IMP

Process View

Mus musculus

13 genes annotated in mouse

dna templated transcription initiation

Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna templated transcription initiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dna templated transcription initiation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax8	paired box gene 8	0.333
Gli2	GLI-Kruppel family member GLI2	0.324
Rarg	retinoic acid receptor, gamma	0.206
Vax1	ventral anterior homeobox containing gene 1	0.191
Hand2	heart and neural crest derivatives expressed transcript 2	0.162
Wnt3a	wingless-related MMTV integration site 3A	0.158	Mouse
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.152
Hand1	heart and neural crest derivatives expressed transcript 1	0.151
Cav1	caveolin 1, caveolae protein	0.150
Fgf8	fibroblast growth factor 8	0.149
Zic2	zinc finger protein of the cerebellum 2	0.147	Worm
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.133
Ghr	growth hormone receptor	0.131
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.127	Yeast
Ncoa6	nuclear receptor coactivator 6	0.121	Human
Tcf3	transcription factor 3	0.119	Mouse
Stat2	signal transducer and activator of transcription 2	0.109
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.106
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.089
Tbp	TATA box binding protein	0.086
T	brachyury	0.086
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.084
Pax2	paired box gene 2	0.083
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.075
Scaf11	SR-related CTD-associated factor 11	0.075
Igh	immunoglobulin heavy chain complex	0.074
Gata4	GATA binding protein 4	0.074
Trp53	transformation related protein 53	0.073
Fgf3	fibroblast growth factor 3	0.072
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.068
Zic1	zinc finger protein of the cerebellum 1	0.066	Worm
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.063
Lhx1	LIM homeobox protein 1	0.062
Mesp1	mesoderm posterior 1	0.060
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.059
Foxe1	forkhead box E1	0.050
Nkx6-1	NK6 homeobox 1	0.050
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.048
Lhx5	LIM homeobox protein 5	0.048
Tbx1	T-box 1	0.046
Chuk	conserved helix-loop-helix ubiquitous kinase	0.044
Nodal	nodal	0.043
Uba7	ubiquitin-like modifier activating enzyme 7	0.041
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.040
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.039
Hoxa13	homeobox A13	0.037
Pou3f3	POU domain, class 3, transcription factor 3	0.037
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.037	Yeast
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.036
Fgfr1	fibroblast growth factor receptor 1	0.036
Srebf2	sterol regulatory element binding factor 2	0.036
Shh	sonic hedgehog	0.035
Pitx2	paired-like homeodomain transcription factor 2	0.034
Ntf3	neurotrophin 3	0.034
Barx1	BarH-like homeobox 1	0.030
2610101N10Rik	RIKEN cDNA 2610101N10 gene	0.029
Cct5	chaperonin containing Tcp1, subunit 5 (epsilon)	0.029
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.029
Otx2	orthodenticle homolog 2 (Drosophila)	0.029
Id1	inhibitor of DNA binding 1	0.028
N6amt2	N-6 adenine-specific DNA methyltransferase 2 (putative)	0.028
Esrrb	estrogen related receptor, beta	0.028
Ifnar2	interferon (alpha and beta) receptor 2	0.027
Max	Max protein	0.026
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.026
Trp63	transformation related protein 63	0.026
Traf6	TNF receptor-associated factor 6	0.025
Cirh1a	cirrhosis, autosomal recessive 1A (human)	0.025
Tcerg1	transcription elongation regulator 1 (CA150)	0.025
Id2	inhibitor of DNA binding 2	0.025
Stag1	stromal antigen 1	0.024
Wnt10b	wingless related MMTV integration site 10b	0.024
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.024
Tada2a	transcriptional adaptor 2A	0.024
Hoxd1	homeobox D1	0.024
Sfpi1	SFFV proviral integration 1	0.023
Nsun2	NOL1/NOP2/Sun domain family member 2	0.023
