The network for 'positive regulation of ras gtpase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of ras gtpase activity

Any process that activates or increases the activity of a GTPase of the Ras superfamily.

Mus musculus
Name Description Probability Func Analog Organism
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.981
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.976
Dlg4 discs, large homolog 4 (Drosophila) 0.963
Nf1 neurofibromatosis 1 0.953
Grb2 growth factor receptor bound protein 2 0.947
Efnb2 ephrin B2 0.931
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.922
Rac1 RAS-related C3 botulinum substrate 1 0.917
Plxnb1 plexin B1 0.880
Tsc1 tuberous sclerosis 1 0.862
Epha4 Eph receptor A4 0.853
Braf Braf transforming gene 0.820
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.802
Pnpla2 patatin-like phospholipase domain containing 2 0.747
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.746
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.740
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.732
Lepr leptin receptor 0.713
Eps15 epidermal growth factor receptor pathway substrate 15 0.694
Plxna1 plexin A1 0.690
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.662
Ephb2 Eph receptor B2 0.657
Laptm5 lysosomal-associated protein transmembrane 5 0.654
Ntf3 neurotrophin 3 0.623
Kl klotho 0.623
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.601
Bcr breakpoint cluster region 0.560
Prkce protein kinase C, epsilon 0.554
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.540
Arrb2 arrestin, beta 2 0.509
Arhgap21 Rho GTPase activating protein 21 0.495
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.494
Ldb3 LIM domain binding 3 0.482
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.478
Ccl2 chemokine (C-C motif) ligand 2 0.478
Vav3 vav 3 oncogene 0.477
Selplg selectin, platelet (p-selectin) ligand 0.470
Rasgrp1 RAS guanyl releasing protein 1 0.459
Cbl Casitas B-lineage lymphoma 0.450
Rasal3 RAS protein activator like 3 0.439
Src Rous sarcoma oncogene 0.436
Vav2 vav 2 oncogene 0.426
Nf2 neurofibromatosis 2 0.422
Apc adenomatosis polyposis coli 0.416
Git1 G protein-coupled receptor kinase-interactor 1 0.402
Rtkn rhotekin 0.380
Plcg1 phospholipase C, gamma 1 0.380
Nckap1l NCK associated protein 1 like 0.374
Dnm1 dynamin 1 0.373
Mtap2 microtubule-associated protein 2 0.369
Sox10 SRY-box containing gene 10 0.364
Akt1 thymoma viral proto-oncogene 1 0.358
Adrbk1 adrenergic receptor kinase, beta 1 0.355
Pxn paxillin 0.343
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.339
Nrbp2 nuclear receptor binding protein 2 0.330
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.328
Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 0.324
Itga3 integrin alpha 3 0.320
Plcb1 phospholipase C, beta 1 0.319
Prkcc protein kinase C, gamma 0.318
Ctnnb1 catenin (cadherin associated protein), beta 1 0.315
Efna1 ephrin A1 0.311
Plxnd1 plexin D1 0.308
Arrb1 arrestin, beta 1 0.308
Vav1 vav 1 oncogene 0.291
Wnt7a wingless-related MMTV integration site 7A 0.287
Elmo1 engulfment and cell motility 1, ced-12 homolog (C. elegans) 0.282
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.279
Cd37 CD37 antigen 0.278
Grid1 glutamate receptor, ionotropic, delta 1 0.269
Ptprb protein tyrosine phosphatase, receptor type, B 0.268
Sh3kbp1 SH3-domain kinase binding protein 1 0.265
Iqsec1 IQ motif and Sec7 domain 1 0.265
Hdac7 histone deacetylase 7 0.265
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.253
Srgap2 SLIT-ROBO Rho GTPase activating protein 2 0.249
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 0.247
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.246
Sstr4 somatostatin receptor 4 0.245
Mmp15 matrix metallopeptidase 15 0.237
Nrp1 neuropilin 1 0.234
Epha1 Eph receptor A1 0.231
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.231
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.230
