IMP

Process View

Rattus norvegicus

4 genes annotated in rat

Multi-species View

positive regulation of blood coagulation

GO:0030194

Any process that activates or increases the frequency, rate or extent of blood coagulation.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of blood coagulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of blood coagulation" (in gray)

Name	Description	Probability	Func Analog Organism
Pzp	pregnancy-zone protein	0.759
C1s	complement component 1, s subcomponent	0.521
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.484
Ifitm3	interferon induced transmembrane protein 3	0.484
Ambp	alpha-1-microglobulin/bikunin precursor	0.343
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.331	Human
Gc	group specific component	0.320
Ccl2	chemokine (C-C motif) ligand 2	0.251
Cp	ceruloplasmin	0.238
F2	coagulation factor II (thrombin)	0.211	Human Rat
Icam1	intercellular adhesion molecule 1	0.174
Ahsg	alpha-2-HS-glycoprotein	0.154
Mdfic	MyoD family inhibitor domain containing	0.147
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.145
Proc	protein C	0.125	Rat
C1r	complement component 1, r subcomponent	0.104
Fabp1	fatty acid binding protein 1, liver	0.103
Plg	plasminogen	0.103	Human
Cfi	complement factor I	0.091
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.087
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.086
Pla1a	phospholipase A1 member A	0.079
Serpinf2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.077
Cxcl13	chemokine (C-X-C motif) ligand 13	0.076
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.076
Spp2	secreted phosphoprotein 2	0.075
Apoa2	apolipoprotein A-II	0.074
Cfb	complement factor B	0.072
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.068
Qprt	quinolinate phosphoribosyltransferase	0.065
Mbl1	mannose-binding lectin (protein A) 1	0.065
Dnase1l3	deoxyribonuclease 1-like 3	0.065
Fga	fibrinogen alpha chain	0.064
Alb	albumin	0.063
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.063
Mbl2	mannose-binding lectin (protein C) 2	0.061
Cpb2	carboxypeptidase B2 (plasma)	0.060
Hpn	hepsin	0.058
Asgr2	asialoglycoprotein receptor 2	0.056
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.053
Lpl	lipoprotein lipase	0.049
C3	complement component 3	0.049
Hdc	histidine decarboxylase	0.047
Hpx	hemopexin	0.045
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.044
Fgg	fibrinogen gamma chain	0.043
Serpinc1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.042
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.042
Btg1	B-cell translocation gene 1, anti-proliferative	0.039
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.038
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.038
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.038
Srgn	serglycin	0.037
Ttr	transthyretin	0.037
Il1b	interleukin 1 beta	0.037
Nfe2	nuclear factor, erythroid derived 2	0.034
Plau	plasminogen activator, urokinase	0.032
Apom	apolipoprotein M	0.032
Fetub	fetuin B	0.032
Axl	Axl receptor tyrosine kinase	0.031
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.031
Otc	ornithine carbamoyltransferase	0.030
Cma1	chymase 1, mast cell	0.030
Afp	alpha-fetoprotein	0.029
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.029
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.029
C4b	complement component 4B (Chido blood group)	0.028
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.028
RGD1564614	similar to complement factor H-related protein	0.027
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.026
Tlr7	toll-like receptor 7	0.026
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.026
F10	coagulation factor X	0.025	Rat
Gulo	gulonolactone (L-) oxidase	0.025
Aqp9	aquaporin 9	0.025
Col18a1	collagen, type XVIII, alpha 1	0.024
Aebp1	AE binding protein 1	0.024
Apoc4	apolipoprotein C-IV	0.023
Cyp2d1	cytochrome P450, family 2, subfamily d, polypeptide 1	0.023
C9	complement component 9	0.023
Gata1	GATA binding protein 1	0.023
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.023
Rup2	urinary protein 2	0.023
C4bpa	complement component 4 binding protein, alpha	0.022
C2	complement component 2	0.022
Gys2	glycogen synthase 2	0.022
Pcsk9	proprotein convertase subtilisin/kexin type 9	0.022
Lrrc26	leucine rich repeat containing 26	0.022
Lipc	lipase, hepatic	0.022
Srpx	sushi-repeat-containing protein, X-linked	0.022
LOC100365106	rCG32755-like	0.022
Tgfbi	transforming growth factor, beta induced	0.022
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.021
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.021
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.020
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.020
Agmat	agmatine ureohydrolase (agmatinase)	0.020
Igfbp1	insulin-like growth factor binding protein 1	0.020
Ccl3	chemokine (C-C motif) ligand 3	0.020
Anxa3	annexin A3	0.020
Cd83	CD83 molecule	0.020
Ier3	immediate early response 3	0.020
C8b	complement component 8, beta polypeptide	0.020
Arl11	ADP-ribosylation factor-like 11	0.019
Dram	damage-regulated autophagy modulator	0.019
Rarres2	retinoic acid receptor responder (tazarotene induced) 2	0.019
Gzmk	granzyme K	0.019
Capn2	calpain 2	0.019
Crispld2	cysteine-rich secretory protein LCCL domain containing 2	0.019
Ang1	angiogenin, ribonuclease A family, member 1	0.019
Pawr	PRKC, apoptosis, WT1, regulator	0.018
Agtr1a	angiotensin II receptor, type 1a	0.018
Hpd	4-hydroxyphenylpyruvate dioxygenase	0.018
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.018
Adamts9	a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9	0.018
Klkb1	kallikrein B, plasma 1	0.018
Runx1	runt-related transcription factor 1	0.018
Cd302	CD302 molecule	0.018
Pck1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.018
Kng2	kininogen 2	0.018
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.017
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.017
Lbp	lipopolysaccharide binding protein	0.017
F12	coagulation factor XII (Hageman factor)	0.017	Human
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.017
Tssk2	testis-specific serine kinase 2	0.017
Postn	periostin, osteoblast specific factor	0.017
Best2	bestrophin 2	0.017
Cideb	cell death-inducing DFFA-like effector b	0.017
C1qc	complement component 1, q subcomponent, C chain	0.017
Aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.017
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.016
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.016
Atf3	activating transcription factor 3	0.016
Htra1	HtrA serine peptidase 1	0.016
Cav3	caveolin 3	0.016
Ghr	growth hormone receptor	0.016
Gbp2	guanylate binding protein 2	0.016
Amy2	amylase 2, pancreatic	0.016
Lrp1	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	0.016
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.016
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.016
Vcan	versican	0.016
Hp	haptoglobin	0.016
Ttc36	tetratricopeptide repeat domain 36	0.016
RGD1306625	LOC360508	0.016
Ddc8	differential display clone 8	0.016
Lao1	L-amino acid oxidase 1	0.016
Apob	apolipoprotein B	0.016
Rhd	Rh blood group, D antigen	0.015
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.015
Tf	transferrin	0.015
Plaur	plasminogen activator, urokinase receptor	0.015
Col8a1	collagen, type VIII, alpha 1	0.015
Kng1	kininogen 1	0.015
Rnase4	ribonuclease, RNase A family 4	0.015
LOC299282	Serine protease inhibitor	0.015
Myog	myogenin	0.015
Ramp1	receptor (G protein-coupled) activity modifying protein 1	0.015
Actn1	actinin, alpha 1	0.015
Creb3l3	cAMP responsive element binding protein 3-like 3	0.015
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.015
Adamts1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.015
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.015
Cpn1	carboxypeptidase N, polypeptide 1	0.015
Aqp7	aquaporin 7	0.014
Vcam1	vascular cell adhesion molecule 1	0.014
Cnr2	cannabinoid receptor 2 (macrophage)	0.014
Ltbp1	latent transforming growth factor beta binding protein 1	0.014
Colec11	collectin sub-family member 11	0.014
Masp2	mannan-binding lectin serine peptidase 2	0.014
Il6r	interleukin 6 receptor	0.014
LOC100362634	myeloid/lymphoid or mixed-lineage leukemia 2	0.014
Twist2	twist homolog 2 (Drosophila)	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A	0.014
LOC680875	similar to dystonin isoform 1	0.014
Pitx2	paired-like homeodomain 2	0.014
Spink8	serine peptidase inhibitor, Kazal type 8	0.014
Il6st	interleukin 6 signal transducer	0.014
RT1-Db1	RT1 class II, locus Db1	0.014
Slc44a1	solute carrier family 44, member 1	0.014
Tpsab1	tryptase alpha/beta 1	0.014
Plod2	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2	0.013
Prss3	protease, serine, 3	0.013
Kcns3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.013
Hmox1	heme oxygenase (decycling) 1	0.013
RGD1311307	similar to 1300014I06Rik protein	0.013
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.013
Erp27	endoplasmic reticulum protein 27	0.013
Hgfac	hepatocyte growth factor activator	0.013
Pon1	paraoxonase 1	0.013
Serpinb9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.013
Vtn	vitronectin	0.013
Plat	plasminogen activator, tissue	0.013
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.013
Foxa2	forkhead box A2	0.013
E2f5	E2F transcription factor 5	0.013
Oaf	OAF homolog (Drosophila)	0.013
Gnat3	guanine nucleotide binding protein, alpha transducing 3	0.013
Theg	testicular haploid expressed gene	0.012
LOC100361724	cytochrome P450 2B3-like	0.012
Saa4	serum amyloid A4, constitutive	0.012
Pim1	pim-1 oncogene	0.012
RGD1564865	similar to 20-alpha-hydroxysteroid dehydrogenase	0.012
Ces1d	carboxylesterase 1D	0.012
Fads1	fatty acid desaturase 1	0.012
Ctgf	connective tissue growth factor	0.012
Mcpt1	mast cell protease 1	0.012
Trex2	three prime repair exonuclease 2	0.012
Man1a1	mannosidase, alpha, class 1A, member 1	0.012
Tmem8c	transmembrane protein 8C	0.012
Rhoj	ras homolog gene family, member J	0.012
Gldc	glycine dehydrogenase (decarboxylating)	0.012
Irf1	interferon regulatory factor 1	0.012
Rnase2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.012
Pgcp	plasma glutamate carboxypeptidase	0.012
F3	coagulation factor III (thromboplastin, tissue factor)	0.012
Cpz	carboxypeptidase Z	0.012
Rgs1	regulator of G-protein signaling 1	0.012
C6	complement component 6	0.012
Fabp4	fatty acid binding protein 4, adipocyte	0.012
Stat3	signal transducer and activator of transcription 3	0.012
Rrad	Ras-related associated with diabetes	0.012
Ugt1a5	UDP glucuronosyltransferase 1 family, polypeptide A5	0.011
Lzts1	leucine zipper, putative tumor suppressor 1	0.011
Tbc1d2b	TBC1 domain family, member 2B	0.011
Amy1a	amylase, alpha 1A (salivary)	0.011
Ddx21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.011
Agxt2	alanine-glyoxylate aminotransferase 2	0.011
LOC360919	similar to alpha-fetoprotein	0.011
Ggn	gametogenetin	0.011
Casp12	caspase 12	0.011
Nupr1	nuclear protein, transcriptional regulator, 1	0.011
Cd7	Cd7 molecule	0.011
Ctse	cathepsin E	0.011
Prom2	prominin 2	0.011
RGD1308065	hypothetical LOC287935	0.011
A1i3	alpha-1-inhibitor III	0.011
Csrp3	cysteine and glycine-rich protein 3	0.011
Xdh	xanthine dehydrogenase	0.011
Bfsp1	beaded filament structural protein 1	0.011
C4-2	complement component 4, gene 2	0.011
Lox	lysyl oxidase	0.011
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.011
Mug1	murinoglobulin 1	0.011
Fat1	FAT tumor suppressor homolog 1 (Drosophila)	0.011
Onecut1	one cut homeobox 1	0.011
RT1-S3	RT1 class Ib, locus S3	0.011
Krt86	keratin 86	0.011
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.011
Ptprm	protein tyrosine phosphatase, receptor type, M	0.011
Tchh	trichohyalin	0.011
Ctrc	chymotrypsin C (caldecrin)	0.011
Nags	N-acetylglutamate synthase	0.011
Tubb2b	tubulin, beta 2b	0.011
Pdpn	podoplanin	0.011
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.010
Apoa5	apolipoprotein A-V	0.010
Atp6ap1l	ATPase, H+ transporting, lysosomal accessory protein 1-like	0.010
Arhgap25	Rho GTPase activating protein 25	0.010
Dpp4	dipeptidylpeptidase 4	0.010
Actc1	actin, alpha, cardiac muscle 1	0.010
Bmp2	bone morphogenetic protein 2	0.010
Sdc4	syndecan 4	0.010
S1pr3	sphingosine-1-phosphate receptor 3	0.010
LOC305633	similar to Antxr2 protein	0.010
Bhmt	betaine-homocysteine methyltransferase	0.010
Enpp3	ectonucleotide pyrophosphatase/phosphodiesterase 3	0.010