Process View
The network for 'heat generation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.991 | |
| Tnf | tumor necrosis factor | 0.990 | |
| Lta | lymphotoxin A | 0.927 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.755 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.703 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.688 | |
| ND6 | NADH dehydrogenase subunit 6 | 0.626 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.620 | |
| Cd40 | CD40 antigen | 0.611 | |
| Adrb3 | adrenergic receptor, beta 3 | 0.602 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.566 | |
| LOC100048884 | novel member of the major urinary protein (Mup) gene family | 0.407 | |
| Il10 | interleukin 10 | 0.362 | |
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.312 | |
| Mup10 | major urinary protein 10 | 0.292 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.267 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.258 | |
| Il6 | interleukin 6 | 0.255 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.238 | |
| Mup19 | major urinary protein 19 | 0.218 | |
| Mup9 | major urinary protein 9 | 0.208 | |
| Mup1 | major urinary protein 1 | 0.199 | |
| Kl | klotho | 0.193 | |
| Mup12 | major urinary protein 12 | 0.192 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.191 | |
| Adrb1 | adrenergic receptor, beta 1 | 0.182 | |
| Ltb | lymphotoxin B | 0.167 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.167 | |
| Il1r1 | interleukin 1 receptor, type I | 0.153 | |
| Mup15 | major urinary protein 15 | 0.147 | |
| Il1b | interleukin 1 beta | 0.146 | |
| Mup13 | major urinary protein 13 | 0.145 | |
| Mup8 | major urinary protein 8 | 0.137 | |
| Mup17 | major urinary protein 17 | 0.133 | |
| Npy1r | neuropeptide Y receptor Y1 | 0.132 | |
| Mup14 | major urinary protein 14 | 0.132 | |
| Ren1 | renin 1 structural | 0.128 | |
| Mup7 | major urinary protein 7 | 0.124 | |
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.116 | |
| Cd40lg | CD40 ligand | 0.103 | |
| Mup2 | major urinary protein 2 | 0.102 | |
| Mup11 | major urinary protein 11 | 0.096 | |
| Tlr4 | toll-like receptor 4 | 0.092 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.092 | |
| LOC100048885 | major urinary protein LOC100048885 | 0.085 | |
| Plat | plasminogen activator, tissue | 0.085 | |
| Il12b | interleukin 12b | 0.083 | |
| Il4 | interleukin 4 | 0.082 | |
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.072 | |
| Esr2 | estrogen receptor 2 (beta) | 0.072 | |
| Il1a | interleukin 1 alpha | 0.070 | |
| Htr4 | 5 hydroxytryptamine (serotonin) receptor 4 | 0.069 | |
| Mup5 | major urinary protein 5 | 0.060 | |
| Ifng | interferon gamma | 0.059 | |
| Oprm1 | opioid receptor, mu 1 | 0.054 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.054 | |
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.051 | |
| Mup4 | major urinary protein 4 | 0.050 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.045 | |
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.045 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.044 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.044 | |
| Sstr3 | somatostatin receptor 3 | 0.040 | |
| Tnfsf4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.040 | |
| Nhedc2 | Na+/H+ exchanger domain containing 2 | 0.039 | |
| Grm2 | glutamate receptor, metabotropic 2 | 0.039 | |
| Cldn16 | claudin 16 | 0.036 | |
| Il22 | interleukin 22 | 0.036 | |
| Clec4d | C-type lectin domain family 4, member d | 0.035 | |
| Adora2a | adenosine A2a receptor | 0.035 | |
| Cd160 | CD160 antigen | 0.034 | |
| Lepr | leptin receptor | 0.034 | |
| Hrk | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.033 | |
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.033 | |
| Apoe | apolipoprotein E | 0.032 | |
| Sstr1 | somatostatin receptor 1 | 0.031 | |
| Glycam1 | glycosylation dependent cell adhesion molecule 1 | 0.031 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.029 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.027 | |
| Spp1 | secreted phosphoprotein 1 | 0.027 | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.027 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.026 | |
| Erbb4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.026 | |
| Tlr6 | toll-like receptor 6 | 0.026 | |
| Pdcd1 | programmed cell death 1 | 0.026 | |
| Gpr132 | G protein-coupled receptor 132 | 0.026 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.026 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.025 | |
| Edn1 | endothelin 1 | 0.025 | |
| Htra3 | HtrA serine peptidase 3 | 0.024 | |
| Itga2 | integrin alpha 2 | 0.024 | |
| Hamp | hepcidin antimicrobial peptide | 0.024 | |
| Npy5r | neuropeptide Y receptor Y5 | 0.024 | |
| Clcnka | chloride channel Ka | 0.024 | |
| Fpr2 | formyl peptide receptor 2 | 0.023 | |
| Cd70 | CD70 antigen | 0.023 | |
| Dmbx1 | diencephalon/mesencephalon homeobox 1 | 0.022 | |
| Traf2 | TNF receptor-associated factor 2 | 0.022 | |
| Adrb2 | adrenergic receptor, beta 2 | 0.022 | |
| Fndc7 | fibronectin type III domain containing 7 | 0.022 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Il1a | interleukin 1 alpha | 0.234 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.115 | |
| Cd14 | CD14 molecule | 0.067 | |
| Il6 | interleukin 6 | 0.066 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.062 | |
| Gzmk | granzyme K | 0.048 | |
| Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.043 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.042 | |
| RT1-Ba | RT1 class II, locus Ba | 0.041 | |
| Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.033 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.028 | |
| F13a1 | coagulation factor XIII, A1 polypeptide | 0.020 | |
| Il1rn | interleukin 1 receptor antagonist | 0.020 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.019 | |
| Tgm1 | transglutaminase 1, K polypeptide | 0.018 | |
| Cdh6 | cadherin 6 | 0.018 | |
| LOC685020 | similar to paired immunoglobin-like type 2 receptor alpha | 0.017 | |
| Calcrl | calcitonin receptor-like | 0.017 | |
| Gabrg1 | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 0.016 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.015 | |
| Nkg7 | natural killer cell group 7 sequence | 0.015 | |
| Clcn5 | chloride channel 5 | 0.014 | |
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.014 | |
| RT1-Bb | RT1 class II, locus Bb | 0.014 | |
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.013 | |
| Aqp4 | aquaporin 4 | 0.013 | |
| Grxcr1 | glutaredoxin, cysteine rich 1 | 0.013 | |
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.013 | |
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.012 | |
| Ptger4 | prostaglandin E receptor 4 (subtype EP4) | 0.012 | |
| Bcl2a1d | B-cell leukemia/lymphoma 2 related protein A1d | 0.012 | |
| Casp1 | caspase 1 | 0.012 | |
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.011 | |
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.011 | |
| Rab32 | RAB32, member RAS oncogene family | 0.011 | |
| Fosl1 | fos-like antigen 1 | 0.011 | |
| Nlgn1 | neuroligin 1 | 0.011 | |
| Gzmb | granzyme B | 0.010 |