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.228
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.226
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.226
Tsc2 tuberous sclerosis 2 0.225
Abr active BCR-related gene 0.224
Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) 0.220
Lrrk2 leucine-rich repeat kinase 2 0.220
Tbx2 T-box 2 0.217
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.214
Mobp myelin-associated oligodendrocytic basic protein 0.211
Sipa1 signal-induced proliferation associated gene 1 0.207
Nrg1 neuregulin 1 0.207
Kcnk2 potassium channel, subfamily K, member 2 0.204
Fnbp1 formin binding protein 1 0.202
Ptpre protein tyrosine phosphatase, receptor type, E 0.201
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
let-60 Protein LET-60 0.282
unc-94 Protein UNC-94 0.202
smp-1 Protein SMP-1 0.172
pqe-1 Protein PQE-1 0.163
rme-4 Protein RME-4 0.154
gei-4 Protein GEI-4 0.132
lag-1 Protein LAG-1 0.110
unc-71 Protein UNC-71 0.099
F52G3.1 Protein F52G3.1 0.091
CELE_W07A8.2 Protein W07A8.2 0.085
sem-5 Protein SEM-5 0.081
itr-1 Protein ITR-1 0.081
snf-1 Protein SNF-1 0.078
CELE_F47G4.4 Protein F47G4.4 0.066
afd-1 Protein AFD-1 0.064
eor-1 Protein EOR-1 0.062
C11E4.6 Protein C11E4.6 0.061
ptp-1 Protein PTP-1 0.058
F22D3.2 Protein F22D3.2 0.054
set-16 Protein SET-16 0.053
efa-6 Protein EFA-6 0.052
egrh-1 Protein EGRH-1 0.052
ark-1 Protein ARK-1 0.046
flt-1 Protein FLT-1 0.044
T28B11.1 Protein T28B11.1 0.044
pat-3 Protein PAT-3 0.041
fzr-1 Protein FZR-1 0.041
C06G1.5 Protein C06G1.5 0.040
rfc-1 Protein RFC-1 0.039
sax-3 Protein SAX-3 0.039
sam-10 Protein SAM-10 0.036
elt-6 Protein ELT-6 0.036
plc-3 Protein PLC-3 0.035
rig-6 Protein RIG-6 0.035
par-3 Protein PAR-3 0.033
Y87G2A.1 Protein Y87G2A.1 0.033
ttm-2 Protein TTM-2 0.031
gap-2 Protein GAP-2 0.031
T28H10.3 Protein T28H10.3 0.030
cyld-1 Protein CYLD-1 0.030
zfp-1 Protein ZFP-1 0.030
unc-15 Protein UNC-15 0.030
unc-26 Protein UNC-26 0.030
lir-1 Protein LIR-1 0.029
cdh-9 Protein CDH-9 0.028
CELE_K08E7.6 Protein K08E7.6 0.028
pdk-1 Protein PDK-1 0.027
stau-1 Protein STAU-1 0.027
sup-17 Protein SUP-17 0.026
rab-35 Protein RAB-35 0.026
lat-1 Protein LAT-1 0.026
CELE_F53C11.5 Protein F53C11.5 0.026
F29G6.2 Protein F29G6.2 0.026
larp-5 Protein LARP-5 0.026
asd-1 Protein ASD-1 0.026
unc-115 Protein UNC-115 0.025
eor-2 Protein EOR-2 0.025
mtm-3 Protein MTM-3 0.025
F35G2.1 Protein F35G2.1 0.024
gck-2 Protein GCK-2 0.024
F26H9.2 Protein F26H9.2 0.024
exc-5 Protein EXC-5 0.024
frm-10 Protein FRM-10 0.023
inft-2 Protein INFT-2 0.023
gar-3 Protein GAR-3 0.023
magi-1 Protein MAGI-1 0.022
ddr-2 Protein DDR-2 0.022
sel-8 Protein SEL-8 0.022
inx-1 Protein INX-1 0.022
smg-8 Protein SMG-8 0.021
mpk-1 Protein MPK-1 0.021
exp-2 Protein EXP-2 0.020
cnt-2 Protein CNT-2 0.020
B0511.12 Protein B0511.12 0.020
cah-6 Protein CAH-6 0.019
ztf-20 Protein ZTF-20 0.019
R11A8.7 Protein R11A8.7 0.019
D2096.11 Protein D2096.11 0.019
pry-1 Protein PRY-1 0.019
D1044.6 Protein D1044.6 0.018
tmc-2 Protein TMC-2 0.018
rgl-1 Protein RGL-1 0.018
frm-3 Protein FRM-3 0.018
npp-7 Protein NPP-7 0.018
sma-6 Protein SMA-6 0.018
rhgf-2 Protein RHGF-2 0.017
rsd-6 Protein RSD-6 0.017
egl-18 Protein EGL-18 0.017
shw-3 Protein SHW-3 0.017
ppm-1 Protein PPM-1 0.017
T28C6.7 Protein T28C6.7 0.017
unc-41 Protein UNC-41 0.017
pig-1 Protein PIG-1 0.017
vab-1 Protein VAB-1 0.017
ape-1 Protein APE-1 0.017
lin-36 Protein LIN-36 0.016
srgp-1 Protein SRGP-1 0.016
clr-1 Protein CLR-1 0.016
frm-8 Protein FRM-8 0.016
flh-2 Protein FLH-2 0.015
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Danio rerio
Name Description Probability Func Analog Organism
adrb2a adrenergic receptor, beta 2a 0.035
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.034
rtcd1 RNA terminal phosphate cyclase domain 1 0.026
cldnc claudin c 0.026
vdrb vitamin D receptor b 0.025
zgc:100838 zgc:100838 0.022
