The network for 'regulation of microtubule polymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of microtubule polymerization

Any process that modulates the frequency, rate or extent of microtubule polymerization.

Homo sapiens
Name Description Probability Func Analog Organism
MAPT microtubule-associated protein tau 0.957
ZNF746 zinc finger protein 746 0.887
ARL2 ADP-ribosylation factor-like 2 0.872
TERF2IP telomeric repeat binding factor 2, interacting protein 0.787
FYN FYN oncogene related to SRC, FGR, YES 0.711
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.658
KIF5B kinesin family member 5B 0.577
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.536
NEK6 NIMA (never in mitosis gene a)-related kinase 6 0.532
TBCD tubulin folding cofactor D 0.431
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.428
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.376
ERBB2IP erbb2 interacting protein 0.375
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.361
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.337
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.328
CDK2 cyclin-dependent kinase 2 0.308
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.304
FYB FYN binding protein 0.258
LMO2 LIM domain only 2 (rhombotin-like 1) 0.257
GSK3B glycogen synthase kinase 3 beta 0.254
TEX11 testis expressed 11 0.246
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.243
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.236
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.201
DCTN1 dynactin 1 0.189
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.162
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.152
MARK1 MAP/microtubule affinity-regulating kinase 1 0.113
TACC3 transforming, acidic coiled-coil containing protein 3 0.107
FOS FBJ murine osteosarcoma viral oncogene homolog 0.106
SMAD9 SMAD family member 9 0.099
CCDC85A coiled-coil domain containing 85A 0.096
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.093
JUN jun proto-oncogene 0.081
KIF2C kinesin family member 2C 0.076
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 0.073
FNBP1 formin binding protein 1 0.071
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.071
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.062
ARL3 ADP-ribosylation factor-like 3 0.061
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.059
TACC1 transforming, acidic coiled-coil containing protein 1 0.059
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.054
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.054
CLIP1 CAP-GLY domain containing linker protein 1 0.048
TOP3A topoisomerase (DNA) III alpha 0.044
SPTBN1 spectrin, beta, non-erythrocytic 1 0.042
SPRR2A small proline-rich protein 2A 0.041
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.041
VAV1 vav 1 guanine nucleotide exchange factor 0.039
APC adenomatous polyposis coli 0.039
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.038
MAP2K4 mitogen-activated protein kinase kinase 4 0.037
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.037
DST dystonin 0.036
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.036
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.034
ORC1 origin recognition complex, subunit 1 0.032
TUBA4A tubulin, alpha 4a 0.031
GADD45G growth arrest and DNA-damage-inducible, gamma 0.030
LRRK2 leucine-rich repeat kinase 2 0.027
REEP5 receptor accessory protein 5 0.022
BIN1 bridging integrator 1 0.021
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.021
FOXM1 forkhead box M1 0.020
EZR ezrin 0.020
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.020
ZFP106 zinc finger protein 106 homolog (mouse) 0.020
GRAP2 GRB2-related adaptor protein 2 0.019
STIP1 stress-induced-phosphoprotein 1 0.019
