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Danio rerio

8 genes annotated in zebrafish

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regulation of axon guidance

GO:1902667

Any process that modulates the frequency, rate or extent of axon guidance.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of axon guidance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
robo3	roundabout homolog 3	0.945	Zebrafish
bmp2a	bone morphogenetic protein 2a	0.917
robo1	roundabout homolog 1	0.912	Zebrafish
lhx2b	LIM homeobox 2b	0.870
lef1	lymphocyte enhancer binding factor 1	0.826
wnt4a	wingless-type MMTV integration site family, member 4a	0.815
tbx1	T-box 1	0.786
wnt8b	wingless-type MMTV integration site family, member 8b	0.714	Zebrafish
sim1a	single-minded homolog 1a (Drosophila)	0.582
otx5	orthodenticle homolog 5	0.557
wnt1	wingless-type MMTV integration site family, member 1	0.543	Zebrafish
slit3	slit (Drosophila) homolog 3	0.394	Worm
fezf2	FEZ family zinc finger 2	0.340
rdh10a	retinol dehydrogenase 10a	0.297
flot1	flotillin 1	0.291
nrp2b	neuropilin 2b	0.260
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.258	Worm
wnt3	wingless-type MMTV integration site family, member 3	0.235	Zebrafish Mouse
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.230
itgav	integrin, alpha V	0.223
mecom	MDS1 and EVI1 complex locus	0.213
twist3	twist3	0.213
ntn1b	netrin 1b	0.207	Fly
grem2	gremlin 2, cysteine knot superfamily	0.196
crestin	crestin	0.195
dlx2a	distal-less homeobox gene 2a	0.195
foxp2	forkhead box P2	0.186
wnt3a	wingless-type MMTV integration site family, member 3A	0.179	Zebrafish Mouse
sema3d	semaphorin 3d	0.163
lhx3	LIM homeobox 3	0.162
shha	sonic hedgehog a	0.157
eng1a	engrailed 1a	0.149
fgf3	fibroblast growth factor 3	0.147	Worm
vcanb	versican b	0.135
myf5	myogenic factor 5	0.119
tbx2b	T-box 2b	0.118
esrrga	estrogen-related receptor gamma a	0.116
lhx6	LIM homeobox 6	0.116
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.112
isl2a	islet2a	0.110
vax2	ventral anterior homeobox 2	0.106
rx3	retinal homeobox gene 3	0.106
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.101
ret1	receptor tyrosine kinase	0.100
tbx2a	T-box gene 2a	0.097
vcana	versican a	0.095
sulf1	sulfatase 1	0.095
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.090
slit2	slit (Drosophila) homolog 2	0.089	Human Worm
ntn1a	netrin 1a	0.083	Fly
barhl2	BarH-like 2	0.081
tbx4	T-box 4	0.077
spry4	sprouty (Drosophila) homolog 4	0.075
phox2a	paired-like homeobox 2a	0.074
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.074	Zebrafish
mapk14a	mitogen-activated protein kinase 14a	0.073
arx	aristaless related homeobox	0.073
dbx1a	developing brain homeobox 1a	0.072
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.069	Zebrafish
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.069
mmp2	matrix metalloproteinase 2	0.067
her15.1	hairy and enhancer of split-related 15.1	0.064
slit1a	slit homolog 1a (Drosophila)	0.062	Rat Worm
dld	deltaD	0.061
zgc:77752	zgc:77752	0.060
flh	floating head	0.059
wls	wntless homolog (Drosophila)	0.059
lmo4a	LIM domain only 4a	0.058
osr2	odd-skipped related 2 (Drosophila)	0.057
nrp1a	neuropilin 1a	0.055	Mouse
efnb2a	ephrin B2a	0.055
boc	brother of CDO	0.054
klf4a	Kruppel-like transcription factor 4a	0.052
foxd3	forkhead box D3	0.052
gfra1a	gdnf family receptor alpha 1a	0.052
cdh2	cadherin 2, neuronal	0.051
wnt9b	wingless-type MMTV integration site family, member 9B	0.050	Zebrafish
sox2	SRY-box containing gene 2	0.050
fzd7a	frizzled homolog 7a	0.050
etv2	ets variant gene 2	0.048
tbx5a	T-box 5a	0.047
gli1	GLI-Kruppel family member 1	0.047
myod1	myogenic differentiation 1	0.047
epb4.1l4	erythrocyte protein band 4.1-like 4	0.047
pcdh10b	protocadherin 10b	0.047
neo1	neogenin 1	0.047
hoxa13b	homeo box A13b	0.046
pcdh19	protocadherin 19	0.045
wnt10a	wingless-type MMTV integration site family, member 10a	0.045	Zebrafish
cntn2	contactin 2	0.044
exorh	extra-ocular rhodopsin	0.044
vax1	ventral anterior homeobox 1	0.044
sox4b	SRY-box containing gene 4b	0.043
epha4a	eph receptor A4a	0.043
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.042
slit1b	slit homolog 1b (Drosophila)	0.042	Rat Worm
rxrab	retinoid x receptor, alpha b	0.042
gli2a	GLI-Kruppel family member GLI2a	0.042
msxd	muscle segment homeobox D	0.040
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.039
sema3gb	semaphorin 3gb	0.039
ptch2	patched 2	0.038
irx2a	iroquois homeobox protein 2, a	0.038
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.037
olig2	oligodendrocyte lineage transcription factor 2	0.037
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.037
pea3	ETS-domain transcription factor pea3	0.037
sema3aa	semaphorin 3aa	0.037	Human Mouse
dab1b	disabled homolog 1b (Drosophila)	0.036
bmp4	bone morphogenetic protein 4	0.036
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.034	Zebrafish
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.034
osr1	odd-skipped related 1 (Drosophila)	0.034
zbtb4	zinc finger and BTB domain containing 4	0.034
ldb2a	LIM-domain binding factor 2a	0.034
tgfb3	transforming growth factor, beta 3	0.034
hmx1	H6 homeo box 1	0.034
otpa	orthopedia homolog a	0.033
gbx2	gastrulation brain homeo box 2	0.033
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.033
phox2b	paired-like homeobox 2b	0.032
tgfb2	transforming growth factor, beta 2	0.032
wnt5b	wingless-type MMTV integration site family, member 5b	0.032	Zebrafish Mouse
evx1	even-skipped homeobox 1	0.032
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.031
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.030
im:7162646	im:7162646	0.030
pcdh18b	protocadherin 18b	0.029
aanat2	arylalkylamine N-acetyltransferase	0.029
brd4	bromodomain containing 4	0.029
nos1	nitric oxide synthase 1 (neuronal)	0.029
eng2a	engrailed 2a	0.028
sp8a	sp8 transcription factor a	0.028
axin1	axin 1	0.028
skia	nuclear oncoprotein skia	0.027
rorcb	RAR-related orphan receptor C b	0.027
hoxa11a	homeo box A11a	0.027
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.027
ptrfb	polymerase I and transcript release factor b	0.026
wnt2	wingless-type MMTV integration site family member 2	0.026	Zebrafish
zmynd11	zinc finger, MYND domain containing 11	0.026
sfrp1a	secreted frizzled-related protein 1a	0.025
dlx5a	distal-less homeobox gene 5a	0.025
otx2	orthodenticle homolog 2	0.025
onecutl	one cut domain, family member, like	0.024
wtip	Wilms tumor 1 interacting protein	0.024
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.024
slc25a3a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a	0.023
dlx2b	distal-less homeobox gene 2b	0.023
ebf3	early B-cell factor 3	0.023
znf503	zinc finger protein 503	0.023
tbx18	T-box 18	0.023
map2k4a	mitogen-activated protein kinase kinase 4a	0.023
fgfrl1b	fibroblast growth factor receptor-like 1b	0.022
wnt16	wingless-type MMTV integration site family, member 16	0.022
nadl1.1	neural adhesion molecule L1.1	0.022
col14a1	collagen, type XIV, alpha 1	0.022
foxa1	forkhead box A1	0.021
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.021
ptprf	protein tyrosine phosphatase, receptor type, F	0.021
angpt1	angiopoietin 1	0.021
fbln1	fibulin 1	0.021
dpysl2b	dihydropyrimidinase-like 2b	0.021
gngt2a	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a	0.021
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.020
insm1a	insulinoma-associated 1a	0.020
frem3	Fras1 related extracellular matrix 3	0.020
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.020
hoxa13a	homeo box A13a	0.020
fgfr1a	fibroblast growth factor receptor 1a	0.020
unc5b	unc-5 homolog B (C. elegans)	0.020
tcf21	transcription factor 21	0.020
mapk6	mitogen-activated protein kinase 6	0.020
pp	pyrophosphatase (inorganic)	0.019
gle1	GLE1 RNA export mediator homolog (yeast)	0.019
nrp2a	neuropilin 2a	0.019
dusp6	dual specificity phosphatase 6	0.019
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.018
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.018
pdlim3b	PDZ and LIM domain 3b	0.018
met	met proto-oncogene (hepatocyte growth factor receptor)	0.018
nkd2	naked cuticle homolog 2 and naked 2a	0.018
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.018
coe2	coe2	0.018
sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.017
neurog1	neurogenin 1	0.017
hhip	hedgehog interacting protein	0.017
rx2	retinal homeobox gene 2	0.017
fgf24	fibroblast growth factor 24	0.017
bmp1a	bone morphogenetic protein 1a	0.017
vsx1	visual system homeobox 1 homolog, chx10-like	0.017
dla	deltaA	0.017
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.017
si:dkey-273o13.1	si:dkey-273o13.1	0.017
emx3	empty spiracles homeobox 3	0.017
fras1	Fraser syndrome 1	0.017
csnk1a1	casein kinase 1, alpha 1	0.017
igfbp3	insulin-like growth factor binding protein 3	0.017
jag2	jagged 2	0.017
itgb3b	integrin beta 3b	0.017
drd3	dopamine receptor D3	0.016
nr4a2a	nuclear receptor subfamily 4, group A, member 2a	0.016
ext2	exostoses (multiple) 2	0.016
pitx3	paired-like homeodomain transcription factor 3	0.016
hmx4	H6 family homeobox 4	0.016
csnk1da	casein kinase 1, delta a	0.016
fgf10a	fibroblast growth factor 10a	0.016	Worm
pax8	paired box gene 8	0.015
traf4a	tnf receptor-associated factor 4a	0.015
fgfr3	fibroblast growth factor receptor 3	0.015
msi1	musashi homolog 1 (Drosophila)	0.015
tal2	T-cell acute lymphocytic leukemia 2	0.015
nav3	neuron navigator 3	0.015
map2k7	mitogen-activated protein kinase kinase 7	0.015
hoxd4a	homeo box D4a	0.015
slc4a2a	solute carrier family 4, anion exchanger, member 2a	0.015
tpbgl	trophoblast glycoprotein-like	0.015
mc3r	melanocortin 3 receptor	0.015
robo2	roundabout homolog 2	0.015
dcc	deleted in colorectal carcinoma	0.015
ptk2.1	protein tyrosine kinase 2a	0.015
glceb	glucuronyl C5-epimerase b	0.015
plxnb2a	plexin b2a	0.014
fgf19	fibroblast growth factor 19	0.014
zgc:92218	zgc:92218	0.014
smad9	MAD homolog 9 (Drosophila)	0.014
LOC100002342	carboxypeptidase A6-like	0.014
gja3	gap junction protein, alpha 3	0.014
rbl1	retinoblastoma-like 1 (p107)	0.014
irx1a	iroquois homeobox protein 1, a	0.014
pvrl1a	poliovirus receptor-related 1a	0.014
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.014
zgc:114181	zgc:114181	0.013
igf1ra	insulin-like growth factor 1a receptor	0.013
nkx2.1a	NK2 homeobox 1a	0.013
efnb1	ephrin B1	0.013
id:ibd2808	id:ibd2808	0.013
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.013
plxnb2b	plexin b2b	0.013
hoxb3a	homeo box B3a	0.013
chrna4	cholinergic receptor, nicotinic, alpha 4	0.013
pax7a	paired box gene 7a	0.013
egr2b	early growth response 2b	0.013
igf1rb	insulin-like growth factor 1b receptor	0.013
mapk4	mitogen-activated protein kinase 4	0.013
raraa	retinoic acid receptor, alpha a	0.012
hmx3	homeo box (H6 family) 3	0.012
fgf17	fibroblast growth factor 17	0.012
alcama	activated leukocyte cell adhesion molecule a	0.012
pax6a	paired box gene 6a	0.012
tbx5b	T-box 5b	0.012
ism1	isthmin 1	0.012
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.012
mapk7	mitogen-activated protein kinase 7	0.012
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.012
fsta	follistatin a	0.012
myf6	myogenic factor 6	0.012
msxb	muscle segment homeobox B	0.012
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.012
flt4	fms-related tyrosine kinase 4	0.012
nkx3.2	NK3 homeobox 2	0.012
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.012
tbx20	T-box 20	0.011
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.011
map2k4b	mitogen-activated protein kinase kinase 4b	0.011
sema3ga	semaphorin 3ga	0.011
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
hdac4	histone deacetylase 4	0.011
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.011
nog2	noggin 2	0.011
pax2a	paired box gene 2a	0.011
midn	midnolin	0.011
pou3f3b	POU class 3 homeobox 3b	0.011
msxa	muscle segment homeobox A	0.011
dharma	dharma	0.011
unc5db	unc-5 homolog Db (C. elegans)	0.011
drgx	dorsal root ganglia homeobox	0.011
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.011
msxc	muscle segment homeobox C	0.011
irx4a	iroquois homeobox protein 4a	0.011
wnt5a	wingless-type MMTV integration site family, member 5a	0.011	Zebrafish
cadps2	Ca2+-dependent activator protein for secretion 2	0.011
oprm1	opioid receptor, mu 1	0.011
pdx1	pancreatic and duodenal homeobox 1	0.011
nadl1.2	neural adhesion molecule L1.2	0.011
msxe	muscle segment homeobox E	0.011
olfm2	olfactomedin 2	0.011
hlxb9lb	homeo box HB9 like b	0.011
cdh6	cadherin 6	0.011
chrna6	cholinergic receptor, nicotinic, alpha 6	0.011
ntn2	netrin 2	0.010
fgf8b	fibroblast growth factor 8 b	0.010
scrt1b	scratch homolog 1, zinc finger protein b (Drosophila)	0.010
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.010	Zebrafish
efna2	ephrin A2	0.010
sema3ab	semaphorin 3ab	0.010	Human Mouse
pcdh8	protocadherin 8	0.010
lmbr1l	limb region 1 like	0.010
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.010
mapk12	mitogen-activated protein kinase 12	0.010
chpf	chondroitin polymerizing factor	0.010
kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.010