sb:cb730 sb:cb730 0.021
cnn2 calponin 2 0.021
rrm2 ribonucleotide reductase M2 polypeptide 0.021
si:ch211-232m7.1 si:ch211-232m7.1 0.021
iqgap1 IQ motif containing GTPase activating protein 1 0.021
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.021
abcf2 ATP-binding cassette, sub-family F (GCN20), member 2 0.021
rxrbb retinoid x receptor, beta b 0.021
tpm4 tropomyosin 4 0.020
zgc:56466 zgc:56466 0.020
ahnak AHNAK nucleoprotein 0.020
epb4.1l4 erythrocyte protein band 4.1-like 4 0.020
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.019
lrrc50 leucine rich repeat containing 50 0.019
sox19a SRY-box containing gene 19a 0.019
sb:eu854 sb:eu854 0.019
zgc:77517 zgc:77517 0.019
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.018
gstal glutathione S-transferase, alpha-like 0.018
msna moesin a 0.018
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.018
diaph2 diaphanous homolog 2 (Drosophila) 0.017
appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.017
slc43a1a solute carrier family 43, member 1a 0.017
si:dkey-6n6.4 si:dkey-6n6.4 0.017
tm9sf2 transmembrane 9 superfamily member 2 0.017
gpc4 glypican 4 0.017
ankrd6 ankyrin repeat domain 6 0.017
zgc:110298 zgc:110298 0.016
creld2 cysteine-rich with EGF-like domains 2 0.016
m17 IL-6 subfamily cytokine M17 0.016
stk38l serine/threonine kinase 38 like 0.016
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.016
foxj1b forkhead box J1b 0.016
casz1 castor zinc finger 1 0.016
sec24c SEC24 family, member C (S. cerevisiae) 0.016
arpc5a actin related protein 2/3 complex, subunit 5A 0.015
kif20bb kinesin family member 20Bb 0.015
clstn1 calsyntenin 1 0.015
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.015
calcrla calcitonin receptor-like a 0.015
dedd1 death effector domain-containing 1 0.015
ephb4b eph receptor B4b 0.015
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.015
depdc1a DEP domain containing 1a 0.015
rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.014
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.014
si:dkeyp-117h8.4 si:dkeyp-117h8.4 0.014
gro2 groucho 2 0.014
si:dkey-97i18.2 si:dkey-97i18.2 0.014
ccna2 cyclin A2 0.014
zgc:112329 zgc:112329 0.014
arpc4 actin related protein 2/3 complex, subunit 4 0.014
usp33 ubiquitin specific peptidase 33 0.014
gng12a guanine nucleotide binding protein (G protein), gamma 12a 0.014
pggt1b protein geranylgeranyltransferase type I, beta subunit 0.014
bactin1 bactin1 0.014
dmbx1b diencephalon/mesencephalon homeobox 1b 0.014
mtp microsomal triglyceride transfer protein 0.014
fyna FYN oncogene related to SRC, FGR, YES a 0.014
fam76b family with sequence similarity 76, member B 0.014
tead1a TEA domain family member 1a 0.014
helt hey-like transcription factor 0.014
im:7137453 im:7137453 0.014
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.014
tp53bp2 tumor protein p53 binding protein, 2 0.014
e4f1 E4F transcription factor 1 0.014
optc opticin 0.014
admp anti-dorsalizing morphogenic protein 0.014
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.014
LOC569045 novel protein similar to vertebrate WD repeat domain 44 (WDR44) 0.014
lifrb leukemia inhibitory factor receptor alpha b 0.013
ap3m2 adaptor-related protein complex 3, mu 2 subunit 0.013
mat2a methionine adenosyltransferase II, alpha 0.013
cyp2p9 cytochrome P450, family 2, subfamily P, polypeptide 9 0.013
rhoaa ras homolog gene family, member Aa 0.013
tipin timeless interacting protein 0.013
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.013
hs3st1l2 heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2 0.013
plxnb2a plexin b2a 0.013
zgc:92683 zgc:92683 0.013
dlst dihydrolipoamide S-succinyltransferase 0.013
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.013
tomm34 translocase of outer mitochondrial membrane 34 0.013
zgc:63587 zgc:63587 0.013
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.013
