The network for 'tripartite regional subdivision' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

tripartite regional subdivision

Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.

Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
OCRL oculocerebrorenal syndrome of Lowe 0.978
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.971
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.898
SNAP25 synaptosomal-associated protein, 25kDa 0.830
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.828
ANAPC1 anaphase promoting complex subunit 1 0.809
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.791
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.773
GDA guanine deaminase 0.768
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.718
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.703
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.684
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.664
CUL2 cullin 2 0.657
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.656
EDC3 enhancer of mRNA decapping 3 homolog (S. cerevisiae) 0.581
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.571
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.531
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 0.512
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.497
MAPK1 mitogen-activated protein kinase 1 0.486
RFWD2 ring finger and WD repeat domain 2 0.464
NXF1 nuclear RNA export factor 1 0.453
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.450
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.449
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.426
ADAM17 ADAM metallopeptidase domain 17 0.425
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.422
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.410
CHRD chordin 0.387
STRADA STE20-related kinase adaptor alpha 0.377
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.354
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.349
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.340
KEAP1 kelch-like ECH-associated protein 1 0.335
SCHIP1 schwannomin interacting protein 1 0.332
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.320
FGFR1 fibroblast growth factor receptor 1 0.307
COMMD1 copper metabolism (Murr1) domain containing 1 0.300
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.300
TNIP2 TNFAIP3 interacting protein 2 0.293
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.284
PBK PDZ binding kinase 0.282
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.279
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.268
DLG4 discs, large homolog 4 (Drosophila) 0.267
LIN9 lin-9 homolog (C. elegans) 0.265
RHOA ras homolog gene family, member A 0.265
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.255
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.254
CUL1 cullin 1 0.246
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.243
HSPA8 heat shock 70kDa protein 8 0.241
SRSF1 serine/arginine-rich splicing factor 1 0.237
EZR ezrin 0.233
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.231
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.222
SORBS3 sorbin and SH3 domain containing 3 0.220
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.219
YBX1 Y box binding protein 1 0.214
MAP2K1 mitogen-activated protein kinase kinase 1 0.210
BMP1 bone morphogenetic protein 1 0.210
SRSF2 serine/arginine-rich splicing factor 2 0.210
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.200
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.196
PRKCZ protein kinase C, zeta 0.195
TACC3 transforming, acidic coiled-coil containing protein 3 0.188
DAXX death-domain associated protein 0.183
ACTN1 actinin, alpha 1 0.180