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.019
ATM ataxia telangiectasia mutated 0.017
YAP1 Yes-associated protein 1 0.017
GPRASP2 G protein-coupled receptor associated sorting protein 2 0.017
SIAH1 seven in absentia homolog 1 (Drosophila) 0.015
KIF4A kinesin family member 4A 0.015
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.015
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.015
ACD adrenocortical dysplasia homolog (mouse) 0.015
SMC1A structural maintenance of chromosomes 1A 0.015
MTUS2 microtubule associated tumor suppressor candidate 2 0.013
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.013
S100A6 S100 calcium binding protein A6 0.013
NGFR nerve growth factor receptor 0.012
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.012
APC2 adenomatosis polyposis coli 2 0.012
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.012
HSPA1B heat shock 70kDa protein 1B 0.012
PDE4DIP phosphodiesterase 4D interacting protein 0.012
TUBA1C tubulin, alpha 1c 0.012
PDPK1 3-phosphoinositide dependent protein kinase-1 0.012
ZRANB1 zinc finger, RAN-binding domain containing 1 0.011
DUSP1 dual specificity phosphatase 1 0.011
CTNNBL1 catenin, beta like 1 0.011
UBE2B ubiquitin-conjugating enzyme E2B (RAD6 homolog) 0.011
TUBA1B tubulin, alpha 1b 0.011
VAV3 vav 3 guanine nucleotide exchange factor 0.010
SCRIB scribbled homolog (Drosophila) 0.010
LMF2 lipase maturation factor 2 0.010
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
C35E7.8 Protein C35E7.8 0.013
cyl-1 Protein CYL-1 0.013
prp-17 Protein PRP-17 0.013
F43G9.2 Protein F43G9.2 0.012
F42A8.3 Protein F42A8.3 0.011
CELE_Y53C10A.6 Protein Y53C10A.6 0.011
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 0.992
Rb1 retinoblastoma 1 0.904
Ctnnb1 catenin (cadherin associated protein), beta 1 0.608
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.526
Ar androgen receptor 0.435
Apc adenomatosis polyposis coli 0.398
Pten phosphatase and tensin homolog 0.368
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.323
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.285
Cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.227
Kit kit oncogene 0.213
Hr hairless 0.205
Tgfb1 transforming growth factor, beta 1 0.188
Mdm2 transformed mouse 3T3 cell double minute 2 0.184
Ccnd1 cyclin D1 0.163
Braf Braf transforming gene 0.143
Wwox WW domain-containing oxidoreductase 0.118
Lepr leptin receptor 0.118
Ptch1 patched homolog 1 0.118
Tsc1 tuberous sclerosis 1 0.106
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.095
Wdr1 WD repeat domain 1 0.088
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.084
Ahr aryl-hydrocarbon receptor 0.083
Psap prosaposin 0.081
Msh2 mutS homolog 2 (E. coli) 0.065
Gsk3b glycogen synthase kinase 3 beta 0.062
Trp63 transformation related protein 63 0.062
Snap25 synaptosomal-associated protein 25 0.059
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.056
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.055
Stat3 signal transducer and activator of transcription 3 0.054
Arpc4 actin related protein 2/3 complex, subunit 4 0.051
Pot1a protection of telomeres 1A 0.048
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.043
Nf1 neurofibromatosis 1 0.041
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.039
Pacsin1 protein kinase C and casein kinase substrate in neurons 1 0.039
Klf5 Kruppel-like factor 5 0.035
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.031
Tpx2 TPX2, microtubule-associated protein homolog (Xenopus laevis) 0.028
Pcdhgb1 protocadherin gamma subfamily B, 1 0.027
Foxo3 forkhead box O3 0.026
Kiss1r KISS1 receptor 0.025
Nbn nibrin 0.025
Smad3 MAD homolog 3 (Drosophila) 0.025
Klc1 kinesin light chain 1 0.024
