IMP

Process View

Mus musculus

11 genes annotated in mouse

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cartilage morphogenesis

GO:0060536

The process in which the anatomical structures of cartilage are generated and organized.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cartilage morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cartilage morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Msx1	homeobox, msh-like 1	1.000
Shh	sonic hedgehog	1.000
Prrx1	paired related homeobox 1	0.998
Gli3	GLI-Kruppel family member GLI3	0.997
Fgfr2	fibroblast growth factor receptor 2	0.997
Prrx2	paired related homeobox 2	0.990
Hoxa2	homeobox A2	0.986
Tbx1	T-box 1	0.984	Zebrafish
Foxc1	forkhead box C1	0.979
Otx2	orthodenticle homolog 2 (Drosophila)	0.979
Bmp7	bone morphogenetic protein 7	0.979
Hoxd3	homeobox D3	0.944
Hoxa10	homeobox A10	0.940
Gli2	GLI-Kruppel family member GLI2	0.928
Dlx5	distal-less homeobox 5	0.918
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.904
Pbx1	pre B-cell leukemia transcription factor 1	0.903
Rarg	retinoic acid receptor, gamma	0.902
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.898
Bmp4	bone morphogenetic protein 4	0.898
Hoxb3	homeobox B3	0.875
Fgfr1	fibroblast growth factor receptor 1	0.870
Smo	smoothened homolog (Drosophila)	0.870
Pax2	paired box gene 2	0.864
Pax3	paired box gene 3	0.861
Lhx1	LIM homeobox protein 1	0.858
Sox9	SRY-box containing gene 9	0.851	Zebrafish
Hand2	heart and neural crest derivatives expressed transcript 2	0.849
Tcfap2a	transcription factor AP-2, alpha	0.848
En1	engrailed 1	0.841
Eya1	eyes absent 1 homolog (Drosophila)	0.837
Fgf8	fibroblast growth factor 8	0.833
Pax6	paired box gene 6	0.828
Hoxa1	homeobox A1	0.817
Hoxa9	homeobox A9	0.801
Twist2	twist homolog 2 (Drosophila)	0.778	Mouse
Pax8	paired box gene 8	0.777
Hoxb5	homeobox B5	0.764	Mouse
Hoxa5	homeobox A5	0.738
Foxc2	forkhead box C2	0.735
Hoxa11	homeobox A11	0.714
Hoxa3	homeobox A3	0.710
Hand1	heart and neural crest derivatives expressed transcript 1	0.709
Rarb	retinoic acid receptor, beta	0.709
Tgfb2	transforming growth factor, beta 2	0.696
Pax9	paired box gene 9	0.683
Hoxd11	homeobox D11	0.681
Hoxd9	homeobox D9	0.666
Hoxb4	homeobox B4	0.635	Mouse
Gsc	goosecoid homeobox	0.635
Runx2	runt related transcription factor 2	0.627
Hoxd4	homeobox D4	0.608	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.598
Pitx1	paired-like homeodomain transcription factor 1	0.592
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.588
Hoxb6	homeobox B6	0.575	Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.575
Dlx2	distal-less homeobox 2	0.569
Hoxc6	homeobox C6	0.560	Mouse
Snai1	snail homolog 1 (Drosophila)	0.546
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.546
Hoxc8	homeobox C8	0.527	Mouse
Alx3	aristaless-like homeobox 3	0.513
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.508
Gdnf	glial cell line derived neurotrophic factor	0.478
Wnt4	wingless-related MMTV integration site 4	0.445	Mouse
Chrd	chordin	0.418
Hoxb9	homeobox B9	0.396
Hoxc5	homeobox C5	0.393	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.377
Neurod1	neurogenic differentiation 1	0.371	Mouse
Hoxb2	homeobox B2	0.350
T	brachyury	0.335
Hoxd10	homeobox D10	0.324
Hoxa7	homeobox A7	0.316	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.305
Foxd2	forkhead box D2	0.303
Tbx2	T-box 2	0.298
Msx2	homeobox, msh-like 2	0.297	Mouse
Hoxc4	homeobox C4	0.296	Mouse
Tbx3	T-box 3	0.295
Neurog2	neurogenin 2	0.295	Mouse
Hoxa13	homeobox A13	0.290
Foxf1a	forkhead box F1a	0.280
Tcf21	transcription factor 21	0.270
Tbx15	T-box 15	0.262
Hoxc9	homeobox C9	0.256
Neurod4	neurogenic differentiation 4	0.256	Mouse
Sim2	single-minded homolog 2 (Drosophila)	0.249
Ednra	endothelin receptor type A	0.248
Bnc1	basonuclin 1	0.234
Efna2	ephrin A2	0.233
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.218
Bmp2	bone morphogenetic protein 2	0.217
Hoxa4	homeobox A4	0.216	Mouse
Rara	retinoic acid receptor, alpha	0.215
Shox2	short stature homeobox 2	0.211
Wnt11	wingless-related MMTV integration site 11	0.206	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.179
Zfp503	zinc finger protein 503	0.176
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.174
Dlx6	distal-less homeobox 6	0.160
Emid2	EMI domain containing 2	0.160
Wnt6	wingless-related MMTV integration site 6	0.158	Mouse
Fgf10	fibroblast growth factor 10	0.156
Zeb1	zinc finger E-box binding homeobox 1	0.155
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.150
Isl1	ISL1 transcription factor, LIM/homeodomain	0.141
Nhlh1	nescient helix loop helix 1	0.139	Mouse
Lef1	lymphoid enhancer binding factor 1	0.134
Neurog1	neurogenin 1	0.133	Mouse
Hdac4	histone deacetylase 4	0.127
Hoxb7	homeobox B7	0.124	Mouse
Arx	aristaless related homeobox	0.124
Hoxd8	homeobox D8	0.120	Mouse
Lhx9	LIM homeobox protein 9	0.118
Foxg1	forkhead box G1	0.117
Uncx	UNC homeobox	0.111
Col22a1	collagen, type XXII, alpha 1	0.109
Wnt3a	wingless-related MMTV integration site 3A	0.108	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.108
Myog	myogenin	0.103
Sox7	SRY-box containing gene 7	0.101
Tal2	T-cell acute lymphocytic leukemia 2	0.099	Mouse
Hoxd1	homeobox D1	0.098
Nog	noggin	0.097
Hoxb1	homeobox B1	0.097
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.096
Hoxb8	homeobox B8	0.095	Mouse
Lhx3	LIM homeobox protein 3	0.091
Mef2c	myocyte enhancer factor 2C	0.091
Kiss1	KiSS-1 metastasis-suppressor	0.090
Gas1	growth arrest specific 1	0.089
Foxd1	forkhead box D1	0.086
Fgf15	fibroblast growth factor 15	0.079
Lmx1b	LIM homeobox transcription factor 1 beta	0.077
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.077
Gbx2	gastrulation brain homeobox 2	0.076
Foxf2	forkhead box F2	0.076
Hoxd13	homeobox D13	0.074
Foxb1	forkhead box B1	0.070
Foxd3	forkhead box D3	0.070
Fgfr3	fibroblast growth factor receptor 3	0.069
Emx1	empty spiracles homolog 1 (Drosophila)	0.069
Grem1	gremlin 1	0.068
Gpc3	glypican 3	0.067
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.065
Ntf3	neurotrophin 3	0.064
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.062
Foxa2	forkhead box A2	0.061
Col13a1	collagen, type XIII, alpha 1	0.061
Myod1	myogenic differentiation 1	0.060
Pitx3	paired-like homeodomain transcription factor 3	0.058
Mecom	MDS1 and EVI1 complex locus	0.057
Twist1	twist homolog 1 (Drosophila)	0.056	Mouse
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.055
Otx1	orthodenticle homolog 1 (Drosophila)	0.054
Pou3f2	POU domain, class 3, transcription factor 2	0.054
Wnt5b	wingless-related MMTV integration site 5B	0.049	Mouse
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.049
Myf5	myogenic factor 5	0.049
Ptk7	PTK7 protein tyrosine kinase 7	0.048
Amhr2	anti-Mullerian hormone type 2 receptor	0.046
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.046
Mn1	meningioma 1	0.045
Fzd8	frizzled homolog 8 (Drosophila)	0.044
Adra2a	adrenergic receptor, alpha 2a	0.043
Sox11	SRY-box containing gene 11	0.043
Dlk1	delta-like 1 homolog (Drosophila)	0.042
Wt1	Wilms tumor 1 homolog	0.042
Agtr2	angiotensin II receptor, type 2	0.042
Dlx1	distal-less homeobox 1	0.042
Gdf11	growth differentiation factor 11	0.042
Nkx3-2	NK3 homeobox 2	0.042
Bmp5	bone morphogenetic protein 5	0.041
Tal1	T-cell acute lymphocytic leukemia 1	0.040	Mouse
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.040
Lrp5	low density lipoprotein receptor-related protein 5	0.040	Mouse
Meox2	mesenchyme homeobox 2	0.039
Ntn3	netrin 3	0.039
Lhx5	LIM homeobox protein 5	0.038
Hif3a	hypoxia inducible factor 3, alpha subunit	0.038
Edn3	endothelin 3	0.038
Neurog3	neurogenin 3	0.038	Mouse
Meis1	Meis homeobox 1	0.037
Robo3	roundabout homolog 3 (Drosophila)	0.037
Col11a1	collagen, type XI, alpha 1	0.036
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.035
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.034
Tnni2	troponin I, skeletal, fast 2	0.034
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.034
Alx4	aristaless-like homeobox 4	0.034
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.033
Fgf9	fibroblast growth factor 9	0.033
Tead3	TEA domain family member 3	0.032
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.031
Rem1	rad and gem related GTP binding protein 1	0.030
Col2a1	collagen, type II, alpha 1	0.030
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.030
Mpz	myelin protein zero	0.030
Sim1	single-minded homolog 1 (Drosophila)	0.030
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.029
Fgf2	fibroblast growth factor 2	0.029
Gpr50	G-protein-coupled receptor 50	0.029
Dab1	disabled homolog 1 (Drosophila)	0.029
Irx1	Iroquois related homeobox 1 (Drosophila)	0.028
Smad6	MAD homolog 6 (Drosophila)	0.028
Fgf4	fibroblast growth factor 4	0.028
Zfp185	zinc finger protein 185	0.027
Wnt10b	wingless related MMTV integration site 10b	0.027	Mouse
Aplnr	apelin receptor	0.027
Sox2	SRY-box containing gene 2	0.027
Kl	klotho	0.027
Lhx6	LIM homeobox protein 6	0.026
Gli1	GLI-Kruppel family member GLI1	0.026
Fzd10	frizzled homolog 10 (Drosophila)	0.026
Gnrhr	gonadotropin releasing hormone receptor	0.026
Fgf3	fibroblast growth factor 3	0.025
Tbr1	T-box brain gene 1	0.025
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.025
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.024
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.024
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.024
Gata4	GATA binding protein 4	0.024
Stc2	stanniocalcin 2	0.024
Fzd2	frizzled homolog 2 (Drosophila)	0.024
Tcf15	transcription factor 15	0.023	Mouse
Sox1	SRY-box containing gene 1	0.023
Il9r	interleukin 9 receptor	0.023
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.023
Fzd1	frizzled homolog 1 (Drosophila)	0.023
Wnt10a	wingless related MMTV integration site 10a	0.023
Evx2	even skipped homeotic gene 2 homolog	0.023
Gata2	GATA binding protein 2	0.022
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.022
Acan	aggrecan	0.022
Hmx3	H6 homeobox 3	0.022
Pou3f1	POU domain, class 3, transcription factor 1	0.022
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.022
Pou4f2	POU domain, class 4, transcription factor 2	0.022
Notch4	Notch gene homolog 4 (Drosophila)	0.022
Gata1	GATA binding protein 1	0.022
Ihh	Indian hedgehog	0.022
Bmper	BMP-binding endothelial regulator	0.021
Prx	periaxin	0.021
Pou3f4	POU domain, class 3, transcription factor 4	0.021
Fgf18	fibroblast growth factor 18	0.021
Sall3	sal-like 3 (Drosophila)	0.021
Upk3b	uroplakin 3B	0.021
Trp63	transformation related protein 63	0.021
Meis2	Meis homeobox 2	0.020
Pax1	paired box gene 1	0.020
Onecut1	one cut domain, family member 1	0.020
Cldn6	claudin 6	0.020
Col4a4	collagen, type IV, alpha 4	0.019
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.019
Pkdcc	protein kinase domain containing, cytoplasmic	0.019
Zfp771	zinc finger protein 771	0.019
Pdx1	pancreatic and duodenal homeobox 1	0.019
Wnt2b	wingless related MMTV integration site 2b	0.018	Mouse
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.018
Tnnt3	troponin T3, skeletal, fast	0.018
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.018
Tgfa	transforming growth factor alpha	0.018
Tgfbr2	transforming growth factor, beta receptor II	0.018
Plac1	placental specific protein 1	0.018
C1qtnf3	C1q and tumor necrosis factor related protein 3	0.018
Cer1	cerberus 1 homolog (Xenopus laevis)	0.017
Ptgfr	prostaglandin F receptor	0.017
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.017
Efna4	ephrin A4	0.017
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.017
Vstm2b	V-set and transmembrane domain containing 2B	0.017
Amh	anti-Mullerian hormone	0.017
Des	desmin	0.017
Ctnnb1	catenin (cadherin associated protein), beta 1	0.017
Pthlh	parathyroid hormone-like peptide	0.017
Cldn8	claudin 8	0.017
Lbx2	ladybird homeobox homolog 2 (Drosophila)	0.016
Foxi1	forkhead box I1	0.016
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.016
Zfp703	zinc finger protein 703	0.016
Padi3	peptidyl arginine deiminase, type III	0.016
Sp8	trans-acting transcription factor 8	0.016
Eda	ectodysplasin-A	0.016
Mab21l2	mab-21-like 2 (C. elegans)	0.016
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.015
Acvr1	activin A receptor, type 1	0.015
Efs	embryonal Fyn-associated substrate	0.015
Hmx1	H6 homeobox 1	0.015
Sox3	SRY-box containing gene 3	0.015
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.015
Glra1	glycine receptor, alpha 1 subunit	0.015
Hes1	hairy and enhancer of split 1 (Drosophila)	0.015
Tcf4	transcription factor 4	0.014
Barhl1	BarH-like 1 (Drosophila)	0.014
Efnb1	ephrin B1	0.014
Ebf3	early B-cell factor 3	0.014
Smoc2	SPARC related modular calcium binding 2	0.014
Tcfap2b	transcription factor AP-2 beta	0.014
Cdh3	cadherin 3	0.014
Col4a3	collagen, type IV, alpha 3	0.014
Ltbp1	latent transforming growth factor beta binding protein 1	0.014
Mdfi	MyoD family inhibitor	0.014
Gja3	gap junction protein, alpha 3	0.014
Nkd1	naked cuticle 1 homolog (Drosophila)	0.014
Hoxd12	homeobox D12	0.014
Btbd17	BTB (POZ) domain containing 17	0.014
Efna5	ephrin A5	0.014
Nobox	NOBOX oogenesis homeobox	0.014
Magel2	melanoma antigen, family L, 2	0.014
Crb2	crumbs homolog 2 (Drosophila)	0.014
Nes	nestin	0.014
Sh3pxd2a	SH3 and PX domains 2A	0.014
Fzd6	frizzled homolog 6 (Drosophila)	0.014
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Ar	androgen receptor	0.013
Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.013
Sox13	SRY-box containing gene 13	0.013
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.013
Dbx1	developing brain homeobox 1	0.013
Hmga2	high mobility group AT-hook 2	0.013
Mnx1	motor neuron and pancreas homeobox 1	0.013
Mrc2	mannose receptor, C type 2	0.013
Wnt1	wingless-related MMTV integration site 1	0.013	Mouse
Emid1	EMI domain containing 1	0.013
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.012
Miox	myo-inositol oxygenase	0.012
Tcfap2c	transcription factor AP-2, gamma	0.012
Pax7	paired box gene 7	0.012
Nkx6-1	NK6 homeobox 1	0.012
Fev	FEV (ETS oncogene family)	0.012
Npc1	Niemann Pick type C1	0.012
Gsx2	GS homeobox 2	0.012
Hes5	hairy and enhancer of split 5 (Drosophila)	0.012
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.012
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.012
Isl2	insulin related protein 2 (islet 2)	0.012
Wnt9a	wingless-type MMTV integration site 9A	0.012	Mouse
Greb1	gene regulated by estrogen in breast cancer protein	0.012
Mapk12	mitogen-activated protein kinase 12	0.012
Tbx6	T-box 6	0.012
Mrvi1	MRV integration site 1	0.012
Tlx3	T-cell leukemia, homeobox 3	0.012
Matn3	matrilin 3	0.012	Mouse
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.012
Nrtn	neurturin	0.011
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.011
Rax	retina and anterior neural fold homeobox	0.011
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.011
Trim62	tripartite motif-containing 62	0.011
Irx4	Iroquois related homeobox 4 (Drosophila)	0.011
Myoz1	myozenin 1	0.011
Slc25a29	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29	0.011
Matn1	matrilin 1, cartilage matrix protein	0.011
Sp5	trans-acting transcription factor 5	0.011
Adra2b	adrenergic receptor, alpha 2b	0.011
Nkx2-1	NK2 homeobox 1	0.011
Krtap3-3	keratin associated protein 3-3	0.011
Foxe3	forkhead box E3	0.011
Crabp2	cellular retinoic acid binding protein II	0.011
Capn6	calpain 6	0.011
Fhl3	four and a half LIM domains 3	0.011
Alx1	ALX homeobox 1	0.011
Srpk3	serine/arginine-rich protein specific kinase 3	0.011
Has2	hyaluronan synthase 2	0.011
Fgf5	fibroblast growth factor 5	0.011
Ptch1	patched homolog 1	0.011
Vax1	ventral anterior homeobox containing gene 1	0.011
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.011
Aif1l	allograft inflammatory factor 1-like	0.010
Snai2	snail homolog 2 (Drosophila)	0.010
Pcdh12	protocadherin 12	0.010
She	src homology 2 domain-containing transforming protein E	0.010
Osr1	odd-skipped related 1 (Drosophila)	0.010
Ptf1a	pancreas specific transcription factor, 1a	0.010	Mouse
Foxd4	forkhead box D4	0.010
Itga8	integrin alpha 8	0.010
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.010
Sox21	SRY-box containing gene 21	0.010
Cdx1	caudal type homeobox 1	0.010
Dhh	desert hedgehog	0.010