The network for 'regulation of canonical wnt signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of canonical wnt signaling pathway

Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.

Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Vangl2 vang-like 2 (van gogh, Drosophila) 1.000
Pten phosphatase and tensin homolog 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.999
Gli3 GLI-Kruppel family member GLI3 0.998
Pitx1 paired-like homeodomain transcription factor 1 0.997
Apc adenomatosis polyposis coli 0.996
Shh sonic hedgehog 0.996
Tbx3 T-box 3 0.991
Sox9 SRY-box containing gene 9 0.986
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.985
Wnt5a wingless-related MMTV integration site 5A 0.982
Pax3 paired box gene 3 0.978
Fgf10 fibroblast growth factor 10 0.973
Wnt3a wingless-related MMTV integration site 3A 0.972
Pax2 paired box gene 2 0.955
Pax8 paired box gene 8 0.945
Mapk14 mitogen-activated protein kinase 14 0.945
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.941
Meox2 mesenchyme homeobox 2 0.927
Alx4 aristaless-like homeobox 4 0.927
Bmp4 bone morphogenetic protein 4 0.905
Lmx1b LIM homeobox transcription factor 1 beta 0.902
Twist2 twist homolog 2 (Drosophila) 0.886
Emx2 empty spiracles homolog 2 (Drosophila) 0.886
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.885
Sox11 SRY-box containing gene 11 0.863
Fgf8 fibroblast growth factor 8 0.849
Foxc2 forkhead box C2 0.840
Ntf3 neurotrophin 3 0.835
Hand2 heart and neural crest derivatives expressed transcript 2 0.832
Smo smoothened homolog (Drosophila) 0.828
Gli2 GLI-Kruppel family member GLI2 0.827
Atf2 activating transcription factor 2 0.826
Bmpr1a bone morphogenetic protein receptor, type 1A 0.824
Lef1 lymphoid enhancer binding factor 1 0.821
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.807
Foxc1 forkhead box C1 0.801
Sfrp2 secreted frizzled-related protein 2 0.784
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.777
Sox2 SRY-box containing gene 2 0.775
Otx2 orthodenticle homolog 2 (Drosophila) 0.765
Gdnf glial cell line derived neurotrophic factor 0.764
Prrx1 paired related homeobox 1 0.761
Hand1 heart and neural crest derivatives expressed transcript 1 0.760
Ahr aryl-hydrocarbon receptor 0.756
Ar androgen receptor 0.737
Ret ret proto-oncogene 0.724
Sall4 sal-like 4 (Drosophila) 0.715
Wnt6 wingless-related MMTV integration site 6 0.706
Msx2 homeobox, msh-like 2 0.703
Il6st interleukin 6 signal transducer 0.697
Kitl kit ligand 0.696
Adam17 a disintegrin and metallopeptidase domain 17 0.695
Hif1a hypoxia inducible factor 1, alpha subunit 0.690
Hoxa1 homeobox A1 0.681
Nodal nodal 0.647
Clock circadian locomotor output cycles kaput 0.645
Fgfr1 fibroblast growth factor receptor 1 0.630
Trp53 transformation related protein 53 0.628
Pax6 paired box gene 6 0.625
Gata3 GATA binding protein 3 0.616
Vangl1 vang-like 1 (van gogh, Drosophila) 0.616
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.614
Hoxa13 homeobox A13 0.607
Jag1 jagged 1 0.605
Pou3f3 POU domain, class 3, transcription factor 3 0.605
Wt1 Wilms tumor 1 homolog 0.604
Gsk3b glycogen synthase kinase 3 beta 0.603
Hoxd13 homeobox D13 0.602
Lhx3 LIM homeobox protein 3 0.600
Esr1 estrogen receptor 1 (alpha) 0.592
Rarb retinoic acid receptor, beta 0.587
Gli1 GLI-Kruppel family member GLI1 0.581
Dlg1 discs, large homolog 1 (Drosophila) 0.574
Lrp6 low density lipoprotein receptor-related protein 6 0.566
Wnt4 wingless-related MMTV integration site 4 0.566