Fzd10	frizzled homolog 10 (Drosophila)	0.023
Sox1	SRY-box containing gene 1	0.023
Foxc2	forkhead box C2	0.022
Nog	noggin	0.022
Pou5f1	POU domain, class 5, transcription factor 1	0.022
Creb1	cAMP responsive element binding protein 1	0.022	Rat
Baz1b	bromodomain adjacent to zinc finger domain, 1B	0.022
Cct7	chaperonin containing Tcp1, subunit 7 (eta)	0.022
Pou3f2	POU domain, class 3, transcription factor 2	0.022
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.022
Wnt3	wingless-related MMTV integration site 3	0.022	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.021
Med28	mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)	0.021
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.021
Hoxd13	homeobox D13	0.021
Pax9	paired box gene 9	0.021
Brd8	bromodomain containing 8	0.021
Fgf15	fibroblast growth factor 15	0.021
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.021
Fgf5	fibroblast growth factor 5	0.020
Foxb1	forkhead box B1	0.020
Tlx3	T-cell leukemia, homeobox 3	0.020
Pou2f2	POU domain, class 2, transcription factor 2	0.020
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.020
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.019
Eif2b4	eukaryotic translation initiation factor 2B, subunit 4 delta	0.019
Wnt2b	wingless related MMTV integration site 2b	0.019	Mouse
Kl	klotho	0.019
Rarb	retinoic acid receptor, beta	0.019
Lrp6	low density lipoprotein receptor-related protein 6	0.018
En1	engrailed 1	0.018
Hoxd11	homeobox D11	0.018
Id3	inhibitor of DNA binding 3	0.018
Pcm1	pericentriolar material 1	0.018
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.018
Scn5a	sodium channel, voltage-gated, type V, alpha	0.018
Ikzf1	IKAROS family zinc finger 1	0.018
Sall3	sal-like 3 (Drosophila)	0.018
Wnt6	wingless-related MMTV integration site 6	0.017	Mouse
Fbrs	fibrosin	0.017
Tbcb	tubulin folding cofactor B	0.017
Bcl3	B-cell leukemia/lymphoma 3	0.017
Med1	mediator complex subunit 1	0.017	Human
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.017
Cfc1	cripto, FRL-1, cryptic family 1	0.017
Irf9	interferon regulatory factor 9	0.017	Mouse
Drg1	developmentally regulated GTP binding protein 1	0.017
Npas1	neuronal PAS domain protein 1	0.017
Socs1	suppressor of cytokine signaling 1	0.017
Wnt4	wingless-related MMTV integration site 4	0.017	Mouse
Otp	orthopedia homolog (Drosophila)	0.016
Hoxa2	homeobox A2	0.016
Efnb2	ephrin B2	0.016
Usp39	ubiquitin specific peptidase 39	0.016
Fut7	fucosyltransferase 7	0.016
Irf8	interferon regulatory factor 8	0.016
Sfn	stratifin	0.016
Nfya	nuclear transcription factor-Y alpha	0.016
Trp73	transformation related protein 73	0.016
Duox2	dual oxidase 2	0.016
Col22a1	collagen, type XXII, alpha 1	0.016
Insm1	insulinoma-associated 1	0.016
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.016
Gdnf	glial cell line derived neurotrophic factor	0.016
Tbx5	T-box 5	0.016
Atp11c	ATPase, class VI, type 11C	0.015
Rnf2	ring finger protein 2	0.015
Prpf8	pre-mRNA processing factor 8	0.015
Olig2	oligodendrocyte transcription factor 2	0.015
Tal1	T-cell acute lymphocytic leukemia 1	0.015
Dlx1	distal-less homeobox 1	0.015
Cd40	CD40 antigen	0.015
Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)	0.015
Btbd17	BTB (POZ) domain containing 17	0.015
Bmi1	Bmi1 polycomb ring finger oncogene	0.015
Zbtb22	zinc finger and BTB domain containing 22	0.015
Exosc10	exosome component 10	0.015
Ep300	E1A binding protein p300	0.015
Prkcd	protein kinase C, delta	0.015
Lef1	lymphoid enhancer binding factor 1	0.014
Pkn2	protein kinase N2	0.014
Ccnt1	cyclin T1	0.014
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.014
Gli1	GLI-Kruppel family member GLI1	0.014
Fgf10	fibroblast growth factor 10	0.014
Acvr1	activin A receptor, type 1	0.014
Xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.014
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.014
Irf4	interferon regulatory factor 4	0.014	Mouse
Gata6	GATA binding protein 6	0.014
Psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.014
Pax5	paired box gene 5	0.014
Nudc	nuclear distribution gene C homolog (Aspergillus)	0.014
Zic3	zinc finger protein of the cerebellum 3	0.013	Worm
Emx2	empty spiracles homolog 2 (Drosophila)	0.013
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.013
Ep400	E1A binding protein p400	0.013
Ttc7	tetratricopeptide repeat domain 7	0.013
Mpv17	MpV17 mitochondrial inner membrane protein	0.013
Rara	retinoic acid receptor, alpha	0.013
Fgf17	fibroblast growth factor 17	0.013
Tcf15	transcription factor 15	0.013
Irgm2	immunity-related GTPase family M member 2	0.013
Hcfc1	host cell factor C1	0.013
Psmb6	proteasome (prosome, macropain) subunit, beta type 6	0.013
Zfp771	zinc finger protein 771	0.013
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.012
Foxi1	forkhead box I1	0.012
Hoxa4	homeobox A4	0.012
Trrap	transformation/transcription domain-associated protein	0.012
Strap	serine/threonine kinase receptor associated protein	0.012
Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.012
Sox3	SRY-box containing gene 3	0.012
Pknox1	Pbx/knotted 1 homeobox	0.012
Foxn4	forkhead box N4	0.012
Tbpl1	TATA box binding protein-like 1	0.012
Adsl	adenylosuccinate lyase	0.012
Stat1	signal transducer and activator of transcription 1	0.012
Sox9	SRY-box containing gene 9	0.012
Amh	anti-Mullerian hormone	0.012
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.012
Smndc1	survival motor neuron domain containing 1	0.012
Psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.012
Foxc1	forkhead box C1	0.012
Gipc3	GIPC PDZ domain containing family, member 3	0.012
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.011
Scaf4	SR-related CTD-associated factor 4	0.011
Arid1a	AT rich interactive domain 1A (SWI-like)	0.011
Ctnnb1	catenin (cadherin associated protein), beta 1	0.011
Ube2e1	ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast)	0.011
Ncoa3	nuclear receptor coactivator 3	0.011
Eif3g	eukaryotic translation initiation factor 3, subunit G	0.011
Brd3	bromodomain containing 3	0.011
Pml	promyelocytic leukemia	0.011
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.011
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.011
Amhr2	anti-Mullerian hormone type 2 receptor	0.011
Bicc1	bicaudal C homolog 1 (Drosophila)	0.011
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.011
Rfx7	regulatory factor X, 7	0.011
Arnt	aryl hydrocarbon receptor nuclear translocator	0.011
Siah1b	seven in absentia 1B	0.011
Pgr	progesterone receptor	0.011
Iqcb1	IQ calmodulin-binding motif containing 1	0.011
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.011
Dlx5	distal-less homeobox 5	0.011
Siva1	SIVA1, apoptosis-inducing factor	0.011
Crebbp	CREB binding protein	0.011
Rhcg	Rhesus blood group-associated C glycoprotein	0.011
Sf3b3	splicing factor 3b, subunit 3	0.011
Hif1a	hypoxia inducible factor 1, alpha subunit	0.011
Cand1	cullin associated and neddylation disassociated 1	0.011	Rat
Hoxd3	homeobox D3	0.011
Fzd8	frizzled homolog 8 (Drosophila)	0.011
Rsad2	radical S-adenosyl methionine domain containing 2	0.011
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.011
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.011
Smc6	structural maintenance of chromosomes 6	0.011
Cbll1	Casitas B-lineage lymphoma-like 1	0.011
Ugt8a	UDP galactosyltransferase 8A	0.010
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.010
Aicda	activation-induced cytidine deaminase	0.010
Rpa1	replication protein A1	0.010
Adra2b	adrenergic receptor, alpha 2b	0.010
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.010
Trim21	tripartite motif-containing 21	0.010
Dlx6	distal-less homeobox 6	0.010
Vangl2	vang-like 2 (van gogh, Drosophila)	0.010
Nup93	nucleoporin 93	0.010
Vstm2b	V-set and transmembrane domain containing 2B	0.010
Etv2	ets variant gene 2	0.010
Gal3st1	galactose-3-O-sulfotransferase 1	0.010
Igtp	interferon gamma induced GTPase	0.010
Zfp62	zinc finger protein 62	0.010