IMP

Process View

Homo sapiens

4 genes annotated in human

response to muramyl dipeptide

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to muramyl dipeptide"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to muramyl dipeptide" (in gray)

Name	Description	Probability	Func Analog Organism
BIRC3	baculoviral IAP repeat containing 3	1.000
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.978
STAT2	signal transducer and activator of transcription 2, 113kDa	0.876
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.842
NOTCH3	notch 3	0.674
NOTCH1	notch 1	0.343	Mouse
RIPK3	receptor-interacting serine-threonine kinase 3	0.340	Human
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.313
MARK2	MAP/microtubule affinity-regulating kinase 2	0.301
IRF1	interferon regulatory factor 1	0.265	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.257
TRAF1	TNF receptor-associated factor 1	0.245
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.222
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.200
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.185	Mouse
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.146
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.099
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.094
HLA-A	major histocompatibility complex, class I, A	0.063
NOTCH2	notch 2	0.061
JUN	jun proto-oncogene	0.055
TNIP2	TNFAIP3 interacting protein 2	0.051
GBP5	guanylate binding protein 5	0.050
JAG1	jagged 1	0.048	Mouse
TRAF3	TNF receptor-associated factor 3	0.045
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.037
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.034	Mouse
TRIM21	tripartite motif containing 21	0.033
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.033
ACTB	actin, beta	0.033
ZNFX1	zinc finger, NFX1-type containing 1	0.031
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.028
BCL3	B-cell CLL/lymphoma 3	0.027
NCOA3	nuclear receptor coactivator 3	0.027
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.026
MAP2K6	mitogen-activated protein kinase kinase 6	0.025
TNF	tumor necrosis factor	0.025
ANG	angiogenin, ribonuclease, RNase A family, 5	0.024
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.023
MAML1	mastermind-like 1 (Drosophila)	0.022
EFNB2	ephrin-B2	0.021
XIAP	X-linked inhibitor of apoptosis	0.021
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.021
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.021
KLF5	Kruppel-like factor 5 (intestinal)	0.020
RIPK2	receptor-interacting serine-threonine kinase 2	0.020
CFLAR	CASP8 and FADD-like apoptosis regulator	0.020
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.019
ANKRD28	ankyrin repeat domain 28	0.019
OSBPL3	oxysterol binding protein-like 3	0.018
TRAF2	TNF receptor-associated factor 2	0.018
DUSP1	dual specificity phosphatase 1	0.018
MAP2K1	mitogen-activated protein kinase kinase 1	0.018
IRF6	interferon regulatory factor 6	0.018	Human
CCDC50	coiled-coil domain containing 50	0.018
TRIM22	tripartite motif containing 22	0.017
PRMT2	protein arginine methyltransferase 2	0.017
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.017
MAPK1	mitogen-activated protein kinase 1	0.017
MAP2K3	mitogen-activated protein kinase kinase 3	0.017
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.017	Human
IRF2	interferon regulatory factor 2	0.016
HSPA1L	heat shock 70kDa protein 1-like	0.016
BTN3A1	butyrophilin, subfamily 3, member A1	0.016
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.016
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.016
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.016
TSC1	tuberous sclerosis 1	0.016
IRF8	interferon regulatory factor 8	0.015	Human
FOXO1	forkhead box O1	0.015
RAI14	retinoic acid induced 14	0.015
THRAP3	thyroid hormone receptor associated protein 3	0.015
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.015
CD86	CD86 molecule	0.015
MPRIP	myosin phosphatase Rho interacting protein	0.015
IL15RA	interleukin 15 receptor, alpha	0.014
FAM82A2	family with sequence similarity 82, member A2	0.014
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.014
MYO1D	myosin ID	0.014
ADAR	adenosine deaminase, RNA-specific	0.014
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.014
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.014
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.014
MAX	MYC associated factor X	0.013
RNF168	ring finger protein 168	0.013
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.013
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.013
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.013
RNF19B	ring finger protein 19B	0.013
YAP1	Yes-associated protein 1	0.013
TRIM38	tripartite motif containing 38	0.013
POLH	polymerase (DNA directed), eta	0.013
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.013
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.013
MAPK3	mitogen-activated protein kinase 3	0.013
HMHA1	histocompatibility (minor) HA-1	0.013
HCP5	HLA complex P5	0.013
ETV6	ets variant 6	0.013
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.012
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.012
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.012
KIF2B	kinesin family member 2B	0.012
NOD1	nucleotide-binding oligomerization domain containing 1	0.012
TRADD	TNFRSF1A-associated via death domain	0.012
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.012
RUNX3	runt-related transcription factor 3	0.012
TIAM1	T-cell lymphoma invasion and metastasis 1	0.012
DTX3L	deltex 3-like (Drosophila)	0.012
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.012
C14orf43	chromosome 14 open reading frame 43	0.012
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.011
DLL1	delta-like 1 (Drosophila)	0.011
DUSP7	dual specificity phosphatase 7	0.011
DUSP16	dual specificity phosphatase 16	0.011
SH3BP4	SH3-domain binding protein 4	0.011
STK10	serine/threonine kinase 10	0.011
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.011
C10orf46	chromosome 10 open reading frame 46	0.011
NLRP9	NLR family, pyrin domain containing 9	0.011	Human
KIAA0930	KIAA0930	0.011
EP300	E1A binding protein p300	0.011
RHOA	ras homolog gene family, member A	0.011
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.011
ZFAND5	zinc finger, AN1-type domain 5	0.011
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.011
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.011
ZAN	zonadhesin	0.011
DIABLO	diablo, IAP-binding mitochondrial protein	0.011
C19orf66	chromosome 19 open reading frame 66	0.011
DDIT4	DNA-damage-inducible transcript 4	0.011
ANKRD13A	ankyrin repeat domain 13A	0.011
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.010
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.010
ARHGAP9	Rho GTPase activating protein 9	0.010
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.010
STAT5A	signal transducer and activator of transcription 5A	0.010
C5orf56	chromosome 5 open reading frame 56	0.010
TJP2	tight junction protein 2 (zona occludens 2)	0.010
PPP5C	protein phosphatase 5, catalytic subunit	0.010
MAVS	mitochondrial antiviral signaling protein	0.010
GRIP1	glutamate receptor interacting protein 1	0.010
COMMD1	copper metabolism (Murr1) domain containing 1	0.010
RIPK4	receptor-interacting serine-threonine kinase 4	0.010	Human
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.010
FAS	Fas (TNF receptor superfamily, member 6)	0.010
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.010
TRAFD1	TRAF-type zinc finger domain containing 1	0.010
CD83	CD83 molecule	0.010