IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

regulation of regulatory t cell differentiation

GO:0045589

Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of regulatory t cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of regulatory t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-G	major histocompatibility complex, class I, G	1.000
HLA-C	major histocompatibility complex, class I, C	1.000	Human
B2M	beta-2-microglobulin	1.000
HLA-F	major histocompatibility complex, class I, F	1.000	Human
HLA-B	major histocompatibility complex, class I, B	1.000
HLA-E	major histocompatibility complex, class I, E	0.999	Human
HLA-A	major histocompatibility complex, class I, A	0.999	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.998	Human
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.973
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.965
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.960
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.936
TAPBP	TAP binding protein (tapasin)	0.933
PILRA	paired immunoglobin-like type 2 receptor alpha	0.898
CD80	CD80 molecule	0.886
CD86	CD86 molecule	0.722
BTN3A1	butyrophilin, subfamily 3, member A1	0.591
GRAP2	GRB2-related adaptor protein 2	0.587
STAT2	signal transducer and activator of transcription 2, 113kDa	0.531
IRF9	interferon regulatory factor 9	0.491
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.412	Human
BTN3A3	butyrophilin, subfamily 3, member A3	0.363
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.322	Human
IL4R	interleukin 4 receptor	0.271
BTN3A2	butyrophilin, subfamily 3, member A2	0.251
SIGLEC7	sialic acid binding Ig-like lectin 7	0.204
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.162
HCP5	HLA complex P5	0.136
BTN2A1	butyrophilin, subfamily 2, member A1	0.115	Mouse
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.103
HK3	hexokinase 3 (white cell)	0.102
PTAFR	platelet-activating factor receptor	0.102
IL32	interleukin 32	0.098
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.091
CD28	CD28 molecule	0.089	Human
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.085	Human
CPD	carboxypeptidase D	0.077
TAPBPL	TAP binding protein-like	0.076
CD33	CD33 molecule	0.076
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.067
HFE	hemochromatosis	0.065	Human
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.053	Human
BTN2A2	butyrophilin, subfamily 2, member A2	0.053	Mouse
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.047
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.046
ICAM1	intercellular adhesion molecule 1	0.046
CSK	c-src tyrosine kinase	0.043
SIRPB1	signal-regulatory protein beta 1	0.042
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.041
CD300C	CD300c molecule	0.039
NLRP3	NLR family, pyrin domain containing 3	0.038
TREM1	triggering receptor expressed on myeloid cells 1	0.037
ISG20	interferon stimulated exonuclease gene 20kDa	0.036
IL4	interleukin 4	0.036
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.036
HDAC9	histone deacetylase 9	0.036
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.036
CD40	CD40 molecule, TNF receptor superfamily member 5	0.036
EPOR	erythropoietin receptor	0.035
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.035
CD164	CD164 molecule, sialomucin	0.034
AOAH	acyloxyacyl hydrolase (neutrophil)	0.033
VSIG4	V-set and immunoglobulin domain containing 4	0.032
IL2RB	interleukin 2 receptor, beta	0.032
PECAM1	platelet/endothelial cell adhesion molecule	0.031
SIGLEC9	sialic acid binding Ig-like lectin 9	0.030
HDAC7	histone deacetylase 7	0.028
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.028
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.028
SIGLEC10	sialic acid binding Ig-like lectin 10	0.027
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.027
TPP1	tripeptidyl peptidase I	0.027
SNAP23	synaptosomal-associated protein, 23kDa	0.027
P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	0.027
CMKLR1	chemokine-like receptor 1	0.026
FPR2	formyl peptide receptor 2	0.026
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.025	Human
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.025
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.025	Human
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.025
IL10RB	interleukin 10 receptor, beta	0.024
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.024
FCAR	Fc fragment of IgA, receptor for	0.024	Human
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.024
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.024
GPSM3	G-protein signaling modulator 3	0.023
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.022
LBP	lipopolysaccharide binding protein	0.021
GBP5	guanylate binding protein 5	0.021
CD48	CD48 molecule	0.021
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.021
NOD2	nucleotide-binding oligomerization domain containing 2	0.021
TYMP	thymidine phosphorylase	0.021
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.021
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.020
CCR1	chemokine (C-C motif) receptor 1	0.020
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.020
OASL	2'-5'-oligoadenylate synthetase-like	0.019
BEST1	bestrophin 1	0.019
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.019
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.019
LCK	lymphocyte-specific protein tyrosine kinase	0.019
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.018
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.018
PLEK	pleckstrin	0.018
CD27	CD27 molecule	0.018
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.018
FFAR2	free fatty acid receptor 2	0.018
IL2RA	interleukin 2 receptor, alpha	0.018
CYTH4	cytohesin 4	0.018
STK10	serine/threonine kinase 10	0.017
AQP9	aquaporin 9	0.017
IKZF4	IKAROS family zinc finger 4 (Eos)	0.017
CD300A	CD300a molecule	0.017
LAIR2	leukocyte-associated immunoglobulin-like receptor 2	0.017	Human
KIR2DL3	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	0.017
CD72	CD72 molecule	0.016
BIN2	bridging integrator 2	0.016
TLR8	toll-like receptor 8	0.016
ICOS	inducible T-cell co-stimulator	0.016
HAMP	hepcidin antimicrobial peptide	0.016
IL10	interleukin 10	0.016
IL21R	interleukin 21 receptor	0.015
SIGLEC5	sialic acid binding Ig-like lectin 5	0.015
CD5	CD5 molecule	0.015
IRF8	interferon regulatory factor 8	0.015
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.015
DPEP2	dipeptidase 2	0.015
CD22	CD22 molecule	0.015
CNOT8	CCR4-NOT transcription complex, subunit 8	0.015
FMNL1	formin-like 1	0.015
APOBR	apolipoprotein B receptor	0.014
BATF2	basic leucine zipper transcription factor, ATF-like 2	0.014
ASGR2	asialoglycoprotein receptor 2	0.014
SH3BP2	SH3-domain binding protein 2	0.014
EXT2	exostosin 2	0.014
CD274	CD274 molecule	0.014
GNLY	granulysin	0.014
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.014
TM9SF2	transmembrane 9 superfamily member 2	0.014
FOLR3	folate receptor 3 (gamma)	0.014
ARHGAP25	Rho GTPase activating protein 25	0.014
CLEC1B	C-type lectin domain family 1, member B	0.014
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.014
DEFA1B	defensin, alpha 1B	0.014
FPR1	formyl peptide receptor 1	0.013
GPR132	G protein-coupled receptor 132	0.013
IL15RA	interleukin 15 receptor, alpha	0.013
TCN2	transcobalamin II	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
IL10RA	interleukin 10 receptor, alpha	0.013
IL13RA1	interleukin 13 receptor, alpha 1	0.013
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.013
BIRC3	baculoviral IAP repeat containing 3	0.013
MARCO	macrophage receptor with collagenous structure	0.013
CD84	CD84 molecule	0.013
NCKAP1L	NCK-associated protein 1-like	0.013
KIR3DS1	killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1	0.013
CD226	CD226 molecule	0.013
GAB1	GRB2-associated binding protein 1	0.013
NLRC5	NLR family, CARD domain containing 5	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
TF	transferrin	0.013
IFNGR1	interferon gamma receptor 1	0.013
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.012
GIMAP5	GTPase, IMAP family member 5	0.012	Rat
RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	0.012
TBX21	T-box 21	0.012
PSAP	prosaposin	0.012
S100A12	S100 calcium binding protein A12	0.012
APLP1	amyloid beta (A4) precursor-like protein 1	0.012
HBD	hemoglobin, delta	0.012
IFNG	interferon, gamma	0.012
CFLAR	CASP8 and FADD-like apoptosis regulator	0.012
PGCP	plasma glutamate carboxypeptidase	0.012
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.012
IL7	interleukin 7	0.012
ZBP1	Z-DNA binding protein 1	0.012
TLR6	toll-like receptor 6	0.012
F5	coagulation factor V (proaccelerin, labile factor)	0.012
IRF2	interferon regulatory factor 2	0.012
APOL3	apolipoprotein L, 3	0.012
SERINC3	serine incorporator 3	0.012
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.012
SIRPA	signal-regulatory protein alpha	0.012
CST7	cystatin F (leukocystatin)	0.012
PICALM	phosphatidylinositol binding clathrin assembly protein	0.012
IL7R	interleukin 7 receptor	0.012
CD6	CD6 molecule	0.011
PRDM1	PR domain containing 1, with ZNF domain	0.011
BPI	bactericidal/permeability-increasing protein	0.011
LITAF	lipopolysaccharide-induced TNF factor	0.011
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.011
KIR2DL4	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4	0.011
CASS4	Cas scaffolding protein family member 4	0.011
FPR3	formyl peptide receptor 3	0.011
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.011
RIOK3	RIO kinase 3 (yeast)	0.011
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.011
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.011
SP140	SP140 nuclear body protein	0.011
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.011	Human
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.011
CXorf21	chromosome X open reading frame 21	0.011
GPR77	G protein-coupled receptor 77	0.011
JAK3	Janus kinase 3	0.010
CD101	CD101 molecule	0.010
APH1B	anterior pharynx defective 1 homolog B (C. elegans)	0.010
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.010
STAT4	signal transducer and activator of transcription 4	0.010
SLAMF7	SLAM family member 7	0.010
IDO1	indoleamine 2,3-dioxygenase 1	0.010
APOBEC3C	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	0.010
TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	0.010
CD160	CD160 molecule	0.010
SLAMF1	signaling lymphocytic activation molecule family member 1	0.010
PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	0.010
ARG1	arginase, liver	0.010
CTSF	cathepsin F	0.010
HCK	hemopoietic cell kinase	0.010
IL15	interleukin 15	0.010
C1orf38	chromosome 1 open reading frame 38	0.010
RFX5	regulatory factor X, 5 (influences HLA class II expression)	0.010
ORM2	orosomucoid 2	0.010
P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	0.010
ADAM9	ADAM metallopeptidase domain 9	0.010
FGB	fibrinogen beta chain	0.010