PRKCI protein kinase C, iota 0.173
CAB39 calcium binding protein 39 0.169
APC adenomatous polyposis coli 0.168
AKAP11 A kinase (PRKA) anchor protein 11 0.167
SDSL serine dehydratase-like 0.155
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.152
TRA2B transformer 2 beta homolog (Drosophila) 0.150
LARP1 La ribonucleoprotein domain family, member 1 0.149
JMJD6 jumonji domain containing 6 0.143
ZHX1 zinc fingers and homeoboxes 1 0.143
WDR83 WD repeat domain 83 0.140
SRSF9 serine/arginine-rich splicing factor 9 0.136
WNT3A wingless-type MMTV integration site family, member 3A 0.136
ANAPC7 anaphase promoting complex subunit 7 0.134
FBF1 Fas (TNFRSF6) binding factor 1 0.133
MAPK14 mitogen-activated protein kinase 14 0.132
VHL von Hippel-Lindau tumor suppressor 0.132
PRKCE protein kinase C, epsilon 0.131
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.130
CDC16 cell division cycle 16 homolog (S. cerevisiae) 0.128
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.127
GSK3B glycogen synthase kinase 3 beta 0.126
CDC34 cell division cycle 34 homolog (S. cerevisiae) 0.124
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.123
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.120
RANBP2 RAN binding protein 2 0.120
FZD1 frizzled homolog 1 (Drosophila) 0.119
TACC1 transforming, acidic coiled-coil containing protein 1 0.115
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.114
FUNDC2 FUN14 domain containing 2 0.114
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.071
snr-4 Protein SNR-4 0.065
wrm-1 Protein WRM-1 0.054
par-2 Protein PAR-2 0.035
lin-45 Protein LIN-45 0.025
cul-2 Protein CUL-2 0.024
glh-1 Protein GLH-1 0.023
zer-1 Protein ZER-1 0.020
mcm-2 Protein MCM-2 0.019
egl-46 Protein EGL-46 0.017
rars-1 Protein RARS-1 0.017
ceh-20 Protein CEH-20 0.016
dpy-22 Protein DPY-22 0.015
pgl-1 Protein PGL-1 0.013
tra-1 Protein TRA-1 0.013
ina-1 Protein INA-1 0.012
chk-1 Protein CHK-1 0.011
goa-1 Protein GOA-1 0.011
D1081.7 Protein D1081.7 0.011
hlh-30 Protein HLH-30 0.010
ztf-22 Protein ZTF-22 0.010
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Danio rerio
Name Description Probability Func Analog Organism
nanos3 nanos homolog 3 0.245
ndr2 nodal-related 2 0.135
dharma dharma 0.100
dazl daz-like gene 0.091
elavl2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) 0.068
ca15b carbonic anhydrase XV b 0.061
lft1 lefty1 0.061
piwil1 piwi-like 1 (Drosophila) 0.051
tbx16 T-box gene 16 0.049
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.045
aplnrb apelin receptor b 0.042
spaw southpaw 0.041
org oogenesis-related gene 0.036
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.029
runx1 runt-related transcription factor 1 0.027
etv2 ets variant gene 2 0.026
brca2 breast cancer 2, early onset 0.025
piwil2 piwi-like 2 (Drosophila) 0.023
bmp4 bone morphogenetic protein 4 0.021
znf711 zinc finger protein 711 0.021
tmem88a transmembrane protein 88 a 0.020
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.018
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.017
dlg2 discs, large (Drosophila) homolog 2 0.013
prkcz protein kinase C, zeta 0.013
axin1 axin 1 0.012
ntla no tail a 0.012
smx5 smx5 0.012
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.012
eif1axb eukaryotic translation initiation factor 1A, X-linked, b 0.012
brd2a bromodomain-containing 2a 0.011
mef2cb myocyte enhancer factor 2cb 0.011
klf4 Kruppel-like factor 4 0.011
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.011
srsf2 serine/arginine-rich splicing factor 2 0.010
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.010
cadps2 Ca2+-dependent activator protein for secretion 2 0.010
cdc42 cell division cycle 42 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
baz bazooka 0.996