cd74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.013
angpt1 angiopoietin 1 0.013
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.013
nr1h5 nuclear receptor subfamily 1, group H, member 5 0.013
cotl1 coactosin-like 1 (Dictyostelium) 0.013
stmn2b stathmin-like 2b 0.013
march6 membrane-associated ring finger (C3HC4) 6 0.013
larp6 La ribonucleoprotein domain family, member 6 0.013
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Drosophila melanogaster
Name Description Probability Func Analog Organism
CG8155 CG8155 gene product from transcript CG8155-RA 0.800
cno canoe 0.799
Sos Son of sevenless 0.789
flw flapwing 0.586
Hem HEM-protein 0.526
mbc myoblast city 0.525
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.513
rok Rho-kinase 0.447
plexB plexin B 0.381
Fak56D Focal Adhesion Kinase 0.316
synj synaptojanin 0.283
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.277
Pkn Protein kinase related to protein kinase N 0.256
siz schizo 0.249
lgs legless 0.239
RhoBTB CG5701 gene product from transcript CG5701-RA 0.238
Sbf SET domain binding factor 0.236
Ephrin CG1862 gene product from transcript CG1862-RA 0.225
drpr draper 0.221
CG6509 CG6509 gene product from transcript CG6509-RB 0.215
pod1 CG4532 gene product from transcript CG4532-RF 0.209
puc puckered 0.197
NaCP60E Na channel protein 60E 0.197
baz bazooka 0.193
sima similar 0.187
stai stathmin 0.182
tbce tubulin-specific chaperone E 0.169
Pten CG5671 gene product from transcript CG5671-RB 0.168
Mad Mothers against dpp 0.162
drk downstream of receptor kinase 0.160
stg string 0.153
dia diaphanous 0.148
nwk nervous wreck 0.146
Ras85D Ras oncogene at 85D 0.141
ena enabled 0.135
CG7158 CG7158 gene product from transcript CG7158-RA 0.133
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.131
Prp31 CG6876 gene product from transcript CG6876-RA 0.128
Abi Abelson interacting protein 0.126
Hr96 Hormone receptor-like in 96 0.117
sec6 CG5341 gene product from transcript CG5341-RA 0.116
smo smoothened 0.110
RN-tre tre oncogene-related protein 0.107
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.101
CG5798 CG5798 gene product from transcript CG5798-RA 0.097
Apc APC-like 0.097
neur neuralized 0.093
kuz kuzbanian 0.089
Hnf4 Hepatocyte nuclear factor 4 0.089
G9a CG2995 gene product from transcript CG2995-RA 0.087
sn singed 0.087
Stat92E Signal-transducer and activator of transcription protein at 92E 0.083
Wnk CG7177 gene product from transcript CG7177-RA 0.083
CG1233 CG1233 gene product from transcript CG1233-RB 0.081
LIMK1 LIM-kinase1 0.081
alpha-Man-II alpha Mannosidase II 0.081
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.078
N Notch 0.075
cenG1A centaurin gamma 1A 0.074
p120ctn Adherens junction protein p120 0.072
CG8334 CG8334 gene product from transcript CG8334-RA 0.070
l(2)k16918 lethal (2) k16918 0.070
Su(H) Suppressor of Hairless 0.069
neuroligin CG13772 gene product from transcript CG13772-RA 0.068
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.067
Graf CG8948 gene product from transcript CG8948-RB 0.067
CG4552 CG4552 gene product from transcript CG4552-RA 0.067
Git CG16728 gene product from transcript CG16728-RA 0.067
Tsc1 CG6147 gene product from transcript CG6147-RA 0.066
dnc dunce 0.066
CG9941 CG9941 gene product from transcript CG9941-RA 0.066
CG11851 CG11851 gene product from transcript CG11851-RA 0.065
dik diskette 0.064
Mtl Mig-2-like 0.060
cher cheerio 0.060
SCAR CG4636 gene product from transcript CG4636-RA 0.058
pcx pecanex 0.058
Vps45 Vacuolar protein sorting 45 0.057
Traf4 TNF-receptor-associated factor 4 0.056
Flo-2 flotillin 2 0.055
CG15099 CG15099 gene product from transcript CG15099-RA 0.055
rl rolled 0.054
NELF-A CG5874 gene product from transcript CG5874-RA 0.054
raps rapsynoid 0.054
l(2)k05819 lethal (2) k05819 0.054
vav CG7893 gene product from transcript CG7893-RB 0.053
mop myopic 0.053
tutl turtle 0.053
Pli Pellino 0.053
