The network for 'leukocyte apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leukocyte apoptotic process

Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.

Homo sapiens
Name Description Probability Func Analog Organism
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
BCL2 B-cell CLL/lymphoma 2 0.997
CFLAR CASP8 and FADD-like apoptosis regulator 0.975
LCK lymphocyte-specific protein tyrosine kinase 0.960
CCR5 chemokine (C-C motif) receptor 5 0.954
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.947
BIRC3 baculoviral IAP repeat containing 3 0.919
SYK spleen tyrosine kinase 0.914
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.909
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.891
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.866
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.851
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.850
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.850
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.778
SH2D4A SH2 domain containing 4A 0.723
BIRC2 baculoviral IAP repeat containing 2 0.683
BID BH3 interacting domain death agonist 0.681
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.653
IL8 interleukin 8 0.607
BMPR1A bone morphogenetic protein receptor, type IA 0.570
CARD11 caspase recruitment domain family, member 11 0.555
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.544
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.536
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.521
CCR1 chemokine (C-C motif) receptor 1 0.476
GAS6 growth arrest-specific 6 0.465
CCR7 chemokine (C-C motif) receptor 7 0.449
DPP4 dipeptidyl-peptidase 4 0.445
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.391
CXCR4 chemokine (C-X-C motif) receptor 4 0.377
PILRA paired immunoglobin-like type 2 receptor alpha 0.361
BCL2L1 BCL2-like 1 0.340
LAT linker for activation of T cells 0.339
FAS Fas (TNF receptor superfamily, member 6) 0.337
CCL4 chemokine (C-C motif) ligand 4 0.328
CD2 CD2 molecule 0.313
IL10RA interleukin 10 receptor, alpha 0.313
NOXA1 NADPH oxidase activator 1 0.306
CAV1 caveolin 1, caveolae protein, 22kDa 0.305
BAK1 BCL2-antagonist/killer 1 0.292
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.283
AXL AXL receptor tyrosine kinase 0.271
NCF1 neutrophil cytosolic factor 1 0.260
PRKCZ protein kinase C, zeta 0.258
CCL5 chemokine (C-C motif) ligand 5 0.257
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.249
SIGLEC7 sialic acid binding Ig-like lectin 7 0.241
TNF tumor necrosis factor 0.241
ANXA5 annexin A5 0.235
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.224
DLG1 discs, large homolog 1 (Drosophila) 0.215
CD247 CD247 molecule 0.213
VCAM1 vascular cell adhesion molecule 1 0.208
CXCL9 chemokine (C-X-C motif) ligand 9 0.206
TRAF1 TNF receptor-associated factor 1 0.204
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.203
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.194
BAX BCL2-associated X protein 0.192
INSR insulin receptor 0.186
PXMP2 peroxisomal membrane protein 2, 22kDa 0.172
CD48 CD48 molecule 0.166
HK3 hexokinase 3 (white cell) 0.166
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.159
SQSTM1 sequestosome 1 0.158
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.154
VCP valosin containing protein 0.150
TGIF1 TGFB-induced factor homeobox 1 0.144
S100A10 S100 calcium binding protein A10 0.142
IL10 interleukin 10 0.127
BCL2A1 BCL2-related protein A1 0.126
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.120
IL2RB interleukin 2 receptor, beta 0.119
CCL13 chemokine (C-C motif) ligand 13 0.118
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.118
MSN moesin 0.116
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.114
CCL8 chemokine (C-C motif) ligand 8 0.108
CXCL2 chemokine (C-X-C motif) ligand 2 0.107
EP300 E1A binding protein p300 0.106
IL1B interleukin 1, beta 0.104
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.103
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.101
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.101
IL22RA1 interleukin 22 receptor, alpha 1 0.100
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.099
VHL von Hippel-Lindau tumor suppressor 0.096
FADD Fas (TNFRSF6)-associated via death domain 0.094
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.093
XIAP X-linked inhibitor of apoptosis 0.091
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.090
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.088
IDE insulin-degrading enzyme 0.088
PTAFR platelet-activating factor receptor 0.087
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.085
CCL2 chemokine (C-C motif) ligand 2 0.084
PRKCB protein kinase C, beta 0.083
DERL1 Der1-like domain family, member 1 0.083
CCL7 chemokine (C-C motif) ligand 7 0.082
FASLG Fas ligand (TNF superfamily, member 6) 0.079
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Lyz2 lysozyme 2 1.000
Cd44 CD44 antigen 0.997
Ccr1 chemokine (C-C motif) receptor 1 0.988
Ifng interferon gamma 0.978
Cd19 CD19 antigen 0.970
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.963
Ccl2 chemokine (C-C motif) ligand 2 0.956
Il1r1 interleukin 1 receptor, type I 0.939
Il10 interleukin 10 0.937
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.925