aPKC atypical protein kinase C 0.988
stau staufen 0.976
par-1 CG8201 gene product from transcript CG8201-RA 0.965
sqd squid 0.954
aret arrest 0.951
psq pipsqueak 0.947
brat brain tumor 0.940
spir spire 0.927
Hel25E Helicase at 25E 0.917
tral trailer hitch 0.909
Dcp1 Decapping protein 1 0.889
sec5 CG8843 gene product from transcript CG8843-RA 0.887
shg shotgun 0.871
osk oskar 0.853
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.829
TER94 CG2331 gene product from transcript CG2331-RA 0.826
sax saxophone 0.813
ecd ecdysoneless 0.802
bcd bicoid 0.791
CG6854 CG6854 gene product from transcript CG6854-RC 0.747
par-6 CG5884 gene product from transcript CG5884-RA 0.713
pum pumilio 0.703
pita CG3941 gene product from transcript CG3941-RA 0.697
ksr kinase suppressor of ras 0.696
hb hunchback 0.692
Dlic Dynein light intermediate chain 0.678
didum dilute class unconventional myosin 0.631
Rac1 CG2248 gene product from transcript CG2248-RA 0.617
me31B maternal expression at 31B 0.605
fs(1)M3 female sterile (1) M3 0.591
spen split ends 0.585
Dad Daughters against dpp 0.541
mago mago nashi 0.537
ttk tramtrack 0.520
Lis-1 Lissencephaly-1 0.511
Eip75B Ecdysone-induced protein 75B 0.467
lola longitudinals lacking 0.463
vls valois 0.432
bic bicaudal 0.420
tud tudor 0.411
eya eyes absent 0.404
crb crumbs 0.401
Src64B Src oncogene at 64B 0.401
spn-E spindle E 0.400
tkv thickveins 0.390
Dp DP transcription factor 0.370
spn-F CG12114 gene product from transcript CG12114-RA 0.364
arm armadillo 0.361
CG11188 CG11188 gene product from transcript CG11188-RA 0.348
lilli lilliputian 0.341
fog folded gastrulation 0.341
BicD Bicaudal D 0.336
EcR Ecdysone receptor 0.331
NetB Netrin-B 0.330
Lam Lamin 0.316
mirr mirror 0.310
rok Rho-kinase 0.286
tsu tsunagi 0.279
CG10260 CG10260 gene product from transcript CG10260-RB 0.278
argos CG4531 gene product from transcript CG4531-RA 0.275
cta concertina 0.273
ens ensconsin 0.273
grk gurken 0.272
Nrx-IV Neurexin IV 0.271
Ras64B Ras oncogene at 64B 0.263
stnA stoned A 0.261
glo glorund 0.261
shn schnurri 0.260
Trl Trithorax-like 0.254
Dhc64C Dynein heavy chain 64C 0.248
cnc cap-n-collar 0.240
Mef2 Myocyte enhancer factor 2 0.238
kug kugelei 0.236
dpp decapentaplegic 0.236
dally division abnormally delayed 0.235
shot short stop 0.234
sim single-minded 0.233
caz cabeza 0.231
RpL10Ab Ribosomal protein L10Ab 0.231
Ser Serrate 0.227
CG34449 CG34449 gene product from transcript CG34449-RB 0.227
hyd hyperplastic discs 0.223
LanA Laminin A 0.223
vas vasa 0.223
Myd88 CG2078 gene product from transcript CG2078-RA 0.215
CycG Cyclin G 0.214
ci cubitus interruptus 0.211
csul capsuleen 0.211
swa swallow 0.210
orb oo18 RNA-binding protein 0.208
trk trunk 0.206
trc tricornered 0.198
retn retained 0.194
lic licorne 0.191
Fak56D Focal Adhesion Kinase 0.189
ftz-f1 ftz transcription factor 1 0.186
Kr Kruppel 0.183
slmb supernumerary limbs 0.182
CG4771 CG4771 gene product from transcript CG4771-RA 0.181
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Mus musculus
Name Description Probability Func Analog Organism
Nodal nodal 0.873
Ctnnb1 catenin (cadherin associated protein), beta 1 0.829
Lhx1 LIM homeobox protein 1 0.775
Fgf8 fibroblast growth factor 8 0.533
Pax2 paired box gene 2 0.505
Pitx2 paired-like homeodomain transcription factor 2 0.495
Apc adenomatosis polyposis coli 0.442
Shh sonic hedgehog 0.378
Gata4 GATA binding protein 4 0.357
Bmpr1a bone morphogenetic protein receptor, type 1A 0.351
Smad4 MAD homolog 4 (Drosophila) 0.285
Snap25 synaptosomal-associated protein 25 0.265
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.225
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.207
Fgfr2 fibroblast growth factor receptor 2 0.194
Otx2 orthodenticle homolog 2 (Drosophila) 0.187
Fgfr1 fibroblast growth factor receptor 1 0.176
Tgfb2 transforming growth factor, beta 2 0.146
Gli2 GLI-Kruppel family member GLI2 0.145
Emx2 empty spiracles homolog 2 (Drosophila) 0.136
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.134
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.132
Nog noggin 0.128
Gli3 GLI-Kruppel family member GLI3 0.127
Rarg retinoic acid receptor, gamma 0.124
Htt huntingtin 0.122
Lef1 lymphoid enhancer binding factor 1 0.122
Tbx1 T-box 1 0.118
Phox2a paired-like homeobox 2a 0.118
Ret ret proto-oncogene 0.115
Foxh1 forkhead box H1 0.100
Rxra retinoid X receptor alpha 0.087
Nf1 neurofibromatosis 1 0.087
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.080
Dok1 docking protein 1 0.076
Gsk3b glycogen synthase kinase 3 beta 0.074
Sox9 SRY-box containing gene 9 0.073
Foxc1 forkhead box C1 0.073
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.071
Rarb retinoic acid receptor, beta 0.071
Smad3 MAD homolog 3 (Drosophila) 0.070
Rara retinoic acid receptor, alpha 0.064
Inpp5d inositol polyphosphate-5-phosphatase D 0.064
Lhx9 LIM homeobox protein 9 0.061
Dok2 docking protein 2 0.060
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.059
Grb2 growth factor receptor bound protein 2 0.053
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.052
Arc activity regulated cytoskeletal-associated protein 0.047
Ank1 ankyrin 1, erythroid 0.045
Gdnf glial cell line derived neurotrophic factor 0.044
Fzd1 frizzled homolog 1 (Drosophila) 0.043
Wnt4 wingless-related MMTV integration site 4 0.042
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.040
Vav1 vav 1 oncogene 0.040
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.038
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.038
Pitx1 paired-like homeodomain transcription factor 1 0.036
Ece1 endothelin converting enzyme 1 0.036
Ctnnd1 catenin (cadherin associated protein), delta 1 0.034
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.033
Egr1 early growth response 1 0.032
Vegfa vascular endothelial growth factor A 0.032
Efnb2 ephrin B2 0.032
Ccnd1 cyclin D1 0.031
Fgf10 fibroblast growth factor 10 0.031
Fus fusion, derived from t(12;16) malignant liposarcoma (human) 0.030
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.030
Zic3 zinc finger protein of the cerebellum 3 0.029
Ncoa2 nuclear receptor coactivator 2 0.028
Smad1 MAD homolog 1 (Drosophila) 0.027
Drd2 dopamine receptor D2 0.027
Hoxa1 homeobox A1 0.027
Ikzf1 IKAROS family zinc finger 1 0.027
Ntf3 neurotrophin 3 0.027
Fzd8 frizzled homolog 8 (Drosophila) 0.027
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.026
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.026
Tcf7 transcription factor 7, T-cell specific 0.026
Amhr2 anti-Mullerian hormone type 2 receptor 0.026
Dlg1 discs, large homolog 1 (Drosophila) 0.025
Gata5 GATA binding protein 5 0.025
Col4a3 collagen, type IV, alpha 3 0.024
Smo smoothened homolog (Drosophila) 0.024
Wnt6 wingless-related MMTV integration site 6 0.024
Smad2 MAD homolog 2 (Drosophila) 0.024
Ina internexin neuronal intermediate filament protein, alpha 0.024
En1 engrailed 1 0.023
Smad6 MAD homolog 6 (Drosophila) 0.023
Bicd2 bicaudal D homolog 2 (Drosophila) 0.023
Axin1 axin 1 0.022
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.021
Gata6 GATA binding protein 6 0.021
Gdf1 growth differentiation factor 1 0.021
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.021
Ptk7 PTK7 protein tyrosine kinase 7 0.020
Hspa8 heat shock protein 8 0.019
Trp53 transformation related protein 53 0.019
Stat3 signal transducer and activator of transcription 3 0.019
Dnahc11 dynein, axonemal, heavy chain 11 0.019
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism