IMP
Process View
The network for 'innate immune response activating cell surface receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
innate immune response activating cell surface receptor signaling pathway
Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.999 | |
| Il10 | interleukin 10 | 0.994 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.990 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.990 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.950 | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.946 | |
| Gzma | granzyme A | 0.897 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.884 | |
| Tlr2 | toll-like receptor 2 | 0.867 | |
| Gzmk | granzyme K | 0.843 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.832 | |
| Spp1 | secreted phosphoprotein 1 | 0.808 | |
| Tlr4 | toll-like receptor 4 | 0.803 | |
| Cd180 | CD180 antigen | 0.757 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.712 | |
| Klra7 | killer cell lectin-like receptor, subfamily A, member 7 | 0.702 | |
| Klra2 | killer cell lectin-like receptor, subfamily A, member 2 | 0.682 | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.572 | |
| Il18r1 | interleukin 18 receptor 1 | 0.500 | |
| Pyhin1 | pyrin and HIN domain family, member 1 | 0.493 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.441 | |
| Fcrla | Fc receptor-like A | 0.439 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.437 | |
| Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 0.435 | |
| Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 | 0.415 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.392 | |
| Ifng | interferon gamma | 0.364 | |
| Aoah | acyloxyacyl hydrolase | 0.336 | |
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.314 | |
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.301 | |
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.291 | |
| Gzmb | granzyme B | 0.290 | |
| Cd22 | CD22 antigen | 0.274 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.264 | |
| Lepr | leptin receptor | 0.261 | |
| Icos | inducible T-cell co-stimulator | 0.253 | |
| Klra3 | killer cell lectin-like receptor, subfamily A, member 3 | 0.247 | |
| Sell | selectin, lymphocyte | 0.243 | |
| BC013712 | cDNA sequence BC013712 | 0.242 | |
| Klrb1c | killer cell lectin-like receptor subfamily B member 1C | 0.241 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.236 | |
| Fpr1 | formyl peptide receptor 1 | 0.234 | |
| F2rl2 | coagulation factor II (thrombin) receptor-like 2 | 0.230 | |
| Ccr3 | chemokine (C-C motif) receptor 3 | 0.222 | |
| Blk | B lymphoid kinase | 0.217 | |
| Sh2d1a | SH2 domain protein 1A | 0.213 | |
| Slamf7 | SLAM family member 7 | 0.209 | |
| Casp1 | caspase 1 | 0.207 | |
| Cd7 | CD7 antigen | 0.206 | |
| Ly9 | lymphocyte antigen 9 | 0.203 | |
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.196 | |
| Il7r | interleukin 7 receptor | 0.187 | |
| Irak4 | interleukin-1 receptor-associated kinase 4 | 0.187 | |
| Itk | IL2-inducible T-cell kinase | 0.181 | |
| Clec4n | C-type lectin domain family 4, member n | 0.169 | |
| Itgax | integrin alpha X | 0.169 | |
| Ciita | class II transactivator | 0.165 | |
| Cd96 | CD96 antigen | 0.164 | |
| Igk | immunoglobulin kappa chain complex | 0.163 | |
| Fpr2 | formyl peptide receptor 2 | 0.162 | |
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.157 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.144 | |
| Mmp9 | matrix metallopeptidase 9 | 0.144 | |
| Il6 | interleukin 6 | 0.135 | |
| Ly96 | lymphocyte antigen 96 | 0.133 | |
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.131 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.131 | |
| Il1a | interleukin 1 alpha | 0.126 | |
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.124 | |
| Nkg7 | natural killer cell group 7 sequence | 0.120 | |
| Il1b | interleukin 1 beta | 0.117 | |
| Cd2 | CD2 antigen | 0.115 | |
| Clec4d | C-type lectin domain family 4, member d | 0.114 | |
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.114 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.111 | |
| Ctsw | cathepsin W | 0.110 | |
| Klrb1f | killer cell lectin-like receptor subfamily B member 1F | 0.108 | |
| Bex6 | brain expressed gene 6 | 0.105 | |
| Slfn4 | schlafen 4 | 0.104 | |
| Klrb1a | killer cell lectin-like receptor subfamily B member 1A | 0.102 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.099 | |
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.099 | |
| Irg1 | immunoresponsive gene 1 | 0.099 | |
| Cd44 | CD44 antigen | 0.099 | |
| Fcgr4 | Fc receptor, IgG, low affinity IV | 0.099 | |
| Gcet2 | germinal center expressed transcript 2 | 0.095 | |
| Cxcr6 | chemokine (C-X-C motif) receptor 6 | 0.093 | |
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.092 | |
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.090 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.090 | |
| Rgs18 | regulator of G-protein signaling 18 | 0.089 | |
| Cd14 | CD14 antigen | 0.089 | |
| Cd84 | CD84 antigen | 0.087 | |
| Klra8 | killer cell lectin-like receptor, subfamily A, member 8 | 0.086 | |
| Igj | immunoglobulin joining chain | 0.083 | |
| Cd244 | CD244 natural killer cell receptor 2B4 | 0.081 | |
| Itga4 | integrin alpha 4 | 0.079 | |
| Rhag | Rhesus blood group-associated A glycoprotein | 0.078 | |
| Cd33 | CD33 antigen | 0.076 | |
| Clec4a2 | C-type lectin domain family 4, member a2 | 0.076 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FGB | fibrinogen beta chain | 0.540 | |
| CRP | C-reactive protein, pentraxin-related | 0.274 | |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.087 | |
| HCST | hematopoietic cell signal transducer | 0.050 | |
| FGA | fibrinogen alpha chain | 0.048 | |
| CFP | complement factor properdin | 0.047 | |
| CLEC4A | C-type lectin domain family 4, member A | 0.042 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.041 | |
| S100A9 | S100 calcium binding protein A9 | 0.034 | |
| HK3 | hexokinase 3 (white cell) | 0.034 | |
| S100A8 | S100 calcium binding protein A8 | 0.032 | |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.031 | |
| PRF1 | perforin 1 (pore forming protein) | 0.028 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.026 | |
| S100A12 | S100 calcium binding protein A12 | 0.024 | |
| ITGB5 | integrin, beta 5 | 0.024 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.022 | |
| FPR1 | formyl peptide receptor 1 | 0.021 | |
| PLEK | pleckstrin | 0.020 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.020 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.019 | |
| IL2RB | interleukin 2 receptor, beta | 0.018 | |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.016 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.016 | |
| MARCO | macrophage receptor with collagenous structure | 0.015 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.014 | |
| CLEC10A | C-type lectin domain family 10, member A | 0.014 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.014 | |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.014 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.014 | |
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.013 | |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.013 | |
| CD2 | CD2 molecule | 0.013 | |
| MASP2 | mannan-binding lectin serine peptidase 2 | 0.013 | |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.013 | |
| CD163 | CD163 molecule | 0.012 | |
| MNDA | myeloid cell nuclear differentiation antigen | 0.012 | |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.012 | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.012 | |
| AQP9 | aquaporin 9 | 0.011 | |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.011 | |
| MICA | MHC class I polypeptide-related sequence A | 0.011 | |
| FPR2 | formyl peptide receptor 2 | 0.011 | |
| FCAR | Fc fragment of IgA, receptor for | 0.011 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.010 | |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.010 | |
| MSR1 | macrophage scavenger receptor 1 | 0.010 |