IMP
Process View
The network for 'fat cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
fat cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 0.981 | |
| Lepr | leptin receptor | 0.981 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.972 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.966 | |
| Bbs2 | Bardet-Biedl syndrome 2 (human) | 0.962 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.961 | |
| Jun | Jun oncogene | 0.960 | |
| Rxra | retinoid X receptor alpha | 0.946 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.938 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.932 | |
| Fgf10 | fibroblast growth factor 10 | 0.931 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.925 | |
| Bbs4 | Bardet-Biedl syndrome 4 (human) | 0.913 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.905 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.903 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.898 | |
| Per2 | period homolog 2 (Drosophila) | 0.883 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.882 | |
| Fos | FBJ osteosarcoma oncogene | 0.872 | |
| Dusp1 | dual specificity phosphatase 1 | 0.870 | |
| Pthlh | parathyroid hormone-like peptide | 0.855 | |
| Dll1 | delta-like 1 (Drosophila) | 0.839 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.838 | |
| Klf4 | Kruppel-like factor 4 (gut) | 0.828 | |
| Clock | circadian locomotor output cycles kaput | 0.827 | |
| Hoxd13 | homeobox D13 | 0.827 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.820 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.802 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.800 | |
| Msx1 | homeobox, msh-like 1 | 0.782 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.777 | |
| Alx4 | aristaless-like homeobox 4 | 0.775 | |
| Sfrp2 | secreted frizzled-related protein 2 | 0.770 | |
| Hoxa13 | homeobox A13 | 0.769 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.769 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.764 | |
| Rarg | retinoic acid receptor, gamma | 0.759 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.753 | |
| Smad7 | MAD homolog 7 (Drosophila) | 0.751 | |
| Thra | thyroid hormone receptor alpha | 0.743 | |
| Tcf4 | transcription factor 4 | 0.736 | |
| Sox2 | SRY-box containing gene 2 | 0.733 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.726 | |
| Foxf1a | forkhead box F1a | 0.723 | |
| Tcf21 | transcription factor 21 | 0.720 | |
| Hr | hairless | 0.716 | |
| Crb2 | crumbs homolog 2 (Drosophila) | 0.714 | |
| Plin1 | perilipin 1 | 0.707 | |
| Prrx2 | paired related homeobox 2 | 0.699 | |
| Nf1 | neurofibromatosis 1 | 0.696 | |
| Timp2 | tissue inhibitor of metalloproteinase 2 | 0.691 | |
| Btbd17 | BTB (POZ) domain containing 17 | 0.687 | |
| Nog | noggin | 0.685 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.684 | |
| Cidec | cell death-inducing DFFA-like effector c | 0.684 | |
| Hic1 | hypermethylated in cancer 1 | 0.681 | |
| Cdk4 | cyclin-dependent kinase 4 | 0.676 | |
| Trp63 | transformation related protein 63 | 0.675 | |
| Insr | insulin receptor | 0.674 | |
| Vegfa | vascular endothelial growth factor A | 0.671 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.667 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.657 | |
| Egr1 | early growth response 1 | 0.652 | |
| Tbx3 | T-box 3 | 0.648 | |
| Prrx1 | paired related homeobox 1 | 0.647 | |
| Axin2 | axin2 | 0.633 | |
| Msx2 | homeobox, msh-like 2 | 0.630 | |
| Btg2 | B-cell translocation gene 2, anti-proliferative | 0.627 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.626 | |
| Cry2 | cryptochrome 2 (photolyase-like) | 0.625 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.624 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.623 | |
| Pax3 | paired box gene 3 | 0.618 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.607 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.602 | |
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.598 | |
| Mmp2 | matrix metallopeptidase 2 | 0.598 | |
| Rhob | ras homolog gene family, member B | 0.592 | |
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.591 | |
| Atf2 | activating transcription factor 2 | 0.588 | |
| Ahr | aryl-hydrocarbon receptor | 0.587 | |
| Apaf1 | apoptotic peptidase activating factor 1 | 0.584 | |
| Pax2 | paired box gene 2 | 0.584 | |
| Bmp4 | bone morphogenetic protein 4 | 0.582 | |
| C1qc | complement component 1, q subcomponent, C chain | 0.570 | |
| Tead3 | TEA domain family member 3 | 0.570 | |
| Id3 | inhibitor of DNA binding 3 | 0.565 | |
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.549 | |
| Gdf5 | growth differentiation factor 5 | 0.548 | |
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.536 | |
| Gata4 | GATA binding protein 4 | 0.533 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.529 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.529 | |
| Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.528 | |
| Col2a1 | collagen, type II, alpha 1 | 0.527 | |
| Yap1 | yes-associated protein 1 | 0.522 | |
| Klf2 | Kruppel-like factor 2 (lung) | 0.521 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.517 | |
| Pax8 | paired box gene 8 | 0.512 | |
| Fgf5 | fibroblast growth factor 5 | 0.510 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BBS10 | Bardet-Biedl syndrome 10 | 0.982 | |
| SMAD3 | SMAD family member 3 | 0.906 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.844 | |
| EP300 | E1A binding protein p300 | 0.785 | |
| TP53 | tumor protein p53 | 0.702 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.678 | |
| SMAD7 | SMAD family member 7 | 0.602 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.601 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.587 | |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.537 | |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.522 | |
| SMAD4 | SMAD family member 4 | 0.514 | |
| AR | androgen receptor | 0.497 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.488 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.408 | |
| BBS4 | Bardet-Biedl syndrome 4 | 0.390 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.380 | |
| CREBBP | CREB binding protein | 0.337 | |
| NCOA3 | nuclear receptor coactivator 3 | 0.334 | |
| SMAD1 | SMAD family member 1 | 0.321 | |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.314 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.270 | |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.264 | |
| STK3 | serine/threonine kinase 3 | 0.257 | |
| APP | amyloid beta (A4) precursor protein | 0.232 | |
| BBS2 | Bardet-Biedl syndrome 2 | 0.226 | |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.224 | |
| ATXN1 | ataxin 1 | 0.220 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.218 | |
| SP1 | Sp1 transcription factor | 0.211 | |
| PGR | progesterone receptor | 0.210 | |
| STAG2 | stromal antigen 2 | 0.201 | |
| BBS9 | Bardet-Biedl syndrome 9 | 0.173 | |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.170 | |
| NCF1 | neutrophil cytosolic factor 1 | 0.169 | |
| CSNK1E | casein kinase 1, epsilon | 0.167 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.159 | |
| NOTCH3 | notch 3 | 0.155 | |
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.142 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.125 | |
| BBS7 | Bardet-Biedl syndrome 7 | 0.120 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.114 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.110 | |
| STK4 | serine/threonine kinase 4 | 0.108 | |
| SQSTM1 | sequestosome 1 | 0.106 | |
| JUN | jun proto-oncogene | 0.105 | |
| CDK6 | cyclin-dependent kinase 6 | 0.093 | |
| DHCR7 | 7-dehydrocholesterol reductase | 0.090 | |
| GATA2 | GATA binding protein 2 | 0.088 | |
| AXIN1 | axin 1 | 0.087 | |
| APC | adenomatous polyposis coli | 0.084 | |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.081 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.076 | |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.070 | |
| ZFPM1 | zinc finger protein, multitype 1 | 0.068 | |
| SFRP1 | secreted frizzled-related protein 1 | 0.067 | |
| HMGA1 | high mobility group AT-hook 1 | 0.067 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.067 | |
| PRKCZ | protein kinase C, zeta | 0.066 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.064 | |
| FSTL1 | follistatin-like 1 | 0.061 | |
| SMAD5 | SMAD family member 5 | 0.060 | |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.059 | |
| EGR1 | early growth response 1 | 0.058 | |
| NOXA1 | NADPH oxidase activator 1 | 0.057 | |
| PTN | pleiotrophin | 0.056 | |
| GLIS2 | GLIS family zinc finger 2 | 0.055 | |
| PRKCA | protein kinase C, alpha | 0.055 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.050 | |
| TCF4 | transcription factor 4 | 0.050 | |
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.050 | |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.050 | |
| IRS1 | insulin receptor substrate 1 | 0.049 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.048 | |
| FZD7 | frizzled homolog 7 (Drosophila) | 0.047 | |
| ACACA | acetyl-CoA carboxylase alpha | 0.047 | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.047 | |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.045 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.045 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.043 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.042 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.039 | |
| FOXO3 | forkhead box O3 | 0.039 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.038 | |
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.038 | |
| ZNF148 | zinc finger protein 148 | 0.037 | |
| KCTD1 | potassium channel tetramerisation domain containing 1 | 0.036 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.036 | |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.036 | |
| ZHX1 | zinc fingers and homeoboxes 1 | 0.036 | |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.036 | |
| SAV1 | salvador homolog 1 (Drosophila) | 0.035 | |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.035 | |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.035 | |
| HIC1 | hypermethylated in cancer 1 | 0.034 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.034 | |
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.034 | |
| CLOCK | clock homolog (mouse) | 0.034 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.034 | |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.033 |