Wwtr1 WW domain containing transcription regulator 1 0.555
Ptk7 PTK7 protein tyrosine kinase 7 0.554
T brachyury 0.553
Bdnf brain derived neurotrophic factor 0.551
Pthlh parathyroid hormone-like peptide 0.548
Msx1 homeobox, msh-like 1 0.541
Foxa2 forkhead box A2 0.540
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.537
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.533
Dact3 dapper homolog 3, antagonist of beta-catenin (xenopus) 0.510
Smad6 MAD homolog 6 (Drosophila) 0.508
Dlx1 distal-less homeobox 1 0.502
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.497
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.487
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.478
Hoxa11 homeobox A11 0.473
Gas1 growth arrest specific 1 0.471
Eya1 eyes absent 1 homolog (Drosophila) 0.467
Gata4 GATA binding protein 4 0.465
Per2 period homolog 2 (Drosophila) 0.443
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.437
Zeb1 zinc finger E-box binding homeobox 1 0.435
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
let-60 Protein LET-60 0.164
egl-18 Protein EGL-18 0.142
F10G8.8 Protein F10G8.8 0.063
bar-1 Protein BAR-1 0.061
eor-1 Protein EOR-1 0.055
unc-5 Protein UNC-5 0.050
hmr-1 Protein HMR-1 0.048
pry-1 Protein PRY-1 0.047
sel-8 Protein SEL-8 0.042
dpy-22 Protein DPY-22 0.041
elc-1 Protein ELC-1 0.039
glp-1 Protein GLP-1 0.037
kal-1 Protein KAL-1 0.036
lin-36 Protein LIN-36 0.036
trim-9 Protein TRIM-9 0.035
ncx-3 Protein NCX-3 0.035
EGAP2.1 Protein EGAP2.1 0.035
gsk-3 Protein GSK-3 0.034
ten-1 Protein TEN-1 0.034
hid-1 Protein HID-1 0.034
lag-2 Protein LAG-2 0.034
C36E6.2 Protein C36E6.2 0.034
gon-2 Protein GON-2 0.034
elt-6 Protein ELT-6 0.033
nhr-25 Protein NHR-25 0.033
apm-3 Protein APM-3 0.033
ptp-3 Protein PTP-3 0.033
lin-23 Protein LIN-23 0.032
CELE_C01G6.5 Protein C01G6.5 0.032
npp-7 Protein NPP-7 0.032
sma-6 Protein SMA-6 0.031
vang-1 Protein VANG-1 0.031
odr-3 Protein ODR-3 0.031
klp-18 Protein KLP-18 0.030
daf-2 Protein DAF-2 0.029
lin-17 Protein LIN-17 0.029
smp-1 Protein SMP-1 0.029
lin-25 Protein LIN-25 0.029
K09F5.6 Protein K09F5.6 0.028
zyg-8 Protein ZYG-8 0.028
axl-1 Protein AXL-1 0.028
hlh-1 Protein HLH-1 0.028
unc-40 Protein UNC-40 0.028
cki-2 Protein CKI-2 0.027
B0035.6 Protein B0035.6 0.027
clec-180 Protein CLEC-180 0.027
ykt-6 Protein YKT-6 0.027
madf-5 Protein MADF-5 0.027
CELE_T04H1.2 Protein T04H1.2 0.027
rme-4 Protein RME-4 0.027
mpk-1 Protein MPK-1 0.026
grd-2 Protein GRD-2 0.026
flt-1 Protein FLT-1 0.026
tam-1 Protein TAM-1 0.025
C43H6.4 Protein C43H6.4 0.025
grd-1 Protein GRD-1 0.025
kqt-1 Protein KQT-1 0.025
C48D1.1 Protein C48D1.1 0.025
sos-1 Protein SOS-1 0.024
wrm-1 Protein WRM-1 0.024
nhr-67 Protein NHR-67 0.024
cst-1 Protein CST-1 0.024
klc-2 Protein KLC-2 0.024
F22D3.6 Protein F22D3.6 0.024
F21D5.1 Protein F21D5.1 0.024
F28B3.1 Protein F28B3.1 0.024
ima-3 Protein IMA-3 0.024
ubq-1 Protein UBQ-1 0.024
inx-3 Protein INX-3 0.023
xpo-1 Protein XPO-1 0.023
ttr-50 Protein TTR-50 0.023
mig-38 Protein MIG-38 0.023
sli-1 Protein SLI-1 0.023
magi-1 Protein MAGI-1 0.023
F37B4.10 Protein F37B4.10 0.023
sel-12 Protein SEL-12 0.023
daf-3 Protein DAF-3 0.023
CELE_F47G4.4 Protein F47G4.4 0.023
pig-1 Protein PIG-1 0.023
H19M22.3 Protein H19M22.3 0.023
col-128 Protein COL-128 0.022
elpc-4 Protein ELPC-4 0.022
pqn-59 Protein PQN-59 0.022
Y54E5A.7 Protein Y54E5A.7 0.022
lin-12 Protein LIN-12 0.022
mps-2 Protein MPS-2 0.022
sem-5 Protein SEM-5 0.022
vab-8 Protein VAB-8 0.022