Ptprc protein tyrosine phosphatase, receptor type, C 0.894
Cd40 CD40 antigen 0.889
Kit kit oncogene 0.889
Lck lymphocyte protein tyrosine kinase 0.861
Lepr leptin receptor 0.859
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.846
Tnf tumor necrosis factor 0.825
Tlr4 toll-like receptor 4 0.811
Gli3 GLI-Kruppel family member GLI3 0.789
Socs1 suppressor of cytokine signaling 1 0.774
Ptgs2 prostaglandin-endoperoxide synthase 2 0.748
Ccl8 chemokine (C-C motif) ligand 8 0.733
Foxn1 forkhead box N1 0.695
Bcl2 B-cell leukemia/lymphoma 2 0.689
Il2rb interleukin 2 receptor, beta chain 0.684
Inpp5d inositol polyphosphate-5-phosphatase D 0.679
Stat5a signal transducer and activator of transcription 5A 0.679
Igh immunoglobulin heavy chain complex 0.669
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.640
Anxa1 annexin A1 0.624
Hif1a hypoxia inducible factor 1, alpha subunit 0.612
Prf1 perforin 1 (pore forming protein) 0.611
Myd88 myeloid differentiation primary response gene 88 0.610
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.589
Ccl3 chemokine (C-C motif) ligand 3 0.587
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.585
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.570
Cxcl2 chemokine (C-X-C motif) ligand 2 0.537
Meox2 mesenchyme homeobox 2 0.537
Lhx1 LIM homeobox protein 1 0.530
Wnt6 wingless-related MMTV integration site 6 0.527
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.522
Stat5b signal transducer and activator of transcription 5B 0.483
Lep leptin 0.476
Il2rg interleukin 2 receptor, gamma chain 0.470
Csf1 colony stimulating factor 1 (macrophage) 0.464
Pax3 paired box gene 3 0.445
Ccr7 chemokine (C-C motif) receptor 7 0.443
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.430
Trp53 transformation related protein 53 0.421
Ikzf1 IKAROS family zinc finger 1 0.400
Socs3 suppressor of cytokine signaling 3 0.394
Rarg retinoic acid receptor, gamma 0.393
Foxp3 forkhead box P3 0.387
Rxra retinoid X receptor alpha 0.371
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.369
Stat3 signal transducer and activator of transcription 3 0.359
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.357
Il1a interleukin 1 alpha 0.340
Pnp2 purine-nucleoside phosphorylase 2 0.338
Anxa4 annexin A4 0.337
Ccr2 chemokine (C-C motif) receptor 2 0.322
Rara retinoic acid receptor, alpha 0.309
Apc adenomatosis polyposis coli 0.309
Cbl Casitas B-lineage lymphoma 0.289
Pax2 paired box gene 2 0.287
Sh2d2a SH2 domain protein 2A 0.279
Il2 interleukin 2 0.279
Ptf1a pancreas specific transcription factor, 1a 0.273
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.269
Dusp1 dual specificity phosphatase 1 0.268
C3ar1 complement component 3a receptor 1 0.267
Casp8 caspase 8 0.264
Il6 interleukin 6 0.263
Mitf microphthalmia-associated transcription factor 0.261
Gdnf glial cell line derived neurotrophic factor 0.256
Rag2 recombination activating gene 2 0.254
Fgf10 fibroblast growth factor 10 0.249
Pten phosphatase and tensin homolog 0.246
Fgfr2 fibroblast growth factor receptor 2 0.246
Dok1 docking protein 1 0.245
Casp1 caspase 1 0.243
Ctnnb1 catenin (cadherin associated protein), beta 1 0.238
Il1b interleukin 1 beta 0.237
Fcgr1 Fc receptor, IgG, high affinity I 0.235
Insr insulin receptor 0.235
H2-Eb1 histocompatibility 2, class II antigen E beta 0.235
Bax BCL2-associated X protein 0.234
Fcgr2b Fc receptor, IgG, low affinity IIb 0.234
Ccr6 chemokine (C-C motif) receptor 6 0.225
Sfpi1 SFFV proviral integration 1 0.225
Ctsw cathepsin W 0.224
Ubd ubiquitin D 0.222
Mmp9 matrix metallopeptidase 9 0.222
Foxc1 forkhead box C1 0.219
Lif leukemia inhibitory factor 0.219
Was Wiskott-Aldrich syndrome homolog (human) 0.213
Atxn1 ataxin 1 0.213
Il6st interleukin 6 signal transducer 0.212
Adam17 a disintegrin and metallopeptidase domain 17 0.211
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-DMb RT1 class II, locus DMb 0.569
Arpc1b actin related protein 2/3 complex, subunit 1B 0.071
Cd247 Cd247 molecule 0.064
Cd2 Cd2 molecule 0.052
RT1-Ba RT1 class II, locus Ba 0.042
Gzmk granzyme K 0.036
Il2rb interleukin 2 receptor, beta 0.031
Cd44 Cd44 molecule 0.031
C1qc complement component 1, q subcomponent, C chain 0.029
Fgfr2 fibroblast growth factor receptor 2 0.027
Cct4 chaperonin containing Tcp1, subunit 4 (delta) 0.023
Ptprc protein tyrosine phosphatase, receptor type, C 0.023
RT1-Da RT1 class II, locus Da 0.023
RT1-Bb RT1 class II, locus Bb 0.022
Inpp5d inositol polyphosphate-5-phosphatase D 0.021
Tcrb T-cell receptor beta chain 0.020
Ccl3 chemokine (C-C motif) ligand 3 0.019
Gnrhr gonadotropin releasing hormone receptor 0.019
RT1-Db1 RT1 class II, locus Db1 0.018
Sell selectin L 0.016
Ccl2 chemokine (C-C motif) ligand 2 0.015
Hmox1 heme oxygenase (decycling) 1 0.014
Aif1 allograft inflammatory factor 1 0.014
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.013
Laptm5 lysosomal protein transmembrane 5 0.013
Capg capping protein (actin filament), gelsolin-like 0.012
Vcan versican 0.012
Anxa2 annexin A2 0.012
Lat linker for activation of T cells 0.011
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.011
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.010
Lst1 leukocyte specific transcript 1 0.010
Casp1 caspase 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism