IMP

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Mus musculus

4 genes annotated in mouse

cholesterol storage

The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol storage"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cholesterol storage" (in gray)

Name	Description	Probability	Func Analog Organism
Apoe	apolipoprotein E	0.997
Cav1	caveolin 1, caveolae protein	0.997
Ghr	growth hormone receptor	0.978
Lepr	leptin receptor	0.975
Ldlr	low density lipoprotein receptor	0.916
Vegfa	vascular endothelial growth factor A	0.862
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.857
Nos3	nitric oxide synthase 3, endothelial cell	0.835
Lep	leptin	0.673
Rxra	retinoid X receptor alpha	0.667
Pnpla2	patatin-like phospholipase domain containing 2	0.640
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.530
Apoa1	apolipoprotein A-I	0.508
Lipe	lipase, hormone sensitive	0.418
Cidec	cell death-inducing DFFA-like effector c	0.392
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.361
Npc1	Niemann Pick type C1	0.331
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.305
Bcl2	B-cell leukemia/lymphoma 2	0.302
Fabp4	fatty acid binding protein 4, adipocyte	0.290
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.244
Pcx	pyruvate carboxylase	0.240
Srf	serum response factor	0.226
Lpin1	lipin 1	0.208
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.208
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.204
Scd1	stearoyl-Coenzyme A desaturase 1	0.193
Esr1	estrogen receptor 1 (alpha)	0.186
Lrp1	low density lipoprotein receptor-related protein 1	0.177
Plin1	perilipin 1	0.174
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.155
Aldob	aldolase B, fructose-bisphosphate	0.144
Lpl	lipoprotein lipase	0.133
Adipoq	adiponectin, C1Q and collagen domain containing	0.121
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.119
Adrb3	adrenergic receptor, beta 3	0.112
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.111
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.111
Tlr4	toll-like receptor 4	0.106
Ehd4	EH-domain containing 4	0.104	Mouse
Gnrh1	gonadotropin releasing hormone 1	0.098
Fabp1	fatty acid binding protein 1, liver	0.095
Lmna	lamin A	0.094
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.092
Cd36	CD36 antigen	0.089
Ehd3	EH-domain containing 3	0.088	Mouse
Gata6	GATA binding protein 6	0.088
Lipa	lysosomal acid lipase A	0.084
Myo1c	myosin IC	0.077
Dhcr7	7-dehydrocholesterol reductase	0.075
Clock	circadian locomotor output cycles kaput	0.072
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.070
Abhd5	abhydrolase domain containing 5	0.069
F10	coagulation factor X	0.058
Fzd4	frizzled homolog 4 (Drosophila)	0.057
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.056
Plin4	perilipin 4	0.054
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.054
Crtc3	CREB regulated transcription coactivator 3	0.054
Notch2	Notch gene homolog 2 (Drosophila)	0.054
Cd151	CD151 antigen	0.054
Pparg	peroxisome proliferator activated receptor gamma	0.052	Human
Flii	flightless I homolog (Drosophila)	0.052
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.048
Mgll	monoglyceride lipase	0.047
Ilk	integrin linked kinase	0.046
Cd5l	CD5 antigen-like	0.045
Actn4	actinin alpha 4	0.044
Tlr2	toll-like receptor 2	0.044
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.043
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.041
Ephx2	epoxide hydrolase 2, cytoplasmic	0.040
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.040
C5ar1	complement component 5a receptor 1	0.040
Gjb2	gap junction protein, beta 2	0.040
Ar	androgen receptor	0.039
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.038
Egfr	epidermal growth factor receptor	0.037
Apoc1	apolipoprotein C-I	0.037
Il6st	interleukin 6 signal transducer	0.037
Dhcr24	24-dehydrocholesterol reductase	0.036
Por	P450 (cytochrome) oxidoreductase	0.035
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.035
Pten	phosphatase and tensin homolog	0.035
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.035
Agtr1a	angiotensin II receptor, type 1a	0.034
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.034
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.034
Sqstm1	sequestosome 1	0.033
Adrb1	adrenergic receptor, beta 1	0.033