imp-1 Protein IMP-1 0.022
lis-1 Protein LIS-1 0.022
eor-2 Protein EOR-2 0.022
R05G6.10 Protein R05G6.10 0.022
B0205.9 Protein B0205.9 0.022
col-172 Protein COL-172 0.022
icp-1 Protein ICP-1 0.021
sur-2 Protein SUR-2 0.021
Y44E3A.6 Protein Y44E3A.6 0.021
plx-2 Protein PLX-2 0.021
ham-1 Protein HAM-1 0.021
ttyh-1 Protein TTYH-1 0.021
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Danio rerio
Name Description Probability Func Analog Organism
wnt5b wingless-type MMTV integration site family, member 5b 0.922
wnt3a wingless-type MMTV integration site family, member 3A 0.836
wnt4a wingless-type MMTV integration site family, member 4a 0.737
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.726
axin2 axin 2 (conductin, axil) 0.690
bmp4 bone morphogenetic protein 4 0.642
ephb4b eph receptor B4b 0.548
fzd7b frizzled homolog 7b 0.535
per3 period homolog 3 (Drosophila) 0.506
fzd7a frizzled homolog 7a 0.503
sfrp1a secreted frizzled-related protein 1a 0.460
fzd5 frizzled homolog 5 0.436
sox19b SRY-box containing gene 19b 0.411
sox19a SRY-box containing gene 19a 0.410
mib mind bomb 0.392
gli1 GLI-Kruppel family member 1 0.374
dlc deltaC 0.369
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.358
pcdh18b protocadherin 18b 0.338
flh floating head 0.317
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.315
osr1 odd-skipped related 1 (Drosophila) 0.301
mmp2 matrix metalloproteinase 2 0.298
lfng lunatic fringe homolog 0.292
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.286
sox11b SRY-box containing gene 11b 0.282
wnt11 wingless-type MMTV integration site family, member 11 0.274
epha4b eph receptor A4b 0.268
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.253
hs6st1a heparan sulfate 6-O-sulfotransferase 1a 0.244
tbx16 T-box gene 16 0.240
notch3 notch homolog 3 0.238
hoxb1a homeo box B1a 0.234
dusp6 dual specificity phosphatase 6 0.234
si:ch211-173o4.2 si:ch211-173o4.2 0.234
crb2a crumbs homolog 2a 0.233
crabp2b cellular retinoic acid binding protein 2, b 0.231
foxb1.2 forkhead box B1.2 0.224
amotl2a angiomotin like 2a 0.222
spry2 sprouty homolog 2 0.215
gsc goosecoid 0.207
scube2 signal peptide, CUB domain, EGF-like 2 0.205
pea3 ETS-domain transcription factor pea3 0.201
wnt1 wingless-type MMTV integration site family, member 1 0.200
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.191
ndr2 nodal-related 2 0.189
wnt7bb wingless-type MMTV integration site family, member 7Bb 0.186
siah2l seven in absentia homolog 2 (Drosophila)-like 0.184
gli2a GLI-Kruppel family member GLI2a 0.181
eomesa eomesodermin homolog a 0.176
oep one-eyed pinhead 0.175
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.174
met met proto-oncogene (hepatocyte growth factor receptor) 0.170
wnt3 wingless-type MMTV integration site family, member 3 0.168
bty bloodthirsty 0.159
sox3 SRY-box containing gene 3 0.155
col1a2 collagen, type I, alpha 2 0.155
celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.155
zgc:171495 zgc:171495 0.153
nkd1 naked cuticle homolog 1 (Drosophila) 0.151
dharma dharma 0.147
dscam Down syndrome cell adhesion molecule 0.145
nhsl1b NHS-like 1b 0.142
nkx6.2 NK6 transcription factor related, locus 2 0.140
hoxb1b homeo box B1b 0.136
her5 hairy-related 5 0.136
wnt10a wingless-type MMTV integration site family, member 10a 0.136
notch2 notch homolog 2 0.134
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.133
cdx4 caudal type homeo box transcription factor 4 0.130
dld deltaD 0.127
rarab retinoic acid receptor, alpha b 0.127
hs3st3b1a heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a 0.127
si:ch211-235f6.2 si:ch211-235f6.2 0.126
hs6st1b heparan sulfate 6-O-sulfotransferase 1b 0.125
brd4 bromodomain containing 4 0.122
dkk1b dickkopf 1b 0.122
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.121
nog1 noggin 1 0.119
sox2 SRY-box containing gene 2 0.117
smo smoothened homolog (Drosophila) 0.116
map2k4a mitogen-activated protein kinase kinase 4a 0.114
olig4 oligodendrocyte transcription factor 4 0.114
bmpr1ab bone morphogenetic protein receptor, type 1ab 0.112
ntla no tail a 0.111
vsx1 visual system homeobox 1 homolog, chx10-like 0.110
znf503 zinc finger protein 503 0.110
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.109
col1a1a collagen, type I, alpha 1a 0.109
zbtb4 zinc finger and BTB domain containing 4 0.107
wls wntless homolog (Drosophila) 0.106
prdm14 PR domain containing 14 0.104
nanos3 nanos homolog 3 0.103
crb3a crumbs homolog 3a 0.100
znf703 zinc finger protein 703 0.100
ighz2 immunoglobulin heavy constant zeta2 0.100
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.099
wnt8b wingless-type MMTV integration site family, member 8b 0.098
fn1 fibronectin 1 0.098
epha4a eph receptor A4a 0.096
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Drosophila melanogaster
Name Description Probability Func Analog Organism
wg wingless 0.915
fz frizzled 0.850
bai baiser 0.840
sbb scribbler 0.647
sd scalloped 0.541
Rbf Retinoblastoma-family protein 0.450
sfl sulfateless 0.438
ap apterous 0.420
eca eclair 0.414
vg vestigial 0.382
dsh dishevelled 0.343
hpo hippo 0.271
Ras85D Ras oncogene at 85D 0.268
ci cubitus interruptus 0.247
Ptp69D Protein tyrosine phosphatase 69D 0.243
pan pangolin 0.230
EndoGI Endonuclease G inhibitor 0.226
CG9053 CG9053 gene product from transcript CG9053-RA 0.217
Hs6st Heparan sulfate 6-O-sulfotransferase 0.206
bnl branchless 0.204
sno strawberry notch 0.200
gbb glass bottom boat 0.198
wts warts 0.166
stumps CG31317 gene product from transcript CG31317-RC 0.157
phl pole hole 0.142
nct nicastrin 0.132
ovo CG6824 gene product from transcript CG6824-RE 0.131
ago archipelago 0.121
if inflated 0.119
Tak1 TGF-beta activated kinase 1 0.119
Sulf1 Sulfated 0.116
Trh Tryptophan hydroxylase 0.114
polo CG12306 gene product from transcript CG12306-RA 0.114
eya eyes absent 0.114
jing CG9397 gene product from transcript CG9397-RI 0.111
dx deltex 0.106
Rac1 CG2248 gene product from transcript CG2248-RA 0.106
stck steamer duck 0.105
fs(1)N female sterile (1) Nasrat 0.102
bsk basket 0.097
CHOp24 CG3564 gene product from transcript CG3564-RA 0.096
mats mob as tumor suppressor 0.095
krz kurtz 0.085
numb CG3779 gene product from transcript CG3779-RB 0.079
shi shibire 0.077
Tsc1 CG6147 gene product from transcript CG6147-RA 0.072
Wnt2 Wnt oncogene analog 2 0.070
dlp dally-like 0.066
Mpk2 CG5475 gene product from transcript CG5475-RB 0.065
Orc6 Origin recognition complex subunit 6 0.062
rl rolled 0.062
Socs36E Suppressor of cytokine signaling at 36E 0.060
shn schnurri 0.056
Dcp-1 Death caspase-1 0.054
brm brahma 0.051
S6kII RPS6-protein kinase-II 0.050
yki yorkie 0.050
dally division abnormally delayed 0.048
Klp64D Kinesin-like protein at 64D 0.048
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.047
Akt1 CG4006 gene product from transcript CG4006-RA 0.043
Btk29A Btk family kinase at 29A 0.043
capt capulet 0.040
ex expanded 0.039
exu exuperantia 0.039
hbs hibris 0.039
