IMP
Process View
The network for 'vascular wound healing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
vascular wound healing
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 0.997 | |
| Bmp4 | bone morphogenetic protein 4 | 0.997 | |
| Foxc2 | forkhead box C2 | 0.996 | |
| Foxc1 | forkhead box C1 | 0.993 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.991 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.990 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.987 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.984 | |
| Tbx1 | T-box 1 | 0.984 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.984 | |
| Pax2 | paired box gene 2 | 0.969 | |
| Pax3 | paired box gene 3 | 0.968 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.964 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.960 | |
| Prrx1 | paired related homeobox 1 | 0.954 | |
| Sox9 | SRY-box containing gene 9 | 0.952 | |
| Msx1 | homeobox, msh-like 1 | 0.930 | |
| Fgf8 | fibroblast growth factor 8 | 0.925 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.904 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.904 | |
| Dlx5 | distal-less homeobox 5 | 0.873 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.856 | |
| Chrd | chordin | 0.848 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.808 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.767 | |
| Jag1 | jagged 1 | 0.761 | |
| Smo | smoothened homolog (Drosophila) | 0.741 | |
| Hoxa1 | homeobox A1 | 0.696 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.689 | |
| Ednra | endothelin receptor type A | 0.638 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.621 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.608 | |
| Gsc | goosecoid homeobox | 0.553 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.551 | |
| Efnb2 | ephrin B2 | 0.514 | |
| Prrx2 | paired related homeobox 2 | 0.497 | |
| Meox2 | mesenchyme homeobox 2 | 0.494 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.473 | |
| Bmp7 | bone morphogenetic protein 7 | 0.458 | |
| Msx2 | homeobox, msh-like 2 | 0.407 | |
| Hmx3 | H6 homeobox 3 | 0.401 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.396 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.388 | |
| Nog | noggin | 0.380 | |
| Rarb | retinoic acid receptor, beta | 0.354 | |
| En1 | engrailed 1 | 0.347 | |
| Pax9 | paired box gene 9 | 0.331 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.318 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.315 | |
| Vegfa | vascular endothelial growth factor A | 0.310 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.307 | |
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.287 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.283 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.269 | |
| Hoxa3 | homeobox A3 | 0.246 | |
| Runx2 | runt related transcription factor 2 | 0.245 | |
| Pax6 | paired box gene 6 | 0.226 | |
| Nkx3-2 | NK3 homeobox 2 | 0.222 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.207 | |
| Foxg1 | forkhead box G1 | 0.205 | |
| Nkx2-1 | NK2 homeobox 1 | 0.200 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.192 | |
| Sox2 | SRY-box containing gene 2 | 0.192 | |
| Hoxa2 | homeobox A2 | 0.185 | |
| Alx1 | ALX homeobox 1 | 0.175 | |
| Gata4 | GATA binding protein 4 | 0.174 | |
| Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.146 | |
| Hoxd3 | homeobox D3 | 0.123 | |
| Dlx2 | distal-less homeobox 2 | 0.119 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.116 | |
| T | brachyury | 0.115 | |
| Alx4 | aristaless-like homeobox 4 | 0.112 | |
| Psen1 | presenilin 1 | 0.108 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.104 | |
| Rarg | retinoic acid receptor, gamma | 0.098 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.096 | |
| Foxe3 | forkhead box E3 | 0.092 | |
| Acvr1 | activin A receptor, type 1 | 0.089 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.087 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.086 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.081 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.081 | |
| Foxb1 | forkhead box B1 | 0.081 | |
| Neurog1 | neurogenin 1 | 0.079 | |
| Fgf3 | fibroblast growth factor 3 | 0.074 | |
| Ece1 | endothelin converting enzyme 1 | 0.073 | |
| Mesp1 | mesoderm posterior 1 | 0.073 | |
| Bmp2 | bone morphogenetic protein 2 | 0.072 | |
| Lox | lysyl oxidase | 0.072 | |
| Pax1 | paired box gene 1 | 0.072 | |
| Ptch1 | patched homolog 1 | 0.071 | |
| Tbx15 | T-box 15 | 0.070 | |
| Vax1 | ventral anterior homeobox containing gene 1 | 0.069 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.068 | |
| Hmx1 | H6 homeobox 1 | 0.067 | |
| Sox3 | SRY-box containing gene 3 | 0.065 | |
| Ntf3 | neurotrophin 3 | 0.064 | |
| Matn3 | matrilin 3 | 0.062 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.061 | |
| Egfr | epidermal growth factor receptor | 0.061 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1.000 | |
| NRP1 | neuropilin 1 | 1.000 | |
| VEGFA | vascular endothelial growth factor A | 1.000 | |
| PLAU | plasminogen activator, urokinase | 1.000 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 1.000 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.999 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.999 | |
| PGF | placental growth factor | 0.992 | |
| COL4A1 | collagen, type IV, alpha 1 | 0.985 | |
| PLAT | plasminogen activator, tissue | 0.964 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.932 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.925 | |
| COL4A2 | collagen, type IV, alpha 2 | 0.822 | |
| COL5A1 | collagen, type V, alpha 1 | 0.759 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.718 | |
| PDGFC | platelet derived growth factor C | 0.703 | |
| COL6A1 | collagen, type VI, alpha 1 | 0.593 | |
| PLCG1 | phospholipase C, gamma 1 | 0.561 | |
| STC1 | stanniocalcin 1 | 0.499 | |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.476 | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.470 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.331 | |
| ENG | endoglin | 0.289 | |
| LAMA5 | laminin, alpha 5 | 0.288 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.268 | |
| COL1A1 | collagen, type I, alpha 1 | 0.266 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.219 | |
| THBS1 | thrombospondin 1 | 0.177 | |
| LDLR | low density lipoprotein receptor | 0.171 | |
| COL1A2 | collagen, type I, alpha 2 | 0.145 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.123 | |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.112 | |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.091 | |
| PXDN | peroxidasin homolog (Drosophila) | 0.086 | |
| VEGFC | vascular endothelial growth factor C | 0.081 | |
| COL16A1 | collagen, type XVI, alpha 1 | 0.077 | |
| ANGPTL4 | angiopoietin-like 4 | 0.075 | |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.074 | |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.071 | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.071 | |
| AES | amino-terminal enhancer of split | 0.065 | |
| ANGPT2 | angiopoietin 2 | 0.063 | |
| ORM1 | orosomucoid 1 | 0.056 | |
| COL2A1 | collagen, type II, alpha 1 | 0.055 | |
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.050 | |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.050 | |
| FZD4 | frizzled homolog 4 (Drosophila) | 0.050 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.048 | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.047 | |
| SPHK1 | sphingosine kinase 1 | 0.046 | |
| ROBO4 | roundabout homolog 4, magic roundabout (Drosophila) | 0.042 | |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.041 | |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.041 | |
| FOSL2 | FOS-like antigen 2 | 0.039 | |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.038 | |
| NRP2 | neuropilin 2 | 0.038 | |
| STC2 | stanniocalcin 2 | 0.036 | |
| JAG1 | jagged 1 | 0.036 | |
| FLT4 | fms-related tyrosine kinase 4 | 0.035 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.035 | |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.035 | |
| PALM | paralemmin | 0.033 | |
| COL3A1 | collagen, type III, alpha 1 | 0.032 | |
| MDFI | MyoD family inhibitor | 0.031 | |
| NNMT | nicotinamide N-methyltransferase | 0.029 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.029 | |
| FST | follistatin | 0.028 | |
| IER3 | immediate early response 3 | 0.027 | |
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.026 | |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.025 | |
| TGFB2 | transforming growth factor, beta 2 | 0.024 | |
| VWF | von Willebrand factor | 0.024 | |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.024 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.024 | |
| INHBA | inhibin, beta A | 0.023 | |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.022 | |
| TNC | tenascin C | 0.022 | |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.022 | |
| IL8 | interleukin 8 | 0.021 | |
| NOTCH3 | notch 3 | 0.021 | |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.021 | |
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.020 | |
| ANGPTL2 | angiopoietin-like 2 | 0.019 | |
| SRPX | sushi-repeat containing protein, X-linked | 0.019 | |
| TEK | TEK tyrosine kinase, endothelial | 0.018 | |
| BGN | biglycan | 0.018 | |
| CD248 | CD248 molecule, endosialin | 0.017 | |
| G0S2 | G0/G1switch 2 | 0.017 | |
| BMP4 | bone morphogenetic protein 4 | 0.017 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.017 | |
| NOTCH4 | notch 4 | 0.017 | |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.017 | |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.017 | |
| ESAM | endothelial cell adhesion molecule | 0.016 | |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.016 | |
| FADS3 | fatty acid desaturase 3 | 0.016 | |
| PVR | poliovirus receptor | 0.016 | |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.016 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.015 |