gene 7	0.017
Junb	Jun-B oncogene	0.017
Dnahc11	dynein, axonemal, heavy chain 11	0.017
Agrp	agouti related protein	0.017
Ahr	aryl-hydrocarbon receptor	0.017
Sgpl1	sphingosine phosphate lyase 1	0.017
Hes1	hairy and enhancer of split 1 (Drosophila)	0.016
Ptch1	patched homolog 1	0.016
Cd247	CD247 antigen	0.016
Car5a	carbonic anhydrase 5a, mitochondrial	0.016
Nf1	neurofibromatosis 1	0.016
Nrp1	neuropilin 1	0.016
Epas1	endothelial PAS domain protein 1	0.016
Nab1	Ngfi-A binding protein 1	0.015
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.015	Mouse
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.015
Cbl	Casitas B-lineage lymphoma	0.015
Tbx18	T-box18	0.015
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.015
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.015
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.015
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.015
Bmp1	bone morphogenetic protein 1	0.015
Fstl1	follistatin-like 1	0.014
Mc2r	melanocortin 2 receptor	0.014	Zebrafish
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.014
Dll1	delta-like 1 (Drosophila)	0.014
Gnrh1	gonadotropin releasing hormone 1	0.014
Il6st	interleukin 6 signal transducer	0.014
Prop1	paired like homeodomain factor 1	0.014
Pknox2	Pbx/knotted 1 homeobox 2	0.014
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.014
Ihh	Indian hedgehog	0.014
Adm	adrenomedullin	0.014
Stat3	signal transducer and activator of transcription 3	0.014
Vhl	von Hippel-Lindau tumor suppressor	0.014
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.013
Fbn2	fibrillin 2	0.013
Tshr	thyroid stimulating hormone receptor	0.013
Rax	retina and anterior neural fold homeobox	0.013
Zic3	zinc finger protein of the cerebellum 3	0.013
Hoxa6	homeobox A6	0.013
Ret	ret proto-oncogene	0.013
Dll4	delta-like 4 (Drosophila)	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Crh	corticotropin releasing hormone	0.013
Mybpc3	myosin binding protein C, cardiac	0.013
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.013	Rat
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.013
Pcdh12	protocadherin 12	0.013
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.013
Kcnk3	potassium channel, subfamily K, member 3	0.013
Gdf7	growth differentiation factor 7	0.013
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
Lrp1	low density lipoprotein receptor-related protein 1	0.012
Ptafr	platelet-activating factor receptor	0.012
Ednrb	endothelin receptor type B	0.012
Tmem204	transmembrane protein 204	0.012
Sfrp5	secreted frizzled-related sequence protein 5	0.012
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.012
Nhlh2	nescient helix loop helix 2	0.012
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.012
Gata1	GATA binding protein 1	0.012
Fam167b	family with sequence similarity 167, member B	0.012
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.012
Kit	kit oncogene	0.012	Mouse
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.012
Neurog2	neurogenin 2	0.012
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.011
Ptprb	protein tyrosine phosphatase, receptor type, B	0.011
Gdf1	growth differentiation factor 1	0.011
Orm3	orosomucoid 3	0.011
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.011	Rat
Nos2	nitric oxide synthase 2, inducible	0.011
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.011
Sntb1	syntrophin, basic 1	0.011
Tbx3	T-box 3	0.011
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.011
Apoa5	apolipoprotein A-V	0.011	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.011
Hoxd11	homeobox D11	0.011
Inhbc	inhibin beta-C	0.011
Nos1	nitric oxide synthase 1, neuronal	0.011
F2	coagulation factor II	0.011
Lep	leptin	0.011
Aldob	aldolase B, fructose-bisphosphate	0.011
Prox1	prospero-related homeobox 1	0.011
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.011
Kl	klotho	0.011
Hoxb8	homeobox B8	0.011
Nog	noggin	0.011
Pax8	paired box gene 8	0.011
Psen1	presenilin 1	0.011
Nkx6-1	NK6 homeobox 1	0.010
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.010
Itga3	integrin alpha 3	0.010
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.010
Rhbdf1	rhomboid family 1 (Drosophila)	0.010
Lhx9	LIM homeobox protein 9	0.010
Il1f5	interleukin 1 family, member 5 (delta)	0.010
Tead4	TEA domain family member 4	0.010
Col4a3	collagen, type IV, alpha 3	0.010
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.010
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.010
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.010
Ppyr1	pancreatic polypeptide receptor 1	0.010