Igf1	insulin-like growth factor 1	0.032
Vnn3	vanin 3	0.031
Adrb2	adrenergic receptor, beta 2	0.031
F7	coagulation factor VII	0.031
Gpr182	G protein-coupled receptor 182	0.030
Hmg20b	high mobility group 20 B	0.030
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.030
Irs2	insulin receptor substrate 2	0.030
Fcna	ficolin A	0.030
Mpv17	MpV17 mitochondrial inner membrane protein	0.029
Lrp10	low-density lipoprotein receptor-related protein 10	0.029
Ncoa3	nuclear receptor coactivator 3	0.029
Mapkapk2	MAP kinase-activated protein kinase 2	0.029
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.028
Ces1d	carboxylesterase 1D	0.028
Stat3	signal transducer and activator of transcription 3	0.028
Ncln	nicalin homolog (zebrafish)	0.027
Cox8b	cytochrome c oxidase, subunit VIIIb	0.027
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.027
Ces1g	carboxylesterase 1G	0.027
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.027
Orm1	orosomucoid 1	0.026
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.026
Thra	thyroid hormone receptor alpha	0.026
Ncor2	nuclear receptor co-repressor 2	0.026
Akt1	thymoma viral proto-oncogene 1	0.026
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.026
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.026
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.025
Myof	myoferlin	0.025
Angptl4	angiopoietin-like 4	0.025
Bag6	BCL2-associated athanogene 6	0.024
Apof	apolipoprotein F	0.024
Insr	insulin receptor	0.024
Fam108a	family with sequence similarity 108, member A	0.024
Pilra	paired immunoglobin-like type 2 receptor alpha	0.023
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.023
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.023
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.023
Slc12a6	solute carrier family 12, member 6	0.023
Hamp	hepcidin antimicrobial peptide	0.023
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.023
Hal	histidine ammonia lyase	0.022
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.022
Nadk	NAD kinase	0.022
Aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.022
Foxa3	forkhead box A3	0.022
Ltbr	lymphotoxin B receptor	0.022
Necap2	NECAP endocytosis associated 2	0.022
Plvap	plasmalemma vesicle associated protein	0.021
Hpx	hemopexin	0.021
Fpr1	formyl peptide receptor 1	0.021
Gba	glucosidase, beta, acid	0.021
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.021
Dgat2	diacylglycerol O-acyltransferase 2	0.021
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.021
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.020
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.020
Pon1	paraoxonase 1	0.020
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.020
Car3	carbonic anhydrase 3	0.020
Galm	galactose mutarotase	0.019
C3	complement component 3	0.019
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.019
Ece1	endothelin converting enzyme 1	0.019
Otc	ornithine transcarbamylase	0.019
Pdzk1	PDZ domain containing 1	0.019
Acsl1	acyl-CoA synthetase long-chain family member 1	0.019
Hgfac	hepatocyte growth factor activator	0.019
Gns	glucosamine (N-acetyl)-6-sulfatase	0.019
Apoc2	apolipoprotein C-II	0.019
Acy3	aspartoacylase (aminoacylase) 3	0.019
Tgfb1	transforming growth factor, beta 1	0.019
Scd2	stearoyl-Coenzyme A desaturase 2	0.019
Ahsg	alpha-2-HS-glycoprotein	0.019
Fads2	fatty acid desaturase 2	0.019
Sqle	squalene epoxidase	0.018
Vhl	von Hippel-Lindau tumor suppressor	0.018
Esrra	estrogen related receptor, alpha	0.018
Crat	carnitine acetyltransferase	0.018
Sardh	sarcosine dehydrogenase	0.018
Sh3glb2	SH3-domain GRB2-like endophilin B2	0.018
Prkci	protein kinase C, iota	0.018
Ubl7	ubiquitin-like 7 (bone marrow stromal cell-derived)	0.017
Sult1b1	sulfotransferase family 1B, member 1	0.017
Apoa2	apolipoprotein A-II	0.017
Plbd2	phospholipase B domain containing 2	0.017
Ninj1	ninjurin 1	0.017
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.017
Ocel1	occludin/ELL domain containing 1	0.017
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.017
AI464131	expressed sequence AI464131	0.017
Adap2	ArfGAP with dual PH domains 2	0.016
Tmem37	transmembrane protein 37	0.016
Fmo1	flavin containing monooxygenase 1	0.016
Sorbs1	sorbin and SH3 domain containing 1	0.016
Nnmt	nicotinamide N-methyltransferase	0.016
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.016
Dda1	DET1 and DDB1 associated 1	0.016
Rdh16	retinol dehydrogenase 16	0.016
Frmd8	FERM domain containing 8	0.016
Apoa4	apolipoprotein A-IV	0.016
Klf15	Kruppel-like factor 15	0.016
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.016
Ptrf	polymerase I and transcript release factor	0.016
C8g	complement component 8, gamma polypeptide	0.016
Zfpl1	zinc finger like protein 1	0.016
Ptprb	protein tyrosine phosphatase, receptor type, B	0.016
Pex11a	peroxisomal biogenesis factor 11 alpha	0.015
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.015
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.015
Cfb	complement factor B	0.015
Tmem115	transmembrane protein 115	0.015
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.015
Asgr2	asialoglycoprotein receptor 2	0.015
Psen1	presenilin 1	0.015
Palmd	palmdelphin	0.015
Pnkp	polynucleotide kinase 3'- phosphatase	0.015
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.015
Yipf3	Yip1 domain family, member 3	0.015
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.015
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.015
Il1r1	interleukin 1 receptor, type I	0.015
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.015
Adat3	adenosine deaminase, tRNA-specific 3, TAD2 homolog (S. cerevisiae)	0.015
Mertk	c-mer proto-oncogene tyrosine kinase	0.014
Abhd12	abhydrolase domain containing 12	0.014
Bst1	bone marrow stromal cell antigen 1	0.014
Hnf4a	hepatic nuclear factor 4, alpha	0.014
Wdr1	WD repeat domain 1	0.014
Cnpy3	canopy 3 homolog (zebrafish)	0.014
Mrap	melanocortin 2 receptor accessory protein	0.014
Pecam1	platelet/endothelial cell adhesion molecule 1	0.014
Lifr	leukemia inhibitory factor receptor	0.014
Saa3	serum amyloid A 3	0.014
Hgd	homogentisate 1, 2-dioxygenase	0.014
Acp5	acid phosphatase 5, tartrate resistant	0.014
Steap4	STEAP family member 4	0.014
Cfh	complement component factor h	0.014
Adig	adipogenin	0.014
Tspan4	tetraspanin 4	0.013
Inmt	indolethylamine N-methyltransferase	0.013
Fgf1	fibroblast growth factor 1	0.013
Csf1	colony stimulating factor 1 (macrophage)	0.013
Fkbp8	FK506 binding protein 8	0.013
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.013
Rxrg	retinoid X receptor gamma	0.013
Rab1b	RAB1B, member RAS oncogene family	0.013
Fez2	fasciculation and elongation protein zeta 2 (zygin II)	0.013
Ppp6r1	protein phosphatase 6, regulatory subunit 1	0.013
Lrp5	low density lipoprotein receptor-related protein 5	0.013
Aadac	arylacetamide deacetylase (esterase)	0.013
Adh1	alcohol dehydrogenase 1 (class I)	0.013
Cry2	cryptochrome 2 (photolyase-like)	0.013
Fbxw8	F-box and WD-40 domain protein 8	0.013
Rab17	RAB17, member RAS oncogene family	0.013
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.013
Iyd	iodotyrosine deiodinase	0.013
Lama4	laminin, alpha 4	0.013
Sbf1	SET binding factor 1	0.013
Fam73b	family with sequence similarity 73, member B	0.013
Mlycd	malonyl-CoA decarboxylase	0.013
Azgp1	alpha-2-glycoprotein 1, zinc	0.013
Kdr	kinase insert domain protein receptor	0.013
Vps37b	vacuolar protein sorting 37B (yeast)	0.013
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.013
Fam167b	family with sequence similarity 167, member B	0.013
Tpra1	transmembrane protein, adipocyte asscociated 1	0.013
Hk3	hexokinase 3	0.013
Bche	butyrylcholinesterase	0.013
Csrp1	cysteine and glycine-rich protein 1	0.013
G0s2	G0/G1 switch gene 2	0.013
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.013
Atg7	autophagy-related 7 (yeast)	0.012
Fabp2	fatty acid binding protein 2, intestinal	0.012
Tspan12	tetraspanin 12	0.012
Man2a1	mannosidase 2, alpha 1	0.012
F2	coagulation factor II	0.012
Ccl2	chemokine (C-C motif) ligand 2	0.012
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.012
Mmp12	matrix metallopeptidase 12	0.012
Sh3tc1	SH3 domain and tetratricopeptide repeats 1	0.012
Car5b	carbonic anhydrase 5b, mitochondrial	0.012
Rab4b	RAB4B, member RAS oncogene family	0.012
Clec4e	C-type lectin domain family 4, member e	0.012
Thrb	thyroid hormone receptor beta	0.012
Capn2	calpain 2	0.012
Wbp2	WW domain binding protein 2	0.012
Angptl3	angiopoietin-like 3	0.012
Pex14	peroxisomal biogenesis factor 14	0.012
Flt1	FMS-like tyrosine kinase 1	0.012
S1pr1	sphingosine-1-phosphate receptor 1	0.012
Cyp51	cytochrome P450, family 51	0.012
Tsc22d3	TSC22 domain family, member 3	0.012
Alas1	aminolevulinic acid synthase 1	0.012
Pdgfb	platelet derived growth factor, B polypeptide	0.012
Adipor2	adiponectin receptor 2	0.012
Gpr146	G protein-coupled receptor 146	0.012
Dbnl	drebrin-like	0.012
Eng	endoglin	0.012
Tpst2	protein-tyrosine sulfotransferase 2	0.012
Dpyd	dihydropyrimidine dehydrogenase	0.012
Vps72	vacuolar protein sorting 72 (yeast)	0.012
F8	coagulation factor VIII	0.012
Gc	group specific component	0.012
Ces2e	carboxylesterase 2E	0.012
Tgfbr2	transforming growth factor, beta receptor II	0.012
Mmp19	matrix metallopeptidase 19	0.012
Ces2g	carboxylesterase 2G	0.012
Mif4gd	MIF4G domain containing	0.011
Triobp	TRIO and F-actin binding protein	0.011
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.011
Car5a	carbonic anhydrase 5a, mitochondrial	0.011
Nrg4	neuregulin 4	0.011
Gnmt	glycine N-methyltransferase	0.011
Csnk1g2	casein kinase 1, gamma 2	0.011
Ambp	alpha 1 microglobulin/bikunin	0.011
Pygl	liver glycogen phosphorylase	0.011
Gsta3	glutathione S-transferase, alpha 3	0.011
Cry1	cryptochrome 1 (photolyase-like)	0.011
Clec4a2	C-type lectin domain family 4, member a2	0.011
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.011
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.011
Plod1	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	0.011
Lass2	LAG1 homolog, ceramide synthase 2	0.011
Kng1	kininogen 1	0.011
Mmd	monocyte to macrophage differentiation-associated	0.011
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.011	Human Mouse
Ppap2a	phosphatidic acid phosphatase type 2A	0.011
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.011
Vasp	vasodilator-stimulated phosphoprotein	0.011
Prnp	prion protein	0.011
Mvd	mevalonate (diphospho) decarboxylase	0.011
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.011
Stom	stomatin	0.011
Alb	albumin	0.011
Mat1a	methionine adenosyltransferase I, alpha	0.011
Aco1	aconitase 1	0.011
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.011
Gipc1	GIPC PDZ domain containing family, member 1	0.011
Ehbp1l1	EH domain binding protein 1-like 1	0.011
Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.011
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.011
Sdpr	serum deprivation response	0.011
Plbd1	phospholipase B domain containing 1	0.011
Khk	ketohexokinase	0.011
Soat2	sterol O-acyltransferase 2	0.011
Tcn2	transcobalamin 2	0.011
Stard4	StAR-related lipid transfer (START) domain containing 4	0.011
Cfi	complement component factor i	0.011
Fgg	fibrinogen gamma chain	0.011
Esam	endothelial cell-specific adhesion molecule	0.010
Ctsd	cathepsin D	0.010
Slc26a4	solute carrier family 26, member 4	0.010
Rab5c	RAB5C, member RAS oncogene family	0.010
Atg9a	autophagy-related 9A (yeast)	0.010
Vtn	vitronectin	0.010
Traf7	TNF receptor-associated factor 7	0.010
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.010
Tbc1d17	TBC1 domain family, member 17	0.010
F13b	coagulation factor XIII, beta subunit	0.010
C9	complement component 9	0.010
Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.010
Abcd2	ATP-binding cassette, sub-family D (ALD), member 2	0.010
Cant1	calcium activated nucleotidase 1	0.010
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.010
Ptgs2	prostaglandin-endoperoxide synthase 2	0.010
Scyl1	SCY1-like 1 (S. cerevisiae)	0.010
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)	0.010
Aacs	acetoacetyl-CoA synthetase	0.010
Cdc42bpb	CDC42 binding protein kinase beta	0.010
Dgat1	diacylglycerol O-acyltransferase 1	0.010
Tfip11	tuftelin interacting protein 11	0.010
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.010
Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	0.010
Gatm	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.010
Vav2	vav 2 oncogene	0.010
Rptor	regulatory associated protein of MTOR, complex 1	0.010
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.010
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.010
4930471M23Rik	RIKEN cDNA 4930471M23 gene	0.010
Dysf	dysferlin	0.010
Dusp1	dual specificity phosphatase 1	0.010
Mttp	microsomal triglyceride transfer protein	0.010
Adra1b	adrenergic receptor, alpha 1b	0.010