IMP

Process View

Danio rerio

2 genes annotated in zebrafish

negative regulation of oocyte development

Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of oocyte development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of oocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
chd	chordin	0.426
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.381
ptch1	patched 1	0.348
bmp2b	bone morphogenetic protein 2b	0.345
lamb1a	laminin, beta 1a	0.314
mespb	mesoderm posterior b	0.259
vent	ventral expressed homeobox	0.238
sox32	SRY-box containing gene 32	0.238
dharma	dharma	0.229
ihha	Indian hedgehog homolog a	0.224
furina	furin (paired basic amino acid cleaving enzyme) a	0.211
tll1	tolloid-like 1	0.196
ndr1	nodal-related 1	0.146
foxi1	forkhead box I1	0.118
bon	bonnie and clyde	0.094
mxtx2	mix-type homeobox gene 2	0.093
sox9b	SRY-box containing gene 9b	0.091
pnx	posterior neuron-specific homeobox	0.090
tbx16	T-box gene 16	0.087
vangl2	vang-like 2 (van gogh, Drosophila)	0.087
ptch2	patched 2	0.086
lepr	leptin receptor	0.086
bmp7a	bone morphogenetic protein 7a	0.085	Zebrafish
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.084
admp	anti-dorsalizing morphogenic protein	0.082	Zebrafish
tbx24	T-box 24	0.073
her7	hairy and enhancer of split related-7	0.061
zgc:56039	zgc:56039	0.059
ndr2	nodal-related 2	0.056
acvr2a	activin receptor IIa	0.056
chsy1	chondroitin sulfate synthase 1	0.051
fzd5	frizzled homolog 5	0.051
jag1b	jagged 1b	0.050
sox17	SRY-box containing gene 17	0.050
twsg1b	twisted gastrulation homolog 1b (Drosophila)	0.049
acvr1b	activin A receptor, type IB	0.047
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.045
twist1b	twist1b	0.044
syce2	synaptonemal complex central element protein 2	0.043
mespa	mesoderm posterior a	0.043
jmjd6	jumonji domain containing 6	0.043
fgfrl1b	fibroblast growth factor receptor-like 1b	0.039
frem2a	Fras1 related extracellular matrix protein 2a	0.036
zgc:100838	zgc:100838	0.036
rxrbb	retinoid x receptor, beta b	0.036
cdx4	caudal type homeo box transcription factor 4	0.035
scinla	scinderin like a	0.034
rest	RE1-silencing transcription factor	0.034
sox9a	SRY-box containing gene 9a	0.033
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.033
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.032
zgc:56409	zgc:56409	0.032
satb2	SATB homeobox 2	0.031
foxd5	forkhead box D5	0.031
tbx6	T-box gene 6	0.029
lrrc50	leucine rich repeat containing 50	0.029
sox8	SRY-box containing gene 8	0.028
mitfa	microphthalmia-associated transcription factor a	0.027
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.026
si:dkey-204a24.9	si:dkey-204a24.9	0.026
flh	floating head	0.026
tgfb2	transforming growth factor, beta 2	0.026
hand2	heart and neural crest derivatives expressed transcript 2	0.025
wnt10a	wingless-type MMTV integration site family, member 10a	0.025
LOC554173	abnormal spindles	0.025
suv39h1a	suppressor of variegation 3-9 homolog 1a	0.025
srf	serum response factor	0.025
map2k4a	mitogen-activated protein kinase kinase 4a	0.025
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.025
gpr126	G protein-coupled receptor 126	0.024
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.024
zgc:64177	zgc:64177	0.024
ahi1	Abelson helper integration site 1	0.023
mchr1b	melanin-concentrating hormone receptor 1b	0.023
runx2b	runt-related transcription factor 2b	0.023
fshr	follicle stimulating hormone receptor	0.022
foxa3	forkhead box A3	0.022
msxd	muscle segment homeobox D	0.022
pkd2	polycystic kidney disease 2	0.022
col27a1a	collagen, type XXVII, alpha 1a	0.022
snai1b	snail homolog 1b (Drosophila)	0.021
zbtb22b	zinc finger and BTB domain containing 22b	0.020
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.020
nkx2.3	NK2 transcription factor related 3	0.020
prdm1a	PR domain containing 1a, with ZNF domain	0.020
hoxd11a	homeo box D11a	0.020
eif2ak3	eukaryotic translation initiation factor 2-alpha kinase 3	0.020
dlx2a	distal-less homeobox gene 2a	0.020
sall4	sal-like 4 (Drosophila)	0.020
cldnd	claudin d	0.020
cdx1b	caudal type homeobox 1 b	0.019
msxb	muscle segment homeobox B	0.019
retsatl	retinol saturase (all-trans-retinol 13,14-reductase) like	0.019
fgfrl1a	fibroblast growth factor receptor-like 1a	0.019
col8a1a	collagen, type VIII, alpha 1a	0.018
nr6a1a	nuclear receptor subfamily 6, group A, member 1a	0.018
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.018
ved	ventrally expressed dharma/bozozok antagonist	0.018
notch1a	notch homolog 1a	0.018
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.018
frem3	Fras1 related extracellular matrix 3	0.018
ripply2	ripply2	0.017
slc8a4b	solute carrier family 8 (sodium/calcium exchanger), member 4b	0.017
hoxa9b	homeo box A9b	0.017
cep70	centrosomal protein 70	0.017
eve1	even-skipped-like1	0.017
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.017
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.017
hoxd12a	homeo box D12a	0.017
pcdh8	protocadherin 8	0.016
wu:fk76c08	wu:fk76c08	0.016
angpt1	angiopoietin 1	0.016
pcdh18b	protocadherin 18b	0.016
piwil2	piwi-like 2 (Drosophila)	0.016
cdx1a	caudal type homeo box transcription factor 1 a	0.015
bmp2a	bone morphogenetic protein 2a	0.015
gli1	GLI-Kruppel family member 1	0.015
ptgs1	prostaglandin-endoperoxide synthase 1	0.015
wu:fc18c07	wu:fc18c07	0.015
scrib	scribbled homolog (Drosophila)	0.015
her1	hairy-related 1	0.015
gsdf	gonadal somatic cell derived factor	0.015
hgfa	hepatocyte growth factor a	0.015
akt2	v-akt murine thymoma viral oncogene homolog 2	0.015
acvr2b	activin receptor IIb	0.015
ednra	endothelin receptor type A	0.014
hoxa10b	homeo box A10b	0.014
si:dkey-97i18.2	si:dkey-97i18.2	0.014
ankrd6	ankyrin repeat domain 6	0.014
tp73	tumor protein p73	0.014
foxj1a	forkhead box J1a	0.014
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.014
rxrba	retinoid x receptor, beta a	0.014
runx2a	runt-related transcription factor 2a	0.014
met	met proto-oncogene (hepatocyte growth factor receptor)	0.013
disp1	dispatched homolog 1 (Drosophila)	0.013
raf1a	v-raf-1 murine leukemia viral oncogene homolog 1a	0.013
cry2b	cryptochrome 2b	0.013
ntla	no tail a	0.013
cax1	cation/H+ exchanger protein 1	0.013
si:ch211-1n9.7	si:ch211-1n9.7	0.013
bmp7b	bone morphogenetic protein 7b	0.013	Zebrafish
rag2	recombination activating gene 2	0.013
gdf6b	growth differentiation factor 6b	0.013	Zebrafish
rpgrb	retinitis pigmentosa GTPase regulator b	0.013
zgc:77051	zgc:77051	0.013
sp7	Sp7 transcription factor	0.013
pglyrp2	peptidoglycan recognition protein 2	0.013
lmna	lamin A	0.013
ctgf	connective tissue growth factor	0.013
cpla2	cytosolic phospholipase a2	0.013
im:7138239	im:7138239	0.013
ntf7	neurotrophin 7	0.012
foxh1	forkhead box H1	0.012
dcc	deleted in colorectal carcinoma	0.012
glud1b	glutamate dehydrogenase 1b	0.012
sec61al1	Sec61 alpha like 1	0.012
six4.3	sine oculis homeobox homolog 4.3	0.012
nog3	noggin 3	0.012
cx41.8	connexin 41.8	0.012
gadd45ab	growth arrest and DNA-damage-inducible, alpha, b	0.012
shha	sonic hedgehog a	0.012
fibin	fin bud initiation factor	0.012
hhex	hematopoietically expressed homeobox	0.012
glulb	glutamate-ammonia ligase (glutamine synthase) b	0.011
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.011
slc12a9	solute carrier family 12 (potassium/chloride transporters), member 9	0.011
si:ch211-173p18.9	si:ch211-173p18.9	0.011
dkk1b	dickkopf 1b	0.011
tbx20	T-box 20	0.011
insb	preproinsulin b	0.011
hoxa11a	homeo box A11a	0.011
her5	hairy-related 5	0.011
brd2b	bromodomain containing 2b	0.011
lmo4a	LIM domain only 4a	0.011
mtnr1ba	melatonin receptor type 1B a	0.011
cnot3b	CCR4-NOT transcription complex, subunit 3b	0.011
gbx2	gastrulation brain homeo box 2	0.011
fstl1a	follistatin-like 1a	0.011
nkx1.2la	NK1 transcription factor related 2-like,a	0.011
zgc:123282	zgc:123282	0.011
tbx2b	T-box 2b	0.011
cyp2aa4	cytochrome P450, family 2, subfamily AA, polypeptide 4	0.011
LOC567678	avidin-like	0.011
insrb	insulin receptor b	0.010
prrx1a	paired related homeobox 1a	0.010
twist3	twist3	0.010
si:ch211-173o4.2	si:ch211-173o4.2	0.010
ms4a17a.11	membrane-spanning 4-domains, subfamily A, member 17A.11	0.010
plxnb2a	plexin b2a	0.010
vox	ventral homeobox	0.010
plagl2	pleiomorphic adenoma gene-like 2	0.010
slc14a2	solute carrier family 14 (urea transporter), member 2	0.010
otx1a	orthodenticle homolog 1a	0.010
sgk1	serum/glucocorticoid regulated kinase 1	0.010
LOC100330224	fatty acid binding protein 1b-like	0.010
hibadha	3-hydroxyisobutyrate dehydrogenase a	0.010
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.010