RASSF8 CG5053 gene product from transcript CG5053-RA 0.038
bif bifocal 0.038
sqz squeeze 0.036
Su(H) Suppressor of Hairless 0.036
jar jaguar 0.035
orb oo18 RNA-binding protein 0.035
Cdk4 Cyclin-dependent kinase 4 0.035
Dcr-1 Dicer-1 0.034
CG5794 CG5794 gene product from transcript CG5794-RB 0.034
CG9867 CG9867 gene product from transcript CG9867-RA 0.033
toy twin of eyeless 0.033
CG32354 CG32354 gene product from transcript CG32354-RA 0.033
Mlf Myelodysplasia/myeloid leukemia factor 0.032
LIMK1 LIM-kinase1 0.031
Mi-2 CG8103 gene product from transcript CG8103-RA 0.031
CG3371 CG3371 gene product from transcript CG3371-RA 0.031
p38b CG7393 gene product from transcript CG7393-RA 0.031
Ubx Ultrabithorax 0.031
twi twist 0.031
E(z) Enhancer of zeste 0.030
fj four-jointed 0.030
unc-5 CG8166 gene product from transcript CG8166-RA 0.030
sti sticky 0.029
ds dachsous 0.029
l(2)05510 lethal (2) 05510 0.029
tsr twinstar 0.029
rst roughest 0.029
CG9573 CG9573 gene product from transcript CG9573-RA 0.028
Rac2 CG8556 gene product from transcript CG8556-RA 0.028
mib1 mind bomb 1 0.027
ssh slingshot 0.027
mol moladietz 0.027
insc inscuteable 0.026
shg shotgun 0.026
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Homo sapiens
Name Description Probability Func Analog Organism
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.000
SMAD3 SMAD family member 3 1.000
SMAD4 SMAD family member 4 1.000
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.998
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.992
SMAD7 SMAD family member 7 0.990
AXIN1 axin 1 0.985
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.983
SMAD1 SMAD family member 1 0.980
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.978
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.976
CREBBP CREB binding protein 0.974
APC adenomatous polyposis coli 0.973
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.957
AR androgen receptor 0.956
PSEN1 presenilin 1 0.953
CSNK1E casein kinase 1, epsilon 0.951
GSK3B glycogen synthase kinase 3 beta 0.943
COL1A1 collagen, type I, alpha 1 0.942
FGFR1 fibroblast growth factor receptor 1 0.934
CDK14 cyclin-dependent kinase 14 0.928
COL1A2 collagen, type I, alpha 2 0.924
CCNY cyclin Y 0.921
PPP6R1 protein phosphatase 6, regulatory subunit 1 0.912
FGF1 fibroblast growth factor 1 (acidic) 0.909
EGFR epidermal growth factor receptor 0.904
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.876
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.875
ZNF512B zinc finger protein 512B 0.864
GLIS2 GLIS family zinc finger 2 0.848
BMP7 bone morphogenetic protein 7 0.845
TCF4 transcription factor 4 0.832
COL3A1 collagen, type III, alpha 1 0.830
HDAC1 histone deacetylase 1 0.822
SMAD2 SMAD family member 2 0.819
CAV1 caveolin 1, caveolae protein, 22kDa 0.810
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.808
SKP1 S-phase kinase-associated protein 1 0.807
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.785
HIPK3 homeodomain interacting protein kinase 3 0.780
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.779
UBE3A ubiquitin protein ligase E3A 0.757
MARK3 MAP/microtubule affinity-regulating kinase 3 0.756
DDR2 discoidin domain receptor tyrosine kinase 2 0.754
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.754
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.753
ARHGAP1 Rho GTPase activating protein 1 0.731
YAP1 Yes-associated protein 1 0.719
XIAP X-linked inhibitor of apoptosis 0.715
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.710
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.704
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.700
COL5A2 collagen, type V, alpha 2 0.696
COL4A1 collagen, type IV, alpha 1 0.686
BMPR1A bone morphogenetic protein receptor, type IA 0.676
SP1 Sp1 transcription factor 0.663
SMAD5 SMAD family member 5 0.658
COL5A1 collagen, type V, alpha 1 0.649
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.648
FZD1 frizzled homolog 1 (Drosophila) 0.647
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.640
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.636
PAX3 paired box 3 0.604
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.601
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.592
PARVA parvin, alpha 0.592
TBX5 T-box 5 0.587
LRP6 low density lipoprotein receptor-related protein 6 0.583
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.583
FOXD3 forkhead box D3 0.573
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.572
SFRP1 secreted frizzled-related protein 1 0.560
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.553
BTRC beta-transducin repeat containing 0.539
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.533
JUN jun proto-oncogene 0.525
PTPRJ protein tyrosine phosphatase, receptor type, J 0.523
ERBB2IP erbb2 interacting protein 0.503
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.502
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.496
FNBP1 formin binding protein 1 0.478
SUFU suppressor of fused homolog (Drosophila) 0.464
ZFYVE9 zinc finger, FYVE domain containing 9 0.460
WNT3A wingless-type MMTV integration site family, member 3A 0.459
FSTL1 follistatin-like 1 0.452
SKI v-ski sarcoma viral oncogene homolog (avian) 0.443
GIPC1 GIPC PDZ domain containing family, member 1 0.436
DSP desmoplakin 0.435
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.430
BTBD2 BTB (POZ) domain containing 2 0.424
CAV2 caveolin 2 0.418
CSNK1A1 casein kinase 1, alpha 1 0.414
SH3RF1 SH3 domain containing ring finger 1 0.403
ESR1 estrogen receptor 1 0.403
WNT5A wingless-type MMTV integration site family, member 5A 0.402
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.400
TUBA1A tubulin, alpha 1a 0.389
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.380
ATXN1 ataxin 1 0.366
CDK6 cyclin-dependent kinase 6 0.362
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Rattus norvegicus
Name Description Probability Func Analog Organism
Col5a2 collagen, type V, alpha 2 0.519
Egr2 early growth response 2 0.268
Dchs1 dachsous 1 (Drosophila) 0.194
Col4a5 collagen, type IV, alpha 5 0.178
Fos FBJ osteosarcoma oncogene 0.144
Nfia nuclear factor I/A 0.141
Sox18 SRY (sex determining region Y)-box 18 0.136
Lum lumican 0.120
Golph3 golgi phosphoprotein 3 (coat-protein) 0.118
Nradd neurotrophin receptor associated death domain 0.114
Igfbp5 insulin-like growth factor binding protein 5 0.107
Shox2 short stature homeobox 2 0.107
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.094
Sox4 SRY (sex determining region Y)-box 4 0.084
Ccdc8 coiled-coil domain containing 8 0.084
Junb jun B proto-oncogene 0.082
Gpc3 glypican 3 0.075
Tcf3 transcription factor 3 0.073
Taok1 TAO kinase 1 0.072
Mgea5 meningioma expressed antigen 5 (hyaluronidase) 0.072
Itga1 integrin, alpha 1 0.071
Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.070
Sh2b1 SH2B adaptor protein 1 0.069
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.069
Col3a1 collagen, type III, alpha 1 0.069
