IMP
Process View
g0 to g1 transition
The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.
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Click on a gene's description to view its network relationships with genes known to be involved in "g0 to g1 transition"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 0.916 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.803 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.751 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.665 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.660 | ||
| Pax3 | paired box gene 3 | 0.658 | ||
| Shh | sonic hedgehog | 0.637 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.530 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.484 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.393 | ||
| Prrx1 | paired related homeobox 1 | 0.388 | ||
| Nf1 | neurofibromatosis 1 | 0.345 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.298 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.284 | ||
| Alx4 | aristaless-like homeobox 4 | 0.268 | ||
| Meox2 | mesenchyme homeobox 2 | 0.246 | ||
| Fgf10 | fibroblast growth factor 10 | 0.243 | ||
| Pthlh | parathyroid hormone-like peptide | 0.217 | ||
| Sox11 | SRY-box containing gene 11 | 0.186 | Mouse | |
| Sox4 | SRY-box containing gene 4 | 0.182 | Mouse | |
| Bmp4 | bone morphogenetic protein 4 | 0.178 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.178 | ||
| Sox9 | SRY-box containing gene 9 | 0.173 | Mouse | |
| Ret | ret proto-oncogene | 0.172 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.159 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.151 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.148 | ||
| Foxc1 | forkhead box C1 | 0.137 | ||
| Thbs1 | thrombospondin 1 | 0.130 | ||
| Gata4 | GATA binding protein 4 | 0.123 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.113 | ||
| Efnb2 | ephrin B2 | 0.110 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.110 | ||
| Cldn5 | claudin 5 | 0.095 | ||
| Sox2 | SRY-box containing gene 2 | 0.089 | Mouse | |
| Atoh7 | atonal homolog 7 (Drosophila) | 0.087 | ||
| Pax6 | paired box gene 6 | 0.085 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.084 | ||
| Kit | kit oncogene | 0.084 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.083 | ||
| Rb1 | retinoblastoma 1 | 0.077 | ||
| Josd2 | Josephin domain containing 2 | 0.071 | ||
| She | src homology 2 domain-containing transforming protein E | 0.070 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.068 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.066 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.065 | ||
| Fgf4 | fibroblast growth factor 4 | 0.064 | ||
| Rarb | retinoic acid receptor, beta | 0.061 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.058 | ||
| Xpo4 | exportin 4 | 0.057 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.055 | ||
| Ikbkap | inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein | 0.055 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.055 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.053 | ||
| Tcf15 | transcription factor 15 | 0.053 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.051 | ||
| Fgf8 | fibroblast growth factor 8 | 0.051 | ||
| Kdr | kinase insert domain protein receptor | 0.049 | ||
| Sfn | stratifin | 0.049 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.049 | ||
| Rara | retinoic acid receptor, alpha | 0.046 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.046 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.045 | ||
| Ednra | endothelin receptor type A | 0.045 | ||
| Foxi3 | forkhead box I3 | 0.044 | ||
| Max | Max protein | 0.041 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.040 | ||
| Sox17 | SRY-box containing gene 17 | 0.040 | Mouse | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.038 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.037 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.036 | ||
| Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.034 | ||
| Nanog | Nanog homeobox | 0.034 | ||
| Iqgap3 | IQ motif containing GTPase activating protein 3 | 0.033 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.033 | ||
| Cdk9 | cyclin-dependent kinase 9 (CDC2-related kinase) | 0.032 | ||
| Alx3 | aristaless-like homeobox 3 | 0.032 | ||
| Insm1 | insulinoma-associated 1 | 0.031 | ||
| Ntf3 | neurotrophin 3 | 0.031 | ||
| Esam | endothelial cell-specific adhesion molecule | 0.031 | ||
| Fxc1 | fractured callus expressed transcript 1 | 0.031 | ||
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.031 | ||
| Hhex | hematopoietically expressed homeobox | 0.031 | ||
| Acvr1 | activin A receptor, type 1 | 0.030 | ||
| Tbx2 | T-box 2 | 0.030 | ||
| Brca1 | breast cancer 1 | 0.029 | ||
| Ednrb | endothelin receptor type B | 0.029 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.028 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.027 | ||
| Rasip1 | Ras interacting protein 1 | 0.027 | ||
| Foxd2 | forkhead box D2 | 0.027 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.027 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.026 | ||
| Gm13290 | predicted gene 13290 | 0.026 | ||
| Hrh2 | histamine receptor H2 | 0.026 | ||
| Kitl | kit ligand | 0.026 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.026 | ||
| Msx1 | homeobox, msh-like 1 | 0.026 | ||
| Fgfrl1 | fibroblast growth factor receptor-like 1 | 0.025 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.025 | ||
| Ep400 | E1A binding protein p400 | 0.025 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.025 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.025 | ||
| F3 | coagulation factor III | 0.025 | ||
| Fgf18 | fibroblast growth factor 18 | 0.024 | ||
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.024 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.024 | ||
| Pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.024 | ||
| Alx1 | ALX homeobox 1 | 0.024 | ||
| Tubb2c | tubulin, beta 2C | 0.023 | ||
| Smo | smoothened homolog (Drosophila) | 0.023 | ||
| Cdh5 | cadherin 5 | 0.023 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.023 | ||
| Pou3f1 | POU domain, class 3, transcription factor 1 | 0.023 | ||
| Crebbp | CREB binding protein | 0.022 | ||
| Hoxa5 | homeobox A5 | 0.022 | ||
| Esrrb | estrogen related receptor, beta | 0.021 | ||
| Timp3 | tissue inhibitor of metalloproteinase 3 | 0.021 | ||
| Dhh | desert hedgehog | 0.021 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.021 | ||
| Agrp | agouti related protein | 0.021 | ||
| Fgd5 | FYVE, RhoGEF and PH domain containing 5 | 0.021 | ||
| Tinagl1 | tubulointerstitial nephritis antigen-like 1 | 0.021 | ||
| Tcfap2c | transcription factor AP-2, gamma | 0.021 | ||
| Hoxa3 | homeobox A3 | 0.021 | ||
| Tceb2 | transcription elongation factor B (SIII), polypeptide 2 | 0.020 | ||
| Skil | SKI-like | 0.020 | ||
| Gja4 | gap junction protein, alpha 4 | 0.020 | ||
| Vegfa | vascular endothelial growth factor A | 0.020 | ||
| Ptch1 | patched homolog 1 | 0.020 | ||
| Eng | endoglin | 0.020 | ||
| Cyr61 | cysteine rich protein 61 | 0.020 | ||
| Apc | adenomatosis polyposis coli | 0.019 | ||
| Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.019 | ||
| Rarg | retinoic acid receptor, gamma | 0.019 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.019 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.019 | ||
| Tbx15 | T-box 15 | 0.019 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.019 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.018 | ||
| Mitf | microphthalmia-associated transcription factor | 0.018 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.018 | ||
| Mea1 | male enhanced antigen 1 | 0.018 | ||
| Bmper | BMP-binding endothelial regulator | 0.018 | ||
| Elof1 | elongation factor 1 homolog (ELF1, S. cerevisiae) | 0.017 | ||
| Id1 | inhibitor of DNA binding 1 | 0.017 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.017 | ||
| Shank3 | SH3/ankyrin domain gene 3 | 0.017 | ||
| Jup | junction plakoglobin | 0.017 | ||
| Sssca1 | Sjogren's syndrome/scleroderma autoantigen 1 homolog (human) | 0.017 | ||
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 0.017 | ||
| Olig2 | oligodendrocyte transcription factor 2 | 0.017 | ||
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.017 | ||
| Aplnr | apelin receptor | 0.017 | ||
| Dctn3 | dynactin 3 | 0.017 | ||
| Krt17 | keratin 17 | 0.016 | ||
| Lsmd1 | LSM domain containing 1 | 0.016 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.016 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.016 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.016 | ||
| Tshz3 | teashirt zinc finger family member 3 | 0.016 | ||
| Tead4 | TEA domain family member 4 | 0.016 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.016 | ||
| Tert | telomerase reverse transcriptase | 0.016 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.016 | ||
| Trp73 | transformation related protein 73 | 0.015 | ||
| Edn1 | endothelin 1 | 0.015 | ||
| Smn1 | survival motor neuron 1 | 0.015 | ||
| Tnp1 | transition protein 1 | 0.015 | ||
| Trp63 | transformation related protein 63 | 0.015 | ||
| Nkx2-2 | NK2 transcription factor related, locus 2 (Drosophila) | 0.015 | ||
| 2900010M23Rik | RIKEN cDNA 2900010M23 gene | 0.015 | ||
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.015 | ||
| Upk2 | uroplakin 2 | 0.015 | ||
| Csnk1e | casein kinase 1, epsilon | 0.015 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.015 | ||
| Apln | apelin | 0.015 | ||
| Gna11 | guanine nucleotide binding protein, alpha 11 | 0.015 | ||
| Lhx3 | LIM homeobox protein 3 | 0.015 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.015 | ||
| Sox3 | SRY-box containing gene 3 | 0.015 | Mouse | |
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.014 | ||
| Foxc2 | forkhead box C2 | 0.014 | ||
| Hipk1 | homeodomain interacting protein kinase 1 | 0.014 | ||
| Nog | noggin | 0.014 | ||
| Ccdc56 | coiled-coil domain containing 56 | 0.014 | ||
| Mcam | melanoma cell adhesion molecule | 0.014 | ||
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.014 | ||
| Dtl | denticleless homolog (Drosophila) | 0.014 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.014 | ||
| Dlx1 | distal-less homeobox 1 | 0.014 | ||
| Nrtn | neurturin | 0.014 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.014 | ||
| Tpi1 | triosephosphate isomerase 1 | 0.014 | ||
| E2f1 | E2F transcription factor 1 | 0.013 | ||
| Tsc1 | tuberous sclerosis 1 | 0.013 | ||
| Slc12a2 | solute carrier family 12, member 2 | 0.013 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.013 | ||
| Hoxa2 | homeobox A2 | 0.013 | ||
| Atp5e | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 0.013 | ||
| Sox18 | SRY-box containing gene 18 | 0.013 | Mouse | |
| Cux1 | cut-like homeobox 1 | 0.013 | ||
| Kank3 | KN motif and ankyrin repeat domains 3 | 0.013 | ||
| Ebf3 | early B-cell factor 3 | 0.013 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.013 | ||
| Tek | endothelial-specific receptor tyrosine kinase | 0.013 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.013 | ||
| Jag2 | jagged 2 | 0.013 | ||
| Grik4 | glutamate receptor, ionotropic, kainate 4 | 0.013 | ||
| Zbtb46 | zinc finger and BTB domain containing 46 | 0.013 | ||
| Arx | aristaless related homeobox | 0.013 | ||
| Foxm1 | forkhead box M1 | 0.012 | ||
| Meox1 | mesenchyme homeobox 1 | 0.012 | ||
| H2-M9 | histocompatibility 2, M region locus 9 | 0.012 | ||
| Errfi1 | ERBB receptor feedback inhibitor 1 | 0.012 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.012 | ||
| Gata6 | GATA binding protein 6 | 0.012 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.012 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.012 | ||
| Ncoa6 | nuclear receptor coactivator 6 | 0.012 | ||
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.012 | ||
| Cdc42ep1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.012 | ||
| Rimklb | ribosomal modification protein rimK-like family member B | 0.012 | ||
| Galr1 | galanin receptor 1 | 0.012 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.012 | ||
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.012 | ||
| Satb2 | special AT-rich sequence binding protein 2 | 0.012 | ||
| Exo1 | exonuclease 1 | 0.012 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.011 | ||
| Dmrtb1 | DMRT-like family B with proline-rich C-terminal, 1 | 0.011 | ||
| Tcof1 | Treacher Collins Franceschetti syndrome 1, homolog | 0.011 | ||
| Sct | secretin | 0.011 | ||
| Ogg1 | 8-oxoguanine DNA-glycosylase 1 | 0.011 | ||
| Icam2 | intercellular adhesion molecule 2 | 0.011 | ||
| Yap1 | yes-associated protein 1 | 0.011 | ||
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.011 | ||
| Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.011 | ||
| Rnf2 | ring finger protein 2 | 0.011 | ||
| Ankrd2 | ankyrin repeat domain 2 (stretch responsive muscle) | 0.011 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.011 | ||
| Pten | phosphatase and tensin homolog | 0.011 | ||
| Emcn | endomucin | 0.011 | ||
| Gja1 | gap junction protein, alpha 1 | 0.011 | ||
| Hapln3 | hyaluronan and proteoglycan link protein 3 | 0.011 | ||
| Nrg1 | neuregulin 1 | 0.011 | ||
| Htr4 | 5 hydroxytryptamine (serotonin) receptor 4 | 0.011 | ||
| Epha4 | Eph receptor A4 | 0.011 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.011 | ||
| Nptx2 | neuronal pentraxin 2 | 0.011 | ||
| Rps6kb1 | ribosomal protein S6 kinase, polypeptide 1 | 0.011 | ||
| Edf1 | endothelial differentiation-related factor 1 | 0.011 | ||
| Timm13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.011 | ||
| Ctgf | connective tissue growth factor | 0.011 | Rat | |
| Limch1 | LIM and calponin homology domains 1 | 0.011 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.011 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.011 | ||
| Mgmt | O-6-methylguanine-DNA methyltransferase | 0.011 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.011 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.011 | ||
| Bax | BCL2-associated X protein | 0.011 | ||
| Tmeff2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | 0.011 | ||
| Trappc2l | trafficking protein particle complex 2-like | 0.011 | ||
| Tubb6 | tubulin, beta 6 | 0.010 | ||
| Tcf7l1 | transcription factor 7-like 1 (T-cell specific, HMG box) | 0.010 | ||
| Wdr43 | WD repeat domain 43 | 0.010 | ||
| Hdac1 | histone deacetylase 1 | 0.010 | ||
| Asna1 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 0.010 | ||
| Gata3 | GATA binding protein 3 | 0.010 | ||
| Fhl3 | four and a half LIM domains 3 | 0.010 | ||
| Pla2g10 | phospholipase A2, group X | 0.010 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.010 | ||
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.010 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.010 | ||
| Timeless | timeless homolog (Drosophila) | 0.010 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.010 | ||
| Wnk2 | WNK lysine deficient protein kinase 2 | 0.010 | ||
| Sncg | synuclein, gamma | 0.010 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.010 | ||
| Jag1 | jagged 1 | 0.010 | ||
| Wwtr1 | WW domain containing transcription regulator 1 | 0.010 |