Dap160 Dynamin associated protein 160 0.052
ken ken and barbie 0.051
Pak3 CG14895 gene product from transcript CG14895-RA 0.050
CG10631 CG10631 gene product from transcript CG10631-RA 0.049
Mrtf Myocardin-related transcription factor 0.049
mbt mushroom bodies tiny 0.048
shark Src homology 2, ankyrin repeat, tyrosine kinase 0.047
CG14869 CG14869 gene product from transcript CG14869-RB 0.047
mago mago nashi 0.047
G-ialpha65A G protein alphai subunit 65A 0.046
dos daughter of sevenless 0.046
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Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.999
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.999
EGFR epidermal growth factor receptor 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.998
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.997
SFN stratifin 0.996
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.993
TSC2 tuberous sclerosis 2 0.989
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.986
RHOA ras homolog gene family, member A 0.977
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.974
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.969
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.965
SH3KBP1 SH3-domain kinase binding protein 1 0.964
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.957
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.956
NCF2 neutrophil cytosolic factor 2 0.951
ARRB1 arrestin, beta 1 0.944
S100A8 S100 calcium binding protein A8 0.939
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.912
GRB7 growth factor receptor-bound protein 7 0.870
BCAR1 breast cancer anti-estrogen resistance 1 0.865
NCKAP1 NCK-associated protein 1 0.864
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.861
PTK2 PTK2 protein tyrosine kinase 2 0.848
MARK3 MAP/microtubule affinity-regulating kinase 3 0.845
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.844
SH3BP2 SH3-domain binding protein 2 0.830
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.820
ABI1 abl-interactor 1 0.815
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.810
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.774
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.763
S100A9 S100 calcium binding protein A9 0.746
SPRR2A small proline-rich protein 2A 0.740
IGF1R insulin-like growth factor 1 receptor 0.736
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.733
NCK1 NCK adaptor protein 1 0.711
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.708
CCR5 chemokine (C-C motif) receptor 5 0.705
PLCG1 phospholipase C, gamma 1 0.701
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.699
MYO9B myosin IXB 0.695
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.694
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.631
S100A11 S100 calcium binding protein A11 0.618
KIF5B kinesin family member 5B 0.611
LAT linker for activation of T cells 0.592
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.585
ARRB2 arrestin, beta 2 0.584
FMNL1 formin-like 1 0.581
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.569
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.558
CCL5 chemokine (C-C motif) ligand 5 0.553
CCL2 chemokine (C-C motif) ligand 2 0.551
MPRIP myosin phosphatase Rho interacting protein 0.539
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.535
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.535
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.534
RND1 Rho family GTPase 1 0.530
DOCK1 dedicator of cytokinesis 1 0.523
SH3RF1 SH3 domain containing ring finger 1 0.523
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.522
RHOC ras homolog gene family, member C 0.516
PLXNB1 plexin B1 0.502
RABGAP1 RAB GTPase activating protein 1 0.490
NCF4 neutrophil cytosolic factor 4, 40kDa 0.480
JUN jun proto-oncogene 0.474
RIN1 Ras and Rab interactor 1 0.474
RACGAP1 Rac GTPase activating protein 1 0.474
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.472
TRAF5 TNF receptor-associated factor 5 0.470
ESR1 estrogen receptor 1 0.467
SMAD2 SMAD family member 2 0.467
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.466
PKN3 protein kinase N3 0.456
BAIAP2 BAI1-associated protein 2 0.453
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.442
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.439
EZR ezrin 0.437
FOS FBJ murine osteosarcoma viral oncogene homolog 0.435
ADRBK1 adrenergic, beta, receptor kinase 1 0.427
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.422
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.420
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.419
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.417
CDK17 cyclin-dependent kinase 17 0.413
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.410
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.405
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.405
CSNK1G2 casein kinase 1, gamma 2 0.394
ANXA2 annexin A2 0.393
PKP4 plakophilin 4 0.388
DSP desmoplakin 0.383
ANK1 ankyrin 1, erythrocytic 0.382
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Nckap1 NCK-associated protein 1 0.184
Dock9 dedicator of cytokinesis 9 0.088
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.067
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.062
Epas1 endothelial PAS domain protein 1 0.057
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.056
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.054
Anxa2 annexin A2 0.052
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.051
Dlg3 discs, large homolog 3 (Drosophila) 0.047
Bin2 bridging integrator 2 0.045
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.042
Tek TEK tyrosine kinase, endothelial 0.041
Fmnl1 formin-like 1 0.040
Ylpm1 YLP motif containing 1 0.039
Atf3 activating transcription factor 3 0.038
Inpp5d inositol polyphosphate-5-phosphatase D 0.037
Adar adenosine deaminase, RNA-specific 0.036
Arpc5 actin related protein 2/3 complex, subunit 5 0.034
Macf1 microtubule-actin crosslinking factor 1 0.034
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.034
Plcg1 phospholipase C, gamma 1 0.033
Cyth1 cytohesin 1 0.032
Sbf1 SET binding factor 1 0.031
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.030
Pld2 phospholipase D2 0.030
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.029
Zfp36 zinc finger protein 36 0.028
Dusp1 dual specificity phosphatase 1 0.027
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.026
Klf6 Kruppel-like factor 6 0.026
Anxa1 annexin A1 0.026
Cfp complement factor properdin 0.025
Gpr116 G protein-coupled receptor 116 0.025
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.025
Vps52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.025
Pde2a phosphodiesterase 2A, cGMP-stimulated 0.024
Shank3 SH3 and multiple ankyrin repeat domains 3 0.024
Hk1 hexokinase 1 0.024
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.023
Fam108a1 family with sequence similarity 108, member A1 0.023
Plxnd1 plexin D1 0.023
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.023
Junb jun B proto-oncogene 0.023
Prkcb protein kinase C, beta 0.023
Kif16b kinesin family member 16B 0.022
Rap1b RAP1B, member of RAS oncogene family 0.022
Add3 adducin 3 (gamma) 0.022
Strn striatin, calmodulin binding protein 0.022
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.022
Abr active BCR-related gene 0.022
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.022
Jak1 Janus kinase 1 0.021
Opcml opioid binding protein/cell adhesion molecule-like 0.021
Galnt10 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) 0.021
Arpc2 actin related protein 2/3 complex, subunit 2 0.021
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.021
Mmp17 matrix metallopeptidase 17 0.021
LOC100360150 eukaryotic translation elongation factor 1 alpha 2 0.021
Sirpa signal-regulatory protein alpha 0.021
Arhgap4 Rho GTPase activating protein 4 0.021
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.021
Mcf2l MCF.2 cell line derived transforming sequence-like 0.021
Coro2b coronin, actin binding protein, 2B 0.021
Cyyr1 cysteine/tyrosine-rich 1 0.021
Unc13b unc-13 homolog B (C. elegans) 0.021
Bspry B-box and SPRY domain containing 0.021
Dok1 docking protein 1 0.020
Rara retinoic acid receptor, alpha 0.020
Ccdc85b coiled-coil domain containing 85B 0.020
Clcn7 chloride channel 7 0.020
Fnbp1 formin binding protein 1 0.020
Gria2 glutamate receptor, ionotropic, AMPA 2 0.020
Lcp2 lymphocyte cytosolic protein 2 0.019
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.019
S100a4 S100 calcium-binding protein A4 0.019
Ciita class II, major histocompatibility complex, transactivator 0.019
Plekha6 pleckstrin homology domain containing, family A member 6 0.019
Prkch protein kinase C, eta 0.019
Syn2 synapsin II 0.019
Fgd2 FYVE, RhoGEF and PH domain containing 2 0.018
Ccl2 chemokine (C-C motif) ligand 2 0.018
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.018
Ssh3 slingshot homolog 3 (Drosophila) 0.018
Capn2 calpain 2 0.018
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.018
Fgfr3 fibroblast growth factor receptor 3 0.018
Epb41l1 erythrocyte membrane protein band 4.1-like 1 0.018
LOC691920 similar to kinesin-like motor protein C20orf23 0.018
Tspan18 tetraspanin 18 0.018
Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 0.018
Slit3 slit homolog 3 (Drosophila) 0.017
Lphn2 latrophilin 2 0.017
Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.017
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.017
Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.017
Shank2 SH3 and multiple ankyrin repeat domains 2 0.017
RGD621098 similar to RIKEN cDNA D230025D16Rik 0.017
Abi3 ABI family, member 3 0.017
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.016
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MKK1 Mkk1p 0.607
GYL1 Gyl1p 0.311
STE5 Ste5p 0.250
RHO1 Rho1p 0.250
STE11 Ste11p 0.249
IRA1 Ira1p 0.237
SPA2 Spa2p 0.195
BEM3 Bem3p 0.194
PKC1 Pkc1p 0.190
ROM2 Rom2p 0.153
CDC24 Cdc24p 0.103
SAC7 Sac7p 0.077
MDS3 Mds3p 0.071
ACK1 Ack1p 0.065
SLG1 Slg1p 0.065
FYV8 Fyv8p 0.063
VPS41 Vps41p 0.057
MNN9 Mnn9p 0.055
FMS1 Fms1p 0.051
GIC2 Gic2p 0.048
YIP3 Yip3p 0.045
CHS1 Chs1p 0.044
SLT2 Slt2p 0.042
YIL055C hypothetical protein 0.041
YPT53 Ypt53p 0.037
SSK1 Ssk1p 0.036
AKL1 Akl1p 0.036
MSG5 Msg5p 0.035
GPB2 Gpb2p 0.035
PRS2 Prs2p 0.035
HRP1 Hrp1p 0.033
NVJ1 Nvj1p 0.032
PTP2 Ptp2p 0.031
CDC25 Cdc25p 0.031
CMK2 Cmk2p 0.030
TOM1 Tom1p 0.028
AVO1 Avo1p 0.028
FAA2 Faa2p 0.028
YDL206W hypothetical protein 0.028
RGD1 Rgd1p 0.026
TUS1 Tus1p 0.026
SEC3 Sec3p 0.025
INO2 Ino2p 0.025
GPR1 Gpr1p 0.025
FAR1 Far1p 0.025
CRM1 Crm1p 0.025
YPL066W hypothetical protein 0.024
ATG13 Atg13p 0.024
BCK1 Bck1p 0.024
SRP54 Srp54p 0.024
KAP120 Kap120p 0.024
STT4 Stt4p 0.024
BPT1 Bpt1p 0.024
SSK2 Ssk2p 0.024
SPR6 Spr6p 0.023
URA3 Ura3p 0.023
TSC11 Tsc11p 0.023
BEM2 Bem2p 0.023
YLR264C-A hypothetical protein 0.023
SKT5 Skt5p 0.022
CRG1 Crg1p 0.022
SRD1 Srd1p 0.022
SVF1 Svf1p 0.022
YML002W hypothetical protein 0.022
VPS15 Vps15p 0.022
FMP27 Fmp27p 0.022
ARP10 Arp10p 0.021
CYK3 Cyk3p 0.021
ENT1 Ent1p 0.021
YDR186C hypothetical protein 0.021
SKM1 Skm1p 0.021
BST1 Bst1p 0.021
YOL038C-A hypothetical protein 0.021
YGR126W hypothetical protein 0.021
PPE1 Ppe1p 0.021
UBP5 Ubp5p 0.021
LEU2 Leu2p 0.020
AVL9 Avl9p 0.020
IRA2 Ira2p 0.020
INN1 Inn1p 0.019
GDI1 Gdi1p 0.019
YLR162W hypothetical protein 0.019
PEP5 Pep5p 0.019
GIP2 Gip2p 0.019
CUP2 Cup2p 0.019
MER1 Mer1p 0.019
ARG8 Arg8p 0.018
SEC15 Sec15p 0.018
EDE1 Ede1p 0.018
REV1 Rev1p 0.018
ALY2 Aly2p 0.018
HAL5 Hal5p 0.018
YPR148C hypothetical protein 0.018
YAR068W hypothetical protein 0.017
RGD2 Rgd2p 0.017
CUP1-1 Cup1-1p 0.017
BUD8 Bud8p 0.017
ZPS1 Zps1p 0.017
NEO1 Neo1p 0.017
HOR2 Hor2p 0.017