Col12a1 collagen, type XII, alpha 1 0.068
Gfra1 GDNF family receptor alpha 1 0.067
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.066
Dock1 dedicator of cyto-kinesis 1 0.065
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.063
Bmp4 bone morphogenetic protein 4 0.062
Plagl1 pleiomorphic adenoma gene-like 1 0.062
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.061
RGD1564560 similar to RCK 0.060
St5 suppression of tumorigenicity 5 0.060
Stat3 signal transducer and activator of transcription 3 0.060
Ddah1 dimethylarginine dimethylaminohydrolase 1 0.059
Hoxd9 homeo box D9 0.058
Limd1 LIM domains containing 1 0.058
Capn6 calpain 6 0.058
Lamc1 laminin, gamma 1 0.058
Calcrl calcitonin receptor-like 0.057
Ggta1 glycoprotein, alpha-galactosyltransferase 1 0.057
Dusp6 dual specificity phosphatase 6 0.056
Dab2 disabled homolog 2 (Drosophila) 0.056
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.055
Mesdc2 mesoderm development candidate 2 0.055
Bmp1 bone morphogenetic protein 1 0.055
Dact1 dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) 0.054
Tcf4 transcription factor 4 0.053
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.052
Igf2r insulin-like growth factor 2 receptor 0.052
Pcdhb12 protocadherin beta 12 0.052
Pllp plasma membrane proteolipid (plasmolipin) 0.051
Klf2 Kruppel-like factor 2 (lung) 0.051
Afap1l2 actin filament associated protein 1-like 2 0.051
Sox13 SRY (sex determining region Y)-box 13 0.050
RGD1562618 similar to RIKEN cDNA 6030419C18 gene 0.049
Spon1 spondin 1, extracellular matrix protein 0.049
Jub jub, ajuba homolog (Xenopus laevis) 0.047
Dlg1 discs, large homolog 1 (Drosophila) 0.047
LOC100361765 homeobox B2 0.047
Adcy3 adenylate cyclase 3 0.046
Prkci protein kinase C, iota 0.046
Ltbp4 latent transforming growth factor beta binding protein 4 0.046
Reln reelin 0.046
Sstr1 somatostatin receptor 1 0.045
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 0.045
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.045
Dlx5 distal-less homeobox 5 0.045
Myo1b myosin Ib 0.044
Arvcf armadillo repeat gene deleted in velo-cardio-facial syndrome 0.044
Kifc3 kinesin family member C3 0.044
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.044
Tm9sf3 transmembrane 9 superfamily member 3 0.043
Dcn decorin 0.043
Ccdc3 coiled-coil domain containing 3 0.043
Adcy6 adenylate cyclase 6 0.043
Slit3 slit homolog 3 (Drosophila) 0.042
Tnni1 troponin I type 1 (skeletal, slow) 0.042
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.042
Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.041
Olfml2a olfactomedin-like 2A 0.041
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.041
Fat4 FAT tumor suppressor homolog 4 (Drosophila) 0.041
Prpf40a PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.041
Insr insulin receptor 0.041
Smc1a structural maintenance of chromosomes 1A 0.040
Fndc3b fibronectin type III domain containing 3B 0.040
Tcf12 transcription factor 12 0.040
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.040
Fat1 FAT tumor suppressor homolog 1 (Drosophila) 0.040
Synrg synergin, gamma 0.040
Kdm6b lysine (K)-specific demethylase 6B 0.040
Gpr116 G protein-coupled receptor 116 0.040
Ntf3 neurotrophin 3 0.039
LOC691920 similar to kinesin-like motor protein C20orf23 0.039
Myog myogenin 0.039
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.039
Mapk9 mitogen-activated protein kinase 9 0.039
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism