IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of metanephric glomerulus development

Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of metanephric glomerulus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of metanephric glomerulus development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.983
C1qc	complement component 1, q subcomponent, C chain	0.981	Mouse
Ren1	renin 1 structural	0.960
Pax3	paired box gene 3	0.948
Lhx1	LIM homeobox protein 1	0.815
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.664	Mouse
Wt1	Wilms tumor 1 homolog	0.653
Ret	ret proto-oncogene	0.637
Ctss	cathepsin S	0.608
Agtr1a	angiotensin II receptor, type 1a	0.597	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.597
Lepr	leptin receptor	0.566
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.476
Shh	sonic hedgehog	0.435
Tyrobp	TYRO protein tyrosine kinase binding protein	0.418
Chd7	chromodomain helicase DNA binding protein 7	0.382
C1qb	complement component 1, q subcomponent, beta polypeptide	0.370	Mouse
Wnt9b	wingless-type MMTV integration site 9B	0.300
Ptgs2	prostaglandin-endoperoxide synthase 2	0.274
Emx2	empty spiracles homolog 2 (Drosophila)	0.263
Fgfr2	fibroblast growth factor receptor 2	0.253
Hoxa11	homeobox A11	0.233
Pax8	paired box gene 8	0.229	Mouse
Fgf10	fibroblast growth factor 10	0.225
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.215
Otx1	orthodenticle homolog 1 (Drosophila)	0.196
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.194
Bcl2	B-cell leukemia/lymphoma 2	0.193
Apoe	apolipoprotein E	0.161
Gbx2	gastrulation brain homeobox 2	0.158
Hoxd11	homeobox D11	0.149
Umod	uromodulin	0.144
Col4a3	collagen, type IV, alpha 3	0.144
Hoxa1	homeobox A1	0.144
Aif1	allograft inflammatory factor 1	0.141
Tbx10	T-box 10	0.141
Nos3	nitric oxide synthase 3, endothelial cell	0.140
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.127
Csf1r	colony stimulating factor 1 receptor	0.123
Ly86	lymphocyte antigen 86	0.122
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.120
Foxi1	forkhead box I1	0.119
Bdkrb2	bradykinin receptor, beta 2	0.112	Mouse
Fgf3	fibroblast growth factor 3	0.109
Agtr2	angiotensin II receptor, type 2	0.107
T	brachyury	0.089
Igl	immunoglobulin lambda chain complex	0.085
Zeb1	zinc finger E-box binding homeobox 1	0.085
Sox10	SRY-box containing gene 10	0.084
Ar	androgen receptor	0.084
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.080
Psen1	presenilin 1	0.077
Pou4f2	POU domain, class 4, transcription factor 2	0.075
Kiss1	KiSS-1 metastasis-suppressor	0.075
Duox2	dual oxidase 2	0.070
Vangl2	vang-like 2 (van gogh, Drosophila)	0.069
Eln	elastin	0.068
Drd2	dopamine receptor D2	0.065
Gata3	GATA binding protein 3	0.064
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.063
Lhx3	LIM homeobox protein 3	0.060
Nos2	nitric oxide synthase 2, inducible	0.059
Mrc1	mannose receptor, C type 1	0.058
Foxe1	forkhead box E1	0.057
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.056
Nos1	nitric oxide synthase 1, neuronal	0.056
Gdf11	growth differentiation factor 11	0.054
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.054
Rarg	retinoic acid receptor, gamma	0.048
Lef1	lymphoid enhancer binding factor 1	0.046
Hmx3	H6 homeobox 3	0.046
En1	engrailed 1	0.045
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.041
Hoxb3	homeobox B3	0.041
Dusp1	dual specificity phosphatase 1	0.040
Otx2	orthodenticle homolog 2 (Drosophila)	0.039
Vdr	vitamin D receptor	0.039
Slc12a1	solute carrier family 12, member 1	0.038
Eya1	eyes absent 1 homolog (Drosophila)	0.038
Nrxn3	neurexin III	0.037
Aqp2	aquaporin 2	0.037
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.036
Pld4	phospholipase D family, member 4	0.035
H2-Eb1	histocompatibility 2, class II antigen E beta	0.035
Vegfa	vascular endothelial growth factor A	0.035
Lyz1	lysozyme 1	0.034
Agtrap	angiotensin II, type I receptor-associated protein	0.033
Rarb	retinoic acid receptor, beta	0.033
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.032
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.032
Fos	FBJ osteosarcoma oncogene	0.031
Gucy2e	guanylate cyclase 2e	0.031
Crhr1	corticotropin releasing hormone receptor 1	0.030
Egr2	early growth response 2	0.030
Cav1	caveolin 1, caveolae protein	0.029
Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.028
Kiss1r	KISS1 receptor	0.028
Gdnf	glial cell line derived neurotrophic factor	0.026
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.026
Olfr90	olfactory receptor 90	0.026
Rpe65	retinal pigment epithelium 65	0.025
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.024
Phox2b	paired-like homeobox 2b	0.024
Igf1	insulin-like growth factor 1	0.024
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.023
Fcgr3	Fc receptor, IgG, low affinity III	0.023
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.022
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.022
Tbx1	T-box 1	0.022
Tgfbr2	transforming growth factor, beta receptor II	0.022
Kremen2	kringle containing transmembrane protein 2	0.022
Pten	phosphatase and tensin homolog	0.022
Ldlr	low density lipoprotein receptor	0.021
Folr2	folate receptor 2 (fetal)	0.021
Mas1	MAS1 oncogene	0.021
Foxc1	forkhead box C1	0.021
Rgs10	regulator of G-protein signalling 10	0.020
Jag1	jagged 1	0.020
Cnga3	cyclic nucleotide gated channel alpha 3	0.020
Thra	thyroid hormone receptor alpha	0.020
Th	tyrosine hydroxylase	0.020
Fcna	ficolin A	0.020
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Cd68	CD68 antigen	0.019
Lhx9	LIM homeobox protein 9	0.019
Epo	erythropoietin	0.019
Duoxa1	dual oxidase maturation factor 1	0.019
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.018
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.018
Cfp	complement factor properdin	0.018
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.018
Sox2	SRY-box containing gene 2	0.018
Fbn1	fibrillin 1	0.017
Thrb	thyroid hormone receptor beta	0.017
Foxg1	forkhead box G1	0.017
Uncx	UNC homeobox	0.017
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.017
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.017
Jph3	junctophilin 3	0.017
Ebf3	early B-cell factor 3	0.017
Mpl	myeloproliferative leukemia virus oncogene	0.017
Col14a1	collagen, type XIV, alpha 1	0.016
Hoxb1	homeobox B1	0.016
Fosl2	fos-like antigen 2	0.016
Fcgr1	Fc receptor, IgG, high affinity I	0.016
Sox11	SRY-box containing gene 11	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.016
Foxf1a	forkhead box F1a	0.016
Grem1	gremlin 1	0.016
Tshr	thyroid stimulating hormone receptor	0.016
Kl	klotho	0.016
Plac1	placental specific protein 1	0.016
Gli2	GLI-Kruppel family member GLI2	0.016
Gpr50	G-protein-coupled receptor 50	0.016
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.015
Junb	Jun-B oncogene	0.015
Sdc3	syndecan 3	0.015
Neurog3	neurogenin 3	0.015
C3	complement component 3	0.015
Gab2	growth factor receptor bound protein 2-associated protein 2	0.015
Mpeg1	macrophage expressed gene 1	0.015
Tcf21	transcription factor 21	0.015
Hpca	hippocalcin	0.015
Pnliprp2	pancreatic lipase-related protein 2	0.015
Hand1	heart and neural crest derivatives expressed transcript 1	0.014
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.014
H2-DMa	histocompatibility 2, class II, locus DMa	0.014
Col2a1	collagen, type II, alpha 1	0.014
Nkx2-1	NK2 homeobox 1	0.014
Fcgrt	Fc receptor, IgG, alpha chain transporter	0.014
Grid2	glutamate receptor, ionotropic, delta 2	0.014
Mab21l2	mab-21-like 2 (C. elegans)	0.014
Lox	lysyl oxidase	0.014
Ccl6	chemokine (C-C motif) ligand 6	0.014
Nab2	Ngfi-A binding protein 2	0.014
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.014
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.014
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.014
Epha8	Eph receptor A8	0.013
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.013
Ednrb	endothelin receptor type B	0.013
Vstm2b	V-set and transmembrane domain containing 2B	0.013
Nf1	neurofibromatosis 1	0.013
Lyz2	lysozyme 2	0.013
Mpz	myelin protein zero	0.013
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.013
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.012
Tacr2	tachykinin receptor 2	0.012
Efnb2	ephrin B2	0.012
Alx3	aristaless-like homeobox 3	0.012
Cldn5	claudin 5	0.012
Cga	glycoprotein hormones, alpha subunit	0.012
Vax1	ventral anterior homeobox containing gene 1	0.012
Paxip1	PAX interacting (with transcription-activation domain) protein 1	0.012
Pax6	paired box gene 6	0.012
Syt6	synaptotagmin VI	0.012
Hmx1	H6 homeobox 1	0.012
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.012
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.012
Gli3	GLI-Kruppel family member GLI3	0.012
Hoxc11	homeobox C11	0.012
Prph	peripherin	0.011
Pparg	peroxisome proliferator activated receptor gamma	0.011
Wnt4	wingless-related MMTV integration site 4	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Ctnnb1	catenin (cadherin associated protein), beta 1	0.011
R3hdml	R3H domain containing-like	0.011
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.011
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
Mybph	myosin binding protein H	0.011
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.011
Gm711	predicted gene 711	0.011
Syt9	synaptotagmin IX	0.011
Hes3	hairy and enhancer of split 3 (Drosophila)	0.011
Lhx4	LIM homeobox protein 4	0.011
Slc38a8	solute carrier family 38, member 8	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.011
Neurog2	neurogenin 2	0.011
Nrk	Nik related kinase	0.011
Dlx5	distal-less homeobox 5	0.011
Tgfb1	transforming growth factor, beta 1	0.010
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.010
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.010
Pou1f1	POU domain, class 1, transcription factor 1	0.010
Grn	granulin	0.010
Hexa	hexosaminidase A	0.010
Slc12a5	solute carrier family 12, member 5	0.010
Rag2	recombination activating gene 2	0.010
Myoc	myocilin	0.010
Ptgs1	prostaglandin-endoperoxide synthase 1	0.010
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.010