IMP
Process View
The network for 'septum primum development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
septum primum development
The progression of the septum primum over time, from its formation to the mature structure.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gata4 | GATA binding protein 4 | 1.000 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 1.000 | |
| Jag1 | jagged 1 | 0.999 | |
| Fgf8 | fibroblast growth factor 8 | 0.998 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.996 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.995 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.995 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.994 | |
| Pax3 | paired box gene 3 | 0.991 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.986 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.981 | |
| Bmp4 | bone morphogenetic protein 4 | 0.974 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.968 | |
| Shh | sonic hedgehog | 0.958 | |
| Smo | smoothened homolog (Drosophila) | 0.946 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.943 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.912 | |
| Vegfa | vascular endothelial growth factor A | 0.909 | |
| Sox4 | SRY-box containing gene 4 | 0.894 | |
| Tbx3 | T-box 3 | 0.893 | |
| Gata6 | GATA binding protein 6 | 0.893 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.886 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.850 | |
| Rxra | retinoid X receptor alpha | 0.843 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.842 | |
| Mesp1 | mesoderm posterior 1 | 0.830 | |
| She | src homology 2 domain-containing transforming protein E | 0.827 | |
| Meox2 | mesenchyme homeobox 2 | 0.796 | |
| Sox7 | SRY-box containing gene 7 | 0.681 | |
| Ntf3 | neurotrophin 3 | 0.654 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.626 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.623 | |
| Fgf3 | fibroblast growth factor 3 | 0.613 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.611 | |
| Pax6 | paired box gene 6 | 0.610 | |
| Foxc2 | forkhead box C2 | 0.601 | |
| Tbx5 | T-box 5 | 0.565 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.548 | |
| Nf1 | neurofibromatosis 1 | 0.515 | |
| Sox18 | SRY-box containing gene 18 | 0.505 | |
| Sox9 | SRY-box containing gene 9 | 0.497 | |
| Alx4 | aristaless-like homeobox 4 | 0.493 | |
| Pcdh12 | protocadherin 12 | 0.491 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.485 | |
| Msx1 | homeobox, msh-like 1 | 0.480 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.472 | |
| Gja1 | gap junction protein, alpha 1 | 0.452 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.452 | |
| Tbx1 | T-box 1 | 0.444 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.434 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.413 | |
| Gjb2 | gap junction protein, beta 2 | 0.408 | |
| Aplnr | apelin receptor | 0.404 | |
| Cldn5 | claudin 5 | 0.399 | |
| Prrx1 | paired related homeobox 1 | 0.391 | |
| Atoh7 | atonal homolog 7 (Drosophila) | 0.385 | |
| Foxf1a | forkhead box F1a | 0.365 | |
| Ednra | endothelin receptor type A | 0.364 | |
| Tcfap2c | transcription factor AP-2, gamma | 0.360 | |
| Bmp2 | bone morphogenetic protein 2 | 0.355 | |
| Sox17 | SRY-box containing gene 17 | 0.352 | |
| Apc | adenomatosis polyposis coli | 0.346 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.324 | |
| Tbx2 | T-box 2 | 0.314 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.294 | |
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.272 | |
| Foxc1 | forkhead box C1 | 0.270 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.255 | |
| Tcf15 | transcription factor 15 | 0.249 | |
| Gjb6 | gap junction protein, beta 6 | 0.241 | |
| Hoxd13 | homeobox D13 | 0.240 | |
| Msx2 | homeobox, msh-like 2 | 0.237 | |
| Alx3 | aristaless-like homeobox 3 | 0.234 | |
| Podxl | podocalyxin-like | 0.232 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.232 | |
| Sall4 | sal-like 4 (Drosophila) | 0.231 | |
| Gpc3 | glypican 3 | 0.227 | |
| Ryr2 | ryanodine receptor 2, cardiac | 0.226 | |
| Kel | Kell blood group | 0.218 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.215 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.210 | |
| Rara | retinoic acid receptor, alpha | 0.209 | |
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.208 | |
| Ppara | peroxisome proliferator activated receptor alpha | 0.195 | |
| Btbd17 | BTB (POZ) domain containing 17 | 0.193 | |
| Fgf10 | fibroblast growth factor 10 | 0.189 | |
| Kdr | kinase insert domain protein receptor | 0.186 | |
| Foxd2 | forkhead box D2 | 0.182 | |
| Thrb | thyroid hormone receptor beta | 0.180 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.174 | |
| Fut2 | fucosyltransferase 2 | 0.168 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.155 | |
| Alx1 | ALX homeobox 1 | 0.153 | |
| Cdh5 | cadherin 5 | 0.150 | |
| Efna1 | ephrin A1 | 0.147 | |
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.147 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.142 | |
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.141 | |
| Rasip1 | Ras interacting protein 1 | 0.141 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.137 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.973 | |
| TGFB1 | transforming growth factor, beta 1 | 0.970 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.868 | |
| BMP2 | bone morphogenetic protein 2 | 0.777 | |
| ENG | endoglin | 0.616 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.369 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.352 | |
| FSTL1 | follistatin-like 1 | 0.333 | |
| TGFB3 | transforming growth factor, beta 3 | 0.333 | |
| SMAD7 | SMAD family member 7 | 0.293 | |
| ACVR1 | activin A receptor, type I | 0.233 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.178 | |
| NRP1 | neuropilin 1 | 0.131 | |
| GDF5 | growth differentiation factor 5 | 0.115 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.094 | |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.079 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.061 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.031 | |
| TGFBR3 | transforming growth factor, beta receptor III | 0.028 | |
| AR | androgen receptor | 0.024 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.022 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.017 | |
| SMAD2 | SMAD family member 2 | 0.015 | |
| BMP4 | bone morphogenetic protein 4 | 0.015 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.015 | |
| MARCKSL1 | MARCKS-like 1 | 0.015 | |
| SMAD1 | SMAD family member 1 | 0.014 | |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.014 | |
| CKAP5 | cytoskeleton associated protein 5 | 0.013 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.012 | |
| PDGFC | platelet derived growth factor C | 0.012 | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.012 | |
| TBX5 | T-box 5 | 0.011 |