Nf2 neurofibromatosis 2 0.023
Notch2 Notch gene homolog 2 (Drosophila) 0.023
Cdk4 cyclin-dependent kinase 4 0.023
Drd2 dopamine receptor D2 0.023
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.022
Mdm4 transformed mouse 3T3 cell double minute 4 0.021
Psen1 presenilin 1 0.021
Irs2 insulin receptor substrate 2 0.020
Esr2 estrogen receptor 2 (beta) 0.018
Lrrk2 leucine-rich repeat kinase 2 0.018
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.018
Acd adrenocortical dysplasia 0.017
Pomc pro-opiomelanocortin-alpha 0.017
Stk11 serine/threonine kinase 11 0.017
Clasp1 CLIP associating protein 1 0.017
Brca1 breast cancer 1 0.016
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.015
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.014
Thbs1 thrombospondin 1 0.014
Gap43 growth associated protein 43 0.013
Rhoa ras homolog gene family, member A 0.013
Fos FBJ osteosarcoma oncogene 0.013
Jak2 Janus kinase 2 0.013
Ncaph non-SMC condensin I complex, subunit H 0.012
Jun Jun oncogene 0.012
Cplx1 complexin 1 0.012
Foxp3 forkhead box P3 0.012
Ptgs1 prostaglandin-endoperoxide synthase 1 0.011
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.011
Hopx HOP homeobox 0.010
Runx1 runt related transcription factor 1 0.010
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.010
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
LOC100362824 caveolin 2-like 0.798
Stip1 stress-induced phosphoprotein 1 0.198
Syt4 synaptotagmin IV 0.146
Errfi1 ERBB receptor feedback inhibitor 1 0.126
Rnf4 ring finger protein 4 0.062
Ehd2 EH-domain containing 2 0.059
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.057
Emp1 epithelial membrane protein 1 0.047
Jak1 Janus kinase 1 0.035
Mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.033
Map2k4 mitogen activated protein kinase kinase 4 0.031
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.028
Bcat1 branched chain aminotransferase 1, cytosolic 0.028
Vegfa vascular endothelial growth factor A 0.020
Mtus1 mitochondrial tumor suppressor 1 0.020
Il6r interleukin 6 receptor 0.019
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.017
Dnm1l dynamin 1-like 0.017
Fgf9 fibroblast growth factor 9 0.016
Cyb5r1 cytochrome b5 reductase 1 0.016
Snrk SNF related kinase 0.016
Rab3a RAB3A, member RAS oncogene family 0.015
Arf1 ADP-ribosylation factor 1 0.014
Jun Jun oncogene 0.013
Snurf SNRPN upstream reading frame 0.013
Slc4a3 solute carrier family 4 (anion exchanger), member 3 0.013
Vdac1 voltage-dependent anion channel 1 0.013
Klc2 kinesin light chain 2 0.012
Hsf1 heat shock transcription factor 1 0.012
Ogn osteoglycin 0.012
Ndrg4 N-myc downstream regulated gene 4 0.011
Hras Harvey rat sarcoma virus oncogene 0.011
Kitlg KIT ligand 0.011
Cdk5 cyclin-dependent kinase 5 0.011
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ASK1 Ask1p 1.000
DUO1 Duo1p 0.988
DAM1 Dam1p 0.984
SPC34 Spc34p 0.975
DAD4 Dad4p 0.951
DAD2 Dad2p 0.932
DAD1 Dad1p 0.907
HSK3 Hsk3p 0.696
SPC19 Spc19p 0.601
DAD3 Dad3p 0.181
MDS3 Mds3p 0.083
KAR9 Kar9p 0.031
STU2 Stu2p 0.029
AKL1 Akl1p 0.027
BIM1 Bim1p 0.026
DSN1 Dsn1p 0.022
ARP10 Arp10p 0.022
FPK1 Fpk1p 0.021
PCL9 Pcl9p 0.019
SRD1 Srd1p 0.017
LEU2 Leu2p 0.015
YLR162W hypothetical protein 0.015
PRP28 Prp28p 0.015
YOL038C-A hypothetical protein 0.014
YIR035C hypothetical protein 0.014
YLR264C-A hypothetical protein 0.014
YIR014W hypothetical protein 0.013
ARG8 Arg8p 0.013
HOT1 Hot1p 0.012
TAF8 Taf8p 0.012
MER1 Mer1p 0.012
MF(ALPHA)2 Mf(alpha)2p 0.012
PRS2 Prs2p 0.012
HPF1 Hpf1p 0.012
CBF2 Cbf2p 0.012
YAR068W hypothetical protein 0.011
YLR132C hypothetical protein 0.010
CRP1 Crp1p 0.010
YBR235W hypothetical protein 0.010
ALT2 Alt2p 0.010
MF(ALPHA)1 Mf(alpha)1p 0.010
KIP2 Kip2p 0.010
URA3 Ura3p 0.010